Patents Represented by Attorney, Agent or Law Firm Pillsbury Madison & Sutro
  • Patent number: 6274704
    Abstract: The biologically active peptide of the invention has a number of amino acids of 30 or less, comprises an amino acid sequence described as SEQ ID NO:13 (Tyr Thr Ile Tyr Val Ile Ala Leu) in the sequence listing and has cell adhesion inhibition activity. The peptide of the invention has short length and, therefore, synthesis and handling of the peptide are easy.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: August 14, 2001
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Fumio Fukai, Takashi Katayama
  • Patent number: 6271254
    Abstract: Pharmaceutical compositions and processes for their preparation containing R-&agr;-lipoic acid or S-&agr;-lipoic acid or pharmaceutically acceptable salts thereof. The pharmaceutical compositions have a cytoprotective activity and are suitable for combatting pain and inflammation.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: August 7, 2001
    Assignee: ASTA Pharma Aktiengesellschaft
    Inventors: Heinz Ulrich, Carl-Heinrich Weischer, Jürgen Engel, Helmut Hettche
  • Patent number: 6271971
    Abstract: The invention provides an objective system for use on a single objective type binocular stereomicroscope which, albeit having a parfocal length thereof shorter than a focal length thereof, can reduce various aberrations as much as possible, and a single objective type binocular stereomicroscope system which can be well manipulated while the viewing position is invariable even when objective lenses are interchanged. The objective system for use on a single objective type binocular stereomicroscope comprises an objective lens for converting light from an object into an afocal light flux and two viewing optical units for receiving light emanating from the objective lens to form left and right images, which satisfies condition: 1.0<FL/L<1.6 where FL is a focal length of the objective system, and L is a distance from a first lens surface of the objective system on an image point side to a sample surface.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: August 7, 2001
    Assignee: Olympus Optical Co., Ltd.
    Inventors: Kiyonobu Kurata, Kazuhiko Osa
  • Patent number: 6269290
    Abstract: In an engine-motor hybrid vehicle, vehicle drive regions are divided into a plurality of groups specified by a plurality of operation state variables. A learning variable set for each drive region is updated according to an amount of a power state of an engine, when the vehicle is in a steady state running. The learning variable indicates a change in the power state amount with age. When an engine power demand value is determined, it is corrected by using the learning variable of a selected drive region to calculate a corrected engine power demand value compensating a change in the engine with age. In this manner, the engine power is controlled.
    Type: Grant
    Filed: June 30, 1999
    Date of Patent: July 31, 2001
    Assignee: Denso Corporation
    Inventors: Tsuneyuki Egami, Kazuyoshi Obayashi, Hiroya Tsuji, Yasumasa Kaji, Keiichiro Banzai, Takeshi Sawada
  • Patent number: 6268894
    Abstract: A liquid crystal display apparatus having a plurality of pixel cells is disclosed, each of which comprising a scanning line and a signal line disposed on an insulation substrate in such a manner that the scanning line intersects with the signal line, a switching device disposed at the intersection of the scanning line and the signal line, a display pixel electrode electrically connected to the switching device, an opposite electrode disposed opposite to the display pixel electrode through a liquid crystal layer, and an auxiliary capacitor line disposed in a space between two adjacent display pixel electrodes in parallel with the scanning line and capacitively coupled with the display pixel electrode so as to form an auxiliary capacitor, wherein the scanning line overlaps with the display pixel electrode.
    Type: Grant
    Filed: May 31, 1996
    Date of Patent: July 31, 2001
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Yoshiro Aoki, Hajime Sato
  • Patent number: 6268152
    Abstract: Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: July 31, 2001
    Assignee: Affymetrix, Inc.
    Inventors: Stephen P. A. Fodor, Robert J. Lipshutz, Xiaohua Huang
  • Patent number: 6268021
    Abstract: A binder vehicle composition which is suitable for coating media, containing: A) 20 to 77% by weight of one or more binder vehicles based on oligomeric or polymeric polyol compounds with a hydroxyl number of 80 to 300, an acid number of 0 to 30, a number average molecular weight (Mn) of 500 to 10,000, and a glass transition temperature of −20 to +70° C.; B) 77 to 20% by weight of crosslinking agents based on aliphatic and/or cycloaliphatic polyisocyanates; C) 3 to 20% by weight of oligo- or polyesters, which contain carboxyl groups, as catalyst resins, which have an acid number of 210 to 300 mg KOH/g and a number average molecular weight (Mn) of 420 to 3000; and one or more organic solvents and/or water.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: July 31, 2001
    Assignee: Herberts GmbH
    Inventors: Carmen Flosbach, Friedrich Herrmann, Walter Schubert, Dirk Schild
  • Patent number: 6264809
    Abstract: One electrode is provided in association with the object to be coated, the other electrode. A pre-stretched ion-exchange membrane in a thin tubular form is sandwiched inbetween two nonconductive water permeable screen tubular housings. The assembly contains a supply line that provides a water way for the electrolyte to flow from the top of the device into a lower cap, then to the lower cap reservoir that allows stabilization and disbursement of electrolyte through the rifled housing Inertia developed through this defined pattern creates a swirling action that scrubs the impurities away from the anode, and to the top of the device to be carried out top. The location of the supply line is just inside the inner screen inserted through both the upper housing and lower cap. The tubular electrode is provided to the inside of membrane housing completing the inner portion of the waterway return chamber.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: July 24, 2001
    Assignee: PTI Advanced Filtration, Inc.
