Patents Represented by Attorney Paul S. Sabatine
  • Patent number: 5268209
    Abstract: The invention herein pertains to methods and materials for producing a nicotine maintenance pouch. Laminates comprising a nicotine barrier layer and a nicotine degradation agent barrier layer are disclosed. In a preferred embodiment, the nicotine barrier layer comprises a nitrile rubber modified acrylonitrilemethyl acrylate copolymer. An especially preferred nicotine barrier material comprises, by weight percent, 75% acrylonitrile, and 25% methyl acrylate with 10% butadiene (AN-MA/B). The nicotine degradation agent barrier layer is preferably aluminum foil. In an especially preferred embodiment, the laminate comprises a layer of AN-MA/B adhered to a layer of aluminum foil, which in turn is adhered to a layer of paper stock.Pouches comprising a self-sealed nicotine barrier layer and a nicotine degradation agent barrier layer are disclosed. These pouches are preferably formed from the laminates above.
    Type: Grant
    Filed: October 21, 1991
    Date of Patent: December 7, 1993
    Assignee: Alza Corporation
    Inventors: James A. Hunt, James L. Osborne, John T. Dunn, Melinda K. Nelson, Nathan Roth
  • Patent number: 5242391
    Abstract: Erectile dysfunction, particularly impotence, priapism and Peyronie's disease is treated by the transurethral administration of a therapeutically effective agent. The agents are administered to the urethra by means of a penile insert (1) having a rapidly releasing coating (4) containing the agent on its exterior surface or by means of an inserter (27) carrying an agent containing dose of agent (31) which can be displaced into the urethra.
    Type: Grant
    Filed: October 30, 1991
    Date of Patent: September 7, 1993
    Assignee: ALZA Corporation
    Inventors: Virgil A. Place, Robert M. Gale, Randall G. Berggren