Patents Represented by Attorney Sewall P. Bronstein
  • Patent number: 4358434
    Abstract: A method and kit for stabilizing solutions of radiolabelled compound by the use of insoluble quaternary ammonium containing compounds. Also described are novel insoluble compounds having quaternary ammonium and sulfide groups for use in the present invention.
    Type: Grant
    Filed: December 19, 1979
    Date of Patent: November 9, 1982
    Assignee: New England Nuclear Corporation
    Inventors: Nathan R. Tzodikov, Robert E. O'Brien
  • Patent number: 4358401
    Abstract: A liquid organic scintillation cocktail which is readily converted to a solid for disposal after use. Also disclosed are a method of disposal of radwaste employing the cocktail and a kit useful for practicing the method.
    Type: Grant
    Filed: March 31, 1980
    Date of Patent: November 9, 1982
    Assignee: New England Nuclear Corporation
    Inventors: Robert E. O'Brien, Jeanne K. Krieger
  • Patent number: 4354507
    Abstract: Improved disposable syringe for taking arterial blood samples for blood gas testing and for administerng epidural anaesthesia, wherein the syringe plunger has a compressible elastomeric tip member which has a peripheral annular wiper extending axially forwardly toward the syringe floor and radially outwardly at an acute angle to the longitudinal center line of the barrel and plunger to form an excellent seal with the inner surface of the syringe barrel while at the same time providing only a gentle pressure against such surface and hence an exceptionally low resistance to axial movement of the tip member and plunger.
    Type: Grant
    Filed: January 17, 1978
    Date of Patent: October 19, 1982
    Assignee: Concord Laboratories
    Inventor: Russell G. Raitto
  • Patent number: 4355236
    Abstract: An adjustable strength multipole permanent magnet is disclosed that comprises a plurality of axial layers of magnetic material wherein one layer can be angularly displaced with respect to an adjacent layer, each of said axial layers comprising a plurality of segments comprising an oriented, anisotropic,, permanent magnet material arranged in a ring, each segment having a predetermined easy axis orientation that is preferably determined by the formula:.alpha.=2.theta.where .theta. is the angle between the radial symmetry line of a segment and the X-axis and .alpha. is the angle between said radial line and the easy axis of the segment.
    Type: Grant
    Filed: April 24, 1980
    Date of Patent: October 19, 1982
    Assignee: New England Nuclear Corporation
    Inventor: Ronald F. Holsinger
  • Patent number: 4337240
    Abstract: Small sized material (less than 0.2 .mu.m, preferably less than 0.1 .mu.m) comprising a complex of (1) denatured albumin, particularly human serum albumin and (2) a metal reducing agent, particularly a stannous reducing agent, preferably formed in the presence of a stabilizing ligand, which complex, when labelled with technetium-99m provides an excellent agent for imaging or otherwise evaluating reticuloendothelial systems (RES) and/or components thereof, particularly the bone marrow, liver and/or lymphatic system; methods of making and using the same; a complex (physical or chemical) of technetium-99m with such materials and methods of using such latter complex.
    Type: Grant
    Filed: March 7, 1979
    Date of Patent: June 29, 1982
    Assignee: New England Nuclear Corporation
    Inventor: Eugene L. Saklad
  • Patent number: 4334008
    Abstract: Photosensitive compositions containing nitrate ester chain polymers, such as nitrocellulose, molecularly intimately admixed with at least one compound having a free basic amine group, preferably a primary amine group, directly attached to an aromatic ring carbon. On suitable exposure to ultraviolet light, such compositions will print out a useful image directly, or, should a much lesser light exposure be preferred, they can be developed and fixed to an image intensified to useful strength by either heat alone, for amines that are sufficiently volatile at ingredient reaction temperatures, or by solvent selective removal of ingredients from unexposed areas, and subsequently intensified either by heat or overall ultraviolet exposure. Exposed areas of such compositions are more resistant both to volatilization of the amines and to solvent removal than the non-exposed areas. High optical density is attainable using very thin coatings, permitting high resolution grainless images.
    Type: Grant
    Filed: May 29, 1980
    Date of Patent: June 8, 1982
    Assignee: Bard Laboratories, Inc.
    Inventors: John F. Rice, Albert P. Yundt, Kenneth J. Quast
  • Patent number: 4331948
    Abstract: The overload protection material of this invention comprises a plastic preferably an elastomer, e.g. silicone rubber, homogeneously and highly loaded with silicon carbide particles (powder) and a lesser amount of a Group IV B element-carbide particles (powder). The material is preferably form stable and is placed (across) a semiconductor junction or between electrodes of a device to be protected so that when high voltage surges appear across the junction or device to be protected the material breaks down (conducts) before the junction or device is destroyed. The material is bidirectionally conductive in its voltage threshold characteristic and repeatedly recovers unlike a fuse so that it provides continuous high voltage over-voltage (e.g. surge) protection.
    Type: Grant
    Filed: August 13, 1980
    Date of Patent: May 25, 1982
    Assignee: Chomerics, Inc.
