Patents Represented by Attorney, Agent or Law Firm Sandra M. Nolan
  • Patent number: 5202350
    Abstract: New compounds (3-alkyl-5-hydroxy-3,4-dihydrofuran-2-ones) of the following general structure: ##STR1## wherein R is an alkyl group or a phenylalkyl group with the alkyl moiety containing at least 6 carbon atoms, are disclosed as useful in inhibiting phospholipase A.sub.2.
    Type: Grant
    Filed: August 29, 1991
    Date of Patent: April 13, 1993
    Assignee: Bristol-Myers Squibb Co.
    Inventors: F. Christopher Zusi, Suresh Marathe, William Somerville, Kenneth M. Tramposch
  • Patent number: 5164406
    Abstract: The present invention provides for a composition containing a pharmacologically active agent and a selected imidazole or an imidazole derivative, such composition exhibiting enhanced penetration of the pharmacologically active agent component when a composition containing the aforementioned components is applied to skin.A method of enhancing dermal penetration of compositions containing a pharmacologically active agent is also provided.
    Type: Grant
    Filed: May 22, 1989
    Date of Patent: November 17, 1992
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Michael D. Helman, Alison B. Lukacsko, Thomas A. Re, F. Christopher Zusi
  • Patent number: 5164413
    Abstract: Acne can be treated by applying to the skin of a subject a composition containing one of a certain group of acids, acid halides or amides.
    Type: Grant
    Filed: May 22, 1991
    Date of Patent: November 17, 1992
    Assignee: Bristol-Myers Squibb Company
    Inventor: Sandra L. Willis
  • Patent number: 5149752
    Abstract: Certain novel cationic polyelectrolytes are useful as components of formulations for treating keratinaceous and proteinaceous substrates.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: September 22, 1992
    Assignee: Clairol Incorporated
    Inventors: Janusz Jachowicz, Chittamuru Ramireddy
  • Patent number: 5116852
    Abstract: Certain antidepressants have been found to alleviate sleeping disorders associated with less than normal REM sleep.
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: May 26, 1992
    Assignee: Bristol-Myers Squibb Co.
    Inventor: Richard Gammans
  • Patent number: 5110809
    Abstract: Stable anhydrous gel formulations for topical antifungal use contain an imidazole, a steroid, a co-solvent system comprising monohydric and dihydric alcohols, and a hydroxyalkylcellulose gellant.
    Type: Grant
    Filed: October 23, 1990
    Date of Patent: May 5, 1992
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jonas Wang, Bhiku Patel, Stacley Au, Hemanshu Shah
  • Patent number: 5087620
    Abstract: Topical compositions are described which contain a vehicle which is free of lower alkanols, a pharmacologically active agent whose dermal penetration can be enhanced and a unique penetration control system. The control system contains an imidazole penetration enhancer and either propylene glycol alone or propylene glycol with an isopropyl ester of a fatty acid.
    Type: Grant
    Filed: May 17, 1990
    Date of Patent: February 11, 1992
    Assignee: Bristol-Myers Squibb Co.
    Inventor: Prakash Parab
  • Patent number: 5034420
    Abstract: This invention relates to an anthralin composition having improved stability. The invention further relates to a method for increasing the stability of anthralin in dermatological compositions by incorporating therein a stability enhancing amount of an acid stable anionic surfactant and a water soluble antioxidant.
    Type: Grant
    Filed: May 17, 1989
    Date of Patent: July 23, 1991
    Assignee: Bristol-Myers Squibb Co.
    Inventor: Jonas C. T. Wang
  • Patent number: 5034397
    Abstract: This invention relates to novel compositions of the antitumor agent [4'-9-(acridinylamino) methanesulfon-m-anisidide], (m-AMSA). Acid salts of m-AMSA are dissolved in 1-methyl-2-pyrrolidinone to provide highly stable solutions. The solutions may be diluted with Sterile Water for Injection, U.S.P. to provide stable, non-precipitating solutions for intravenous use.
    Type: Grant
    Filed: December 12, 1985
    Date of Patent: July 23, 1991
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Murray A. Kaplan, Robert A. Lipper
  • Patent number: 5015263
    Abstract: A composition for coloring skin comprising a carrier containing an alcohol component consisting of an aromatic alcohol, an aliphatic alcohol or mixtures thereof and certain certified acid dyes, said composition having an acid pH equal to or less than 4.
