Patents Represented by Attorney Theodore O. Groeger
  • Patent number: 4563556
    Abstract: An internal combustion electrical circuit breaker comprising at least one: (a) insulating cylinder; (b) pair of electrical conductors penetrating the cylinder approximately perpendicular to its longitudinal axis at a distance from both cylinder's plane sides; (c) conducting hollow piston contacting the conductors and an insulating pipe at its open portion, which pipe extends within that axis and penetrates the cylinder's first plane side; (d) arcing chamber extending from that plane side to the conductors; (e) pair of arcing blades within the arcing chamber at a distance from the conductors, piston and pipe; (f) valves within the pipe and first plane side, communicating with the arcing chamber and hollow piston; (g) combustion chamber extending from the piston's closed portion to the cylinder's second plane side; and (h) ignition, gas injection and valve means within the plane side and communicating with the combustion chamber.
    Type: Grant
    Filed: March 28, 1984
    Date of Patent: January 7, 1986
    Inventor: Michel Goldstein
  • Patent number: 4562802
    Abstract: An internal combustion engine comprising at least one flexible cylinder or semicylinder (chamber) formed from (a) at least one flexible, rectangular sheet attached to a rotor, which in turn is connected to a rotatable shaft, and (b) a pair of parallel end plates contacting the sheet's end surfaces and the engine's housing, which plates contain inlet and exhaust ports (valves) for gases and/or liquids, fuel injectors and spark- or glowplugs as well, and the cylinder's volume is periodically varied by at least one roller contacting the flexible sheet's curved surface at radial distances smaller and up to the rotor's (or chamber's) radius, thereby forcing the gases out, or into the flexible cylinder or semicylinder via the ports, respectively.
    Type: Grant
    Filed: November 14, 1983
    Date of Patent: January 7, 1986
    Inventor: Theodore O. Groeger
  • Patent number: 4481792
    Abstract: A cheap, compact container for cold-storing beverage or food cans and/or bottles, comprising: (a) a pair of symmetrical, heat-insulating solid blocks with a plurality of semicylindrical indentations therein, spaced at a distance from each other and the boundaries of the blocks; (b) at least one heat-conducting solid foil continuously lining a part of the indentations in either block; (c) at least one heat-absorbing can within an indentation of either block; and (d) fastening means for connecting both blocks so that cylindrical chambers are maintained therein.
    Type: Grant
    Filed: October 21, 1983
    Date of Patent: November 13, 1984
    Inventors: Theodore C. Groeger, Theodore O. Groeger
  • Patent number: 4453508
    Abstract: A pumping or combustion engine having one to four cylindrical or semi-cylindrical chambers formed by at least one flexible sheet attached to a rotor, which sheet and/or rotor contact a plane, rigid plate at both sides thereof, containing inlet and exhaust ports for gases and/or liquids therein, which ports are opened and closed by the sheet, rotor, and/or spring-loaded check valves; and the volume of each chamber is varied when flexing the sheet by the reciprocal or rotational momentum of the rotor(s) alone, or its rotation along outer or inner, stationary or moveable, spring-loaded rigid cylinders (rollers).
    Type: Grant
    Filed: October 22, 1981
    Date of Patent: June 12, 1984
    Inventor: Theodore O. Groeger
  • Patent number: 4309423
    Abstract: 19-Oxygenated steroid compounds of the pregnane series of the formula I ##STR1## in which R.sup.1 represents a hydrogen atom, andR.sup.2 represents an .alpha.-oriented lower alkanoylthio group, orR.sup.1 and R.sup.2 together represent a carbon-carbon bond or an .alpha.-or .beta.-oriented methylene radical,R.sup.3 represents a free hydroxymethyl group or a hydroxymethyl group etherified by a lower alkyl or esterified by a lower alkanoyl; or represents a formyl group, a carboxyl group or a lower alkoxycarbonyl group, andR.sup.4 represents a hydrogen atom or the acyl radical Ac of a carboxylic acid,and corresponding 1,2-dehydro derivatives have valuable aldosterone-antagonizing properties with a minimum effect on sexual functions. As the compounds reduce the excessive sodium retention and potassium excretion induced by aldosterone, they are especially useful as the active ingredient in pharmaceutical preparations for alleviating diseases involving hyperaldosteronismus in man and other warm-blooded animals.
    Type: Grant
    Filed: February 8, 1980
    Date of Patent: January 5, 1982
    Assignee: Ciba-Geigy Corporation
    Inventor: Michel Biollaz
  • Patent number: 4264619
    Abstract: New .alpha.-(cyclic tert. aminophenyl)-aliphatic acids, e.g. those of the formula ##STR1## and functional derivatives thereof, are anti-inflammatory agents.
    Type: Grant
    Filed: November 21, 1978
    Date of Patent: April 28, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Richard W. J. Carney, George deStevens
  • Patent number: 4263455
    Abstract: The invention relates to novel ortho-aminoacetophenones of the formula I ##STR1## and their tautomers, in which Z is hydrogen, halogen, lower alkyl, cycloalkyl, lower alkoxy, trifluoromethyl, nitro or substituted or unsubstituted sulphamoyl, m is 1 or 2, R is hydrogen, aryl or lower alkyl, R.sub.1 is hydrogen or lower alkyl, R.sub.2 is lower alkyl, cycloalkyl, aryl, cycloalkyl-lower alkyl, aryl-lower alkyl or substituted or unsubstituted pyridyl, R.sub.
