Patents Represented by Attorney Robert L. Stone
  • Patent number: 5840281
    Abstract: An antiplaque composition comprising a bacteriocin such as nisin and a polyphosphonate.
    Type: Grant
    Filed: August 11, 1994
    Date of Patent: November 24, 1998
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, John Afflitto, Malathy Subramanian
  • Patent number: 5830388
    Abstract: A coagulating and flocculating agent based on aluminum pentahydroxychloride for purifying and treating water and/or waste water and/or sludge and/or other contaminated liquids as well as to separate suspended and colloidal particles from liquids in industrial manufacturing processes has its activity enhanced with an inorganic or organic flocculation enhancing additive such as natural or synthetic zeolite and/or cationic, anionic and non-ionic powdered, emulsified or liquid polyacrylamide. Aluminum pentahydroxychloride is formed by treating a natural nepheline, aluminum powder, aluminum oxide or other aluminum providing material with hydrochloric acid after which it is mixed with the flocculation enhancing additive.
    Type: Grant
    Filed: October 29, 1996
    Date of Patent: November 3, 1998
    Assignee: American EnviroCare, Inc.
    Inventors: Mark Y. Kigel, Mikhail Kofman, Mikhail Faylond, Tamara V. Vyshkina
  • Patent number: 5744563
    Abstract: A flocculant copolymer of acrylamide and Mannich base of acrylamide is provided which purifies and treats water and/or waste water, and/or sludge, and/or other contaminated liquids resulting from municipal discharges and industrial process effluents, as well as separating suspended and colloidal particles from liquids in industrial manufacturing processes. The copolymer has the general formula: ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 alkyl groups, R.sub.2 and R.sub.3 are C.sub.1 to C.sub.8 alkyl groups and may be the same or different.It is prepared in two stage reaction. In the first stage Mannich base of acrylamide is produced by reacting acrylamide with formalin and dimethylamine or other secondary C.sub.1-8 -alkylamines: ##STR2## and in the second stage copolymer of acrylamide and Mannich base of acrylamide is produced by polymerizing in the presence of redox-initiator system. The mole ratio of acrylamide to Mannich base of acrylamide of 1:(0.05-0.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: April 28, 1998
    Inventor: Tamara V. Vyshkina
  • Patent number: 5686064
    Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: January 28, 1994
    Date of Patent: November 11, 1997
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5681548
    Abstract: Oral compositions comprising the combination of an effective surface tension reducing amount of an amphoteric surfactant and an effective antimicrobial amount of a blend of phenolic agents is disclosed. These compositions are indicated in the management or control of dental plaque.
    Type: Grant
    Filed: March 29, 1995
    Date of Patent: October 28, 1997
    Assignee: Colgate Palmolive Company
    Inventors: Anthony Esposito, Ernest Kelly, John Afflitto, Abdul Gaffar
  • Patent number: 5599526
    Abstract: A visually clear gel dentifrice comprising a polishing agent having a refractive index of about 1.41 to 1.47, a substantially water-insoluble noncationic antibacterial agent, an aqueous water-humectant liquid vehicle having a refractive index with about 0.02 refractive index units of the refractive index of the polishing agent and surfactant which is a sulfated polyoxyethylene alcohol sodium or potassium salt or a weight mixture of at least 3:1 to sodium or potassium lauryl sulfate with the sulfated polyoxyethylene alcohol or a weight mixture of about 1:3 to about 3:1 of sodium potassium lauryl sulfate with an N-acyl-N-alkyl taurate sodium or potassium salt. The visually clear systems have reduced formation of surfactant crystals when subject to cool temperature.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: February 4, 1997
    Inventors: David B. Viscio, Michael Collins, Benjamin Y. Mandanas
  • Patent number: 5582816
    Abstract: Preparation of a visually clear gel dentifrice comprising a precipitated silica polishing agent having a refractive index of about 1.44, a water-swellable synthetic anionic polycarboxylate polymer which is added in solid form and a liquid vehicle comprising water and sorbitol wherein(a) when the total water content is above 30% to about 33% by weight of said dentifrice, sorbitol on a neat basis is present in amount of above 30% to about 36% by weight of said dentifrice(b) when the total water content is about 27% up to below 30% by weight of said dentifrice, sorbitol on a neat basis is present in amount of about 20% up to below 30% by weight of said dentifrice andother humectant if present, is in neat amount of up to 15% by weight of said dentifrice and also adding to said liquid vehicle about 1-4% by weight of dentifrice of solid water-swellable synthetic anionic polycarboxylate polymer.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: December 10, 1996
    Assignee: Colgate Palmolive Company
    Inventors: Benjamin Y. Mandanas, Eric Baines, Prakasarao Mandadi
  • Patent number: 5575652
    Abstract: An oral gel composition suitable for application to teeth and gums, particularly of people having dental implants. The gel composition contains an aqueous orally acceptable gel vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxyl-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces. The gel composition is extruded from a syringe into contact with a dental implant area thereby causing the composition to be delivered to and retained on the dental implant area.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: November 19, 1996
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, Ralph P. Santarpia, III
  • Patent number: 5538715
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methy cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.