    Inventor: Cheng H. Lee
  • Patent number: 6261480
    Abstract: The thermistor element of the present invention is composed of a mixed sintered body aM1M2O3.bY2O3 of a composition M1M2O3 (wherein M1 is Y, and M2 is at least one element selected from the elements such as Cr, Mn, Ti, etc.) as a perovskite compound and Y2O3, wherein molar fractions a and b satisfy the relations 0.05≦a<1.0, 0<b≦0.95 and a+b=1. Another wide-range type thermistor element of the present invention is composed of a perovskite compound M1(M2M3)O3, wherein M1 is at least one element selected from the elements of the groups II and IIIA excluding La in the Periodic Table, and each of M2 and M3 is at least one element selected from the elements of the groups IIB, IIIB, IVA, VA, VIA, VIIA and VIII. a and b satisfy the relations a+b=1 and 0<b<0.1, where a is a molar fraction of M2 and b is a molar fraction of M3 in M1(M2M3)O3.
    Type: Grant
    Filed: August 25, 1999
    Date of Patent: July 17, 2001
    Assignees: Denso Corporation, Nippon Soken, Inc.
    Inventors: Itsuhei Ogata, Takumi Kataoka, Eturo Yasuda, Kaoru Kuzuoka, Masanori Yamada
  • Patent number: 6259919
    Abstract: A method for identifying a fast speed mobile station (MS) in a radio system, said method comprising measuring the frequency error of radio signals received from a mobile station. In order for a fast speed mobile station to be more reliably identified than before, the method comprises calculating the change (df) in BSC the frequency error from a time interval (t) of predetermined length, and identifying the mobile station as a fast speed mobile station if the change (df) in the calculated frequency error exceeds a predetermined limit value.
    Type: Grant
    Filed: February 14, 1997
    Date of Patent: July 10, 2001
    Assignee: Nokia Telecommunications Oy
    Inventors: Jukka Suonvieri, Kullervo Inkinen
  • Patent number: 6258547
    Abstract: cDNAs encoding mammalian AMP protein kinases, corresponding polypeptides and recombinant proteins together with antibodies thereto. Their uses including the study of gene expression and the characteristics of other proteins.
    Type: Grant
    Filed: March 6, 1996
    Date of Patent: July 10, 2001
    Assignee: Zeneca Limited
    Inventors: Rajinder Kumar Beri, David Carling, Robert Anthony Forder
  • Patent number: 6258933
    Abstract: The present invention relates to a process for the one-stage resalting and purification of oligopeptides. Oligopeptides are often not formed directly as acetates when synthesised. Acetate salts of oligopeptides are however desirable as bulk-active material for medical and formulation reasons. Processes known from the prior art have hitherto involved two separate steps or pyridine-containing solvents. The resalting and purification can be combined in one step and the use of pyridine as solvent can be avoided, if the oligopeptide in the form of its chloride salt is purified with an acetate-containing solvent by liquid chromatography methods.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: July 10, 2001
    Assignee: Degussa-Huls Aktiengesellschaft
    Inventors: Kurt Günther, Franz-Rudolf Kunz, Karlheinz Drauz, Thomas Müller
  • Patent number: 6249440
    Abstract: The contact arrangement is a connector block for detachably fastening an electrical component, particularly an integrated circuit having a plurality of terminal contacts disposed in a ball grid array (BGA), in a column grid array (CGA), in a land grid array (LGA) or of the flip-chip type to a printed circuit board. In a support part, a number of contact pins are disposed in a grid in bores. The contact pins project from the bore on the side facing the printed circuit board and are surface-mounted together with contact areas of the printed circuit board. A free end region of each bore is intended for guiding the substantially dome-shaped terminal contacts. Between the end of a contact pin and a terminal contact there is a space bridged for establishing an electrical connection with a contact element, for example an axially compressible coil spring. By means of several holding-down elements disposed peripherally to the integrated circuit, the integrated circuit is pressed down upon the support part.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: June 19, 2001
    Assignee: E-TEC AG
    Inventor: Hugo Affolter
  • Patent number: 6245825
    Abstract: Process for preparing a flexible foam by reacting a polyisocyanate having a high 4,4′-MDI content and a polyol having a high EO content in the presence of a foaming agent.
