Patents Represented by Attorney, Agent or Law Firm Omri M. Behr, Esq.
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Patent number: 6210374Abstract: An inner cylindrical member has a first pair of locking projections on opposite sides of the member at a proximal end and has an extension to which a syringe needle is secured. A second pair of resilient locking projections are spaced from the first pair forming an axially extending locking recess there between at the proximal end. The resilient projections depress to a release position. A pair of finger gripping tabs protrude from the distal end. An outer cylindrical member receives the inner member in its bore. The outer member has an extension which receives the inner member extension and which extensions have mating detents for releasably securing the members in a needle extended use position with the members juxtaposed in nested concentric relation. The outer member at a distal end has projections which mate in the locking recesses at the proximal end to lock the outer member in an extended needle protective position.Type: GrantFiled: April 20, 2000Date of Patent: April 3, 2001Inventor: Robert Malencheck
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Patent number: 6193942Abstract: A catalyst which is capable of decomposing and allaying particularly NOx among other harmful components in the diesel engine exhaust gas and, at the same time, depriving by combustion the exhaust gas of carbonaceous particulates, unburned hydrocarbons, and carbon monoxide and a method for purifying the diesel engine exhaust gas by the use of this catalyst are provided. The catalyst for the decomposition of the nitrogen oxides has a refractory three-dimensional structure coated with a copper-containing zirconia powder having deposited copper and the catalytically active oxide of at least one metal selected from the group consisting of tungsten, gallium, nickel, manganese, iron, and cobalt on a zirconia powder. The method for purifying the diesel engine exhaust gas uses the catalyst.Type: GrantFiled: March 2, 1998Date of Patent: February 27, 2001Assignees: ICT Co., Ltd, International Catalyst Technology, Inc.Inventors: Norimasa Okuda, Makoto Horiuchi
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Patent number: 6194588Abstract: In the production of maleic anhydride by the contact of a raw material gas containing an aliphatic hydrocarbon of not less than 4 carbon atoms and molecular oxygen with a vanadium-phosphorus oxide catalyst, the raw material gas is caused to allow presence therein of nitrogen and an inert gas possessing a thermal conductivity of not less than 800 (10−4Wm−1K−1) at 700 K. The gas formed by the oxidation reaction is allowed to contact an absorbent to effect recovery of the produced maleic anhydride. Maleic anhydride is recovered from produced oxidation reaction gas separated from a remained oxidation reaction gas after recovering maleic anhydride, and the saparated inert gas is circulated to the reaction zone. The catalyst capable of producing maleic anhydride with a high yield can be obtained by activating the vanadium-phosphorus oxide catalyst with the gas composition containing an inert gas possessing a thermal conductivity of not less than 800 (10−4Wm−1K−1) at 700 K.Type: GrantFiled: February 16, 1999Date of Patent: February 27, 2001Assignee: Nippon Shokubai Co., Ltd.Inventors: Osamu Takayasu, Akiyoshi Nakajima, Hideto Hashiba
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Patent number: 6184374Abstract: This invention is in the field of the chemistry of targeting anticancer anthracycline derivatives. More particularly, it concerns doxorubicin (DOX) or its daunosamine modified derivatives (DM-DOX) linked covalently to analogs of peptide hormones such as LH-RH, bombesin and somatostatin. These covalent conjugates are targeted to various tumors bearing receptors for the peptide hormone analogs. The compounds of this invention are represented by General Formula Q14—O—R—P wherein Q has the general formula wherein: Q14 signifies a Q moiety with a side chain at the 14 position, R— is H or —C(O)—(CH2)n—C(O)— and n=0-7, R′ is NH2 or an aromatic, saturated or partially saturated 5 or 6 membered heterocyclic compounds having at least one ring nitrogen and optionally having a butadiene moiety bonded to adjacent carbon atoms of said ring to form a bicyclic system; P is H or a peptide moiety, suitably an LHRH, somatostatin or bombesin analogs.Type: GrantFiled: July 15, 1998Date of Patent: February 6, 2001Assignee: The Administrators of the Tulane Educational FundInventors: Andrew V. Schally, Attila A. Nagy, Ren-Zhi Cai