    Type: Grant
    Filed: December 3, 1993
    Date of Patent: July 23, 1996
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5531982
    Abstract: A oral composition which inhibits plaque formation and reduces gingivitis and caries comprising a substantially water insoluble noncationic antimicrobial agent, such as triclosan and an acid reducing agent, such as xylitol. The composition is a dentifrice containing a siliceous polishing agent.
    Type: Grant
    Filed: July 14, 1994
    Date of Patent: July 2, 1996
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto
  • Patent number: 5525330
    Abstract: Oral composition containing an effective amount of N-methylpyrrolidone alone or in combination with a noncationic antibacterial agent such as Triclosan for topical application for the prevention of plaque, gingivitis and/or caries.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: June 11, 1996
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, John J. Afflitto, Malcolm I. Williams
  • Patent number: 5505933
    Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: April 9, 1996
    Assignee: Colgate Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5503823
    Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.
    Type: Grant
    Filed: June 27, 1994
    Date of Patent: April 2, 1996
    Assignee: Colgate Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5496540
    Abstract: An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula.
    Type: Grant
    Filed: January 10, 1994
    Date of Patent: March 5, 1996
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, Richard S. Robinson, Jeffrey Miller, Chimpiramma Potini, Michael A. Collins, Theresa G. Shackil
  • Patent number: 5486350
    Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: January 23, 1996
    Assignee: Colgate Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5472685
    Abstract: An antiplaque oral composition, such as a toothpaste, gel dentifrice, tooth powder, mouthrinse or mouthwash, tooth hardener, anticalculus composition, gum or lozenge, comprises triclosan as an antiplaque component, the antiplaque action of which is unexpectedly and beneficially increased by the presence in the oral composition of a phenolic flavoring agent, such as eucalpytol, thymol, methyl salicylate, menthol, phenol, halogenated derivatives thereof, and mixtures thereof. Preferred such compositions are toothpastes, gel dentifrices and mouthrinses or mouthwashes. Also within the invention are processes of repeatedly applying such antiplaque oral compositions to the teeth to obtain the antiplaque benefits mentioned.
    Type: Grant
    Filed: June 27, 1994
    Date of Patent: December 5, 1995
    Assignee: Colgate Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 5472684
    Abstract: A composition comprising thymol and eugenol, and optionally a sesquiterpene alcohol, such as, farnesol or has been found to have plaque and gingivitis effect. Flavoring agents may be included to provide an organoleptically acceptable oral product. Australian Tea Tree oil, sage oil and eucalyptol were found to enhance the antiplaque and antigingivitis activity of mouthrinses formulated from these compositions.These compositions exhibit an antibacterial effect vs. A. viscosus of about 25 MIC or less.
    Type: Grant
    Filed: June 2, 1993
    Date of Patent: December 5, 1995
    Assignee: Colgate Palmolive Company
    Inventors: Nuran Nabi, Abdul Gaffar, Shirley Lucchesi, John J. Afflitto, Susan M. Herles
  • Patent number: 5466437
    Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: December 3, 1993
    Date of Patent: November 14, 1995
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5453265
    Abstract: An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.
    Type: Grant
    Filed: January 13, 1994
    Date of Patent: September 26, 1995
    Assignee: Colgate Palmolive Company
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Drum Stringer, Michael Prencipe
  • Patent number: 5424059
    Abstract: A dentifrice which inhibits plaque formation and reduces gingivitis and caries comprising water-insoluble alkaline earth metal polishing agent such as dicalcium or dimagnesium phosphate or pyrophosphate, xylitol and a substantially water insoluble noncationic antibacterial agent, such as triclosan.
    Type: Grant
    Filed: December 1, 1993
    Date of Patent: June 13, 1995
    Assignee: Colgate Palmolive Company
    Inventors: Michael Prencipe, Anthony R. Volpe, Kedar N. Rustogi, Vincent O. Drago, Abdul Gaffar