Abstract: Disclosed is a monoclonal antibody having very high affinity to anthrax toxin and potent toxin-neutralizing activity. Also disclosed are a composition for neutralizing anthrax toxin comprising the antibody and a kit for detecting anthrax toxin.
Type:
Grant
Filed:
March 10, 2006
Date of Patent:
September 18, 2012
Assignee:
Aprogen, Inc
Inventors:
Hyo Jeong Hong, Kyung Soo Inn, Nam Kyu Lim, Jung Whan Kim, Keun Soo Kim, Sang Yoon Lee, Se Yeon Kim, Hyun Jung Kang, Mee Sook Oh
Abstract: The invention concerns compositions and methods for preparing recombinant adenoviruses. The resulting adenoviruses can be used for transferring and/or expressing genes in cells, in vitro, ex vivo or in vivo, or also in functional genomics. More particularly, the invention concerns in particular efficient methods for producing adenovirus banks and the use of said banks in functional genomics. The invention also concerns plasmids used for constructing said adenoviruses.
Abstract: The present invention relates generally to labeling, and particularly to retail shelf labels and methods of making the same. A sheet having a retail shelf label according to an embodiment includes a liner, a transparent face layer, and a cover layer having graphics printed thereon. Adhesive couples the face layer atop the liner, and adhesive couples the cover layer atop the face layer. Cut lines in the face and cover layers define a perimeter of the label, and a cut line in the cover layer separates the cover layer into two distinct portions respectively separable from the face layer. At least a portion of the adhesive coupled to the face layer inside the label perimeter releases from the liner to removably couple the label to a shelf edge.
Type:
Grant
Filed:
May 6, 2009
Date of Patent:
September 11, 2012
Assignee:
Vestcom New Century LLC
Inventors:
Mike Wilkinson, Corey Deters, Thomas Paul Eversole
Abstract: Methods and apparatus for treatment of medical disorders such as obstructive sleep apnea and congestive heart failure are disclosed. A method involves delivering pressurized air, oxygen or other breathing gas to a patient during a respiratory cycle, where pressure of the air is decreased according to an expiratory unloading factor during expiration. The timing and magnitude of the pressure change may be fully automated and responsive to feedback from a motor load sensor, optionally in combination with a pressure sensor.
Type:
Grant
Filed:
November 22, 2006
Date of Patent:
September 4, 2012
Assignee:
Curative (Beijing) Medical Technology Co., Ltd.
Abstract: Gliding boards having removable edge sections and methods of modifying gliding boards are disclosed herein. A gliding board of one embodiment includes a board body having top and bottom sides and defining a recessed area therebetween. A plurality of edge sections are removable from and replaceable to the board body, and each edge section has an engaging region complementary to the recessed area of the board body.
Abstract: This invention relates generally to a process for value-added processing of fats and oils to yield glycerol and glycerol derivatives. More particularly, the process converts glycerol to acetol and then acetol to propylene glycol to produce a propylene glycol with ultra-low amounts of ethylene glycol. The propylene glycol thus produced may be used as an antifreeze, deicing compound, or anti-icing compound.
Type:
Grant
Filed:
December 19, 2008
Date of Patent:
August 28, 2012
Assignee:
The Curators of The University of Missouri
Abstract: A method for determining an optimized structure for skin stretch form blocks. An optimized stretch form block design is generated by performing a finite element analysis on a stretch form block design selected from a target group of the stretch form blocks which have been classified into a plurality of groups based on similar topology of the blocks. The finite element analysis includes specifying a suggested design and generating the optimized stretch form block design by iteratively modifying the suggested design until the suggested design has a predetermined sufficient structural strength. An interpolation model is generated from the optimized stretch form block design, and an optimized stretch form block structure is determined for any stretch form block having size and weight parameters within an envelope defined by the target group of the stretch form blocks, by performing a weighted nearest neighbor interpolation using specified geometric parameters and material parameters.
Abstract: The present invention relates to tetraaza phenalen-3-one compounds which inhibit poly (ADP-ribose) polymerase (PARP) and are useful in the chemosensitization of cancer therapeutics. The induction of peripheral neuropathy is a common side-effect of many of the conventional and newer chemotherapies. The present invention further provides means to reliably prevent or cure chemotherapy-induced neuropathy. The invention also relates to the use of the disclosed PARP inhibitor compounds in enhancing the efficacy of chemotherapeutic agents such as temozolomide. The invention also relates to the use of the disclosed PARP inhibitor compounds to radiosensitize tumor cells to ionizing radiation. The invention also relates to the use of the disclosed PARP inhibitor compounds for treatment of cancers with DNA repair defects.
Type:
Grant
Filed:
October 2, 2008
Date of Patent:
August 7, 2012
Assignee:
Eisai Inc.
Inventors:
Weizheng Xu, Greg Delahanty, Ling Wei, Jie Zhang
Abstract: An M-winding coupled inductor includes a first end magnetic element, a second end magnetic element, M connecting magnetic elements, and M windings. M is an integer greater than one. Each connecting magnetic element is disposed between and connects the first and second end magnetic elements. Each winding is wound at least partially around a respective one of the M connecting magnetic elements. The coupled inductor further includes at least one top magnetic element adjacent to and extending at least partially over at least two of the M connecting magnetic elements to provide a magnetic flux path between the first and second end magnetic elements. The inductor may be included in an M-phase power supply, and the power supply may at least partially power a computer processor.