    Type: Grant
    Filed: July 2, 1996
    Date of Patent: June 12, 2001
    Assignee: Imperial Chemical Industries PLC
    Inventor: Geert Bleys
  • Patent number: 6246949
    Abstract: The present invention aims to facilitate easy correction of the center axis of an obstacle detecting apparatus for a vehicle by calculating deflection of the center axis with respect to the vehicle. Each of most obstacles recognized as moving objects is a preceding vehicle 93, and when the subject vehicle 91 is moving straight, the preceding vehicle 93 is detected in a position straight ahead of the subject vehicle 91. If the optical axis 95 of the transmitting/receiving section 31 is oriented straight ahead of the subject vehicle 91, the preceding vehicle 93 will be detected on the optical axis 95. On the other hand, when the optical axis 95 deviates from the center axis of the vehicle, the preceding vehicle 93 is detected in a position deviated from the optical axis 95 by an angle &thgr; m. In this case, the value &thgr; of deflection of optical axis 95 is equal to −&thgr; m.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: June 12, 2001
    Assignee: Denso Corporation
    Inventors: Noriaki Shirai, Katsuhiko Hibino, Takao Nishimura
  • Patent number: 6242792
    Abstract: A laser trimming is favorably performed by a strengthened laser beam energy. A level difference portion having a taper portion that is oblique with respect to the thicknesswise direction of a semiconductor substrate is formed at a surface of a semiconductor substrate. An insulating film is formed thereon and has its surface made flat, and then the thin film element is formed thereon. Thereafter, laser trimming is performed with respect to the thin film resistor. As a result, a state of interference between incident laser beam and reflected laser beam reflected from the interface between the semiconductor substrate and the insulating film is varied to thereby enable the production of a zone where laser beam energy is strengthened and a zone where laser beam energy is weakened.
    Type: Grant
    Filed: May 20, 1999
    Date of Patent: June 5, 2001
    Assignee: Denso Corporation
    Inventors: Shoji Miura, Satoshi Shiraki, Tetsuaki Kamiya, Makio Iida
  • Patent number: 6241797
    Abstract: There is disclosed a process for reducing oxidic slags or combustion residues above a metal bath. The metal bath is formed of an iron alloy containing metals nobler than iron and whose redox potential is adjusted such FeO is reduced to Fe not at all or only partially.
    Type: Grant
    Filed: April 16, 1997
    Date of Patent: June 5, 2001
    Assignee: “Holderbank” Financiere Glarus AG
    Inventor: Alfred Edlinger
  • Patent number: RE37292
    Abstract: An image display apparatus which enables observation of a clear image at a wide field angle with substantially no reduction in the brightness of the observation image, and which is extremely small in size and light in weight. The image display apparatus has an image display device (7) and an ocular optical system (8) for projecting the image of the image display device (7) and leading the projected image to an observer's eyeball (1). The ocular optical system (8) has at least three optical surfaces, and a space formed by these surfaces is filled with a medium having a refractive index larger than 1. The three optical surfaces are defined as a first surface (3), a second surface (4), and a third surface (5), respectively, in the order in which light rays pass in backward ray tracing from the observer's eyeball (1) to the image display device (7).
    Type: Grant
    Filed: May 21, 1999
    Date of Patent: July 24, 2001
    Assignee: Olympus Optical Co., Ltd.
    Inventors: Takayoshi Togino, Koichi Takahashi
  • Patent number: RE37314
    Abstract: The compounds of the present invention inhibit the HMG-CoA reductase, and subsequently suppress the biosynthesis of cholesterol. And they are useful in the treatment of hypercholesterolemia, hyperlipoproteinemia, and atherosclerosis.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: August 7, 2001
    Assignee: Shionogi Seiyaku Kabushiki Kaisha
    Inventors: Kentaro Hirai, Teruyuki Ishiba, Haruo Koike, Masamichi Watanabe
  • Patent number: RE37345
    Abstract: A multi-purpose laminating and adhesive transfer apparatus having a frame supporting rotatably engaging nip rollers. The frame and has upper and lower feed rolls which may be a laminate, film or paper, or an adhesively coated film or a film having an affinity for adhesive. The upper and lower feed rolls containing the webs of laminating or adhesive transfer material have tensioning caps which can be adjusted to provide the proper tensioning to prevent the rollers from overrunning as they rotate. The tensioning caps are pre-set and provided to the user. A cutter blade is positioned at the discharge side of the nip rollers and may be actuated to sever the master at any desired location. The apparatus may be operated to apply lamination to either top or bottom surfaces of a substrate.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: September 4, 2001
    Assignee: Xyron, Inc.
    Inventors: Franklin C. Bradshaw, Thomas L. Soderman