Patents Represented by Attorney, Agent or Law Firm Robert W. Stevenson

Substituted benzylidene indenyl formamides, acetamides and propionamides

Patent number: 6403831

Abstract: Substituted benzylidene indenyl formamides, acetamides and propionamides are useful in the treatment of precancerous lesions and neoplasms.

Type: Grant

Filed: February 25, 2000

Date of Patent: June 11, 2002

Assignee: Cell Pathways, Inc.

Inventors: Gerhard Sperl, Paul Gross, Klaus Brendel, Rifat Pamukcu, Gary A. Piazza
Method of treating a patient having precancerous lesions with phenyl cycloamino pyrimidinone derivatives

Patent number: 6391885

Abstract: Derivatives of Phenyl Cycloamino Pyrimidinone are useful for the treatment of patients having precancerous lesions. These compounds are also useful to inhibit growth of neoplastic cells.

Type: Grant

Filed: May 4, 2000

Date of Patent: May 21, 2002

Assignee: Cell Pathways, Inc.

Inventors: Gary A. Piazza, Rifat Pamukcu
Method of inhibiting neoplastic cells with 4,5-diaminopyrimidine derivatives

Patent number: 6380206

Abstract: A method for inhibiting neoplasia, particularly cancerous and precancerous lesions by exposing the affected cells to 4,5-diaminopyrimidine derivatives.

Type: Grant

Filed: May 7, 2001

Date of Patent: April 30, 2002

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary Piazza
Method for treating neoplasia by exposure to substituted benzimidazole derivatives

Patent number: 6369092

Abstract: A method for inhibiting neoplastic cells and related conditions by exposing them to substituted benzimidalole derivatives.

Type: Grant

Filed: April 30, 2001

Date of Patent: April 9, 2002

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary A. Piazza
Method for treating a patient with neoplasia by treatment with a paclitaxel derivative

Patent number: 6365627

Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with a paclitaxel derivative.

Type: Grant

Filed: February 6, 2001

Date of Patent: April 2, 2002

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Kerstin B. Menander
Method of inhibiting neoplastic cells with indole derivatives

Patent number: 6358992

Abstract: A method for inhibiting neoplasia, particularly cancerous and precancerous lesions, by exposing the affected cells to indole derivatives.

Type: Grant

Filed: November 19, 1999

Date of Patent: March 19, 2002

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary A. Piazza
Method for treating a patient with neoplasia by treatment with a platinum coordination complex

Patent number: 6359002

Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an antineoplastic platinum coordination complex.

Type: Grant

Filed: February 6, 2001

Date of Patent: March 19, 2002

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Kerstin B. Menander
Method of inhibiting neoplastic cells with benzimidazole derivatives

Patent number: 6348032

Abstract: A method for inhibiting neoplasia, particularly cancerous and precancerous lesions by exposing the affected cells to benzimidazole derivatives.

Type: Grant

Filed: November 23, 1998

Date of Patent: February 19, 2002

Assignee: Cell Pathways, Inc.

Inventors: Gerhard Sperl, Rifat Pamukcu, Ulrich Ixkes, Gary A. Piazza
Indenyl hydroxamic acids, (hydroxy) ureas and urethanes for treating patients with precancerous lesions

Patent number: 6300346

Abstract: Indenyl hydroxamic acids, (hydroxy) ureas and urethanes are useful in the treatment of precancerous lesions and neoplasms.

Type: Grant

Filed: March 7, 2000

Date of Patent: October 9, 2001

Assignee: Cell Pathways, Inc.

Inventors: Gerhard Sperl, Paul Gross, Klaus Brendel, Rifat Pamukcu, Gary A. Piazza
Method for inhibiting neoplastic cells and related conditions by exposure to 2,9-disubstituted purin-6-ones

Patent number: 6268372

Abstract: A method for inhibiting the growth of neoplastic cells by exposure to 2,9-disubstituted purin-6-ones.

Type: Grant

Filed: September 11, 1998

Date of Patent: July 31, 2001

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary A. Piazza
Method of treating a patient having precancerous lesions with quinazoline derivatives

Patent number: 6262059

Abstract: Derivatives of Quinazoline are useful for the treatment of patients having precancerous lesions. These compounds are also useful to inhibit growth of neoplastic cells.

