Patents Represented by Law Firm Millen, Raptes & White
  • Patent number: 3994050
    Abstract: A fastening clip for mounting paintings and the like which comprises a piece of spring material, having two substantially opposing pincers which are adapted for clamping something between them, a connecting part extending from the first pincer to the second pincer and including a spring loop, which extends from the second pincer, with the feature that the spring loop is extended in a general direction substantially orthogonal to an imaginary plane in which the pincers move towards and away from each other. Preferably the spring loop is located on one side of the imaginary plane in which the pincers move and a remainder of the connecting part is located on the other side of the imaginary plane so as to lead to one pincer located with regard to the other pincer in such a way that springing open of the spring loop moves the pincers towards one another.The spring clip can be of narrow width, in which case one or more can be clipped onto each edge of a picture or the like.
    Type: Grant
    Filed: June 20, 1975
    Date of Patent: November 30, 1976
    Inventor: Hans Werner Alfred Bub
  • Patent number: 3995023
    Abstract: Improved allergen-containing extracts are obtained by the extraction of allergy-causing materials, such as pollen and house dust, with hydrophilic aqueous extractants, by pretreating the allergen-containing material with a lipophilic, aqueous extraction liquid. Allergens extracted in the two steps can be combined and formed onto allergen preparations, which can be used both for diagnostic and therapeutic purposes.
    Type: Grant
    Filed: December 15, 1975
    Date of Patent: November 30, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Otto Nieschulz, Gunther Rudiger, Jurgen Maass
  • Patent number: 3994937
    Abstract: 15.alpha.,16.alpha.-METHYLENE-4-ESTREN-17.beta.-OLS OF THE Formula ##SPC1##Wherein R.sub.1 is lower alkyl, R.sub.2 is hydrogen or an acyl residue, R.sub.3 is hydrogen or a substituted or unsubstituted, saturated or unsaturated monovalent lower aliphatic hydrocarbon, and X is oxygen or the group H,OR.sub.4, wherein R.sub.4 is hydrogen or an acyl residue, have useful anabolic, androgenic, and/or gestagenic activity.
    Type: Grant
    Filed: June 28, 1974
    Date of Patent: November 30, 1976
    Assignee: Schering Aktiengesellschaft
    Inventors: Rudolf Wiechert, Hermann Steinbeck, Walter Elger
  • Patent number: 3993759
    Abstract: 2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is used as an anthelmintic against cestodes and trematodes, preferably in admixture with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: March 11, 1974
    Date of Patent: November 23, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rolf Pohlke, Friedrich Loebich, Herbert Thomas, Jurgen Thyssen
  • Patent number: 3992891
    Abstract: In a process for recovering the energy from a liquefied gas by evaporation in heat exchange with a cycle medium which is simultaneously cooled, said cycle medium being thereafter compressed, heated, subjected to engine expansion and recovered in a cyclical manner, wherein the improvement comprises operating the cycle so that the cycle medium remains in the gaseous phase throughout the entire cycle.
    Type: Grant
    Filed: February 18, 1975
    Date of Patent: November 23, 1976
    Assignee: Linde Aktiengesellschaft
    Inventor: Anton Pocrnja
  • Patent number: 3993760
    Abstract: (-)-2-Benzoyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline is prepared by benzoylation of (-)-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline, or cyclization of a compound of the formula ##SPC1##Wherein X is F, Cl, Br, I or O-tosyl and which has the optical configuration of the final product, or cyclization of a compound of the formula ##SPC2## wherein Y is OH, alkoxy, F, Cl, Br or I under HY-removing reaction conditions and which has the optical configuration of the final product, which is an anthelmintic.
    Type: Grant
    Filed: June 21, 1974
    Date of Patent: November 23, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rolf Pohlke, Friedrich Loebich, Jurgen Seubert, Herbert Thomas, Peter Andrews
  • Patent number: 3992443
    Abstract: Alcohols, preferably ethoxylated alcohols, are carboxymethylated by reacting a mixture thereof and a salt of chloroacetic acid with an alkali hydroxide.
    Type: Grant
    Filed: April 15, 1975
    Date of Patent: November 16, 1976
    Assignee: Chemische Werke Huls Aktiengesellschaft
    Inventor: Hermann Springmann
  • Patent number: 3991579
    Abstract: A self-advancing chock for supporting the roof of the gallery of a mine near the working face utilizing one or more lever arms articulated to the forward portion of a base (nearer the working face) and to the rear portion of a roof-supporting cap. The cap has sufficient area to cover the other elements of the chock in all positions of the lever arms and may have a slightly concave upper surface. If two lever arms are used they may be rigidly or flexibly interconnected and the cap may be in two sections for use with sloping or irregular roof areas. The base element may also be in two sections.
    Type: Grant
    Filed: December 2, 1974
    Date of Patent: November 16, 1976
    Assignee: Mines de Potasse d'Alsace S.A.