Abstract: A system assesses activity of a sportsman engaged in board sports. At least one sensor detects movement of the sportsman, and a processor processes data from the sensor to assess activity of the sportsman. Activity of sportsmen engaged in human powered sports is compared. A plurality of activity sensing units is associated with the sportsman. Each of the units (a) attach to one of either the sportsman or to a human powered vehicle ridden by the sportsman, and (b) wirelessly communicate activity to a remote location. The activity comprising one or more of airtime, speed, drop distance, power and energy absorbed. A database, accessible by Internet and connected to the remote location, provides access to the activity via the Internet.
Type:
Grant
Filed:
July 25, 2011
Date of Patent:
August 7, 2012
Assignee:
PhatRat Technology, LLP
Inventors:
Curtis A. Vock, Dennis Darcy, Peter Flentov
Abstract: Systems and methods authenticate a device to operate within an enterprise system with an enterprise policy. An agent, installed on the device, analyzes the device to determine profile information of the device. The determined profile information is sent to a type 2 super peer that verifies whether the profile information conforms to the enterprise policy. If the profile information conforms to the enterprise policy, an agent trust credential is generated, within the type 2 super peer, for the agent, based upon the profile information, and issued to the agent. Authenticity of the device is verified based upon the agent trust credential. If the device is authenticated, communications with the device are permitted. If the device is not authenticated, communications with the device is prevented. In another embodiment, a method restores a device to conform to a system policy. A snapshot of critical components of the device is taken while the device is in compliance with the system policy.
Type:
Grant
Filed:
October 30, 2007
Date of Patent:
August 7, 2012
Assignee:
Enterprise Information Management, Inc.
Inventors:
Frank J. Hammond, II, Frank J. Ricotta, Jr., Hans Michael Dykstra, Blake Andrew Williams, Steven James Carlander, Sarah Williams Gerber
Abstract: Polymer-derived nanocomposite lubricants reduce friction and wear in applications involving elevated temperatures, such as within an internal combustion engine.
Abstract: Hyperspectral imaging systems that may be used for imaging objects in three-dimensions with no moving parts are disclosed. A lenslet array and/or a pinhole array may be used to reimage and divide the field of view into multiple channels. The multiple channels are dispersed into multiple spectral signatures and observed on a two-dimensional focal plane array in real time. The entire hyperspectral datacube is collected simultaneously.
Type:
Grant
Filed:
June 6, 2007
Date of Patent:
July 31, 2012
Assignee:
Bodkin Design & Engineering LLC
Inventors:
Andrew Bodkin, Andrew I. Sheinis, Adam Norton
Abstract: An herbal preparation comprised of sage, thyme and cumin is found to relieve the symptoms of inflammation and smooth muscle contraction. The preparation preferably comprises sage, thyme and cumin in the proportions 0.50, 0.43 and 0.07 respectively. The symptoms of menstrual cramps and asthma are relieved by administration of the preparation.
Abstract: This disclosure relates to the synthesis of Er doped GaN epilayers by in-situ doping by metal-organic chemical vapor deposition (MOCVD). In an embodiment, both above and below bandgap excitation results in a sharp PL emission peak at 1.54 ?m. Contrary with other growth methods, MOCVD grown Er-doped GaN epilayers exhibit virtually no visible emission lines, an present a small thermal quenching effect. The Er incorporation has very little effect on the electrical conductivity of the GaN epilayers and Er doped layers retain similar electrical properties as those of undoped GaN.
Type:
Grant
Filed:
August 24, 2007
Date of Patent:
July 24, 2012
Inventors:
Hongxing Jiang, Jingyu Lin, Cris Ugolini, John Zavada
Abstract: A system generates FIR laser radiation. An electron source generates an electron beam. A grating horn interacts with the electron beam to produce the FIR laser radiation. The grating horn may comprise a flat base and a pair of grating elements attached to the base, each of the grating elements being ruled with a grating period, the grating elements oriented in phase and in substantial symmetry about a normal to the flat base.
Abstract: A self-retaining artificial spinal disc is formed of a flexible material and has a peripheral lip or meniscus extending from its top and/or bottom surface. The meniscus/menisci encircle portions of vertebrae adjacent the implant site, to enhance retention of the artificial spinal disc when seated in the spinal column. The meniscus/menisci for example snugly overlie the vertebral portions, and foster a suction seal between the disc and the adjacent vertebrae. The disc may be formed as an integral whole, or as two half-discs joinable by gluing, melting or like methods. In a related method, a self-retaining artificial spinal disc is formed in layers, by pouring and drying measures of liquid disc solution in a mold. A meniscal extension is formed from the disc body. Drugs or salts may be added to the disc layers, for example to provide an artificial spinal disc with time-release antibiotics or a desired porosity.
Abstract: An image sensor apparatus is disclosed. The image sensor apparatus includes an image sensor for generating pixel data corresponding to a scene under a scene illuminant and a processor. The processor includes an illuminant estimation module for receiving a subset of the pixel data associated with a subset of a color space and finding a chromaticity trend in the pixel data subset to estimate the scene illuminant. A white balance and color correction module in the processor applies white balance and color correction coefficients to the pixel data according to the estimated scene illuminant.
Abstract: A leak detection system for a flowing electrolyte battery comprising a containment member associated with at least one of a stack of a flowing electrolyte battery and an electrolyte reservoir of a flowing electrolyte battery and a sensing member for sensing a fluid leak within the containment member.