Abstract: Materials and methods useful for generating highly mannosylated pseudotyped lentiviral vector particles comprising a Vpx protein are provided. More specifically, methods for generating such materials include culturing in a culture medium including kifunensine a virus packaging cell with a lentiviral vector genome including a polynucleotide encoding an exogenous antigen, a polynucleotide encoding a Sindbis E2 glycoprotein that preferentially binds dendritic cells expressing DC-SIGN, and a polynucleotide encoding a Vpx protein or a Vpr protein that retains SAMHD1-inhibiting activity, followed by isolating a pseudotyped lentiviral vector particle that preferentially binds dendritic cells expressing DC-SIGN.

Abstract: The invention relates to novel strains of Lactobacillus helveticus. More specifically, the invention relates to strains of Lactobacillus helveticus having a lactose-negative phenotype and to the uses thereof in the agri-food industry. The invention also relates to a method for obtaining such strains of Lactobacillus helveticus.

Abstract: An inspection apparatus for optically examining bottles, having a mirror cabinet for imaging different circumferential side views of a bottle to be examined. The deflection mirrors for beam paths associated with lateral image areas are tilted such that an image distortion caused by central projection will be compensated for in the lateral image areas.

Abstract: A method for forming a fuse of a semiconductor device includes performing an ion-implanting process at sides of a fuse blowing region of a metal fuse, thereby increasing the concentration of impurity ions of a thermal transmission path region. In a subsequent laser blowing process, as a result of the increased resistance of metal fuse the electric and thermal conductivity is reduced, thereby increasing the thermal condensation efficiency of the fuse blowing region and improving the efficiency of the laser blowing process.

Abstract: A gas pressure regulator comprises a main body having a first, gas inlet pipe and a second, gas outlet pipe, a calibrated gas passage through which gas flows from the first pipe to the second pipe, a shutter housed at least partially in the main body and mobile lengthwise along a first defined line to adjust the opening of the calibrated passage, a device for actuating the shutter and a regulator spring unit opposing the movement of the shutter.

Abstract: The present invention discloses a method, an apparatus, and a system for IKE negotiation. One method comprises: upon receiving a data packet, selecting one of multiple service cards according to a pre-configured policy and triggering the service card to send an IKE negotiation packet; and saving the mapping between the IKE negotiation packet and the service card. The other method comprises: upon receiving an IKE negotiation packet, selecting one of multiple service cards according to a pre-configured policy, triggering the service card to perform IKE negotiation, and saving the mapping between of the IKE negotiation packet and the service card. The solution enables a network node a node to distribute IKE negotiations to different service cards to perform IKE negotiation at the same time, improving IKE negotiation speed.

Abstract: A method of adaptively scheduling communications in a wireless mesh network including a plurality of network nodes includes generating a network routing scheme based on a topology of the wireless mesh network, generating a communication schedule for the wireless mesh network, and automatically updating the communication schedule in response to detecting a change in a transmission requirement of at least one of the plurality of network nodes. The act of generating a communication schedule includes defining a communication timeslot of a predefined duration and defining a plurality of superframes as repeating cycles of a certain number of consecutively scheduled communication timeslots.

Abstract: A method and an apparatus for processing a prescription order are described herein. A prescription label for the prescription order may be generated in response to receipt of the prescription order. The prescription label being generated in a priority order based on a plurality of pharmacy factors. The prescription order may be filled according to the priority order based on the plurality of pharmacy factors. Based on the prescription label, a plurality of graphic displays may be generated to verify the prescription order. The patient may be notified of the status of the prescription associated with the prescription order based on the plurality of graphic displays.

Abstract: Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus.

Abstract: The compositions, articles and methods described herein remain intact for sealing between and around structures that contact salt water. The compositions include: (i) a partially cross-linked polyacrylamide/partially neutralized polyacrylic acid copolymer; (ii) a smectite clay; (iii) an elastomer, e.g., butyl rubber; (iv) a polyolefin polymer or copolymer; and (v) a cationic flocculant, the compositions have exceptional and unexpected free swell and cohesiveness when in contact with high conductivity water or multivalent ion-containing-contaminated water. The articles of manufacture described herein all include a combination of (i) a partially cross-linked acrylamide/acrylate/acrylic acid copolymer; (ii) a smectite clay; (iii) an elastomer, e.g.

