Patents Represented by Attorney Kathyrn L. Sieburth

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  • Quinoline derivatives and their use as 5-ht6 ligands
    Patent number: 7452888
    Abstract: Disclosed are novel quinoline compounds of formula (I), processes for their preparation, compositions containing them and their use in the treatment of CNS disorders.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: November 18, 2008
    Assignee: Glaxo Group Limited
    Inventors: Mahmood Ahmed, Christopher Norbert Johnson, Martin C Jones, Gregor James Macdonald, Stephen Frederick Moss, Mervyn Thompson, Charles Edward Wade, David R Witty
  • Thiazolidinedione derivative and its use as antidiabetic
    Patent number: 6815457
    Abstract: A polymorphic form of 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]-benzyl]thiazolidine-2,4-dione, maleic acid salt (the “Polymorph”) characterized in that it: (i) provides an infra red spectrum containing peaks at 1360, 1326, 1241, 714 and 669 cm−1; and/or (ii) provides a Raman spectrum containing peaks at 1581, 768, 670, 271 and 226 cm−1; and/or (iii) provides a solid-state nuclear magnetic resonance spectrum containing peaks at chemical shifts substantially as set out in Table I; and/or (iv) provides an X-ray powder diffraction (XRPD) pattern containing peaks substantially as set out in Table II; a process for preparing such a compound, a pharmaceutical composition containing such a compound and the use of such a compound in medicine.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: November 9, 2004
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Paul David James Blackler, Robert Gordon Giles, Michael Sasse