Abstract: Disclosed herein are indolo[3,2-c]quinoline compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein R and m are given the definitions as set forth in the Specification and Claims. These compounds can be used to inhibit both growth of cancer cells and activity of telomerase.

Abstract: A system includes an objective lens, an imaging module, and a measurement module. The objective lens is configured to receive light emitted by a light source, focus the emitted light onto a target object, and receive light reflected by the target object. The imaging module is configured to receive a first portion of the reflected light. The measurement module is configured to receive a second portion of the reflected light and includes a photo detector and an astigmatic lens configured to direct the second beam onto the photo detector.

Abstract: An apparatus for engaging in wireless commercial transactions includes a mobile phone equipped with a dedicated actuator for initiating a commercial transaction, and an optical input for receiving information concerning prices of goods; a network hub for wireless exchange information between a commercial establishment and said mobile phone within the boundaries of the establishment; and a financial/authorization institution for associating a PIN number with said mobile phone and for authorizing transactions initiated by said mobile phone.

Abstract: Compounds of formula (I) especially where R1 is an optionally substituted alkyl, aralkyl or heterocyclyl-alkyl group, are shown to have activity as sodium channel blockers or as antifolates. Some novel compounds where R1 is an aralkyl or heterocyclyl-alkyl are disclosed.

Abstract: Immunogenic compositions, cancer vaccines and methods for treating cancer are provided. Compositions comprising: (a) a glycan such as Globo H or an immunogenic fragment thereof, wherein the glycan is conjugated with a carrier protein by a linker such as para-nitrophenyl; and (b) an adjuvant comprising glycolipid capable of binding CD1d on a dendritic cell, such as an ?-galactosyl-ceramide derivative, wherein the immunogenic composition induces an immune response that induces a higher relative level of IgG isotype antibodies as compared to IgM isotype antibodies, are provided. Immunogenic compositions comprising the carrier protein diphtheria toxin cross-reacting material 197 (DT-CRM197) and the adjuvant C34 are provided. Antibodies generated by immunogenic compositions disclosed herein further neutralize at least one of the antigens Globo H, stage-specific embryonic antigen-3 (SSEA-3) and stage-specific embryonic antigen-4 (SSEA-4).

Abstract: A stamp for patterning onto a receiving surface of an object (101) according to a defined pattern (P) comprises a stamping surface (21) of a resilient diaphragm (20). The stamping surface is planar at rest. The pattern is reproduced on the stamping surface and the diaphragm is affixed to a rigid body (13) along a peripheral edge, so that a middle part of the diaphragm can move along a direction perpendicular to the stamping surface. The diaphragm (20) is more flexible near the peripheral edge than in the middle part. Then, the pattern (P) printed on a pseudo-spherical receiving surface (103) using the stamp exhibits few distortion.

Abstract: A curved multi-layer structure (10) is formed from individual films (1, 2) that are initially flat. The films are firmly bonded to each other along respective facing surfaces. A heat treatment is applied to one or both of the films (1, 2) of the structure so as to cause respective contractions or elongations that are different for the two films at standard use temperatures. A difference between said contractions or elongations causes the curvature of the multi-layer structure. The structure thus has a permanent curved shape, without contact between compression-forming instruments and a useful part of the multi-layer structure being necessary. The multi-layer structure can then be applied onto a curved substrate without causing any tears or ripples.

Abstract: Under one aspect, a laminated, spliced superconductor wire includes a superconductor joint, which includes (i) first and second superconductor wires, each wire including a substrate, a superconductor layer overlying the substrate, and a cap layer overlying the superconductor layer; and (ii) a conductive bridge, the conductive bridge including a substrate, a superconductor layer overlying the substrate, and a cap layer overlying the superconductor layer, wherein the cap layer of the conductive bridge is in electrically conductive contact with a portion of the cap layer of each of the first and second superconductor wires through an electrically conductive bonding material. The spliced wire also includes (b) a stabilizer structure surrounding at least a portion of the superconductor joint, wherein the superconductor joint is in electrical contact with the stabilizer structure; and (c) a substantially nonporous electrically conductive filler, wherein the filler substantially surrounds the superconductor joint.

Abstract: A method using a frame structure which supports relay for wireless transmission, which divides the time slots of a sub-frame into some zones, in which the data is transmitted using the manner of TDD, wherein further including that at least one time slot in a sub-frame is set as a hybrid zone; the transmission of the data is realized through frequency division multiplexing the access link and relay link in the hybrid zone of the sub-frame; and also the multi-hop relay is supported under the two work manners of relay in sub-frame and relay in frame.

