Patents Represented by Attorney Robert L. Stone
  • Patent number: 5401723
    Abstract: Enhancement of the method and oral compositions for inhibiting adherence of Streptococcus pyogenes to pharyngeal and oral mucosa cells by treating these areas with a glycoconjugate comprising an oligosaccharide linked to a carrier. The oligosaccharide should have at least one fucose moiety or a galatose moiety which is free of digalactose and N-acetylneuraminyl lactose. The carrier may include albumins, starch or synthetic polymers.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: March 28, 1995
    Assignees: Colgate-Palmolive Company, Forsyth Dental
    Inventors: Abdul Gaffar, Ronald Gibbons, Stanislawa Tylewska
  • Patent number: 5374417
    Abstract: A dentifrice for desensitizing sensitive teeth wherein a potassium salt of a synthetic anionic polymer is present to close off subsequent penetration of pain to dental pulp.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: December 20, 1994
    Assignee: Colgate Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5356615
    Abstract: An antiplaque oral composition, such as a toothpaste, gel dentifrice, tooth powder, mouthrinse or mouthwash, tooth hardener, anticalculus composition, gum or lozenge, comprises triclosan as an antiplaque component, the antiplaque action of which is unexpectedly and beneficially increased by the presence in the oral composition of a phenolic flavoring agent, such as eucalpytol, thymol, methyl salicylate, menthol, phenol, halogenated derivatives thereof, and mixtures thereof. Preferred such compositions are toothpastes, gel dentifrices and mouthrinses or mouthwashes. Also within the invention are processes of repeatedly applying such antiplaque oral compositions to the teeth to obtain the antiplaque benefits mentioned.
    Type: Grant
    Filed: January 30, 1991
    Date of Patent: October 18, 1994
    Assignee: Colgate Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 5354550
    Abstract: A visually clear gel dentifrice comprising a polishing agent having a refractive index of about 1.41 to 1.47, a water-swellable synthetic anionic polycarboxylate polymer and a liquid vehicle of about 25-30% by weight water and 30-45% by weight of neat humectant wherein at least about 30% by weight of said dentifrice is neat sorbitol.
    Type: Grant
    Filed: April 12, 1993
    Date of Patent: October 11, 1994
    Assignee: Colgate Palmolive Company
    Inventors: Michael A. Collins, Joan M. Duckenfield
  • Patent number: 5344641
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methyl cellosolve and ethyl cellosolve; a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: September 6, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5334375
    Abstract: An oral composition containing a substantially water insoluble noncationic antibacterial antiplaque agent such as triclosan and a synthetic cross-linked polymer such as cross-linked poly (methylvinyl ether/maleic acid or anhydride) as antibacterial-enhancing agent to enhance delivery of said antibacterial agent to, and the retention thereof on, oral surfaces, and a method of promoting oral hygiene therewith.
    Type: Grant
    Filed: July 16, 1992
    Date of Patent: August 2, 1994
    Assignee: Colgate Palmolive Company
    Inventors: Nuran Nabi, Michael Prencipe, Abdul Gaffar
  • Patent number: 5312618
    Abstract: An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.
    Type: Grant
    Filed: December 2, 1992
    Date of Patent: May 17, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer, Michael Prencipe
  • Patent number: 5300283
    Abstract: A toothpaste or dental gel composition containing an amount of a synthetic linearly viscoelastic cross-linked polymeric thickening agent, especially a cross-linked methyl vinyl ether/maleic anhydride copolymer, effective to render the composition linearly viscoelastic, and a method of promoting oral hygiene by applying an effective amount of the composition to dental surface.
    Type: Grant
    Filed: October 22, 1992
    Date of Patent: April 5, 1994
    Assignee: Colgate Palmolive Company
    Inventors: Michael Prencipe, Gary A. Durga
  • Patent number: 5296214
    Abstract: An oral composition such as a dentifrice or mouth-wash, comprises an effective antiplaque amount of a substantially water-insoluble noncationic antibacterial agents, such as 2,4,4-trichloro-2'-hydroxy-diphenyl ether (Triclosan) and polyvinyl phosphonate antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to oral surfaces.
    Type: Grant
    Filed: August 4, 1992
    Date of Patent: March 22, 1994
    Assignee: Colgate-Palmolive Co.
    Inventor: Abdul Gaffar
  • Patent number: 5294431
    Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: October 16, 1992
    Date of Patent: March 15, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5292526
    Abstract: An oral composition such as a dentifrice, mouthwash, lozenge or chewing gum containing a polyphosphate anticalculus agent, such as tetraalkali metal pyrophosphate and antibacterial antiplaque agent compatible therewith. The antiplaque agent is a substantially water-insoluble noncationic antibacterial agent such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Triclosan). Antiplaque effectiveness is optimized by the presence of an antibacterial-enhancing agent which enhances delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: October 23, 1992
    Date of Patent: March 8, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5288480
    Abstract: An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, about 0.25-0.35% by weight of a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan) and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces.
    Type: Grant
    Filed: October 21, 1992
    Date of Patent: February 22, 1994
    Assignee: Colgate-Palmolive Co.
