Patents Represented by Attorney Peters Verny, LLP
  • Patent number: 8347370
    Abstract: Systems and methods for authenticating electronic transactions are provided. The authentication methods employ a combination of security features and communication channels. These security features can be based, for example, on unique knowledge of the person being authenticated, a unique thing that the person has, unique personal features and attributes of the person, the ability of the person to respond, and to do so in a fashion that a machine cannot, and so forth. Methods for enrolling the person prior to authentication are also provided, as well as systems for enrollment and authentication.
    Type: Grant
    Filed: August 18, 2011
    Date of Patent: January 1, 2013
    Assignee: Veritrix, Inc.
    Inventor: Paul Headley
  • Patent number: 8343458
    Abstract: Activity-based probes, which are specific for certain active cysteine proteases (caspase, cathepsin and legumain) and carry radioactive labels, are disclosed. The present probes comprise an acyloxymethyketone (AOMK) “warhead” that binds only to active enzyme. The probes further comprise peptide-like structure that targets the probe to a specific cysteine protease or protease family, and a radiolabel on the probe, which is bound to the targeted enzyme. It has been found that the present probes are stable in vivo and give specific target images distinguishable over background. The preferred probes are labeled with a positron-emitting agent such as 64Cu, 125I (SPECT) and 99mTc (PET). The probes show in vivo half-life and stability well suited for imaging.
    Type: Grant
    Filed: April 3, 2009
    Date of Patent: January 1, 2013
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Matthew S. Bogyo, Galia Blum, Alicia Berger, Zhen Cheng, Sanjiv S. Gambhir
  • Patent number: 8342393
    Abstract: Systems and methods allow units of produce to be traced back to the fields in which the produce was grown. In the field, a harvest form is completed with harvest information at the time of the harvest. In some instances, labels having unique codes are used to label the produce in the field, and two additional labels are placed on the harvest form to associate a range of unique codes with the harvest information on the form. The labels used to label the produce can also be marked with a lot code and date at the time of harvest. In other instances, empty packages arrive at the field already marked with a range of associated unique codes. In the field, harvest information is recorded and associated with the range of unique codes by scanning one or more of the packages.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: January 1, 2013
    Assignee: YottaMark, Inc.
    Inventors: Elliott Grant, Matthew Self
  • Patent number: 8337735
    Abstract: Solder mold plates and methods of manufacturing the solder mold plates are provided herein. The solder mold plates are used in controlled collapse chip connection processes. The solder mold plate includes a plurality of cavities. At least one cavity of the plurality of cavities has a different volume than another of the cavities in a particular chip set site. The method of manufacturing the solder mold plate includes determining susceptible white bump locations on a chip set. The method further includes forming lower volume cavities on the solder mold plate which coincide with the susceptible white bump locations, and forming higher volume cavities on the solder mold plate which coincide with less susceptible white bump locations.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: December 25, 2012
    Assignee: Ultratech, Inc.
    Inventor: Lewis S Goldmann
  • Patent number: 8338364
    Abstract: Disclosed are peptides which inhibit the enzymatic activity of tyrosinase as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. Methods of skin treatment are also provided, the methods further including use of a peptide characterized by the amino acid sequence SFLLRN (SEQ ID NO: 1).
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: December 25, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Basil M. Hantash
  • Patent number: 8338947
    Abstract: Structure and methods of making the structures. The structures include a structure, comprising: an organic dielectric passivation layer extending over a substrate; an electrically conductive current spreading pad on a top surface of the organic dielectric passivation layer; an electrically conductive solder bump pad comprising one or more layers on a top surface of the current spreading pad; and an electrically conductive solder bump containing tin, the solder bump on a top surface of the solder bump pad, the current spreading pad comprising one or more layers, at least one of the one or more layers consisting of a material that will not form an intermetallic with tin or at least one of the one or more layers is a material that is a diffusion barrier to tin and adjacent to the solder bump pad.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: December 25, 2012
    Assignee: Ultratech, Inc.
    Inventors: Timothy H. Daubenspeck, Timothy D. Sullivan
  • Patent number: 8338477
    Abstract: The present disclosure is directed to compositions and methods which utilize the tetracycline scaffold, preferably the scaffold of tetracycline or minocycline, and which significantly lack antibiotic activity. The compounds have neuroprotective attributes without interfering with the drugs capacity to pass through the blood brain barrier. These compounds have neuroprotective activity because of their inhibition of neuronal cell cycle progression. The compounds are characterized in part by a fifth ring joining positions 9 and 10.
