Abstract: The present invention relates to mechanically hemostatic body-absorbable compositions having a putty-like consistency. The compositions preferably comprise a finely powdered, carboxylic acid salt and a liquid block copolymer of ethylene oxide and propylene oxide.

Abstract: The invention proposes a system for authenticating and authorizing network services comprising: a mobile device being adapted to, upon receipt of an information message indicating at least one network access type, determine the network access type, to create a start message containing at least a user identity, and to encapsulate the start message in an authentication message compatible with the access network identified in the information message, and an access controller for reading the encapsulated message from the mobile and forwarding the encapsulated message to an authentication server identified in the encapsulated message. The invention also proposes a corresponding method for authenticating and authorizing network services, and an access control device, a subscriber device and a router device.

Abstract: A coil device is provided having a member adapted to extend around and conform to an outer surface of a subject and a conductor adapted to extend only once around a first portion of the subject. The coil device can be positioned about the subject in order to measure a volume of the subject. When placed about the subject in the presence of a relatively homogeneous magnetic field, the conductor can generate a signal indicative of a volume of the first portion of the subject. The coil device may also include two or more conductors separately generating signals indicating volumes of two or more corresponding portions of the subject. In some cases the coil device includes associated authorization data that can limit use of the coil device. Systems and methods incorporating the coil device are also provided.

Abstract: Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier.

Abstract: Disclosed is a portable fluid dispensing device for infusing a fluid into the body of a user and/or for sensing an analyte within the body. The device includes at least one housing to retain a source of energy to energize the device, the source of energy comprising at least one electrochemical cell to produce electrical energy upon exposure of the cell to air, and a seal to prevent exposure of the at least one cell to air when the source of energy is not in use and to enable exposure of the at least one cell to air prior to energizing the device with the source of energy. The at least one housing includes an opening to provide access to the seal to enable actuation of the seal to control exposure of the at least one cell to air.

Abstract: The present invention relates to a receptacle which comprises a generally elongate tubular body, a plurality of pellets of a predetermined size and shape containing a predetermined measure of active ingredient and filtration means disposed at or adjacent each end of the tubular body to retain the pellets substantially within the body. The receptacle is sized to allow a carrier liquid to be drawn through it. The passage of the carrier liquid through the receptacle causes the pellets to progressively dissolve, thereby releasing the active ingredient into the beverage upon consumption.

Abstract: A system, method and computer program product is presented for versioning a business process model. The business process model is decomposed into a number of artifacts. A hierarchical dependency graph is generated for the number of artifacts to produce, for each artifact, a set of referencing artifacts and a set of referenced artifacts. The set of referenced artifacts are compiled by creating a runtime format and computing a unique version identifier for each referenced artifacts, and the unique version identifier for each referenced artifact is incorporated into a version identifier of each associated referencing artifact from the set of referencing artifacts. At least one of the referenced artifacts is modified to produce a new version of the associated referencing artifact.

Abstract: The invention provides hard coat and image receiving layer structures and related methods used in ID document production. These structures and methods provide ID documents that offer hard protection in areas where needed (e.g., in optical windows for machine readable data), and also provide image receiving layers for later printing of variable data, such as personalization information of the bearer. Implementations of the structure provide an effective interface between hard coat and image receiving layers that provides enhanced durability in manufacture and field use.

Abstract: A computer-implemented method of distributing information retrieved from one or more data repositories includes: invoking a producer method to generate a document using data retrieved from one or more data repositories; invoking a converter method to convert the generated document to an output format; and invoking a distributor method to distribute the converted document through a distribution channel. The methods may be implemented in a framework that allows flexible implementation of one or more additional methods. The methods may belong to respective producer, converter and distributor classes.

Abstract: A medication container encoding, verification and identification method is provided that includes receiving data characterizing a medication, generating an identifier encapsulating the data and applying an identifier to a medication container such that it is automatically readable by a medication administration device and/or a medication wasting device. Related apparatus, systems, methods and articles are also described.

Abstract: The invention provides human monoclonal antibodies or fragments thereof, that specifically bind to CXCR4. Disclosed are methods of use of such antibodies for the treatment and/or prevention of a CXCR4 disease or disorder such as cancer and X4-tropic HIV-1 infection Also provided are methods of use of such antibodies and antibody fragments for the treatment or prevention of cancer metastasis. The invention provides methods of mobilizing CD34+stem cells from the bone marrow and methods of blocking chemotaxis of CXCR4-expressing cells in response to SDF-1. Also provided are methods of use of the antibodies and fragments thereof for the prevention or treatment of graft-versus-host disease. Finally, the invention provides methods of inhibiting new tumor blood vessel formation and/or tumor cell angiogenesis.

