Patents Represented by Law Firm Saidman, Sterne, Kessler & Goldstein
  • Patent number: 5066787
    Abstract: This invention discloses proteins which inhibit the coagulation of the blood, processes for preparing these proteins, and the use thereof.
    Type: Grant
    Filed: November 23, 1987
    Date of Patent: November 19, 1991
    Assignee: Boehringer Ingelheim International GmbH
    Inventor: Christian P. M. Reutelingsperger
  • Patent number: 5041829
    Abstract: A method of interpolating between two signals comprising the conversion of each signal into digital form and use of the converted signals to address a memory device at each address of which is pre-stored the result of interpolation for a particular combination of values of the signals.One embodiment of the method resides in a shaft angle encoder having: sensor means regulated by an encoder disc to produce two analogue output signals, analogue to digital conversion means which convert the said analogue signals, a memory device in which the said results are pre-stored and memory addressing means which use the converted signals to cause corresponding pre-stored results to be output from the memory device.
    Type: Grant
    Filed: August 20, 1986
    Date of Patent: August 20, 1991
    Assignee: Muirhead Vactric Components, Ltd.
    Inventor: David A. Garrett
  • Patent number: 5019921
    Abstract: A pop noise removing circuit for a double deck cassette tape recorder, which can thoroughly remove the pop noise occurring during the actuation of two deck leaf switches to drive deck motors. The circuit comprises means detecting ON-OFF operation of the deck leaf switches and generating control signals in response to the ON-OFF operation of the deck leaf switches, and means for muting left and right channel output signals from a head switching integrated circuit in dependence upon the control signals generated by the detecting means.
    Type: Grant
    Filed: October 12, 1988
    Date of Patent: May 28, 1991
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Yang M. Kang
  • Patent number: 5015058
    Abstract: An asymmetric multi-mode fibre optic coupler is assembled from two or more multi-mode optical fibres of different core and cladding diameters but substantially equal cladding refractive indices. The fibres are selected so as to have substantially equal effective refractive indices for their respective highest-order cladding modes, at least in the fabricated coupler.
    Type: Grant
    Filed: February 2, 1989
    Date of Patent: May 14, 1991
    Assignee: The Commonwealth of Australia
    Inventors: David A. Thorncraft, Peter R. A. Lyons, Scott C. Rashleigh, Johnathan A. Maine, John D. Love
  • Patent number: 5013652
    Abstract: A DNA sequence comprising:(a) a hybrid first yeast promoter comprising the functional segment of the DNA sequence encoding the upstream activation site of a gene selected from the group consisting of GAL1, GAL7 and GAL10, operably linked to the functional segment of the transcription initiation site of MF-.alpha.-1;(b) the functional segment of a signal sequence substantially comprising preferred yeast codons;(c) the functional segment of the DNA sequence comprising a Saccharomyces GAPDH transcription terminator;(d) the functional segment of the Saccharomyces 2.mu. circle replication origin; and(e) the functional segment of the yeast LEU2-d selectable marker. The DNA sequence may further comprise, inserted in phase between the signal sequence and transcription terminator, the functional segment of a DNA sequence encoding a heterologous target peptide.
    Type: Grant
    Filed: October 14, 1986
    Date of Patent: May 7, 1991
    Assignee: Genex Corporation
    Inventors: Robert L. Strausberg, Susan L. Strausberg
  • Patent number: 5011687
    Abstract: Purified Mullerian inhibiting substance (MIS) is obtained from testicular tissue by extraction, density gradient sedimentation and chromatography. The purified MIS has selective activity for inhibiting the growth of human ovarian cancer cells.