    Inventors: Paul J. Malinaric, Vincent Squitieri
  • Patent number: 4330507
    Abstract: A method for generating Ga-68 from Ge-68 is provided that comprises contacting a substrate on which Ge-68 has been adsorbed with an alkaline solution having a pH of at least about 12 and thereby eluting Ga-68. Preferably the Ga-68 is eluted in the form of the gallate ion. A generator system comprises a generator column containing Ge-68 and Ga-68, a sealed eluant container having a predetermined quantity of eluant comprising an alkaline solution having a pH of at least about 12, and an evacuated eluate collection vial having a vacuum sufficient to draw the desired quantity of eluate into the eluate collection vial. The eluate collection vial can contain a neutralizing agent and also a diagnostically useful complexing agent.
    Type: Grant
    Filed: June 11, 1980
    Date of Patent: May 18, 1982
    Assignee: New England Nuclear Corporation
    Inventor: Robert E. Lewis
  • Patent number: 4315906
    Abstract: A highly purified, biologically active cold insoluble globulin (CIG) preparation is provided having specific opsonic activity of at least 1000 units per mg of CIG. Methods of purifying CIG using affinity antibody columns are described in which the biological activity of the purified CIG is greater than 95% of the activity of the starting material.The purified CIG can be radiolabelled and radiopharmaceutical preparations containing such CIG are useful as scanning agents for in vivo localizing of areas where CIG-binding determinants are expressed. Such areas include thrombi and damaged tissue such as burns, heart, liver, spleen, muscle, skin, kidney and the like. These areas of localized radiolabelled CIG can be visualized with a gamma camera.
    Type: Grant
    Filed: May 21, 1979
    Date of Patent: February 16, 1982
    Assignee: New England Nuclear Corporation
    Inventor: Frank B. Gelder
  • Patent number: 4312934
    Abstract: Photosensitive compositions containing nitrate ester chain polymers, such as nitrocellulose, molecularly intimately admixed with at least one compound having a free basic amine group, preferably a primary amine group, directly attached to an aromatic ring carbon. On suitable exposure to ultraviolet light, such compositions will print out a useful image directly, or, should a much lesser light exposure be preferred, they can be developed and fixed to an image intensified to useful strength by either heat alone, for amines that are sufficiently volatile at ingredient reaction temperatures, or by solvent selective removal of ingredients from unexposed areas, and subsequently intensified either by heat or overall ultraviolet exposure. Exposed areas of such compositions are more resistant both to volatilization of the amines and to solvent removal than the non-exposed areas. High optical density is attainable using very thin coatings, permitting high resolution grainless images.
    Type: Grant
    Filed: May 29, 1980
    Date of Patent: January 26, 1982
    Assignee: Bard Laboratories, Inc.
    Inventors: John F. Rice, Albert P. Yundt, Kenneth J. Quast
  • Patent number: 4297522
    Abstract: A flat cable shielding device comprises a metal foil sleeve formed of an upper and a lower length of conductive metal foil. To aid the insertion of flat cable into the shielding device, a low-friction inside surface is provided on the inside surface of the metal foil sleeve. The outside of metal foil sleeve is covered with an electrically insulating film, to provide wear and scuff protection. Both the low-friction inside surface and other outer coating are coupled to the metal foil sleeve preferably using adhesive. Good electrical connections can be made easily to the shielding device which can be used as a floating ground or can be grounded to a common system ground as desired.
    Type: Grant
    Filed: September 7, 1979
    Date of Patent: October 27, 1981
    Assignee: TME, Inc.
    Inventors: Harold W. Jesse, Peter M. Jones
  • Patent number: 4293436
    Abstract: An improved method of enhancing the effect of weak, e.g. beta, radioactive emitters, such as tritium and carbon-14, on film by contacting the medium used to contain the radioactive emitter with a fluor dissolved or dispersed in a carboxylic acid.A new composition of matter for performing such a method, comprising a fluor dissolved or dispersed in a carboxylic acid.An article of manufacture comprising an aqueous separation medium impregnated with a fluor and a solvent.
    Type: Grant
    Filed: March 30, 1979
    Date of Patent: October 6, 1981
    Assignee: New England Nuclear Corporation
    Inventor: Dennis L. Fost
  • Patent number: 4278653
    Abstract: Methods and kits for performing a double antibody immunoassay are described. The immunoassay comprises:reacting an antigen and a labelled version of said antigen with a first antibody against said antigen and said first antibody with a second antibody against said first antibody to precipitate a complex of said antigen, said first antibody and said second antibody, andprecipitating a colored protein to form a precipitate comprised of said complex and colored protein.In a preferred embodiment, the first and second antibodies can be prereacted to simplify the assay procedure.
