Abstract: The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of catechins and vanilloids. Compositions of catechins include but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC). In a preferred embodiment the catechins have been treated with tannase. Compositions of vanilloids include, but are not limited to vanillylamine, the head group of capsaicin. The unique compositions of the invention contain various combinations of the catechins and vanilloids, in combination with each other or other therapeutic agents and are used to treat primary and metastatic cancers in humans. The invention also encompasses various modes of administration of the therapeutic compounds, including formulations which may be used as a dietary or nutritional supplement or as a therapeutic compound.

Abstract: The present invention relates to polyester resin for toner used for developing an electrostatic latent image such as a statically charged image in the electrostatic printing process and discloses polyester resin for toner comprising aromatic dicarboxylic acid, trivalent or higher carboxylic acid, aliphatic diol, bisphenol A derivative aromatic diol, and trihydric or higher alcohol, characterized in that the amount of the aromatic diol of bisphenol A derivative having the mole number of ethylene oxide and/or propylene oxide of 2mole is equal to or more than 85weight % in the entire aromatic diol of bisphenol A derivative, and the amount of the aromatic diol of bisphenol A derivative having the mole number of ethylene oxide or propylene oxide of 1mole is less than 0.2weight % in the entire aromatic diol of bisphenol A derivative.

Abstract: There is disclosed a bias circuit exhibiting good stability over variations in temperature and power supply voltage and capable of generating a plurality of discrete levels of output current for biasing RF power amplifier. In accordance with the invention, the bias circuit includes (1) a master transistor connected to the slave transistor in a current-mirror configuration and having two parallel-connected transistor elements, (2) a switch connected to at least one transistor element to control its operation, and (3) a feedback circuit by which the voltage at the collector of the master transistor may be fed back to control the voltages at the bases of the master transistor and the slave transistor. Moreover, the bias circuit can be operated from a power supply voltage that is just above twice the value of the base-emitter voltage of the transistor in the circuit.

Abstract: The present invention is directed to methods of treating or protecting mucosal tissue from damage associated with radiation and/or chemotherapeutic treatment of cancers, by the topical application of amifostine and related compounds. These methods avoid the side effects of systemically applied radio/chemo protectants. The invention is also directed to treatment and prevention of infections associated with mucositis by topical application of amifostine and related compounds.

Abstract: An implantable stent prosthesis comprises a sidewall and at least one channel for containing a biologically active material. A method for making such stent prosthesis is also disclosed. In the method, at least one tube or mandrel is placed in contact with a covering material on a stent and surrounded by the covering material to form a channel. Alternatively, a channel can be formed by covering tube or mandrel with a channel material and exposing the covered tube or mandrel to an appropriate treatment. The channel can be attached to a sidewall of a stent or attached to a strut material to form a stent wire. A method of treating an afflicted area of a body lumen by implanting the stent prosthesis is also disclosed.

Abstract: The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.

Abstract: The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells.

Abstract: The present invention provides a generally planar closed envelope device formed from material having vapor barrier properties, which envelope comprises a base layer (1) and a cover layer (4) applied to the base layer (1) and a continuous or discontinuous seal (4) therebetween, characterized in that: a) each of the base (1) and cover (3) layers carries a fluid composition (2) containing a liquid volatile material upon a selected area of the opposed faces thereof; f) the base (1) and cover (3) layers are formed by folding over a single piece of sheet material so as to bring the selected areas of the base (1) and cover (3) layers into opposing register with one another; and g) there is separable and reformable seal (4) between the base (1) and cover (3) layers to retain them in the folded configuration. The invention also provides a method for making such a device.

Abstract: The present invention relates to a purified, easily produced poly-&bgr;-1→4-N-acetylglucosamine (p-GlcNAc) polysaccharide species. The p-GlcNAc of the invention is a polymer of high molecular weight whose constituent monosaccharide sugars are attached in a &bgr;-1→4 conformation, and which is free of proteins, and substantially free of single amino acids, and other organic and inorganic contaminants. In addition, derivatives and reformulations of p-GlcNAc are described. The present invention further relates to methods for the purification of the p-GlcNAc of the invention from microalgae, preferably diatom, starting sources. Still further, the invention relates to methods for the derivatization and reformulation of the p-GlcNAc. Additionally, the present invention relates to the uses of pure p-GlcNAc, its derivatives, and/or its reformulations.