    Type: Grant
    Filed: October 29, 1985
    Date of Patent: April 30, 1991
    Assignee: The General Hospital Corporation
    Inventors: Patricia K. Donahoe, David A. Swann
  • Patent number: 5006992
    Abstract: An integrated system for process control in which a process supervisor procedure (which is preferably the top-level procedure) is configured as a modular software structure, with modules which can be revised by a user at any time, without significantly interrupting the operation of the process supervisor. The modular software structure can define control parameters for many process control procedures, and can retrieve data from many sources (preferably including a historical database of process data, which can provide time-stamped data). The supervisor can also call on various expert subprocedures. Preferably the expert subprocedures can also be modified by an authorized user at any time, by calling up and editing a set of natural-language rule templates which correspond to the rules being executed by the expert subprocedure.
    Type: Grant
    Filed: September 30, 1987
    Date of Patent: April 9, 1991
    Assignee: Du Pont de Nemours and Company
    Inventor: Richard D. Skeirik
  • Patent number: 5001225
    Abstract: A continuous hybridoma cell line, designated 7H8, which secretes a monoclonal antibody (MAb 7H8) of the IgM class and which binds to a protein present in species of the genus Plasmodium. MAb 7H8 also recognizes an antigen (antigen Pf93) unique to P. falciparum. Methods of isolating the substantially pure antigen using the antibody of the present invention are disclosed. MAb 7H8 is well suited for use in immunometric assays. Preferred is a two-sited assay developed with MAb 7H8. Anti-idiotypic and anti anti-idiotypic antibodies to MAb 7H8 are disclosed. The antibodies and antigens of the present invention are useful for immunodiagnostic and immunotherapeutic treatment of malarial diseases of man and animals.
    Type: Grant
    Filed: December 8, 1986
    Date of Patent: March 19, 1991
    Assignee: Georgetown University
    Inventor: Diane W. Taylor
  • Patent number: 4997645
    Abstract: Disclosed is a method of treating tumors capable of being treated with interferon which is comprised of interferon and dipyridamole, or pharmaceutically acceptable salts thereof, in amounts sufficient to enhance the anti-tumor effect of interferon. Further disclosed is a pharmaceutical composition comprised of interferon and dipyridamole.
    Type: Grant
    Filed: June 16, 1988
    Date of Patent: March 5, 1991
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Nobuo Suzuki, Yoshiaki Takakubo
  • Patent number: 4990452
    Abstract: The invention relates to modified subtilisin enzymes which have increased thermal stability. The modified subtilisin enzymes have at least two or more amino acid mutations which confer increased thermal stability. It has been discovered that combining individual stabilizing mutations in subtilisin frequently results in an additive increase in thermal stability. In addition, the invention pertains to cloned mutant genes coding for a subtilisin material having at least two amino acid substitution which has increased thermal stability.
    Type: Grant
    Filed: April 12, 1988
    Date of Patent: February 5, 1991
    Assignee: Genex Corporation
    Inventors: Philip N. Bryan, Michael W. Pantoliano
  • Patent number: 4989932
    Abstract: The invention is a multiplexer which enables light to be sent to and received from samples for simultaneous analysis. A multiplexer is described which uses a transverse probe to reflect light at an angle into an optical rod. The transverse probe is selectively rotated to transmit light to a second optical rod. Various numbers of optical rods may be used in the linear mutliplexer. A multiplexer is also described in which a conjugate optical barrel is utilized to selectively reflect light to various probes.
    Type: Grant
    Filed: March 3, 1989
    Date of Patent: February 5, 1991
    Assignee: LT Industries
    Inventors: Isaac Landa, Michael M. Anthony, George E. Toth
  • Patent number: 4985359
    Abstract: Vectors useful in the construction of cDNA libraries and methods for constructing these vectors are disclosed. According to the invention, a vector includes a polylinker region which is cut to linearize the vector. Oligo(dC) tails having terminal dideoxynucleotides are added to the two 3' ends of the vector. One oligo(dC) tail is removed and replaced with oligo(dT) to which poly(A) mRNA is annealed. The first complementary DNA strand is synthesized and tailed with oligo(dG), which anneals with the remaining oligo(dC) tail, thus circularizing the vector. The mRNA is digested and the second cDNA strand synthesized. Alternatively, the second cDNA strand can be synthesized before circularizing the vector. The resulting vector is used to transform microorganisms to create a cDNA library. The cDNA can be recovered by cleaving the vector at sites within the polylinker sequence.