Type: Grant

Filed: April 6, 1998

Date of Patent: July 17, 2001

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary Piazza
Method of treating a patient having precancerous lesions with phenyl pyrimidinone derivatives

Patent number: 6239136

Abstract: Derivatives of Phenyl Pyrimidinone are useful for the treatment of patients having precancerous lesions. These compounds are also useful to inhibit growth of neoplastic cells.

Type: Grant

Filed: October 20, 1998

Date of Patent: May 29, 2001

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary Piazza
Method for treating a patient with neoplasia by treatment with a paclitaxel derivative

Patent number: 6235776

Abstract: This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with a paclitaxel derivative.

Type: Grant

Filed: November 12, 1998

Date of Patent: May 22, 2001

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Kerstin B. Menander
Method for treating patient having precancerous lesions with a combination of pyrimidopyrimidine derivatives and esters and amides of substituted indenyl acetic acides

Patent number: 6232312

Abstract: Combinations of substituted indenyl acetic acids and pyrimido-pyrimidine derivatives are useful in the treatment of colonic polyps and inhibiting the growth of neoplastic cells.

Type: Grant

Filed: February 20, 1998

Date of Patent: May 15, 2001

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary A. Piazza
Method for treating neoplasia by exposure to substituted 2-aryl-benzimidazole derivatives

Patent number: 6211177

Abstract: A method for inhibiting neoplasia, particularly cancerous and precancerous lesions, by exposing the affected cells to substituted 2-aryl-benzimidazoles.

Type: Grant

Filed: November 24, 1998

Date of Patent: April 3, 2001

Assignee: Cell Pathways, Inc.

Inventors: Gerhard Sperl, Ulrich Ixkes, Rifat Pamukcu, Gary A. Piazza
Method for treating neoplasia with amino or pyridylamino cyclobutene derivatives

Patent number: 6211220

Abstract: A method for inhibiting neoplasia, particularly cancerous and precancerous lesions by exposing the affected cells to amino or pyridylamino cyclobutane derivatives.

Type: Grant

Filed: November 23, 1998

Date of Patent: April 3, 2001

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary A. Piazza
Method for treating a patient having precancerous lesion with 4-phenylphthalazine derivatives

Patent number: 6207666

Abstract: Derivatives of 4-phenylphthalazine are useful for the treatment of patients having precancerous lesions. These compounds are also useful to inhibit the growth of neoplastic cells.

Type: Grant

Filed: April 23, 1998

Date of Patent: March 27, 2001

Assignee: Cell Pathways, Inc.

Inventors: Gary Piazza, Rifat Pamukcu
Method of treating a patient having precancerous lesions with phenyl purinone derivatives

Patent number: 6200980

Abstract: Derivatives of Phenyl Purinone are useful for the treatment of patients having precancerous lesions. These compounds are also useful to inhibit growth of neoplastic cells.

Type: Grant

Filed: April 17, 1997

Date of Patent: March 13, 2001

Assignee: Cell Pathways, Inc.

Inventors: Gary A. Piazza, Rifat Pamukcu
Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia

Patent number: 6200771

Abstract: A method for identifying compounds useful for the treatment of neoplasia involves acertaining whether such compounds exhibit an ability to inhibit a PDE that is characterized by cGMP specificity, cooperative kinetic behavior and insensitivity to phosphorylation.

Type: Grant

Filed: October 15, 1998

Date of Patent: March 13, 2001

Assignee: Cell Pathways, Inc.

Inventors: Li Liu, Rifat Pamukcu, W. Joseph Thompson, Gary A. Piazza, Han Li, Bing Zhu
Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives

Patent number: 6187779

Abstract: A method for inhibiting neoplastic cells and related conditions by exposing them to 2,8 disubstituted quinazolinone compounds.

Type: Grant

Filed: November 20, 1998

Date of Patent: February 13, 2001

Assignee: Cell Pathways, Inc.

Inventors: Rifat Pamukcu, Gary A. Piazza

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