    Inventor: Pierre Deffontaine
  • Patent number: 3992386
    Abstract: Phenoxyacetic acids of the formula ##SPC1##Wherein R.sub.1 is H or alkyl of 1-4 carbon atoms; R.sub.2 is H, or when R.sub.4 is Q, also alkyl of 1-4 carbon atoms; R.sub.3 is methyl, phenyl or chlorophenyl; and R.sub.4 is piperidino, isoindolino, 1,2,3,4-tetrahydroquinolino, 1-R.sub.5 -1,2,3,4-tetrahydro-4-quinolyl, 4-piperidinophenyl, 4-piperidinophenoxy, 1-pyrryl, or Q, wherein R.sub.5 is H or alkyl of 1-4 carbon atoms; and Q is 4-oxo-1,2,3,4-tetrahydroquinolino, 4-hydroxy-1,2,3,4-tetrahydroquinolino, 4-chromanyl, 4-thiochromanyl or 1-phenyl-1,2,3,4-tetrahydro-4-quinolyl; and the salts thereof, possess cholesterol level-lowering activity.
    Type: Grant
    Filed: March 8, 1974
    Date of Patent: November 16, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Erich Schacht, Werner Mehrhof, Herbert Nowak, Zdenek Simane, Detlev Kayser
  • Patent number: 3992468
    Abstract: Process for hydrodealkylating alkylaromatic hydrocarbons using a catalyst comprising at least two metals deposited on a carrier, a first of these two metals being selected either from the group consisting of cobalt, ruthenium, osmium, palladium, rhodium, iridium and platinum or from the group consisting of chromium, molybdenum, tungsten and manganese, and the second of these two metals being selected from zinc, cadmium, gallium, indium, thallium, manganese, copper, silver, gold, yttrium, titanium, niobium, tentalum, chromium, molybdenum, tungsten, rhenium, germanium, tin and lead.
    Type: Grant
    Filed: February 24, 1975
    Date of Patent: November 16, 1976
    Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres Elf
    Inventors: Jean Cosyns, Bernard Juguin, Jean-Francois Le Page, Jean Miquel
  • Patent number: 3992465
    Abstract: Process for producing aromatic hydrocarbons, particularly benzene and/or toluene from a feed charge containing saturated and unsaturated hydrocarbons, by catalytic treatment of said charge with hydrogen, fractionation of the resulting product to separate a fraction containing benzene and/or toluene, extractive distillation of at least one aromatic hydrocarbon in a column, by means of an extraction solvent from which said hydrocarbon is subsequently separated, and recycling to the reaction zone of at least one portion of the products recovered at the top of said extractive distillation column and containing essentially C.sub.6 and C.sub.7 saturated hydrocarbons.
    Type: Grant
    Filed: January 2, 1974
    Date of Patent: November 16, 1976
    Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrolieres Elf
    Inventors: Bernard Juguin, Georges Cohen, Paul Mikitenko
  • Patent number: 3992374
    Abstract: Amino-substituted nitroimidazolyl-methyleneaminoimidazolidinones of the formula ##SPC1##Wherein --NR.sub.2 R.sub.3 is dialkylamino or heterocyclic amino, and the physiologically acceptable salts thereof, possess antitrichomonial activity.
    Type: Grant
    Filed: June 28, 1974
    Date of Patent: November 16, 1976
    Assignee: Schering Aktiengesellschaft
    Inventors: Clemens Rufer, Hans-Joachim Kessler
  • Patent number: 3990963
    Abstract: Used lubricating oils are first heated to 200.degree.-500.degree. C, optionally with added steam, and then filtered through a membrane such as an ultra-filtration membrane. The latter has preferably a cut range of from 5,000 to 300,000.
    Type: Grant
    Filed: February 28, 1975
    Date of Patent: November 9, 1976
    Assignee: Institut Francais du Petrole, des Carburants et Lubrifiants et Entreprise de Recherches et d'Activities Petrollieres Elf
    Inventors: Francois Audibert, Maurice Born, Daniel Defives, Xavier Marze
  • Patent number: 3990956
    Abstract: A process for the preparation of keto steroids by electrochemical reduction, comprising electrolyzing a .alpha.,.beta.-unsaturated keto steroid in a nonaqueous nitrogen-containing solvent containing an electrolyte which is at least one of:A. a quaternary ammonium salt of the general formula NR.sub.1 R.sub.2 R.sub.3 R.sub.4 X, wherein R.sub.1.sub.+4 represent an alkyl, aryl, or aralkyl residue, orB. an alkali or alkaline earth salt of X, wherein X is sufficient anion for charge equalization and represents halogen, tetrafluoborate, sulfate, perchlorate, alcoholate, arylsulfonate or alkylsulfonate.