    Type: Grant
    Filed: August 12, 1988
    Date of Patent: May 14, 1991
    Assignee: Clairol Incorporated
    Inventors: Linda Albrecht, Leszek J. Wolfram
  • Patent number: 5002938
    Abstract: An antifungal gel composition, effective at 0.2-2.0% by weight of an imidazole antifungal agent and 0.01-2.5% by weight of a 17-ester corticosteroid antiinflammatory agent, is provided for topical administration. This composition is highly effective in treating fungal infections and is capable of being stored without refrigeration for long periods of time without losing therapeutic effectiveness and while maintaining the uniformity and stability of the gel.
    Type: Grant
    Filed: March 15, 1989
    Date of Patent: March 26, 1991
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jonas Wang, Bhiku Patel, Stacley Au, Hemanshu Shah
  • Patent number: 4983578
    Abstract: A novel air freshener composition and a combination product which uses same in an a device which has an emanator are described. The composition employs a combination of reagents which inhibit its evaporation so that the useful life of the air freshener is significantly lengthened.
    Type: Grant
    Filed: April 18, 1989
    Date of Patent: January 8, 1991
    Assignee: The Drackett Company
    Inventors: Donald Cashman, John A. Ferguson, George B. Keyes
  • Patent number: 4968497
    Abstract: The present invention relates to a method of imparting a controlled tanning of skin by treating the skin with an aqueous medium containing melanin or a precursor of melanin.
    Type: Grant
    Filed: August 26, 1988
    Date of Patent: November 6, 1990
    Assignee: Clairol Incorporated
    Inventors: Leszek Wolfram, Alexander C. Chan, Thomas M. Schultz, Bryan P. Murphy
  • Patent number: 4963287
    Abstract: Aqueous cleaner compositions containing an alkali metal halogenite, for example, sodium chlorite; a perfume normally chemically incompatible with the halogenite in aqueous media, and a stabilizing amount of an anionic surfactant, the inclusion of which enhances the stability of the perfume-containing aqueous halogenite compositions.
    Type: Grant
    Filed: November 1, 1988
    Date of Patent: October 16, 1990
    Assignee: The Drackett Company
    Inventors: Richard S. Hutchings, Saundra L. Nolte, Jeffrey S. Weaver
  • Patent number: 4916161
    Abstract: The unpleasant taste of ibuprofen or other bad-tasting pharmaceuticals can be mediated via wet granulation using certain taste masking agents.
    Type: Grant
    Filed: October 25, 1988
    Date of Patent: April 10, 1990
    Assignee: Bristol-Myers Squibb
    Inventor: Mahesh K. Patell
  • Patent number: 4915935
    Abstract: A composition of matter for depositing reflective particles on hair, said composition comprising solid reflective particles dispersed in a moderately fast-breaking foam, said foam being suitable for application to the hair.
    Type: Grant
    Filed: June 21, 1988
    Date of Patent: April 10, 1990
    Assignee: Clairol Incorporated
    Inventors: John F. Corbett, Girish V. Patel
  • Patent number: 4904274
    Abstract: A process for coloring hair in which a functional metal ion and aminoalkyl or aminohydroxyalkyl catechols are used in combination or applied sequentially to dye the hair rapidly.
    Type: Grant
    Filed: May 12, 1988
    Date of Patent: February 27, 1990
    Assignee: Clairol Incorporated
    Inventors: Thomas M. Schultz, Leszek J. Wolfram, Keith C. Brown, Giuseppe Prota
  • Patent number: 4902434
    Abstract: The neutralization of odors and removal of soil from fibrous surfaces, e.g., carpets, can be carried out using fabric treatment compositions containing certain combinations of metal salts and carriers.
    Type: Grant
    Filed: October 21, 1988
    Date of Patent: February 20, 1990
    Assignee: The Drackett Company
    Inventor: Lyndel D. Dickerson
  • Patent number: 4880556
    Abstract: Aqueous cleaner compositions containing an alkali metal halogenite, for example, NaClO.sub.2 ; a stabilizable colorant; and a stabilizing amount of a stabilizer compound selected from the group consisting of alkali metal carbonates, borates and mixtures thereof. The preferred embodiment further includes an anionic or anionic fluorocarbon surfactant.
    Type: Grant
    Filed: September 2, 1988
    Date of Patent: November 14, 1989
    Assignee: The Drackett Company
    Inventor: Richard S. Hutchings