    Type: Grant
    Filed: July 10, 2009
    Date of Patent: December 25, 2012
    Assignee: NeuMedics
    Inventors: Iain W. Duncan, Edward A. Kesicki, Carl G. Osborne, William D. Schwieterman, Irina Jacobson
  • Patent number: 8334178
    Abstract: A double-gate semiconductor device includes a MOS gate and a junction gate, in which the bias of the junction gate is a function of the gate voltage of the MOS gate. The breakdown voltage of the double-gate semiconductor device is the sum of the breakdown voltages of the MOS gate and the junction gate. The double-gate semiconductor device provides improved RF capability in addition to operability at higher power levels as compared to conventional transistor devices. The double-gate semiconductor device may also be fabricated in a higher spatial density configuration such that a common implantation between the MOS gate and the junction gate is eliminated.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: December 18, 2012
    Assignee: ACCO Semiconductor, Inc.
    Inventors: Denis A. Masliah, Alexandre G. Bracale, Francis C. Huin, Patrice J. Barroul
  • Patent number: 8314500
    Abstract: An interconnection structure suitable for flip-chip attachment of microelectronic device chips to packages, comprising a two, three or four layer ball-limiting metallurgy including an adhesion/reaction barrier layer, and having a solder wettable layer reactive with components of a tin-containing lead free solder, so that the solderable layer can be totally consumed during soldering, but a barrier layer remains after being placed in contact with the lead free solder during soldering. One or more lead-free solder balls is selectively situated on the solder wetting layer, the lead-free solder balls comprising tin as a predominant component and one or more alloying components.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: November 20, 2012
    Assignee: Ultratech, Inc.
    Inventors: Luc Belanger, Stephen L. Buchwalter, Leena Paivikki Buchwalter, Ajay P. Giri, Jonathan H. Griffith, Donald W. Henderson, Sung Kwon Kang, Eric H. Laine, Christian Lavoie, Paul A. Lauro, Valérie Anne Oberson, Da-Yuan Shih, Kamalesh K Srivastava, Michael J. Sullivan
  • Patent number: 8313907
    Abstract: Methods and apparatus for direct detection of chemical reactions are provided. In a preferred embodiment, electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The target molecule is preferably DNA. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: November 20, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Nader Pourmand, Miloslav Karhanek, Ronald W. Davis
  • Patent number: 8314360
    Abstract: Apparatuses and methods are provided for processing a substrate having an upper surface that includes a central region, a peripheral region, and an edge adjacent to the peripheral region. An image having an intensity sufficient to effect thermal processing of the substrate is scanned across the upper surface of the substrate. The image scanning geometry allows processing the central region of the substrate at a substantially uniform temperature without damaging the outer edge. In some instances, the image may be formed from a beam traveling over at least a portion of the central region so that no portion thereof directly illuminates any portion of the edge when the image is scanned across the periphery region. The substrate may be rotated 180° or the beam direction may be switched after part of the scanning operation has been completed.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: November 20, 2012
    Assignee: Ultratech, Inc.
    Inventors: Boris Grek, David A. Markle
  • Patent number: 8314215
    Abstract: A linker system is provided where a small molecule reactive group, e.g., an activity based probe which binds to certain enzymes at the active site, is linked through an aryl diazo linker to an affinity molecule such as biotin. The reactive group may comprise a number of functionalities known to react with a specific target to be studied. This enables the probe to be exposed to analytes, such as proteins and bind specifically to them to form a complex having an affinity molecule allowing immobilization of the bound analyte on an affinity column or other support, e.g. with streptavidin. Then, the linker is cleaved without causing removal of the affinity group or dissociation of the probe from the analyte. The linker is cleaved under mild reducing conditions, e.g., dithionite. The probe is synthesized along with the linker on a solid support.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: November 20, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Matthew S. Bogyo, Steven H. L. Verhelst, Marko Fonovic
  • Patent number: 8313751
    Abstract: The invention relates to the use preferably of at least one active ingredient for the prophylaxis or therapy of a viral disease, wherein this active ingredient inhibits at least one component of the cellular signal transduction pathway for the activation of the transcription factor NF-kB such that virus multiplication is inhibited. The present invention relates furthermore to the local, preferably aerogenic, administration of the active ingredient according to the invention for inhibiting virus multiplication. The active ingredient according to the invention may be combined with at least one further antivirally effective substance for the prophylaxis or therapy of a viral disease.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: November 20, 2012
    Assignee: Activaero GmbH
    Inventors: Oliver Planz, Stephan Pleschka, Hans-Harald Sedlacek, Stephan Ludwig
  • Patent number: 8302796
    Abstract: Anti-theft devices are provided for use with both new and previously installed utility boxes. The utility box includes a sidewall, typically set into the ground, and the anti-theft device includes a bracket that hooks beneath the sidewall. The bracket also includes a threaded bore disposed through a fastening piece. The utility box also includes a cover that seals a top opening of the sidewall. The cover includes a hole for receiving a bolt. The threaded bore aligns with the hole in the cover so a bolt can engage the threaded bore to secure the cover to the bracket.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: November 6, 2012
    Assignee: Loc-Ets, Inc.
