Patents Represented by Attorney M.-E. M. Timbers
  • Patent number: 4929754
    Abstract: The invention relates to new benzenesulphonamidoindanyl compounds useful in the treatment and prophylaxis of thromboembolic diseases, arteriosclerosis and tumor metastasis.
    Type: Grant
    Filed: February 1, 1989
    Date of Patent: May 29, 1990
    Assignee: Dr. Karl Thomae GmbH
    Inventors: Josef Nickl, Armin Heckel, Erich Muller, Berthold Narr, Johannes Weisenberger, Wolfgang Eisert, Thomas Muller
  • Patent number: 4929727
    Abstract: The invention relates to an improved process for precipitating cytosine from an aqueous solution of an alkali or alkaline earth metal salt of cytosine using sulfuric acid.
    Type: Grant
    Filed: August 25, 1989
    Date of Patent: May 29, 1990
    Assignee: Boehringer Ingelheim KG
    Inventors: Georg Hilgers, Joachim Hess
  • Patent number: 4886814
    Abstract: Substituted thiazoles, oxazoles and 2-hydroxy morpholine compounds useful in the treatment of diabetes mellitus and obesity are described.
    Type: Grant
    Filed: September 4, 1987
    Date of Patent: December 12, 1989
    Assignee: Dr. Karl Thomas GmbH
    Inventors: Manfred Reiffen, Rudolf Hurnaus, Robert Sauter, Wolfgang Grell, Eckhard Rupprecht
  • Patent number: 4851408
    Abstract: The use of 6-allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine and the pharmacological acid addition salts thereof for the release of growth hormone.
    Type: Grant
    Filed: December 10, 1987
    Date of Patent: July 25, 1989
    Assignee: Boehringer Ingelheim KG
    Inventor: Victor Brantl
  • Patent number: 4640913
    Abstract: Phosphocholine derivatives and compositions are described which are useful as hypotensive agents and in the treatment of hypertension in warm-blooded animals.
    Type: Grant
    Filed: January 10, 1983
    Date of Patent: February 3, 1987
    Assignee: American Cyanamid Company
    Inventors: Allan Wissner, Robert E. Schaub, Phaik E. Sum
  • Patent number: 4628046
    Abstract: This disclosure describes a new antibacterial agent designated LL-C23201.delta., produced in a microbiological fermentation under controlled conditions using a new strain of Streptomyces olivaceo-griseus, sp. nov. and mutants thereof. This new antibacterial agent is active against a variety of microorganisms and thus is useful in inhibiting the growth of such bacteria wherever they may be found.
    Type: Grant
    Filed: June 20, 1983
    Date of Patent: December 9, 1986
    Assignee: American Cyanamid Company
    Inventors: David P. Labeda, Joseph J. Goodman, John H. E. J. Martin, deceased
  • Patent number: 4610822
    Abstract: Improved process for the preparation of 6-substituted penicillanic acids, in particular 6[D(-)-.alpha.-(4-alkyl-2,3-dioxo-]-piperazinocarbonylamino)phenylacetamid o]penicillanic acids, and the pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: March 12, 1982
    Date of Patent: September 9, 1986
    Assignee: American Cyanamid Company
    Inventors: Donald C. Boop, Karel F. Bernady
  • Patent number: 4585760
    Abstract: Dimethyfurano analogs of daunomycin are described, including (.+-.)-8.alpha.-acetyl-6,7,8,9-tetrahydro-5,6.beta.,8.beta.,10-tetrahydrox y-1,3-dimethyl-anthra[2,3-c]-furan-4,11-dione-6-(3-amino-2,3-6-trideoxy-.al pha.-L-lyxo-hexopyranoside), which are useful in the treatment of cancer in mammals, such as melanoma, squamous cell, myeloma and pranceatic.
    Type: Grant
    Filed: July 16, 1981
    Date of Patent: April 29, 1986
    Assignee: American Cyanamid Company
    Inventor: Ving J. Lee
  • Patent number: 4568685
    Abstract: N-[(1H-1,2,4-Triazol-l-yl)alkyl]arylamides which are inhibitors of thromboxane synthetase enzyme.
    Type: Grant
    Filed: February 29, 1984
    Date of Patent: February 4, 1986
    Assignee: American Cyanamid Company
    Inventors: William B. Wright, Jr., Jeffery B. Press, Andrew S. Tomcufcik
  • Patent number: 4544665
    Abstract: This invention concerns 1-aryl-3-azabicyclo[3.2.0]heptanes and their acid-addition salts. More particularly, this invention pertains to compositions useful for treatment of depression in warm-blooded animals.
    Type: Grant
    Filed: November 21, 1983
    Date of Patent: October 1, 1985
    Assignee: American Cyanamid Company
    Inventors: Joseph W. Epstein, Thomas C. McKenzie, William J. Fanshawe
  • Patent number: 4535180
    Abstract: This disclosure describes 11-deoxy-11-substituted members of the E.sub.2, F.sub.2, E.sub.1, F.sub.1, dihydro E.sub.1 and dihydro F.sub.1 prostaglandin series which are useful as hypotensive agents and as anti-ulcer agents.
    Type: Grant
    Filed: July 30, 1981
    Date of Patent: August 13, 1985
    Assignee: American Cyanamid Company
    Inventors: Charles V. Grudzinskas, Martin J. Weiss
  • Patent number: 4496549
    Abstract: This invention relates to a novel method for the treatment of malarial infections in warm-blooded animals using the antibiotics X-14868A, LL-C23024 beta, LL-C23024 iota, and combinations theory and to compositions containing these antibiotics.
    Type: Grant
    Filed: January 17, 1983
    Date of Patent: January 29, 1985
    Assignee: American Cyanamid Company
    Inventor: Arnold L. Oronsky
  • Patent number: D280556
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: September 10, 1985
    Assignee: American Cyanamid Company
    Inventor: Eric M. Mittleberg
  • Patent number: D280557
    Type: Grant
    Filed: September 26, 1983
    Date of Patent: September 10, 1985
    Assignee: American Cyanamid Company
    Inventor: Douglas C. Becker
  • Patent number: D285533
    Type: Grant
    Filed: March 12, 1984
    Date of Patent: September 9, 1986
    Assignee: American Cyanamid Company
    Inventors: Andrew J. Berish, Thomas J. Kokoska