Abstract: The present invention relates to approaches, methods, pharmaceuticals and uses directed to the curative treating or preventing of Primary Progressive Multiple Sclerosis (PP-MS), by using 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone (Idebenone) as the active agent.

Abstract: A method of session processing in the Internet Protocol (IP) Multimedia Subsystem (IMS) comprises: Interrogating-Call State Control Function (I-CSCF) accessing the Home Subscriber Server (HSS) to query the registration location of the called user, the I-CSCF sending the Session Initiation Protocol (SIP) request to the Serving-Call State Control Function (S-CSCF) based on the response of the HSS; when the response time of the S-CSCF to the SIP request sent from the I-CSCF has expired, the I-CSCF re-selecting the S-CSCF, and sending the SIP request to the S-CSCF. And an Interrogating-Call State Control Function is provided. According to the present invention, if the S-CSCF returned by the HSS to process the unregistered service of the IMS user does not responded because of the device failure or communication interruption or the like, the I-CSCF can re-select other S-CSCF to process the unregistered service of the IMS user, so as to improve the quality of service and to increase the satisfaction of user.

Abstract: A storage method, a storage system, and a controller are disclosed. The method is applicable to a system that includes at least one controller, at least two Peripheral Component Interconnection Express (PCIE) Input/Output (IO) modules, and at least two storage devices. The at least two storage devices are connected through a PCIE switch chip of the at least one controller, and the at least two PCIE IO modules are connected through a PCIE switch chip of the at least one controller. The method includes: receiving a request message from a server through the at least two PCIE IO modules; and accessing the at least two storage devices according to the request message. The at least two PCIE IO modules are shared between controllers, thereby saving resources; and the storage devices access the controllers without the need of a hard disk controller or a hard disk extension chip, thereby saving costs.

Abstract: Filtration systems may comprise a manifold having a fitting and a filter having a fitting. One of the manifold fitting and the filter fitting may comprise a nozzle including a tip portion having a contact surface. The other of the manifold fitting and the filter fitting may comprise a receptacle which receives the nozzle and has a contact surface. The filter may be removably mountable to the manifold with the filter fitting detachably engaging the manifold fitting and the contact surface at the tip portion of the nozzle abutting and sealing against the contact surface of the receptacle to prevent leakage at the end of the nozzle.

Abstract: In a method for controlling an internal combustion engine with direct fuel injection, an injection parameter is determined in dependence on a temperature of the internal combustion engine. The method is characterized in that a first value of the internal combustion engine temperature is determined which, in the event of changes in the operating point of the internal combustion engine, changes comparatively quickly to a value which is characteristic of the new operating point. A second value of the internal combustion engine temperature is formed which, in the event of changes in the operating point, changes comparatively slowly, and in that the injection parameter is defined in dependence on the first value and the second value.

Abstract: A method for transmitting additional information in a satellite navigation system includes providing a navigation message including a continuous data stream having a prescribed bit rate and structuring the navigation message in a plurality of pages generated according to a prescribed page definition so as to transmit information, wherein each of the plurality of pages includes a checksum calculated as a function of information contained in the page. The method further includes generating at least one new page containing the additional information so as to form a changed, navigation message according to a further page definition that differs from the prescribed page definition such that the checksum calculated as a function of information contained on the page generated according to the prescribed page definition is false; and transmitting the at least one new page.

Abstract: A coding method, a decoding method, a coder, and a decoder are disclosed herein. A coding method includes: obtaining the pulse distribution, on a track, of the pulses to be encoded on the track; determining a distribution identifier for identifying the pulse distribution according to the pulse distribution; and generating a coding index that includes the distribution identifier. A decoding method includes: receiving a coding index; obtaining a distribution identifier from the coding index, wherein the distribution identifier is configured to identify the pulse distribution, on a track, of the pulses to be encoded on the track; determining the pulse distribution, on a track, of all the pulses to be encoded on the track according to the distribution identifier; and reconstructing the pulse order on the track according to the pulse distribution.

Abstract: A transportable device for colonizing and harvesting invertebrate animals in proximity to a floor of a body of water includes at least two quadrangular frames, each of which include a trapping surface. A central hinge is disposed between opposing, inner traverse sides of the at least two quadrangular frames and has a first one-way folding direction. Two secondary hinges are disposed on opposite sides of the central hinge, each of the secondary hinges having a second one-way folding direction that is opposite to the first one-way folding direction such that the at least two quadrangular frames have an opening angle with respect to each other that is adaptable to a structure of the floor of the body of water.

Abstract: The present invention provides processes for producing isoquinolinium compounds, and for converting them into cisatracurium salts, e.g.

Abstract: A robot control system has a connection module for a data network and includes a filter module configured to read data out of a data flow of a data network. The filter module identifies real-time data in the data network and extracts the real-time data as required. In addition, a method for directing data traffic in real time between a data system based on real-time and a network includes the steps of monitoring a data flow in the network for defined data using a filter module in the data system, extracting the defined data from the network, identifying real-time data in the defined data using an identification characteristic, and relaying the real-time data to a first receiving module.