Abstract: The invention relates to a catheter port for supplying an active substance to an active site which is distant from the port. According to the invention, the housing (1) of the port is designed to have two parts, an upper housing part (7) and a lower housing part (6). The upper housing part (7) holds an insertion part (10) in a clamping manner in a housing recess (8) of the lower housing part (6), wherein a chamber (11) is arranged in said insertion part for receiving the active substance with the interpositioning of a punctured membrane (17) that can be pierced with an injection cannula. While the insertion part (10) and the chamber (11) can be manufactured from a material resistant to the active substance, preferably a heavier ceramics, the upper and lower housing parts may consist of a lighter biocompatible plastic material. It is advantageous that the patient only comes into contact with the upper and lower housing parts made of a biocompatible plastic material and not with the insertion part.

Abstract: Provided are an organic semiconductor compound using thiazole, and an organic thin film transistor having an organic semiconductor layer formed of the organic semiconductor compound using thiazole. The novel organic semiconductor compound including thiazole has liquid crystallinity and excellent thermal stability, and thus is provided to form an organic semiconductor layer in the organic thin film transistor. To this end, a silicon oxide layer is formed on a silicon substrate, and an organic semiconductor layer including thiazole is formed on the silicon oxide layer. In addition, source and drain electrodes are formed on both edge portions of the organic semiconductor layer. The organic thin film transistor using the organic semiconductor layer has an improved on/off ratio and excellent thermal stability. Also, a solution process can be applied in its manufacture.

Abstract: In one aspect, a method includes forming a pit in a top surface of a substrate by removing a portion of the substrate and growing a semiconductor material with a bottom surface on the pit, the semiconductor material different than the material of the substrate. The pit has a base recessed in the top surface of the substrate. In another aspect, a structure includes a substrate having a top surface, the substrate including at least one pit having a base lower than the top surface of the substrate, and a semiconductor material having a bottom surface formed on the base of the pit.

Abstract: A washing machine and a method for manufacturing the same are disclosed. The washing machine includes a tub, a bearing housing having a fastening member and formed by insert-injection molding into the tub so as to expose the fastening member from the tub, and a stator mounted to the fastening member. The washing machine can maintain concentricity of the stator and permit simplification of an assembly process to reduce manufacturing costs.

Abstract: A parabolic trough collector includes a parabolic mirror support structure with a parabolic mirror surface applied thereto, and an absorber support structure supporting an absorber tube. The parabolic mirror support structure and the absorber support structure are mechanically fastened in a fixed position relative to one another on a torsion tube that is arranged below the parabolic mirror surface, and mounted together with the parabolic mirror surface in a fashion capable of rotation about a parabolic trough collector longitudinal rotation axis. The torsion tube is arranged such that the parabolic trough collector longitudinal rotation axis coincides with the central longitudinal axis of the torsion tube.

Abstract: The present application discloses a method for crystallizing sucralose, which uses an alcohol solvent or a mixed solvent of alcohol and other solvent(s) in the crystallization of sucralose.

Abstract: The present invention describes a recombinant construct for detection of halogenated aromatic hydrocarbon compounds. A method for detecting halogenated aromatic hydrocarbon compounds using the recombinant construct is also described.

Abstract: A method for computer-assisted translation from a source language to a target language makes use of number of rules. Each rule forms an association between a representation of a sequence of source language tokens with a corresponding tree-based structure in the target language. The tree-based structure for each of at least some of the rules represents one or more asymmetrical relations within a number of target tokens associated with the tree-based structure and provides an association of the target tokens with the sequence of source language tokens of the rule. An input sequence of source tokens is decoded according to the rules to generate a representation of one or more output sequences of target language tokens. Decoding includes, for each of at least some sub-sequences of the input sequence of source tokens, determining a tree-based structure associated with the sub-sequence according a match to one of the plurality of rules.

Abstract: A power plant for providing electric power to a power grid includes energy sources; power conditioning units and a controller configured to cause power provided to the grid to have selected electrical characteristics. The controller is in high speed real-time communication with the power conditioning units and programmed to provide instructions to the power conditioning units.

Abstract: A method for treating allergy with a pharmaceutical composition containing a detoxified E. coli heat-labile enterotoxin, and, optionally, an allergen.

Abstract: This invention relates to compounds of the following general formula: The variables are defined herein. Also disclosed is a method for treating mucositis or cancer using these compounds.