    Type: Grant
    Filed: January 14, 1975
    Date of Patent: November 9, 1976
    Assignee: Schering Aktiengesellschaft
    Inventor: Klaus Junghans
  • Patent number: 3989833
    Abstract: Adenine derivatives of the formula ##SPC1##Wherein R is phenyl or thienyl, and the physiologically acceptable acid addition salts thereof, possess, with good compatibility, cardio-active properties and are produced by the reaction of a purine derivative of the formula ##SPC2##Wherein X is F, Cl, Br, I, SR.sub.1, SOR.sub.1, SO.sub.2 R.sub.1 or OSi(CH.sub.3).sub.3, R.sub.1 being alkyl of 1-4 carbon atoms, phenyl or benzyl, with an amine of the formula ##SPC3##Wherein R has the values given above, or a salt thereof.
    Type: Grant
    Filed: November 4, 1974
    Date of Patent: November 2, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Rochus Jonas, Werner Mehrhof, Karl Heinz Becker, Hans-Jochen Schliep
  • Patent number: 3989818
    Abstract: Influenza virus is purified, fractionated or concentrated in an aqueous medium, using a linear filamentary non-charged polymer, preferably polyethylene glycol, as an insolubilising agent, at a concentration not exceeding 5% by weight. Impurities and large virus particles can be fractionated off at PEG concentrations of say up to 1%. Phase separation is achieved most readily when assisted by ultra-centrifugation at low temperature between 0.degree. and 6.degree. C. Precipitation of the virus from dispersions of comparatively high concentration (say 600 HA units or more per ml.) results in intimately aggregated virus particles, which are easier to further purify, and which result in an improved vaccine. Novel concenrates of globular influenza virus are also described.
    Type: Grant
    Filed: October 4, 1974
    Date of Patent: November 2, 1976
    Assignee: South African Inventions Development Corporation
    Inventor: Alfred Polson
  • Patent number: 3988468
    Abstract: 7-Methoxy-6-thiatetracyclines of the formula ##SPC1##Wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each are H or alkyl of 1 to 4 carbon atoms, and the physiologically acceptable acid addition salts thereof.
    Type: Grant
    Filed: July 30, 1975
    Date of Patent: October 26, 1976
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Werner Rogalski, Richard Kirchlechner, Juergen Seubert, Rudolf Gottschlich, Walter Hameister, Rolf Bergmann, Helmut Wahlig
  • Patent number: 3986841
    Abstract: Apparatus for the continuous production of saturated aliphatic dicarboxylic acids by the catalyzed nitric acid oxidation of the corresponding cycloalkanols and cycloalkanones with recirculation of the reaction sludge and the reaction gases, which comprises cooling the reaction sludge by passing it through the tubes of a multiple tube heat exchanger, separating the reaction gases downstream of the heat exchanger, and dispersing the recycled portion of the reaction gases in the reaction sludge upstream of the heat exchanger, in a volume amount 0.1 to 2.0 times the volume of the reaction sludge circulating per unit time and in a pressure ratio of initial gas pressure to pressure in the circulation reactor at the gas feed point of (x + 0.25) : x to (x + 1.5) : x, wherein x is the pressure at the gas feed point, to form a homogeneously dispersed three-phase mixture of the recycled reaction gases in the reaction sludge in the tubes of the heat exchanger.
    Type: Grant
    Filed: January 29, 1975
    Date of Patent: October 19, 1976
    Assignee: Chemische Werke Huls Aktiengesellschaft
    Inventors: Gerhard Hellemanns, Hermann Rohl, Peter Hegenberg, Werner Eversmann
  • Patent number: 3987099
    Abstract: A process for the catalytic hydrogenation of dodecanedioic acid dinitrile to the corresponding primary amine employing a hydrogenation catalyst which comprises 5-35% by weight of at least one of catalytically active cobalt and nickel as the active component supported on one or more oxides of aluminum, silicon, titanium and iron, wherein the specific surface area of the support material is 0.01-1.2m.sup.2 /g., the pore volume is 0.05-0.4 ml./g., the annealing loss is less than 0.1% and the extractable alkalinity of the support is 0.08-20% by weight of the support. Sufficient alkali is present in the hydrogenation diluent to ensure that the desired alkali concentration remains on the catalyst surface, thereby extending the useful life of the catalyst.
    Type: Grant
    Filed: October 22, 1974
    Date of Patent: October 19, 1976
    Assignee: Chemische Werke Huls Aktiengesellschaft
    Inventors: Gunter Hockele, Gerhard Ludwig
  • Patent number: 3987159
    Abstract: Stable preparations of sensitized erythrocytes are provided by simultaneously admixing washed erythrocytes in a buffered aqueous solution of glutaraldehyde, antigen or antigen-protein conjugate and formaldehyde. After washing, the separated sensitized erythrocytes can be lyophilized and thereby become stable at room temperature.
    Type: Grant
    Filed: March 1, 1974
    Date of Patent: October 19, 1976
    Assignee: Schering Aktiengesellschaft
    Inventors: Jurgen Spona, Michael Topert