Abstract: In a method of forming patterns of a semiconductor device, a semiconductor substrate defining photoresist patterns formed over a target etch layer is provided. An auxiliary layer is formed over the semiconductor substrate and the photoresist patterns. The auxiliary layer formed on a surface of the photoresist patterns is denatured into first auxiliary patterns. A photoresist film is formed over the semiconductor substrate, the first auxiliary patterns, and the auxiliary layer. The auxiliary layer formed below the photoresist film is denatured into a second auxiliary pattern. Here, the auxiliary layer remains only between the photoresist patterns. Etch mask patterns, including the photoresist patterns and the auxiliary layer, are formed by removing the photoresist film and the first and second auxiliary patterns.

Abstract: Light emitting devices are described which incorporate, as the light emitting element, a dendrimer of which the constituent dendrons include a conjugated dendritic structure comprising aryl and/or heteroaryl groups connected to each other via bonds between sp2 hybridised ring atoms of said aryl or heteroaryl groups.

Abstract: A method of potentiating the activity of a therapeutic drug, like a chemotherapeutic drug or an antibiotic, in a cell or tissue, by inhibiting the efflux capability of a multidrug transporter are disclosed. The method is useful in the treatment of a cancer by sensitizing tumor cells to a chemotherapeutic agent. Compounds capable of inhibiting an efflux capability of a multidrug transporter also are disclosed.

Abstract: The present invention relates to methods involving avoiding adverse drug interactions with fluvoxamine and pirfenidone or other moderate to strong inhibitors of CYP enzymes.

Abstract: Patterns of a nonvolatile memory device include a semiconductor substrate that defines active regions extending in a longitudinal direction, an isolation structure formed between the active regions, a tunnel insulating layer formed on the active regions, a charge trap layer formed on the tunnel insulating layer, a first dielectric layer formed on the charge trap layer and the isolation structure, wherein the first dielectric layers is extended along a lateral direction, a control gate layer formed on the first dielectric layer, wherein the control gate layer is extended along the lateral direction, and a second dielectric layer formed on a sidewall of the control gate layer along the lateral direction and coupled to the first dielectric layer.

Abstract: A method of forming gate patterns of a nonvolatile memory device comprises forming stack patterns each having an insulating layer and a conductive layer stacked over a semiconductor substrate, and forming an anti-oxidation layer on sidewalls of the insulating layer by selectively nitrifying the insulating layer.

Abstract: Belt reversing mechanisms configured to reverse a belt at an upstream portion and a downstream portion of a return belt of a belt conveyor, includes two sets of pinch rollers spaced apart from each other in a belt movement direction and configured to support the belt, and two sets of guide roller mechanisms spaced apart from each other in the belt movement direction and are configured to guide the belt in a tubular shape from outside between the pinch rollers such that the belt is reversed 180 degrees and twisted to cause a center portion of a span between the pinch rollers so as to form a tubular open cross-section with a dirty surface facing inward; and the belt between the two sets of pinch rollers forms a catenary curve or a curve close to the catenary curve.

Abstract: A biostimulation apparatus of the present invention includes a laser oscillator for oscillating an ultra short pulsed laser beam and an optical system for focusing the ultra short pulsed laser beam, wherein the ultra short pulsed laser beam is focused by the optical system at a target portion of a living subject to cause the target portion to be irradiated with the laser beam to stimulate an acupuncture point, and wherein the target portion is either the acupuncture point or its periphery.

Abstract: Embodiments of a switched reluctance (SR) motor for use in a integrated vacuum system for a vehicle are disclosed. The SR motor may receive input voltage directly from an electrical storage device used to start up an engine of the vehicle. The SR motor may include an encoder that triggers an optical sensor to provide signals to a motor controller. The motor controller may energize stator poles based on the received signals. The encoder may be mechanically phase-advanced with respect to poles of the rotor to ensure proper start-up of the SR motor. Commutations of the motor may occur before a point of maximum inductance where the rotor and stator are aligned. In a preferred embodiment, the input voltage received by the SR motor is in a range of 9-16 Volts DC, a maximum drawn current is 36 amps, and the phase advance is between 9-11 degrees.