Abstract: A dispersion compensation method and a dispersion compensation device in an optical communication system are provided. The method mainly includes the following steps. A dispersion compensation value transmitted through a working path at a second wavelength is received through a non-working path at a first wavelength in an optical communication system. The non-working path at the first wavelength and the working path at the second wavelength use the same service channel. Dispersion in the non-working path at the first wavelength is compensated according to the dispersion compensation value. Therefore, no matter the working path is a main path or a backup path, the dispersion compensation value on the non-working path can be accurately regulated in time, such that the dispersion of the working path reaches an optimal status each time after the protection switching occurs to the service, thereby ensuring the fast switching of the service.

Abstract: An electrostatic spraying assembly including a housing and a plurality of elongated electrode elements supported within the housing each defining a respective fluid passageway. An electrode header connectable to a high voltage source is supported within the housing in spaced relation to the electrode elements for charging the electrodes to an electrical potential by induction, and in turn, charging liquid directed through the passageways. The electrode header and a resilient valve element supported thereon are movable between retracted and closing positions for controlling the flow of fluid through the electrode passageways for discharge into an electrical field generated by an induction element supported in spaced relation to the discharge ends of the electrode elements.

Abstract: A method and system for recovering from service failure, and the method includes: sending, by a failure detecting node of a cross-domain connection service, a CALL_ID (Call Identifier) that identifies the cross-domain connection service and information on a disabled link in the cross-domain connection service to a first node of the cross-domain connection service, and performing, by the first node of the cross-domain connection service, an end-to-end connection recovery on a corresponding cross-domain connection service according to the CALL_ID and the information on the disabled link. According to the invention the end-to-end connection recovery of the cross-domain connection service can be implemented and the viability of the cross-domain connection service can be improved.

Abstract: An optical blood monitoring system with a ratiometric model determines hematocrit values for a hemodialysis patient, from which hemoglobin values for the patient are estimated. The ratiometric model is calibrated, normally against a cell counter, using blood from a blood bank. The blood from a blood bank is preserved in a long term preservative which is typically different than that found in clinical settings. The hematocrit value determined by the ratiometric model is scaled by scaling factor so that the estimated hemoglobin level output from the monitor consistently matches that measured in a clinical setting. The hematocrit scaling factor is substantially about 1.033 when the patient's blood sample is stored in a short term preservative ethylene diamine tetra acetic, and is substantially about 1.06 when the hematocrit is measured in the blood sample without preservative being added to the blood sample. The hemoglobin value can also be adjusted for altitude.

Abstract: Disclosed are methods of preparing a macromolecular conjugated ligand and a metal complex thereof. The metal complex is targeted for use as a contrast agent, for example, in MRI. The method of preparing a macromolecular conjugated ligand comprises: (a) providing a compound of formula (I) wherein R, A, and Pg are as defined herein, (b) reacting the compound of formula (I) with a macromolecular compound (e.g., dendrimer) in an organic solvent medium which is substantially free of water to obtain a macromolecular conjugated compound, and (c) removing the carboxyl-protecting groups to obtain a carboxyl-deprotected macromolecular conjugated compound. The metal complex can be prepared by reacting the carboxyl-deprotected macromolecular conjugated compound with an ion (e.g., Gd(III)). Also disclosed are two carboxyl-protected 1B4M-DTPA intermediate compounds.

Abstract: An upright vacuum cleaner for cleaning a surface includes a base unit, a carriage configured to move the base unit on the surface, and an upper body having a dust collection container disposed therein. The upper body is supported so as to be tiltable relative to the base unit and is lockable in a parked position in which the vacuum cleaner has a substantially upright position when standing on the surface. A motor-fan unit is configured to provide a partial vacuum at the surface. An air conduit connecting the base unit and the dust collection container includes an interface and a section formed by a hose or an assembly of the hose and a wand. The section is connected downstream of the interface and is disposed at least partially externally on the upper body. The section is configured to enable a vacuuming mode of operation that is independent of the base unit. A tubular member forming at least part of a transition between the hose and the upper body. The tubular member is swivelably disposed on the upper body.

Abstract: The present invention relates to voriconazole, processes of preparing voriconazole, and pharmaceutical compositions and therapeutic uses thereof. In particular, the present invention also relates to voriconazole prepared from voriconazole having a substantially undefined shape and/or crystal habit. The invention further relates to voriconazole having a modified sphericity factor and/or specific surface area and/or Sauter diameter compared to voriconazole known from the prior art.

Abstract: A substrate for detecting samples includes; a body, and a plurality of micro lenses arranged on the body and configured for attachment to at least one sample, wherein the at least one sample emits fluorescent light, and wherein the plurality of micro lenses condense the fluorescent light emitted from the at least one sample via refraction.

Abstract: The invention is directed to a cell comprising a nucleic acid encoding an Activation Induced Deaminase (AID) polypeptide, a fusion protein comprising an AID polypeptide, and methods of using a nucleic acid encoding an AID polypeptide.

Abstract: An image stabilization device includes a number of micromechanical actuators, an image recording sensor, and a computational device. The image sense generates image data of an image and is suspendedly mounted to the micromechanical actuators. The computational device receives and processes the image data generated by the image recording sensor. The computational device includes a detection device for detecting shake so as to perform an image analysis on the image data and detect changes in a time sequence of the image data. The detected changes are used to generate control signals for controlling the micromechanical actuators so as to mechanically move the image recording sensor in a manner to counteract the shake and to stabilize the image.