Patents Represented by Attorney Suet M. Nath & Associates Chong

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  • Phosphinic acid derivatives
    Patent number: 6121252
    Abstract: The present invention relate to phosphinic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase activity and to treat glutamate abnormalities and prostate diseases.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: September 19, 2000
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Paul F. Jackson, Takashi Tsukamoto, Yao-Sen Ko, Barbara S. Slusher
  • Phosphinic alkanoic acid derivatives
    Patent number: 6071965
    Abstract: The present invention relate to phosphinic alkanoic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase activity and to treat glutamate abnormalities and prostate diseases.
    Type: Grant
    Filed: December 31, 1997
    Date of Patent: June 6, 2000
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Paul F. Jackson, Weixing Li, Keith M. Maclin, Kevin L. Tays, Takashi Tsukamoto, Barbara S. Slusher
  • Phosphonic acid derivatives
    Patent number: 6054444
    Abstract: The present invention relates to phosphonic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising such derivatives, and methods of using such derivatives to inhibit NAALADase activity, to treat a glutamate abnormality and to treat a prostate disease in an animal.
    Type: Grant
    Filed: April 24, 1997
    Date of Patent: April 25, 2000
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Paul F. Jackson, Keith M. Maclin, Kevin L. Tays, Barbara S. Slusher
  • Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
    Patent number: 6017903
    Abstract: The present invention relates to a method of treating a glutamate abnormality and a method of effecting a neuronal activity in an animal using a NAALADase inhibitor, and a pharmaceutical composition comprising an effective amount of a NAALADase inhibitor for treating a glutamate abnormality and effecting a neuronal activity in an animal.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: January 25, 2000
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Barbara S. Slusher, Paul F. Jackson, Kevin L. Tays, Keith M. Maclin
  • Pharmaceutical compositions and methods of treating compulsive disorders using NAALADase inhibitors
    Patent number: 5977090
    Abstract: The present invention relates to a pharmaceutical composition and a method for treating a compulsive disorder using a NAALADase inhibitor.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: November 2, 1999
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Barbara S. Slusher, Paul F. Jackson, Kevin L. Tays, Keith M. Maclin
  • Pharmaceutical compositions and methods for treating compulsive disorders using pyrrolidine derivatives
    Patent number: 5925666
    Abstract: The present invention relates to pharmaceutical compositions and methods for treating compulsive disorders using pyrrolidine derivatives.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: July 20, 1999
    Assignee: Guilford Pharmaceuticals Inc.
    Inventors: Paul F. Jackson, Barbara S. Slusher
  • Suspension fertilizer suitable for irrigation fertilization, and a process for its preparation
    Patent number: 5851260
    Abstract: The invention relates to a stable aqueous fertilizer suspension suitable for drip irrigation, which suspension contains 5-55% by weight water and 45-95% by weight of one or several plant-nutrient containing substances, of which at least one contains water-insoluble solid particles, the particle size of the solid particles contained in the suspension being less than 50 .mu.m and the pH of the suspension being within the range 2-7. The invention also relates to a process for the preparation of this suspension.
    Type: Grant
    Filed: December 26, 1996
    Date of Patent: December 22, 1998
    Assignee: Kemira Agro Oy
    Inventors: Hannu Aijala, Thomas Ahlnas
  • Asiatic acid derivatives its manufacturing method and dermatological agent containing it
    Patent number: 5834437
    Abstract: The object of the present invention is to provide asiatic acid derivatives, its pharmaceutically acceptable salts or esters.Asiatic acid, its trisaccharide asiaticoside and mddecassic acid, extracted from Centella asiatica have been used for a long time in the management of skin scars and chronic ulcers. In this invention, asiatic acid derivatives synthesized from asiatic acid show excellent wound-healing properties.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: November 10, 1998
    Assignee: Dong Kook Pharmaceutical Co., Ltd.
    Inventors: Sang-Sup Jew, Hee-Doo Kim, Young-Hoon Jung, Eun-Hee Park, Sung-Ki Seo, Tae-Gyu Nam, Duc-Ky Hahn, Jae-Ho Park, Pil-Jong Sim, Min-Jung Lim, Kyung-Haw Lim
  • Solid protector against UV, process for its preparation and use thereof
    Patent number: 5811082
    Abstract: A less dusty, more stable and more easily handlable protector against UV light than previously is obtained by supplying it in the form of solid particles having a mean diameter of at minimum 10 .mu.m and containing, dispersed in 90-20 parts by weight of wax, 10-80 parts by weight of a pigment which reduces the penetration UV light and is made up of metal oxide particles of a mean primary particle diameter smaller than 0.150 .mu.m.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: September 22, 1998
    Assignee: Kemira Pigments Oy
    Inventors: John Thomas Ahlnas, Timo Valdemar Lofgren
  • Control scheme for rapid pulp delignification and bleaching
    Patent number: 5736004
    Abstract: A process control method for adjusting chemical application in response to the pulp brightness and/or lignin content is realized by utilizing a coupled control feedforward, feedback or combination feedforward/feedback control system, wherein brightness measurements are made between successive lignin content measurements and adjustments made to the chemical application in response to a comparison value.
    Type: Grant
    Filed: January 27, 1997
    Date of Patent: April 7, 1998
    Assignee: Union Camp Patent Holding, Inc.
    Inventors: George Pangalos, Ronald A. Falcone, Jr., William L. Mayo, Gregory J. Bosch
  • Menstrual detector
    Patent number: 5728125
    Abstract: A menstrual detector comprising a sanitary napkin of reduced dimensions, formed by a thin layer of absorbent material, and within the interior of the absorbent material a small cavity containing a temperature-sensitive reactive chemical product that can respond by turning cold when it comes into contact with and dissolves in a menstrual flow.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: March 17, 1998
    Inventor: Maria Teresa Echeverria Salinas