Abstract: The invention relates to molecules having Formula (100): wherein ————— represents a bond present or absent; Ar is a substituted or unsubstituted benzene or pyridine ring; V is a C or N atom, and W, X, Y and Z together form a 2,4-thiazolidinedione, 2-thioxo-4-thiazolidinedione, isoxazolidinedione, 2,4-imidazolidinedione, [1,2,4]-oxadiazolidine-3,5-dione or 2-thioxo-4-imidazolidinedione residue; or a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
March 8, 2002
Date of Patent:
September 4, 2007
Assignees:
Incyte San Diego Inc., Ortho McNeil Pharmaceutical Inc.
Abstract: A system and method for transmitting multiple data streams from a host to a printing device. Data streams are arranged according to color, segmented and compressed, if desired. If compression is used, each segment may compressed with a different compression algorithm. Each segment contains a header describing the size of the data in the segment. The host transmits a print header containing information and instructions necessary for the print device to reassemble and process the data segments to produce a printed item.
Type:
Grant
Filed:
March 21, 2001
Date of Patent:
September 4, 2007
Assignee:
Lexmark International Inc.
Inventors:
Heather Laudan Clark, Duane Edward Norris
Abstract: This invention is based on the problem of achieving the most planar possible phase boundary extending in the horizontal direction between the still molten material and the material that has already crystallized out in a vertical Bridgman crystal-growing furnace or vertical gradient freeze crystal-growing furnace for crystallizing out the semiconductor melt and doing so at a low cost. Therefore, jacket heaters are provided coaxially with the furnace core containing the crucible and measurement devices for determining radial temperature differences in the space between the jacket heaters and the crucible, whereby the heat output of the jacket heaters is adjusted so that the measured temperature differences become zero. Thus, at least in the planes in which the measurement devices are located, radial heat transport is prevented and a phase boundary that is not curved is implemented.
Abstract: A non-toxic environmentally friendly aqueous disinfectant is disclosed for specific use as prevention against contamination by potentially pathogenic bacteria and virus. The aqueous disinfectant is formulated by electrolytically generating silver ions in water in combination with a citric acid. The aqueous disinfectant may include a suitable alcohol and/or a detergent. The aqueous disinfectant has been shown to be very effective at eliminating standard indicator organisms such as staphylococcus aureus, salmonella cholerasuis and pseudomonas aeruginosa.
Abstract: A light fixture or troffer for directing light emitted from a light source toward an area to be illuminated, including a reflector assembly within which the light source is positioned and a lens assembly detachably secured to a portion of the reflector assembly such that a lens of the lens assembly overlies the light source and such that substantially all of the light emitted from the light source passes through the lens assembly. In one example, the lens includes a curved prismatic surface that can be oriented toward or away from the underlying light source.
Type:
Grant
Filed:
October 21, 2004
Date of Patent:
August 28, 2007
Assignee:
Acuity Brands, Inc.
Inventors:
Carl T. Gould, John T. Mayfield, III, Gary D. Trott, Christopher L. Sharp
Abstract: The invention relates to producing a melt that is as homogeneous as possible, to which fresh material in the form of granulate is continuously supplied. Since the granulate is cooler than the melt, heat sinks form that are especially pronounced when the granulate forms clumps in the melt. Therefore, the invention relates to a means for distributing the granulate. In one aspect, the means are inductors arranged outside the melting crucible that generate an alternating magnetic field in the melt. In this way, electrical currents are induced there that, in turn, cause the material flows. In one aspect, the inductors are arranged and controlled in such a way that a rapid distribution of the granulate is effected and thus its rapid melting. In this way, good homogeneity is achieved, especially in the center of the melt where the removal of the melted material also occurs.
Type:
Grant
Filed:
August 26, 2004
Date of Patent:
August 28, 2007
Assignee:
Crystal Growing Systems GmbH
Inventors:
Andreas Mühe, Burkhard Altekrüger, Axel Vonhoff
Abstract: A system for producing an ultrasound image comprises a scan head having a transducer capable of generating ultrasound energy at a frequency of at least 20 megahertz (MHz), and a processor for receiving ultrasound energy and for generating an ultrasound image at a frame rate of at least 15 frames per second (fps).
Type:
Grant
Filed:
October 10, 2003
Date of Patent:
August 14, 2007
Assignee:
VisualSonics Inc.
Inventors:
James I. Mehi, Nicholas Christopher Chaggares, Stuart Foster, Robert McConaghy
Abstract: The present invention provides isolated polypeptides of human p53 that contain mutations. These mutations can be toxic mutations, supertransactivating mutations or tox-suppressor mutations. Further provided by the invention are methods of identifying toxic, supertransactivating, weak transactivating and tox-suppressor mutations as well as methods of identifying compounds that mimic the toxic, supertransactivating and tox-suppressor mutations in human p53. Also provided are methods of inducing toxicity in a cell by administering a polypeptide comprising a supertransactivating or a toxic mutation.
