Abstract: A DNA vaccine effective for inhibiting endothelial cell proliferation comprises a DNA construct operably encoding a vascular endothelial growth factor (VEGF) receptor protein. This invention provides DNA vaccines that encode VEGF receptor-2 (KDR, SEQ ID NO: 2), VEGF receptor-1 (Flt-1, (SEQ ID NO: 4), or Flk-1 (the murine homolog of KDR, SEQ ID NO: 6), DNA sequences SEQ ID NOS: 1, 3, and 5 respectively, as well as methods of using such a DNA vaccine to inhibit vascular endothelial cell proliferation in the tumor micro-environment. Anti-angiogenesis and subsequent decrease in tumor growth and dissemination is achieved.

Abstract: A lighting apparatus includes a lens assembly with mating first and second lens members forming a hollow interior, and an internal assembly including an inner housing. The inner housing is generally triangular-shaped and includes an upper corner, a pair of lower corners and hollow leg portions between the corners. An LED lamp is mounted in the hollow interior of the inner housing, at an upper corner thereof. A circuit board carrying at least one switch is disposed in the hollow leg portion extending between the lower corners of the inner housing, and electrical wiring is disposed in a leg portion, connecting the LED lamp to the circuit board. The base includes a base housing defining a hollow interior and a battery holder received within the hollow interior.

Abstract: A humanized murine antibody is provided. The amino acid sequences of a light chain complementarity determining region from a mouse antibody are grafted onto a human light chain, and a heavy chain complementarity determining region from a mouse antibody are grafted onto a human antibody heavy chain to produce libraries from which a humanized murine antibody having the desired specificity is selected.

Abstract: Improved fabricated subcomponents, components and rotating biological contactor embodiments that are assembled from, and that incorporate, such subcomponents and components are achieved. The components comprise tank sections, bulkheads, contactor drums, paddle wheels, shaft assemblies including associated bearings and supports, each of which may be assembled from preformed subcomponents if desired. Rotating biological contactors are assemblable at an installation site, which may be a confined space if desired, by two men with simple tools. In an assembled rotating biological contactor, the shaft assemblies can rotated by an electric motor, by fluidic pressure exerted upon paddle wheel blades, or by both in combination.

Abstract: Rotating type viscosimeter having a motor (2) for driving a rotating assembly (3) extending through an aperture (4) into a liquid to be tested (1) and measuring the shear forces imparted by said liquid (1) to the rotating assembly (3). In order to prevent said liquid (1) from leaking through the aperture (4) due to a liquid pressure (p1) at the level of the aperture (4), the viscosimeter comprises means for creating a counter-pressure (p2) at the level of a gap between the rotating assembly (3) and the aperture (4). Thanks to this counter-pressure (p2), no solid sealing means are required, thereby improving the durability and the robustness of the viscosimeter, as well as simplifying it by eliminating countermeasures otherwise needed for taking into account parasitic friction forces exerted on the rotating assembly (3) due to such solid sealing means.

Abstract: A cellular structure such as a honeycomb window treatment comprises a plurality of rows of elongated cells secured to one another. Each of the rows is constructed by providing a first longitudinally extending length of material, which includes a first surface and a second surface, as well as, a lesser width portion and a greater width portion. A second length of material is also provided that includes a first surface and a second surface. The second surface of the second material is secured to the first surface over the greater width portion of the first material along a plurality longitudinally extending locations on the second surface of the second material to form a row. A longitudinally extending crease is also formed in the first material such that the lesser width portion and the greater width portion of the first material lie on opposite sides of the crease.

Abstract: Compositions comprising truncated tryptophanyl-tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such tRNA synthetase polypeptides are described. Methods of making and using such compositions are also disclosed.

Abstract: A measurement apparatus includes a speed sensor, a cadence sensor and a display portion. The apparatus further includes a transmit portion for wirelessly transmitting signals detected by the speed sensor and the cadence sensor to the display portion. The transmit portion is provided with a shaft portion extending in one direction, which rotatably supports the cadence sensor and the speed sensor. A measurement body portion including the speed sensor, the cadence sensor and the transmit portion is mounted on chain stay. The display portion is mounted on a portion of a handle in the field of vision of a rider of the bicycle, and it has functions of receiving and processing signals transmitted from the transmit portion, and displaying prescribed information. Thus, the measurement apparatus that can easily be mounted to a bicycle and the sensor apparatus applied thereto are obtained.

Abstract: A collapsible signaling device bearing a pair of opposed message panels is convertible between a display configuration and a compact linear storage configuration. The message panels are joined together at spaced apart points along their periphery using spacers to form a pocket having an internal cavity. A mast is insertable within the pocket and is joined to the panel members at its upper end. A pair of struts of spring material are joined at one end to the upper end of the mast and are joined at their lower ends to a slider member which is slidably movable with respect to the mast. As the slider member is advanced toward the upper end of the mast, the struts are outwardly bowed imparting outwardly directed tension to the periphery of the message panels.

Abstract: A multi-positional swing training device having adjustable configurations suitable for addressing a plurality of swing flaws, such as with a golf swing, is provided. The training device includes a base, and an upright member extending vertically from the base. An elongate arm extends from the upright member and a guide member extends from the distal end of the arm. The position of the arm and guide member relative to the base is adjustable into any variety of positions to address different swing flaws.

Abstract: A rack for holding a bicycle by either its front or back wheel in an upright position on a floor. The rack includes a bracket which is adapted to be fitted on an elongate support frame. A rotatable lower brace extends outwardly from the bracket and includes spaced-apart arms which terminate in a downwardly extending lip. An upper brace extends generally upwardly from the bracket and includes spaced-apart arms. A bicycle is held on the rack by rolling the bicycle wheel directly into the lip of the lower brace and into and between the arms of the upper and lower braces respectively. A plurality of racks can be slidingly fitted onto a single support frame for holding a plurality of bicycles in spaced-apart relationship.

Abstract: There can be obtained a handlebar stem ensuring that a speed indicator provides a readily observable indication and in addition thereto capable of achieving a reduction in size and weight. A handlebar stem attaching a bicycle's handlebar includes a rod attaching the handlebar stem to the bicycle; a speed indicator receiving a signal from a speed sensor to display speed; and an indicator housing located at a front protrusion extending in a forward direction to traverse the rod to house the speed indicator, the indicator housing, as seen along the rod, overlapping or being adjacent to the rod.

Abstract: A combination of a flame arrestor with a reflection suppressor is provided which not only arrests an advancing flame front, but also suppresses or mitigates a reflection wave that is generated by a pressure wave that passes through the combination and continues on to a pipe restriction what generates a reflection wave that proceeds back to the combination. At the combination, the reflection suppressor suppresses and/or mitigates the reflection wave, thereby avoiding a heightened pressure in the combination that could cause a re-ignition and a new flame front and pressure front. The reflection suppressor has a tapered profile that permits a pressure wave to pass along and past the reflection suppressor as it leaves the combination but that impedes and mitigates a returning reflection wave produced by the pressure wave striking a pipe restriction and causing such a returning reflection wave.

Abstract: The self-cleaning enclosed belt conveyor for loose materials comprises a mobile belt (10) operatively connected to proper containment walls (2), where mechanical means (1, 15) are provided for, connected to said conveyor belt (10), wherein said mechanical means perform together with a bottom (8) of said containment walls (2) a recovery operation of the loose materials present in the area between the belt (10), the bottom (8) and said containment walls (2), bringing the materials back either to belt's upper stretch or to adequate containment systems.