Abstract: This invention is directed to quinoline/quinoxaline compounds which inhibit platelet-derived growth factor tyrosine kinase and/or Lck tyrosine kinase, to pharmaceutical compositions comprising these compounds, and to the use of these compounds for treating a patient suffering from or subject to disorders/conditions involving cellular differentiation, proliferation, extracellular matrix production or mediator release and/or T cell activation and proliferation.

Abstract: A coupling for joining pipe segments together is disclosed. The coupling is derived from a standard fitting and has a housing with a socket and a first expanded region adjacent to the socket and a second expanded region adjacent to the first expanded region. A sealing member is positioned in the first expanded region, a retainer is positioned in the second expanded region and a support washer having transversely oriented radial and coaxial flanges is positioned adjacent to the retainer. A clamping tab turned inwardly on the second expanded region overlaps the radial flange and clamps the support washer and retainer against a shoulder within the second expanded region thereby also capturing the sealing member within the coupling. The retainer has a plurality of radial teeth angularly oriented to engage a pipe and prevent its removal from the coupling. The teeth are twisted about their longitudinal axes.

Abstract: A container having multiple wall panels forming container sides, the container having at least first and second wall panels that meet at a first corner. The container is assembleable from a flat or knockdown state to an opened or assembled state. A first inner panel is attached to a first wall panel, the first inner panel having an end spaced from the first corner. A slidable corner support is attached to the end of the first inner panel and extends towards the second wall panel. When the container is assembled from the knockdown state, the slidable corner support moves away from the first corner to form a support member that can help support a container stacked on top and prevent nesting.

Abstract: A preferred embodiment of a lifting device for a personal-transportation vehicle includes an arm for lifting the personal transportation vehicle, a column for supporting the arm, and a base for supporting and stabilizing the column. The base includes a bar pivotally coupled to the column and capable of being secured to a mounting surface.

Abstract: Image acquisition refers to the taking of digital images of multiple views of the object of interest. In the processing step, the constituent images collected in the image acquisition step are selected and further processed to form a multimedia sequence which allows for the interactive view of the object. Furthermore, during the Processing phase, the entire multimedia sequence is compressed and digitally signed to authorize it viewing. In the Storage and Caching Step, the resulting multimedia sequence is sent to a storage servers. In the Transmission and viewing step, a Viewer (individual) may request a particular multi-media sequence, for example, by selecting a particular hyperlink within a browser, which initiates the downloading, checking of authorization to view, decompression and interactive rendering of the multi-media sequence on the end-users terminal, which could be any one of a variety of devices, including a desktop PC, or a hand-held device.

Abstract: A preferred embodiment of a device for securing a personal-transport vehicle to a mounting surface includes one of a plow bracket and a bracket member for mounting on one of the personal-transport vehicle and the mounting surface, and a receptacle for mounting on the other of the personal transport vehicle and the mounting surface and for mating with and receiving the one of a plow bracket and a bracket member. The receptacle includes a panel and a docking lever pivotally coupled to the panel and movable between a first position wherein docking lever retains the one of a plow bracket and a bracket member so that the receptacle and the one of a plow bracket and a bracket member remain in a mated condition, and a second position.

Abstract: A method for identifying compounds that inhibit amyloidal-beta precursor protein processing in cells, comprising contacting a test compound with a GPCR polypeptide, or fragment thereof, and measuring a compound-GPCR property related to the production of amyloidal-beta peptide. Cellular assays of the method measure indicators including second messenger and/or amyloid beta peptide levels. Therapeutic methods,and pharmaceutical compositions including effective amyloidal-beta precursor processing-inhibiting amounts of GPCR expression inhibitors, are useful for treating conditions involving cognitive impairment such as Alzheimers Disease.

Abstract: A cutting element and chamfering tool for pipe preparation is disclosed. The cutting element is formed from a ring having a split defining ends of the ring. One of the ends has a cutting edge. The one end is offset from the other to present the cutting edge to the pipe end. The ring has an inwardly facing angularly oriented surface that receives and centers the pipe end. The chamfer is cut when the ring and pipe end are rotated relatively to one another. The tool has a housing that holds the cutting element. The ends of the ring are offset when the ring engages a helical seat within the housing and/or when a radial set screw engaging the one end is tightened.

Abstract: A system and method for localizing imaging devices in a network using images taken by the imaging devices. The relative position and orientation of a network of camera-equipped communications devices are obtained by having each device examine images taken by its camera. The devices are also equipped with controllable light sources that vary their output in a predetermined manner. This variation is found in images and used to identify the devices in view and to define epipolar points related to the other imaging devices in view. Common reference points in the image are also identified. The imaging devices then exchange details of the epipolar and common reference points with each other, and use them to obtain their relative position and orientation.

Abstract: A holding apparatus provided with a holding portion for holding a flange portion of an optical element. The holding portion includes a bearing surface block having a bearing surface, which contacts the flange portion, and a bearing surface block support mechanism, which rotatably supports the bearing surface block about a tangential axis of the optical element. This structure holds the optical element with the optical element holding apparatus in a kinematical manner and maintains satisfactory imaging performance in the optical element.

Abstract: A filter apparatus for improving gas temperature stability while maintaining a high impurity removal capacity. The filter apparatus includes a filter for removing impurities from a gas and a temperature adjuster for adjusting the temperature of the gas to a predetermined temperature. The filter apparatus further includes a humidity detector, arranged at the upstream side of the filter, for adjusting the humidity of the gas before the gas passes through the filter.

Abstract: The invention relates to pearlescent pigments with a platelet-shaped substrate comprising metal oxide and having a first and a second protective layer, said metal oxide having a refractive index of greater than 1.8, there being on the platelet-shaped substrate a first protective layer comprising cerium oxide and/or cerium hydroxide and a second protective layer of SiO2, applied to which is an organic chemical aftercoat comprising at least one silane having at least one functional bond group and at least one silane without a functional bond group, it being possible for metal oxide layers other than cerium oxide and SiO2 to be disposed between the first and the second protective layer. The invention further relates to a process for preparing these pigments, and to the use thereof.

Abstract: Disclosed are compositions for anchoring materials in or to concrete or masonry. The compositions preferably comprise alkylacrylate ester monomer and a copolymer of alkylacrylate ester and methacrylic acid monomers, and free-radical catalyst.

Abstract: A method for predicting the effectiveness of medication-based therapy in lowering average blood glucose levels in a diabetic patient is provided. This method may further comprise selectively recommending a medication-based therapy on the basis of the arithmetic average of the relative minima. A method for determining susceptibility to symptomatic hypoglycemia in a patient is provided. This method may further comprise selectively recommending a medication-based therapy on the basis of the arithmetic average of the relative minima. Provided also is a device for continuously monitoring blood glucose levels in a patient. The methods and device involve applying a Fourier approximation to blood glucose level data.