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Patent number: 6156908Abstract: The invention is directed to a process for the preparation of lactams of Formula I. It is further directed to new advantageous intermediates of Formula II and the use thereof. By the cyclization of compounds of Formula II, compounds of Formula I are obtained.Type: GrantFiled: September 10, 1999Date of Patent: December 5, 2000Assignee: Rohm Gesellschaft, GmbHInventors: Karlheinz Drauz, Ingo Klement, Gunter Knaup
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Patent number: 6151929Abstract: In a device for fastening active components (18) to the bar (6) of a warp knitting machine, the bar (6) has transverse channels (24) each of which is intended to receive a guide section (25) of the active component (18), and a longitudinal groove (20) for receiving holding sections (21) of the active component (18). The longitudinal groove (20) has an uncovered insertion opening area. The transverse channels (24) are arranged next to it. The holding sections (21) are wedged into the longitudinal groove (20) by means of the force of a spring (22). A tool (29) for removing and installing the active components (18) has a first driver (34) carried by an operating handle (31), which driver is fitted to a first stopper (35) on the active component (18) and contributes towards extracting the holding part (21) from the longitudinal groove (20). The result of this is a structure without play, with precise positioning and minimal weight.Type: GrantFiled: November 30, 1999Date of Patent: November 28, 2000Assignee: Karl Mayer Textilmachinenfabrik GmbHInventor: Kresimir Mista
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Patent number: 6146001Abstract: A helium or air filled latex balloon includes a lamp in its interior connected to an external power source by an electrically conductive cable passing through the balloon inlet port and neck. The cable comprises wires encapsulated with Kynar, a polyvinylidene fluoride, a semi-crystalline thermoplastic polymer that exhibits tacky surfaces and excellent properties for providing a weatherproof tight seal between the wire cable and the balloon. The neck is sealed with curling ribbon, by knotting or clips and the like. Air filled balloons may be supported by a stiff music wire or straw and helium filled balloons may be tethered by the cable. A power source illuminates the lamp via the cable.Type: GrantFiled: December 17, 1998Date of Patent: November 14, 2000Assignee: Patrick Alexander, Co., Inc.Inventor: Martin Cwiakala
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Patent number: 6143691Abstract: A purifying catalyst for the exhaust gas from the internal combustion engine of an automobile, for example, is disclosed which excels in the purifying ability in quick response to the atmosphere of the exhaust gas largely varying with changes in the operating condition of the engine involving such phases as idling, acceleration, constant-speed drive, and deceleration. The purifying catalyst contains rhodium, palladium, a cerium compound, and a refractory inorganic oxide as catalytic components carried on a refractory carrier and comprises at least two catalyst layers, namely a catalyst layer containing the cerium compound and a catalyst layer containing palladium.Type: GrantFiled: December 27, 1996Date of Patent: November 7, 2000Assignees: ICT Co., Ltd, International Catalyst Technology, Inc.Inventors: Eiichi Shiraishi, Shigeyoshi Taniguchi, Takeshi Matsumoto
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Patent number: 6114163Abstract: The disclosure relates to a process for obtaining optically active L-.alpha.-aminocarboxylic acids from the corresponding racemic D,L,.alpha.-aminocarboxylic acids. The following steps are involved: (a) the D,L,.alpha.-aminocarboxylic acids are acetylated; (b) the N-acetyl-L-.alpha.-aminocarboxylic acid present in the mixture of N-acetyl-D,L,.alpha.-aminocarboxylic acids thus obtained is broken down enzymatically into the L-.alpha.-aminocarboxylic acid; (c) the L-.alpha.-aminocarboxylic acid is separated from the mixture, a quantity of a solution of N-acetyl-D(L)-.alpha.-aminocarboxylic acids and a quantity of acetate equivalent to the L-.alpha.-aminocarboxylic acid being retained; and (d) the N-acetyl-D(L)-.alpha.-aminocarboxylic acid is racemized and recycled for enzymatic breakdown. Known extraction processes involving steps (a) to (d) have the disadvantage of producing large quantities of salt.Type: GrantFiled: June 16, 1998Date of Patent: September 5, 2000Assignee: Degussa AktiengesellschaftInventors: Karlheinz Drauz, Andreas Bommarius, Michael Karrenbauer, Gunter Knaup
