Patents Represented by Attorney, Agent or Law Firm R. Scott Meece
  • Patent number: 6582754
    Abstract: The invention relates to a process for coating a material surface, comprising the steps of: (a) covalently binding a compound comprising an ethylenically unsaturated double bond to the material surface; (b) polymerizing a monomer comprising a reactive or crosslinkable group on the surface and thereby providing a primary polymer coating comprising reactive or crosslinkable groups, (c) in case of a monomer comprising a reactive group in step (b) reacting the reactive groups of the primary coating with a further compound comprising an ethylenically unsaturated double bond and graft-polymerizing a hydrophilic monomer and optionally a co-monomer having a crosslinkable group onto the primary coating obtained according to step (b) and (d) in case of crosslinkable groups being present in step (b) or (c) initiating crosslinking of said groups.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: June 24, 2003
    Assignee: Novartis AG
    Inventors: Paul Pasic, Hans Jörg Griesser, Peter Kambouris, Peter Chabrecek
  • Patent number: 6582631
    Abstract: An improved method of cast molding contact lenses, wherein a lens forming mixture is cured in the lens-shaped cavity formed between molding surfaces of a male and female mold sections, wherein the improvement comprises at least one of sections is injection molded from a metallocene-catalyzed thermoplastic polyolefin.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: June 24, 2003
    Assignee: Novartis AG
    Inventor: Thomas Shepard
  • Patent number: 6579918
    Abstract: The invention provides a molded ophthalmic lens having at least first and second optical components, wherein the first optical component is cast molded to encapsulate the second optical component such that the first optical component provides an optical function and the second optical component provides an additional optical function. The invention additionally provides a process for producing a molded composite ophthalmic lens.
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: June 17, 2003
    Assignee: Novartis AG
    Inventors: Richard Dale Auten, John Martin Lally, Xiaoxiao Zhang
  • Patent number: 6568807
    Abstract: A contact lens is provided that has visible inversion marks on the lens. The marks include a plurality of recessed spots having side walls, a substantially convex bottom surface, and a relatively shallow maximum depth of between about 7.5 microns and 12 microns. The recessed spots provide a highly visible marking indicia on a contact lens with maximum comfort to wear. A method is also provided to make the inversion marks. The method includes projecting one or more laser beam pulses through a laser beam mask to etch an array of recessed spots in a surface of a contact lens mold insert and then scanning the insert and mask synchronously with respect to the laser beam pulses thereby forming the inversion mark on the mold insert. The mold insert is used to make casting cups for cast-molding contact lenses, through which the inversion marks are reproduced on the contact lenses.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: May 27, 2003
    Assignee: Novartis AG
    Inventors: Richard C. Rogers, Robert A. Broad, Gordon F. Maccabee, Stephen Williams
  • Patent number: 6569824
    Abstract: A method and composition for disinfecting a contact lens is disclosed. The method includes treating a lens with an aqueous solution having reduced toxicity to the eye which contains an effective amount of a monoperphthalic acid compound in a concentration of less than about 0.5% by weight of the solution. The lens disinfecting solution is capable of disinfecting contact lenses without irritating the eye due to reduced toxicity of the composition.