    Type: Grant
    Filed: February 1, 1979
    Date of Patent: July 14, 1981
    Assignee: New England Nuclear Corporation
    Inventors: S. Richard Harris, Darlene K. Bonci
  • Patent number: 4277751
    Abstract: The drive signal applied to the drive winding of a magnetometer is provided by a voltage controlled oscillator. The average current flowing through the drive winding is monitored, and a signal representative of the average current is applied to the input of the voltage control oscillator. The sense windings of the magnetometer are connected to a servo-loop which causes a current to flow in the sense windings which produces a magnetic field cancelling the sensed components of the earth's magnetic field. The magnetometer uses a drive signal which saturates the core for only a short duration of time thereby reducing the power required by the magnetometer while ensuring complete saturation of the core.
    Type: Grant
    Filed: September 29, 1978
    Date of Patent: July 7, 1981
    Assignee: Neil Brown Instruments Systems, Inc.
    Inventors: Kenneth D. Lawson, Neil L. Brown
  • Patent number: 4272503
    Abstract: Reductant compositions for reducing technetium to produce technetium labelled ligands comprise a substrate having attached thereto a reducing complex having sufficient redox potential to reduce technetium from the +7 oxidation state. Preferably the reducing complex comprises a reducing agent for technetium and a chelating ligand therefor. Technetium labelled ligands are prepared by mixing such ligands with pertechnetate in the presence of the reductant of this invention and separating the reductant from the resulting labelled ligand. Technetium labelled ligands that are substantially free from reducing agent used in their preparation may be made in this manner.
    Type: Grant
    Filed: May 25, 1978
    Date of Patent: June 9, 1981
    Assignee: New England Nuclear Corporation
    Inventors: Leopoldo L. Camin, Maria P. Liteplo
  • Patent number: 4266936
    Abstract: A portable braille display unit which presents an entire page of braille characters in response to data stored on a storage medium, such as a tape cassette. The display unit is the size of a conventional braille page, and the display unit may be made portable and self-powered. Each braille character is displayed by a braille cell display module in which spring actuated pins are controlled by bimetallic latches. Each module includes six pins which comprise the six dots of each braille cell. To display braille characters, an electrical current is applied to resistively heat selected ones of the bimetallic latches. In response to this current the selected bimetallic latches bend and disengage from the pin, allowing a compressed spring to move the pin upward through the surface plate to display a braille dot. The spring maintains the pin in this position without requiring power from the power supply.
    Type: Grant
    Filed: November 6, 1978
    Date of Patent: May 12, 1981
    Assignees: Leonard Rose, Stanley Rose
    Inventors: Leonard Rose, Stanley E. Rose
  • Patent number: 4251734
    Abstract: A report cover with a display device comprising at least two sheets hingedly connected for folding as an inside cover and a third sheet hingedly connected to one of said aforementioned sheets and acting as the bottom cover, said first two mentioned sheets when folded having substantially coextensive confronting surfaces, printed circuits on the confronting surfaces embodying contact areas engageable by pressing the sheets together to complete a current path in the circuitry, cell means on the confronting face of the one sheet, terminal means on the confronting face of the other sheet, the poles of said cell means being engageable with said terminal means by pressing the sheets together to insert a source of current in the circuitry, a light emitting diode connected in the circuitry adapted to be energized by completion of a current path by pressing a pair of confronting contact areas together, means on the outer face of the one sheet indicative of the location poles and the contact areas at the inner side of
    Type: Grant
    Filed: May 4, 1979
    Date of Patent: February 17, 1981
    Assignee: Chomerics, Inc.
    Inventors: Carl P. Mayer, Robert A. Rothenberg
  • Patent number: 4245654
    Abstract: Improved disposable syringe for taking blood or other fluid samples, particularly arterial samples for blood gas testing or the like, which comprises a syringe body, a piston or plunger having a compressible end piece which forms a seal with the inner surface of the syringe body, the syringe body having a non-tapered section through which the end piece moves during withdrawal of the piston and preferably means for resisting further movement of the end piece when the desired sample size has been obtained. Also preferably the syringe has means which prevent contact between the compressible end piece and the end wall of the syringe.
    Type: Grant
    Filed: March 22, 1977
    Date of Patent: January 20, 1981
    Assignee: Concord Laboratories, Inc.
    Inventor: Russell G. Raitto
  • Patent number: 4246497
    Abstract: A circuit for measuring the relative phase of two periodic signals. Two analog waveforms are applied to limiting amplifiers which provide digital output signals. The output signals therefrom are applied to digital circuitry which provides an analog voltage representative of the phase difference between the two input signals over a 360 degree range. The digital circuitry compensates for any offset errors which may be introduced by the limiting amplifiers.
    Type: Grant
    Filed: September 29, 1978
    Date of Patent: January 20, 1981
    Assignee: Neil Brown Instruments Systems, Inc.
    Inventors: Kenneth D. Lawson, Neil L. Brown
  • Patent number: D258288
    Type: Grant
    Filed: August 4, 1978
    Date of Patent: February 17, 1981
    Assignee: Tamura Electric Works, Ltd.
    Inventors: Chuta Aikawa, Keizo Minemura