    Inventors: Abdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer
  • Patent number: 5279813
    Abstract: An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula.
    Type: Grant
    Filed: August 18, 1992
    Date of Patent: January 18, 1994
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaffar, Richard S. Robinson, Jeffrey Miller, Chimpiramma Potini, Michael A. Collins, Theresa G. Shackil
  • Patent number: 5279073
    Abstract: A vine stake having a sharp point at its lower end for penetrating soil adjacent to a growing vine, a solid flat upper end and along the exterior of its body, a plurality of protruding nodules or ruffles upon which vine-tieing ropes or straps can be rested. Desirably the vine stake comprises a hollow core below a solid flat upper end and is adapted for sub-irrigating vine roots by containing an ingress hole on the exterior of its body through which water or fertilizer solution or suspension can be introduced and also a plurality of egress holes in the exterior of its lower portion through which the water or liquid fertilizer can exit below the soil.
    Type: Grant
    Filed: September 9, 1991
    Date of Patent: January 18, 1994
    Inventor: Adolph S. Czebieniak
  • Patent number: 5273741
    Abstract: An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.
    Type: Grant
    Filed: July 30, 1992
    Date of Patent: December 28, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Abdul Gaftar, Richard S. Robinson, Jeffrey Miller, Chimpiramma Potini, Michael A. Collins, Theresa G. Shackil
  • Patent number: 5260062
    Abstract: A dental composition, such as a paste or gel dentifrice containing triclosan, as an antibacterial agent which acts to decrease plaque on the teeth, and polyphosphate for anti-tartar actions, is packaged in a finger actuatable pump-type plastic dispensing container which is made of or includes a solid polymeric material, such as a polyfluoroethylene, which is compatible with triclosan, so that excessive loss of its anti-plaque activity on storage is avoided, which losses have been noted when various other plastics have been employed as dispensing container component materials. Alternatively, others of such plastic may be employed for dispensing container parts when a stabilizer, such as a terpene, e.g., limonene, is present in the dentifrice.
    Type: Grant
    Filed: July 2, 1990
    Date of Patent: November 9, 1993
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar
  • Patent number: 5256401
    Abstract: An oral composition mouthwash or liquid dentifrice containing an aqueous vehicle acceptable vehicle including an alcohol, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-21'-hydroxy-diphenyl ether (triclosan) wherein the antiplague agent is entirely dissolved in the solvent and the weight ratio of water to alcohol is in excess of about 10:1.
    Type: Grant
    Filed: June 16, 1992
    Date of Patent: October 26, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Joan Duckenfield, Lori VanMeter, Shannon Campbell, Nuran Nabi
  • Patent number: 5252313
    Abstract: A visually clear gel dentifrice comprising a polishing agent having a refractive index of about 1.41 to 1.47, a water-swellable synthetic anionic polycarboxylate polymer and a liquid vehicle of about 25-30% by weight water and 30-45% by weight of neat humectant wherein at least about 30% by weight of said dentifrice is neat sorbitol.
    Type: Grant
    Filed: December 20, 1991
    Date of Patent: October 12, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: Michael A. Collins, Joan M. Duckenfield
  • Patent number: 5240697
    Abstract: An oral composition, such as a toothpaste, includes an anti-tartar proportion of a polyphosphate anti-tartar agent (preferably with synthetic anionic polymeric polycarboxylate or equivalent, and fluoride) and a desensitizing proportion of a tooth pain inhibiting potassium salt which passes through exposed dentin tubules to tooth nerves or neurons, which salt can be potassium nitrate, potassium citrate or potassium oxalate, so that it helps to prevent tartar from forming on the teeth and also lessens any pain experienced by persons contacting their sensitive teeth with the oral composition. Preferably the oral composition is a desensitizing anti-tartar toothpaste or gel which, when the teeth are brushed with it, aids in removal of at least some tartar and prevents its reappearance, and at the same time diminishes any tooth pain that the brusher would otherwise experience due to such brushing.
    Type: Grant
    Filed: October 17, 1991
    Date of Patent: August 31, 1993
    Assignee: Colgate-Palmolive Company
    Inventors: James Norfleet, Willie J. Carter, Matthew J. Frankel, Abdul Gaffar
  • Patent number: 5234688
    Abstract: A dental composition, such as a paste or gel dentifrice containing triclosan, as an antibacterial agent which acts to decrease plaque on the teeth, is packaged in a hand holdable and squeezable dispensing container which is made of or includes a part or parts of a solid polymeric material, such as a polyfluoroethylene or polyvinyl chloride, which is compatible with triclosan, so that excessive loss of its anti-plaque activity on storage is avoided, which losses have been noted when various other plastics have been employed as dispensing container component materials. Alternatively, other more reactive plastics may be employed for such dispensing container parts when a stabilizer, such as terpene, e.g., limonene, is present in the dentifrice.
    Type: Grant
    Filed: July 2, 1990
    Date of Patent: August 10, 1993
    Assignee: Colgate-Palmolive Company
    Inventor: Abdul Gaffar