Abstract: In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a microscope, determining volumetric imaging parameters, directing at least two photons into a region of interest, scanning the region of interest across a portion of the tissue, imaging a plurality of layers of the tissue in a plurality of volumes of the tissue in the region of interest, sectioning the portion of the tissue and imaging a second plurality of layers of the tissue in a second plurality of volumes of the tissue in the region of interest, detecting a fluorescence image of the tissue due to said excitation light; and processing three-dimensional data that is collected to create a three-dimensional image of the region of interest.

Abstract: Perfluoroisopropyl-substituted perfluorophtalocyanines, including zinc (II), copper (II) and oxo-vanadium (IV) complexes of 29H,31H,1,4,8,11,15,18,22,25-octakis-fluoro-2,3,9,10,16,17,23,24-octakis-perfluoro(isopropyl)phthalocyanine (F64Pc), may be sublimed under high vacuum conditions. The compounds/molecules produce advantageous thin films (20-100 nm) on glass substrates by physical vapor deposition. Many potential applications of the disclosed compounds/molecules are disclosed, e.g., as semiconductor materials. In situ electrical conduction and optical transmission measurements during the deposition process reveal the formation of conducting pathways and potential microscopic intermolecular electronic couplings.

Abstract: An apparatus for storing fluid and dispensing multiple portions of the stored fluid has a container defining a variable-volume storage chamber; a dispensing valve including a valve inlet coupled in fluid communication with the variable-volume storage chamber, and an elastic valve member in fluid communication with the valve inlet and defining a normally-closed valve opening; a manually engageable actuator; and a pump including a compressible member defining a compression chamber coupled in fluid communication with the variable-volume storage chamber. Multiple portions of the stored fluid are hermetically sealed in the variable-volume storage chamber. The actuator is manually engageable and movable between (i) a first position wherein the compression chamber defines a first volume, and (ii) a second position wherein the compression chamber defines a second volume less than the first volume.

Abstract: The present invention relates to an ultrasound imaging system in which the scan head either includes a beamformer circuit that performs far field subarray beamforming or includes a sparse array selecting circuit that actuates selected elements. When used with second stage beamforming system, three dimensional ultrasound images can be generated.

Abstract: A functional unit for a microprocessor is provided, which allows for fast, parallel data read, write, and manipulation operations in the microprocessor that are useful for a number of software applications, such as cryptography. The functional unit includes first and second source registers for receiving first and second data items to be processed by the functional unit, first and second banks of memory tables, a combinational logic circuit, and a decoder. The first and second banks of memory tables are in communication with the first source register, and each of the tables is indexed by an index comprising a portion of the first data item received by the first source register. Each index points to a lookup result in a respective one of the memory tables.

Abstract: Device and method for needle penetrating and filling a chamber with a predetermined substance, and hermetically resealing a resulting needle hole in the device by applying radiation thereto. The needle penetrable and resealable portion defines a predetermined wall thickness in an axial direction thereof, and may include a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and resealable portion during penetration by and withdrawal of the needle. Such thermoplastic may include a predetermined amount of pigment that allows the thermoplastic to substantially absorb laser radiation at a predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period.

Abstract: Medical diagnostic instruments and systems are provided that include (i) a proximal handle configured and dimensioned to permit an operator to manually grasp the instrument; (ii) an ultrasound probe including a longitudinal shaft extending distally from the handle and terminating in a distal end, and an ultrasound transducer mounted with respect to the longitudinal shaft proximate the distal end thereof, the ultrasound transducer including an array of ultrasonic energy generation elements; and (iii) a tactile feeler probe mounted with respect to the ultrasound probe, the tactile feeler probe including a longitudinal shaft mounted with respect to the longitudinal shaft of the ultrasound probe and extending distally beyond the distal end thereof, and a feeler probe tip (e.g., a ball tip) defined at a distal end of the longitudinal shaft of the tactile feeler probe. Advantageous methods for use of the disclosed instruments and systems are also provided, e.g.

Abstract: This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.

Abstract: The present invention provides a method and composition are provided that includes an ion exchange resin treated with from between about 0.01 to about 10 percent by weight of one or more sugar alcohols in contact with one or more ionic pharmaceutically active drug.

Abstract: Advantageous apparatus, are provided for facilitating maintenance of a automated pool cleaning device. More particularly, an improved automated pool cleaning device is provided, according to the present disclosure. The device, generally, includes a facially accessible quick-release roller assembly, a bucket-type filter assembly, and a windowed top access lid assembly. The improved roller assembly and filter assembly are easily accessible for maintenance purposes. Furthermore, the windowed lid assembly provides visual feedback as to when the filter assembly needs to be cleaned.