    Type: Grant
    Filed: February 7, 2001
    Date of Patent: May 27, 2003
    Assignee: Novartis AG
    Inventor: Fu-Pao Tsao
  • Patent number: 6555103
    Abstract: The present invention is concerned with a biomedical molding comprising a non-biodegradable biocompatible organic polymer comprising attached to its surface radicals of formula wherein the variables are as defined in the claims. The biomedical moldings of the invention are radiation sensitive and may be used, for example, as intraocular lens in ophthalmic surgery.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: April 29, 2003
    Assignee: Novartis AG
    Inventors: Jörg Leukel, Peter Chabrecek, Dieter Lohmann
  • Patent number: 6521352
    Abstract: The invention relates to a process for coating a material surface, comprising the steps of: (a) providing a hydrophilic telomer of formula (oligomer)-T  (1), wherein the variables are as defined in the claims, and (b) covalently binding the hydrophilic telomer to the material surface. The coated articles that are obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: February 18, 2003
    Assignee: Novartis AG
    Inventors: Peter Chabrecek, Dieter Lohmann
  • Patent number: 6511311
    Abstract: The present invention describes a carrier set for carrying ophthalmic lens molds. The carrier set has a front curve carrier, a back curve carrier, at least one spring in the front curve carrier or the back curve carrier, at least one stabilizing hole formed in one of the front curve and back curve carriers, at least one elongated stabilizing member attached to the carrier that does not have the stabilizing hole, and at least one locking bar in the carrier that has the stabilizing hole.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: January 28, 2003
    Assignee: Novartis AG
    Inventor: John Robert Popps
  • Patent number: 6503958
    Abstract: The present invention relates to porous polymers incorporating dihydroperfluoroalkyl acrylates and methacrylates and the like and their production. The invention also relates to the use of polymers derived from dihydroperfluoroalkyl acrylates and methacrylates and like compounds, in both porous and non-porous forms, as substrates for the attachment and growth of mammalian cells and tissue. The invention also relates to the use of polymers derived from dihydroperfluoroalkyl acrylates and methacrylates as components of medical devices and prostheses, including implanted devices.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: January 7, 2003
    Assignee: Novartis AG
    Inventors: Timothy Charles Hughes, Gordon Francis Meijs, Hassan Chaouk, John Gerard Steele, Graham Johnson
  • Patent number: 6502876
    Abstract: The invention is based on the problem of increasing the distance between the gripper and the mould half whilst maintaining the gripping power, so as to avoid damage to the contact lenses and the mould half, and of enabling the gripper to be simply aligned in relation to the mould half. This is solved by the usage of a spacer which is placed between the mould half and-the gripper. The distance between the mould half and the gripper is thereby increased without reducing the gripping, strength. In this way, damage to the mould half or the contact lens is avoided, and alignment of the gripper to the mould half is simplified. Moreover, the invention enables flaws in the periphery of the contact lens to be noticed more easily, since owing to the greater flux acting on the contact lens, the latter undergoes greater expansion in the end region of the gripper, thereby enabling possible flaws to be discerned more easily.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: January 7, 2003
    Assignee: Novartis AG
    Inventors: Holger Stockhorst, Günter Lässig, Peter Hagmann
  • Patent number: 6497000
    Abstract: The present invention discloses an apparatus for cleaning ophthalmic devices. The apparatus has a conveying system for transporting lens mold carriers to a cleaning station. The cleaning station has at least one movable cleaning assembly which is situated above the lens mold carrier and has a recess. When the cleaning assembly is lowered to the lens mold carrier, a substantially enclosed or enclosed cavity containing the lens mold is created by the carrier and the recess of the cleaning assembly. Compressed gas is injected into the cavity to dislodge any debris that may be present on the lens molds, and a vacuum is employed to remove gas and debris from the cavity.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: December 24, 2002
    Assignee: Novartis AG
    Inventor: Todd Aldridge Russell
  • Patent number: 6492478
    Abstract: The invention relates to novel crosslinkable prepolymers comprising structural units of the formula wherein the variables are as defined in the claims, to crosslinked polymers, to either homo-polymers or copolymers prepared from those novel prepolymers, to mouldings produced from the said homo- or co-polymers, and especially to contact lenses produced from those homo- or co-polymers.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: December 10, 2002
    Assignee: Novartis AG
    Inventor: Bettina Steinmann
  • Patent number: 6479587
    Abstract: The invention relates to novel crosslinkable prepolymers of formula (1), wherein the variables have the meanings given in the claims, to homo- or co-polymers obtainable therefrom by crosslinking and to mouldings, such as, especially, contact lenses, made from those homo- or co-polymers.