    Inventor: Clarence Johnson
  • Patent number: 8306664
    Abstract: Mobile self-balancing robots for telepresence are provided. The robots comprise a base, a head, and a shaft therebetween. The shaft can be telescoping to allow the head to be extended above the base to about the height of a normal sized person, or can be retracted to make the robot more compact for easier storage and transportation. The head includes components for telepresence such as cameras, a speaker, a microphone, a laser pointer, and a display screen, as well as protection from impacts and falls. The base provides locomotion and balance, and a narrow shaft between the head and base minimizes the robot's weight and reduces the likelihood of collisions with protrusions like table edges.
    Type: Grant
    Filed: May 17, 2010
    Date of Patent: November 6, 2012
    Assignee: Anybots 2.0, Inc.
    Inventors: Scott Wiley, Trevor Blackwell, Daniel Casner, Benjamin Holson
  • Patent number: 8300806
    Abstract: Systems and methods are provided that employ two or more cryptographically linked codes. The codes, when encrypted, become cipher texts that appear unrelated. The codes described herein are characterized by a series of bits including one or more switch bits. The cipher text of a code having a switch bit in one state will appear to be unrelated to the cipher text of another code differing only in that the switch bit is in the opposite state. The cryptographically linked codes can be used in various combinations, such as on a product and its packaging, on a product and a component of the product, on a certificate packaged with the product and on the packaging, or on outer and inner packagings of the product.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: October 30, 2012
    Assignee: YottaMark, Inc.
    Inventor: Elliott Grant
  • Patent number: 8296076
    Abstract: Disclosed is a method to achieve digital quantification of DNA (i.e., counting differences between identical sequences) using direct shotgun sequencing followed by mapping to the chromosome of origin and enumeration of fragments per chromosome. The preferred method uses massively parallel sequencing, which can produce tens of millions of short sequence tags in a single run and enabling a sampling that can be statistically evaluated. By counting the number of sequence tags mapped to a predefined window in each chromosome, the over- or under-representation of any chromosome in maternal plasma DNA contributed by an aneuploid fetus can be detected. This method does not require the differentiation of fetal versus maternal DNA. The median count of autosomal values is used as a normalization constant to account for differences in total number of sequence tags is used for comparison between samples and between chromosomes.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: October 23, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Hei-Mun Christina Fan, Stephen R. Quake
  • Patent number: 8293470
    Abstract: The present methods are exemplified by a process in which maternal blood containing fetal DNA is diluted to a nominal value of approximately 0.5 genome equivalent of DNA per reaction sample. Digital PCR is then be used to detect aneuploidy, such as the trisomy that causes Down Syndrome. Since aneuploidies do not present a mutational change in sequence, and are merely a change in the number of chromosomes, it has not been possible to detect them in a fetus without resorting to invasive techniques such as amniocentesis or chorionic villi sampling. Digital amplification allows the detection of aneuploidy using massively parallel amplification and detection methods, examining, e.g., 10,000 genome equivalents.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: October 23, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Stephen Quake, Hei-Mun Christina Fan
  • Patent number: 8286869
    Abstract: Rolls of pre-printed case labels are distributed at a harvest for labeling cases of produce. The labels on each roll include sequential codes that each span a unique range. Part or all of each roll's range can be associated with harvest data, including picker and block identifications. The association can be made by placing a label from each roll on a harvest form bearing harvest data, or by entering harvest data into an electronic device and using the device to read a unique code from a label. Pickers then harvest produce, fill cases, and label the cases from their rolls. The association of ranges to pickers allows a subsequently read unique code from a filled case to be properly credited to the correct picker. The association of ranges to blocks allows subsequently obtained quality information to be correlated to specific blocks.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: October 16, 2012
    Assignee: YottaMark, Inc.
    Inventor: Elliott Grant
  • Patent number: 8283012
    Abstract: Embodiments of the invention provide a composite sheet for creating a customized design. The composite sheet includes a first fabric portion, a second fabric portion, and a membrane portion disposed between the first fabric portion and the second fabric portion, where the first fabric portion is sewn with stitching to the second fabric portion. One advantage of the composite sheet and related systems and methods is that users can create customized designs conveniently on their own home printer.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: October 9, 2012
    Assignee: Ideo LLC
    Inventors: Vlasta Anastasia Komorous-Towey, Brian Benjamin Witlin, Joseph Berteel Wilcox, Gina Lynn Romero, Brendan John Boyle, James Adam Skaates