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Patent number: 6110486Abstract: A buccal aerosol spray or capsule using a polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal aerosol spray of the invention comprises: polar solvent 5-50%, active compound 1-40%, flavoring agent 0.05-5%. The soft bite gelatin capsule of the invention comprises as comprising as fill composition: polar solvent 75-99%, emulsifier 0-20%, active compound 0.03-35%, and flavoring agent 0.05-60%.Type: GrantFiled: November 25, 1998Date of Patent: August 29, 2000Assignee: Flemington Pharmaceuticals Co.Inventor: Harry A. Dugger, III
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Patent number: 6093823Abstract: The invention pertains to a process for the continuous production of basic cyclic optically active .alpha.-amino acids of general formula (I) by continuous racemate splitting via diastereomeric salt pairs with re-racemisation of the residual amino acid or amino acid derivative in the mother liquid with the aid of an optically active acid.Type: GrantFiled: March 24, 1998Date of Patent: July 25, 2000Assignee: Degussa AktiengesellschaftInventors: Matthias Kottenhahn, Klaus Stingl, Karlheinz Drauz
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Patent number: 6090049Abstract: Disclosed is a screen-type spirometer having an improved pneumotachometer, which has a simple structure and a low manufacturing cost and is convenient to use. According to the present invention, the pneumotachometer includes a hollow housing having an annularly shaped ring and a first respiratory tube integrally formed with the annularly shaped ring. The first respiratory tube can be inserted into a mouth of a person to be examined. The pneumotachometer also includes a second respiratory tube which can be engaged with the housing and be inserted into the mouth of the person. The first and the second respiratory tubes have a tapered portion, which is inclined at 10 degrees, respectively in order to stabilize a fluid flow of respiratory gases passing therethrough. O-shaped first and second sensing units for sensing a differential pressure of the respiratory gases passing through the pneumotachometer are disposed within the housing.Type: GrantFiled: July 24, 1998Date of Patent: July 18, 2000Inventor: Eun Jong Cha
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Patent number: 6080887Abstract: With known methods of racemizing N-acetyl-D(L)-.alpha.-amino carboxylic acids in the non-aqueous state by heating them to temperatures above room temperatures, significant quantities of by-products are formed, especially acetyl dipeptides. By converting at least a proportion of the N-acetyl-D(L)-.alpha.-amino carboxylic acids to corresponding N-acetyl-D(L)-.alpha.-amino carboxylic acid salts before or during the heating, it is possible to increase the sojourn time of the educt which is to be racemized at higher temperatures without any evident increase in the quantity of by-product formed (in particular acetylated dipeptides). Also disclosed is the production of optically active amino acids by enzymatic splitting of racemic compounds.Type: GrantFiled: June 10, 1998Date of Patent: June 27, 2000Assignee: Degussa AktiengesellschaftInventors: Karlheinz Drauz, Michael Karrenbauer, Andreas Bommarius, Gunter Knaup
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Patent number: 6068824Abstract: This invention discloses an adsorbent ideal or the removal of nitrogen oxides (NO.sub.x : nitrogen monoxide and nitrogen dioxide), particularly nitrogen dioxide, from an exhaust gas containing the nitrogen oxides at low concentrations and a method for efficient removal of nitrogen oxides, particularly nitrogen dioxide, from an exhaust gas containing the nitrogen oxides at low concentrations by the use of the adsorbent. The adsorbent either comprises at least one noble metal selected from the group consisting of Pt, Au, Ru, Rh, and Pd and/or a compound thereof supported on a carrier or comprises the noble metal component and an oxide of at least one heavy metal selected from the group consisting of Mn, Fe, Co, Ni, Cu, Zn and Pb, which may be supported on the carrier, if necessary.Type: GrantFiled: October 25, 1996Date of Patent: May 30, 2000Assignee: Nippon Shokubai Co., Ltd.Inventors: Futoru Kinoshita, Shinyuki Masaki, Hisao Kondo, Motonobu Kobayashi