Abstract: A disposable liquid absorbing cleaning pad for a mop includes a layer of sponge material, a layer of flexible open cell foam material made from melamine resin fixedly attached to the layer of sponge material and attachment structure secured to the layer of sponge material for removably attaching the cleaning pad to the mop. In using the cleaning pad, the layer of flexible open cell foam material made from melamine resin is the layer that contacts the surface to be cleaned. The cleaning pad may be provided with a suitable attachment structure for mounting the pad onto a butterfly mop, a squeeze mop or a roller mop.

Abstract: A key box construction, wherein a shaft of a door is provided with two parallel flat surfaces in axial extensions of the shaft, an outer cover is provided with bearing parts which each comprise a groove having the same width between parallel flat surfaces of the groove as the width between the two parallel flat surfaces of each axial extension and at an angle. The door is provided at the lower end portion thereof with hooks, whereby the door is hooked directly on an inner case by the hooks and a latch.

Abstract: An apparatus for measuring a spatially under-sampled Bidirectional Reflectance Distribution Function (BRDF) of a surface. The apparatus may comprise a first light source directed to illuminate the surface from a first illumination direction, and a plurality of sensors positioned to receive light reflected by the surface. The plurality of sensors may comprise first, second and third sensors positioned to receive light reflected by the surface in first, second and third non-coplanar directions. In various embodiments, the apparatus may also comprise a computer in communication with the plurality of sensors. The computer is configured to convert light sensed by the plurality of sensors into a first appearance property of the surface considering the first, second, and third reflectance directions. A method of calculating xDNA, the vector sum of the observed reflectance intensity over a plurality of wavelengths and angles. Methods of using the calculated xDNA for formulating recipes for a surfaces colors.

Abstract: A print data generation apparatus generates print data to be used for printing a print result including a plurality of lines on a tape-shaped print medium. The print data generation apparatus includes an input device that inputs a plurality of character strings for the plurality of lines to be printed on the print medium, a storage device that stores the plurality of character strings for the plurality of lines, and a print data generation device that generates the print data in which each of the plurality of character strings are repeatedly arranged in a predetermined character size defined for each of the plurality of lines and at predetermined spacing in each of the plurality of lines until the print result reaches a predetermined length.

Abstract: A sewing machine includes a needle bar to which an engraving needle is attached and is capable of executing an engraving process of forming an engraved pattern on a workpiece. The sewing machine further includes a heightwise position adjusting mechanism adjusting a mounting heightwise position of the engraving needle relative to the needle bar, a unit imaging the engraved marks formed on the workpiece by the engraving needle, thereby obtaining an image of each engraved mark, a detection unit extracting a region of each engraved mark from the image to detect a size of each engraved mark, a determination unit comparing the size of each engraved mark with a reference value stored, determining a mounting heightwise position of the engraving needle, and a unit informing of information for adjusting the mounting heightwise position of the engraving needle according to determination made by the determination unit.

Abstract: A wobble joint fitting for a vehicle seat has a first joint arm, which carries an internal gear and forms a first bearing surface, which are central to a main axis, and a second joint arm to which an eccentric gear is allocated, which comprises an externally toothed pinion and a second bearing surface. The pinion and the second bearing surface are central to an eccentric axis. An eccentric driving part is disposed in the area between the first bearing surface and the second bearing surface. Clamping parts, in a clamping state, displace the eccentric axis relative to the main axis. The eccentric driving part defines the eccentric. The rotary drive of the eccentric driving part causes a rotation of the pinion relative to the internal gear even without the clamping parts being present, wherein only play compensation is not obtained without the presence of the clamping parts.

Abstract: An orally adminsterable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a pharmaceutical active compound, aminosalicylic acid or a pharmaceutically tolerable salt or a derivative thereof.

Abstract: A 2-acylaminothiazole derivative or a pharmaceutically acceptable salt thereof having an excellent effect of proliferating human c-mpl-Ba/F3 cells and an activity of increasing platelets based on the effect of promoting the formation of megakaryocytic colonies. A compound or a pharmaceutically acceptable salt thereof useful in treating thrombocytopenia.

Abstract: A printer includes a connection device that connects to an external device, a printing device that prints a character on a print medium, an input device that inputs the character and an instruction, and a first data acquisition device that acquires first data created in the external device via the connection device. The printer further includes a print history storage device that stores print history information of the first data and a second data used for printing by the printing device among the first data acquired by the first data acquisition device and the second data created based on the character and the instruction inputted by the input device. The printer also includes a print control device that causes the printing device to perform printing based on the print history information stored in the print history storage device.