Abstract: A compound for use in the treatment or prophylaxis of viral infections such, for example as chicken pox or shingles caused by the Varicella Zoster virus, said compound having the general formula (II): wherein X is O, S, NH or CH2, Y is O, S or NH, Z is O, S or CH2, R1 is C1-6 alkyl, preferably n-alkyl, e.g., n-pentyl or n-hexyl, and one of R2 and R3 is OH, and the other of R3 and R2 is a neutral, non-polar amino acid moiety, or a pharmaceutically acceptable salt or hydrate thereof. Said neutral, non-polar amino acid moiety R2 or R3 may be (IV): in which R4, R5, R6 and R7 are each independently H or C1-2 alkyl. In preferred embodiments, one of R2 or R3 is valine, leucine, isoleucine or alanine, particularly valine.

Abstract: A computer-implemented method and system for automated entity identification for efficient profiling in an event probability prediction system. A first subset of entities belonging to one or more entity classes is defined. At least one historical profile is constructed for each entity in the subset of entities based on a set of possible outcomes of transaction behavior of each entity in the first subset of entities. Based on the historical profiles, a second subset of entities having transaction behavior associated with a transaction is selected, the transaction behavior being predictive of at least one targeted outcome from the set of possible outcomes. The first subset of entities is redefined with the second subset of entities.

Abstract: The present invention relates to substituted [1,2,4]triazolo-[4,3-a]pyrazine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted [1,2,4]triazolo-[4,3-a]pyrazine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.

Abstract: The present invention provides novel peptide immunogens comprising influenza virus matrix 2 protein epitopes and related compositions and methods. The present invention relates to a composition comprising a peptide immunogen useful for the prevention and treatment of an influenza virus-mediated disease. The invention also relates to vaccines, immunogenic products and immunogenic compositions containing the peptide immunogens.

Abstract: A coil device is provided having a member adapted to extend around and conform to an outer surface of a subject and a conductor adapted to extend only once around a first portion of the subject. The coil device cats be positioned about the subject in order to measure a volume of the subject. When placed about the subject in the presence of a relatively homogeneous magnetic field, the conductor can generate a signal indicative of a volume of the first portion of the subject. The coil device may also include two or more conductors separately generating signals indicating volumes of two or more corresponding portions of the subject. In sonic cases the coil device includes associated authorization data that can limit use of the coil device. Systems and methods incorporating the coil device are also provided.

Abstract: A computer readable storage medium comprises executable instructions to provide a workspace for a user to define an expression with expression components from a graphical palette associated with the workspace. Placeholders are indicated in the workspace for the expression components to be added by the user. The placeholders are associated with a data type. The data type is enforced for each placeholder. A structured visual representation of the expression is provided on the workspace.

Abstract: Disclosed herein are stabilized weapon mount systems that allow a gunner (i.e. operator of a weapon) to mount and operate a standard weapon in a manner similar to a stand-alone weapon while compensating for the motion of the platform. The system includes an aiming gimbal that is movable by an operator during stabilization into an aiming orientation directed toward a target and a stabilization gimbal nested within the aiming gimbal and adapted to securely couple to a weapon. The stabilization gimbal and aiming gimbal are mechanically coupled by a control unit such that the stabilization gimbal is moved by the control unit and the aiming gimbal is not moved by the control unit. A stabilization device automatically commands the control unit to move the stabilization gimbal relative to the aiming gimbal using the motors to correct for the base movement and maintain the aiming orientation directed toward the target.

Abstract: A noise reduction system for attachment to a pillow having a top surface is disclosed, wherein a head of a user can be configured to be placed on the top surface of the pillow. The system includes a plurality of support bands, each having a distal end and a proximate end, wherein the distal end of each of the plurality of support bands is configured to be coupled to the pillow and a pad configured to be coupled to each proximate end of each of the plurality of support bands. Upon coupling of the distal end of each of the plurality of support bands to the pillow, the pad is configured to be disposed above the top surface of the pillow at a predetermined height. The head of the user is configured to be placed between the top surface of the pillow and the pad, wherein the pad is configured to cover an ear of the user to reduce noise perceived by the ear of the user.

Abstract: The present invention relates to processes for the preparation of biaryl oxazolidinones. These compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.