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Patent number: 6063302Abstract: An aqueous iminocarboxylic acid salt solution composition the iminocarboxylic acid salt of which has a structure of the formula (II): ##STR1## wherein R is a hydrogen atom or a hydroxyl group and Y is a sodium atom, a potassium atom, or an ammonium group, contains an aspartic acid backbone moiety whose molar ratio of the isomers, i.e. D form/L form, is in the range of 1/0 to 0.7/0.3 or D form/L form, in the range of 0/1 to 0.3/0.7, and accounts for a concentration in the range of 40 to 70% by weight and a method for handling the composition while keeping the pH value thereof kept in the range of 7 to 12.Type: GrantFiled: October 18, 1995Date of Patent: May 16, 2000Assignee: Nippon Shokubai Co., Ltd.Inventors: Miaki Asakawa, Yasutaka Sumida, Yuichi Kita
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Patent number: 6061871Abstract: A handle release assembly includes a supporting bracket having two end portions each formed with a leg containing a first passage, a cover fixedly mounted on the supporting bracket and having two end portions and a mediate portion containing a second passage, two drawing bars each having one end portion extending through the first passage of the supporting bracket to be fixedly attached to the respective end portion of the cover and containing an elongate guiding slot, a pressing block slidably mounted in the second passage and having two end portions, and two pivot blocks each pivotally mounted in the cover and each having a first end portion formed with an ear pivotally connected with the respective end portion of the pressing block and a second end portion formed with a rod received in the guiding slot of the first end portion of the respective drawing bar.Type: GrantFiled: June 2, 1998Date of Patent: May 16, 2000Inventor: King-Sheng Wang
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Patent number: 6062036Abstract: The invention relates to a device for producing ice cubes. It has a freezer unit (6) with a plurality of freezing regions (7) accessible from the outside of said unit (6) for one ice cube (1) each, a device (9) for supplying the freezing regions (7) with an excess of water to produce clear ice and a dispensing region (1)) for ice cubes (1) released from the freezer unit (6). Between the freezer unit (6) and the dispensing region (19) there is a device (18) for putting two ice cubes (1) together to form a composite cube (1(A+B)). Said device (18) has adjacent storage devices for the ice cubes (1) to be put together which can be moved together in order to place the ice cubes (1) with plane damp surfaces together, where the path between the combining device (18) and the dispensing region (19), and the dispensing region (19) itself, are cooled to a temperature below 0.degree. C.Type: GrantFiled: April 6, 1998Date of Patent: May 16, 2000Inventor: Josef Hobelsberger
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Patent number: 6057422Abstract: There is provided a novel series of synthetic analogs of hGH-RH(1-29) NH.sub.2. These analogs inhibit the activity of endogenous hGH-RH, and therefore prevent the release of growth hormone. The stronger inhibitory potencies of the new analogs, as compared to previously described ones, results from replacement of various amino acids.Type: GrantFiled: November 25, 1998Date of Patent: May 2, 2000Assignee: The Administrators of the Tulane Educational FundInventors: Andrew V. Schally, Jozsef Varga, Marta Zarandi
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Patent number: D428214Type: GrantFiled: August 11, 1999Date of Patent: July 11, 2000Assignee: Magla World-Wide, L. L. C.Inventor: Henry Mattesky
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Patent number: D435299Type: GrantFiled: February 18, 2000Date of Patent: December 19, 2000Inventor: Jen-Chung Chou