Type:
Grant
Filed:
July 28, 2000
Date of Patent:
August 14, 2007
Assignee:
The United States of America, as represented by the Secretary, Dept. of Health and Human Services, NIH
Abstract: A person can use a portable electronic device to electronically purchase or otherwise request a product, service or other deliverable related to audio programming to which the person is listening at the time they initiate the request. The request is fulfilled by a service that analyzes the audio content to identify the deliverable the person desires.
Type:
Grant
Filed:
November 14, 2000
Date of Patent:
August 14, 2007
Assignee:
Radiant Systems, Inc.
Inventors:
Michael C. Finley, Michael Dudgeon, Lehman Zellosis Smith, IV, John Wade, David Griffin, David Edward McCaw, Jr., James Lee Fortuna
Abstract: A photodetector and method of detecting far infrared optical signals. In one embodiment of the present invention, the photodetctor has a plurality of N barriers, N being an integer greater than 1, each barrier being a layer of a material made from a first and a second group III elements and a first group V element and characterized by a bandgap. The photodetector further has a plurality of N?1 emitters, each emitter being a layer of material made from a third group III element and a second group V element and characterized by a bandgap different from that of the barriers and having at least one free carrier responsive to optical signals, wherein each emitter is located between two barriers so as to form a heterojunction at each interface between an emitter and a barrier.
Type:
Grant
Filed:
October 16, 2001
Date of Patent:
August 7, 2007
Assignee:
Georgia State University Research Foundation, Inc.
Abstract: Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used successfully to produce a hitherto unknown type of human Platelet-Derived Growth Factor (PDGF) receptor protein free of other PDGF receptors. These proteins can be produced from DNA segments in cells in various functional forms. These forms variously enable biochemical and functional studies of these novel receptors as well as production of antibodies. Means are described for determining the level of expression of genes for specific types of PDGF receptor proteins, for example, by measuring mRNA in cells with PDGF receptor type-specific DNA probes or by measuring antigen in biological samples with type-specific antibodies.
Type:
Grant
Filed:
November 3, 2003
Date of Patent:
August 7, 2007
Assignee:
United States of America, as represented by the Secretary, Dept of Health & Human Services
Inventors:
Toshimitsu Matsui, Stuart A. Aaronson, Jacalyn H. Pierce
Abstract: A rolling bracket assembly for use in transporting loads of various size and shape. The rolling bracket assembly comprises at least one base assembly. The base assembly is adapted for engagement with at least a portion of an underside of a skid and comprises a wheel assembly adapted to ambulate the load being transported. The bracket assembly may also comprise two base assemblies connected by an elongate connector.
Abstract: A process for the co-precipitation of a substance with a stabilizer therefor, by a gas anti solvent process comprising introducing into a particle formation vessel a supercritical fluid pure or mixed with a modifier; and a solution comprising said substance and said stabilizer dissolved in a solvent; so as said solvent is extracted from the solution by said supercritical fluid and co-precipitation of the substance and stabilizer occurs. The process may be carried out using an apparatus, for example, shown in FIG. 1, comprising a particle formation vessel (22) and a nozzle (27) having a central orifice (39) serving to introduce a solution of the substance and a plurality of outer orifices (41) serving to carry a flow of supercritical fluid into the particle formation vessel (22), such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron sized particles of the substance/stabilizer occurs.
Type:
Grant
Filed:
October 21, 2002
Date of Patent:
July 31, 2007
Assignee:
Dompé pha.r.ma S.p.A.
Inventors:
Marco Gentile, Cesare Di Palma, Maria Candida Cesta
Abstract: A hammermill having a housing, a rotor assembly, a plurality of hammers, and an attrition plate assembly is provided to reduce oversized particulate material to a desired size. The housing defines an enclosed work space. The rotor assembly is disposed within the housing for rotation about a longitudinal axis of the housing. The plurality of hammers is coupled to the rotor assembly and is disposed within the enclosed work space. Each hammer having an impact end, a connection portion adapted to couple to a portion of the rotor assembly, and a shank portion extending between the impact end and the connection portion.
Abstract: A decorated floor panel having a core with a top surface and an opposite bottom surface; a decorative layer coupled to the top surface of the core, the decorative layer having a desired aesthetic appearance; and a wear layer coupled to and substantially covering the decorative layer for protecting the decorative layer. The wear layer has an exposed wear surface with depressions therein of a variable depth below the wear surface, the depressions being arranged to display a desired texture pattern. It is noted that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to ascertain quickly the subject matter of the technical disclosure. The abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims pursuant to 37 C.F.R. § 1.72(b).
Abstract: The present invention provides methods for the incorporation of sulfonate functional groups onto the surface of carbonaceous compounds and materials, and similarly provides several surface modified carbonaceous compounds and materials resulting therefrom.