Abstract: The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
Type:
Grant
Filed:
January 6, 2003
Date of Patent:
November 8, 2005
Assignees:
Elan Pharmaceuticals, Inc., Pharmacia & Upjohn Company
Inventors:
Martha A. Warpehoski, Barbara Jagodzinska