    Type: Grant
    Filed: March 16, 2000
    Date of Patent: November 12, 2002
    Assignee: Novartis AG
    Inventors: Friedrich Stockinger, Andreas Ackermann
  • Patent number: 6474465
    Abstract: The invention relates to a blister package for an optical lens and is concerned with the problem of improving the blister package in such a way that the base parts can be stacked and the work involved in sorting can be substantially reduced. This is achieved by perfecting spacing elements and joining several base parts to one unit (FIG. 2).
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: November 5, 2002
    Assignee: Novartis AG
    Inventor: Egbert Jux
  • Patent number: 6472489
    Abstract: The invention relates to novel polyallyl amine polymers having a weight average molecular weight of at least 2000 that, based on the number of amino groups of the polyallyl amine, comprises from approximately 1 to 99% of units of formula wherein R is as defined in the claims. The novel polyallyl amine polymers are useful, for example, for the surface-modification of different substrates or may be used for the manufacture of biomedical mouldings.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: October 29, 2002
    Assignee: Novartis AG
    Inventor: Friedrich Stockinger
  • Patent number: 6471891
    Abstract: A method of automatic manufacture of an astigmatic contact lens having a toric portion and a ballast portion such that said ballast portion causes the toric portion of the contact lens to properly orient in the eye of the wearer. The toric lenses are manufactured by moving a pallet containing at least half of a casting cup assembly and an information tag under a filling assembly and filling half of a casting cup assembly with liquid monomer, then moving the pallet to a closing assembly and, based on information obtained from the information tag, rotating one or both halves of the casting cup assembly and closing the casting cup assembly. The liquid monomer is then cured thereby creating a toric contact lens.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: October 29, 2002
    Assignee: Novartis AG
    Inventor: Robert Cameron
  • Patent number: 6471396
    Abstract: The invention relates to a method and a device for registering the presence of an ophthalmic moulding consisting of a biocompatible polymeric material, especially an ophthalmic lens, particularly a contact lens, in a package. The invention solves the problem through the use of an IR camera. Packages containing a moulding, especially a contact lens, have a change in their temperature distribution compared with a package without a contact lens. By evaluating the temperature difference, it is possible to determine whether or not there is a contact lens in a package. In particular, by using the detecting method according to the invention, one can determine whether there is a contact lens in the package directly after the filling procedure.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: October 29, 2002
    Assignee: Novartis AG
    Inventor: Roger Biel
  • Patent number: 6468667
    Abstract: The invention relates to an ophthalmic molding such as a contact lens or any kind of ocular prostheses comprising an organic bulk material having covalently bonded to its surface an acceptor saccharide to which is enzymatically attached one or more further carbohydrates. The ophthalmic moldings of the invention have desirable characteristics regarding, for example, adherence to the substrate, durability, hydrophilicity, wettability or biocompatibility.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: October 22, 2002
    Assignee: Novartis AG
    Inventors: Peter Chabrecek, Dieter Lohmann, Markus Streiff
  • Patent number: 6465056
    Abstract: The invention relates to a process for coating a material surface, comprising the steps of: (a) providing the material surface with polymer brushes comprising polymerization initiator radicals; and (b) graft polymerizing one or more different ethylenically unsaturated hydrophilic monomers or macromonomers onto the polymerization initiator-modified polymer brushes. The coated articles that are obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: October 15, 2002
    Assignee: Novartis AG
    Inventors: Peter Chabrecek, Dieter Lohmann
  • Patent number: 6454800
    Abstract: A corneal onlay or corneal implant is disclosed which is to be placed within or onto the surface of the cornea, being a biocompatible, optically transparent, synthetic and biostable polymeric material, said material comprising a surface that supports the attachment and growth of tissue cells, and where the exterior surface of the implant onto which epithelial tissue is to be attracted and to become attached, or in the case of a corneal onlay the anterior surface of the onlay, has a topography comprising a plurality of surface indentations.
    Type: Grant
    Filed: February 12, 2001
    Date of Patent: September 24, 2002
    Assignee: Novartis AG
    Inventors: Beatrice Ann Dalton, John Gerard Steele, Margaret Diana Macrea Evans, Janet Helen Fitton, Graham Johnson, Ilene Kay Gipson