    Type: Grant
    Filed: July 23, 1987
    Date of Patent: January 15, 1991
    Assignee: Ilse Oberbaumer
    Inventor: Ilse Oberbaumer
  • Patent number: 4983903
    Abstract: An automatic battery exhanging system for use with automatic guided vehicles which is capable of taking out the battery which is discharged below a threshold voltage of usefulness, mounting the battery to a recharging station, and after charging it, taking it back to the automatic guided vehicle so that the automatic guided vehicle may return to normal operation. This is completed under the control of a control unit. The invention comprises a battery mounting and dismounting means, a lifting means, a horizontal conveying means, a charging means, a dropping means, and control unit which automatically executes all of these operations.
    Type: Grant
    Filed: July 13, 1989
    Date of Patent: January 8, 1991
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Kisun Bae, Yunghoon Joo
  • Patent number: 4983547
    Abstract: In a method of forming a metallic silicide film on a substrate, a metallic silicide film containing silicon at a concentration higher than stoichiometric, is deposited on a substrate. A film of aluminum or aluminum alloy is then deposited on the metallic silicide film. Subsequently, a heat treatment is conducted to cause precipitation of silicon from the metallic silicide film to the aluminum, thereby to lower the silicon concentration in the silicide film.
    Type: Grant
    Filed: October 20, 1988
    Date of Patent: January 8, 1991
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventors: Junichi Arima, Yoshihiro Hirata, Hiroshi Harada, Isao Furuta, Shigeru Harada, Reiji Tamaki
  • Patent number: 4984033
    Abstract: A thin film semiconductor device is formed by preparing a substrate, forming a pattern of metal thin film on the substrate, forming an insulating layer on the metal thin film, and forming a pattern of a semiconductor thin film active layer over the pattern of the metal thin film by laser CVD.
    Type: Grant
    Filed: December 21, 1988
    Date of Patent: January 8, 1991
    Assignee: Mitsubishi Denki Kabushiki Kaisha
    Inventors: Akira Ishizu, Tadashi Nishimura, Yasuo Inoue
  • Patent number: 4981823
    Abstract: A ceramic article made from a mixture comprising (on a dry weight basis) magnesium oxide (MgO) in an amount up to 2% by weight, a defined rare earth oxide in amount up to 10% by weight, balance beryllium oxide, and trace elements, the defined rare earth oxide being zirconium oxide (ZrO.sub.2), hafnium oxide (HfO.sub.2), cerium oxide (Ce.sub.2 O.sub.3), yttrium oxide (Y.sub.2 O.sub.3), ytterbium oxide (Yb.sub.2 O.sub.3) or thorium oxide (ThO.sub.2). Such ceramic articles have much improved properties in particular higher densities than attainable hitherto and better crossbreak strength and surface smoothness as fired. The ceramic compositions can also be admixed with supplementary ceramic materials such as silicon carbide to produce microwave absorbing materials.
    Type: Grant
    Filed: December 7, 1988
    Date of Patent: January 1, 1991
    Assignee: CBL Ceramics Limited
    Inventors: Michael Crutchley, Ronald Stevens
  • Patent number: D313885
    Type: Grant
    Filed: February 13, 1990
    Date of Patent: January 22, 1991
    Assignee: Avia Group International, Inc.
    Inventors: Daniel Richard, James K. Tong, Peter Backus
  • Patent number: D315951
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: April 2, 1991
    Assignee: Life Technologies, Inc.
    Inventors: Mark Berninger, Michael Schuette
  • Patent number: D315952
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: April 2, 1991
    Assignee: Life Technologies, Inc.
    Inventors: Mark Berninger, Michael Schuette
  • Patent number: D317822
    Type: Grant
    Filed: February 14, 1990
    Date of Patent: July 2, 1991
    Assignee: Avia Group International, Inc.
    Inventors: Janelle Dahlsten, Craig Feller