Abstract: A multi-compartment syringe for storing two or more substances in separate compartments comprises a tubular body having an opening at each end and a plunger. The body has two or more compartments defined along its length, where each compartment has a successively larger diameter. The plunger has a plunger head at one end that partitions the first and second compartments and one or more bungs, slidable along the plunger's shaft, for partitioning each of the other compartments. The plunger head and the bungs can be unsealed to establish a flow communication between the compartments.

Abstract: Apparatus and method for providing in-situ data of formation fluids at true reservoir conditions. The apparatus has NMR chamber of the flow-through type, so it is no longer necessary to divert a sample for the basic NMR analysis or transfer it uphole for laboratory analysis. The apparatus is preferably modular and is compatible with wireline tools configurable for a variety of sampling, testing and monitoring purposes. Fluid properties such as viscosity can be derived from diffusivities and relaxation times, as measured by NMR. Additional accuracy is provided in the downhole sampling process, and in the interpretation of NMR logs in real time at true reservoir conditions.

Abstract: A method and system are disclosed for counting errors occurring within an optical compact disk system as data is read from an optically encoded compact disk. In a preferred embodiment error flag data are generated as errors occur within the optical compact disk system. From the error flag data, error flag bits corresponding to errors in reading information from an optically encoded disk are identified for further processing. Further processing includes, among other things, keeping a total count of errors, keeping a count of single occurring errors, keeping a count of multiple occurring errors. Furthermore, by keeping error count information, the operation of the optical compact disk system may be interrupted upon the exceeding of a predetermined threshold. From the error count information the hardware, software and firmware within the optical compact disk system is optimized for increased performance.

Abstract: A hinge that has a first mounting base for attachment to a first hinged object. The hinge also has first and second hinge members pivotally connected together. The first hinge member and the first base are configured and dimensioned for cooperatively positioning and aligning the first hinge member in a plurality of mounted positions along the base length. At least one first locking member is associated with the first hinge member and the first base for locking the first hinge member to the first base in one of the mounted positions. The hinge may also be segmented. A positioning tool may be connected to at least the first base with an attachment portion and configured for positioning the first base and attachment portion on a first hinged object at a predetermined distance from the second hinge member.

Abstract: The present invention relates to a new and distinct cultivar of blackberry plant named Driscoll Cowles. The new cultivar is distinguished from other blackberry cultivars by its mid-late season crop, large fruit size and thornless canes. Driscoll Cowles produces fruit with improved quality and shipping characteristics. The new cultivar is distinguished from its seed parent by having larger fruit; it is distinguished from its pollen parent by its larger, better flavored fruit.

Abstract: The present invention relates to a new and distinct cultivar of raspberry plant named Driscoll Madonna. The new cultivar is distinguished from other raspberry cultivars by its large fruit with excellent fruit firmness and structure. The new cultivar is distinguished from its seed parent by having better flavor. The new cultivar is distinguished from its pollen parent by producing larger, firmer fruit.

Abstract: The present invention relates to a new and distinct cultivar of raspberry plant named Driscoll Maravilla. The new cultivar is distinguished from other raspberry cultivars by its fruit firmness, large size, high yield, and long post-harvest life. The new cultivar is distinguished from its seed parent by having larger and firmer fruit. The new cultivar is distinguished from its pollen parent by producing a higher yield of fruit and having shinier, brighter fruit.

Abstract: The present invention relates to a new and distinct cultivar of raspberry plant named Driscoll Francesca. The new cultivar is distinguished from other raspberry cultivars by its fruit firmness, fruit structure, yield and flavor. The new cultivar is distinguished from its seed parent by having better flavor, it is distinguished from its pollen parent by producing fruit of consistent shape and good firmness.

Abstract: Carburization and metal-dusting while hydrodealkylating a hydrodealkylatable hydrocarbon are reduced even in the substantial absence of added sulfur.

Abstract: The present invention relates to a new and distinct cultivar of raspberry plant named Driscoll Cardinal. The new cultivar is distinguished from other raspberry cultivars by its firm and very consistent fruit with regard to its size and shape throughout its harvest period. The new cultivar is distinguished from its seed parent by having larger fruit and more vigorous canes; it is distinguished from its pollen parent by producing a higher yield of fruit and better flavored fruit.

Abstract: The present invention relates to a new and distinct cultivar of raspberry plant named Dulcita. The new cultivar is distinguished from other raspberry cultivars by its fruit firmness, fruit structure, good flavor and yield. The new cultivar is distinguished from its seed parent by having larger fruit with better flavor. The new cultivar is distinguished from its pollen parent by producing a higher yield of fruit.