    Type: Grant
    Filed: September 27, 1979
    Date of Patent: April 21, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Pier G. Ferrini, Richard Goschke, Alfred Sallmann, Alberto Rossi
  • Patent number: 4261907
    Abstract: The process depicted, for example, by the formulae ##STR1## R=esterified hydroxy yields valuable intermediates in the manufacture of drugs.
    Type: Grant
    Filed: March 12, 1979
    Date of Patent: April 14, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Heinz W. Gschwend, Charles F. Huebner
  • Patent number: 4261985
    Abstract: An advantageous diuretic action by excretion of water, sodium and chloride ions, with reduced excretion of potassium ions, is effected by combined administration of a 19-oxygenated steroid compound of the pregnane series of the formula ##STR1## wherein R.sub.a represents a hydrogen atom, andR.sub.b represents an .alpha.-oriented lower alkanoylthio group, orR.sub.a and R.sub.b together represent a carbon-carbon bond or an .alpha.- or .beta.-oriented methylene radical,R represents a free hydroxymethyl group or a hydroxymethyl group etherified by a lower alkyl or esterified by a lower alkanoyl; or represents a carboxyl group or a lower alkoxycarbonyl group, andR.sup.2 represents a hydrogen atom or the acyl radical Ac of a carboxylic acid,as the aldosterone-antagonising component A on the one hand, and, on the other hand, of a conventional diuretic which is unspecific in respect of electrolyte excretion, e.g.
    Type: Grant
    Filed: November 14, 1979
    Date of Patent: April 14, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Michel Biollaz
  • Patent number: 4261990
    Abstract: N-(diphenylmethoxy-mono- or bicyclic-alkyleneiminoalkyl)-dicarboximides, e.g. those of the formula ##STR1## A=aliphatic or cycloaliphatic radical R,R'=H, alkyl, halogen or CF.sub.3R"=H or both are ethyleneq=2-4and salts thereof are antiallergics and antiasthmatics.
    Type: Grant
    Filed: March 9, 1979
    Date of Patent: April 14, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Robert M. Bowman
  • Patent number: 4260619
    Abstract: Secondary 2-aminoalkyl-5-pyridinols, e.g., those of the formula ##STR1## and acid addition salts thereof are cardioprotective, e.g., antiischemic agents.
    Type: Grant
    Filed: February 19, 1980
    Date of Patent: April 7, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Renat H. Mizzoni
  • Patent number: 4260620
    Abstract: 5-Etherified 2-pyridinecarboxylic acids, e.g. those of the formula ##STR1## or functional derivatives thereof, are hypotensive agents.
    Type: Grant
    Filed: October 26, 1979
    Date of Patent: April 7, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Neville Finch, Renat H. Mizzoni
  • Patent number: 4259338
    Abstract: The present invention provides new benzofuranyl-tetrahydropyridines and -piperidines of the general formula I ##STR1## in which R.sub.1 and R.sub.2 independently of one another are hydrogen or lower alkyl or together are lower alkylene, R.sub.3 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, cyclo-lower alkyl or cyclo-lower alkyl-lower alkyl and Y.sub.1 and Y.sub.2 are each hydrogen or together are an additional bond, and the ring A is not further substituted or is further substituted by lower alkyl, lower alkoxy, halogen with an atomic number not more than 35, cyano or hydroxyl and the pharmaceutically acceptable acid addition salts thereof, and antidepressant preparations containing these compounds. The compounds according to the invention have valuable pharmacological properties.
    Type: Grant
    Filed: April 14, 1980
    Date of Patent: March 31, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Romeo Paioni, Walter Schilling, Raymond Bernasconi
  • Patent number: 4256759
    Abstract: 1-Substituted-.beta.-oxo-.alpha.-phenylcarbamoyl-pyrrolpropionitriles, e.g. those of the formula ##STR1## their alkylenol ethers or alkanoylenol esters and salts thereof are antiinflammatory and antiarthritic agents.
    Type: Grant
    Filed: April 21, 1980
    Date of Patent: March 17, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Gordon N. Walker
  • Patent number: 4255438
    Abstract: Pharmaceutical compositions comprising a substituted pyrazolidine-3,5-dione, e.g. the 1,2-diphenyl-4-(2-phenylthioethyl or 2-phenylsulfinylethyl)-pyrazolidine-3,5-dione, or a salt thereof with a base, are useful in the treatment of cardiovascular diseases.
    Type: Grant
    Filed: May 7, 1979
    Date of Patent: March 10, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Sydney H. Kane, Erwin Margulies
  • Patent number: 4255429
    Abstract: N-[1-(4-amino-2-quinazolinyl)-3- or 4-piperidinyl]-lactams, e.g., those of the formula ##STR1## and salts thereof are antihypertensive agents.
    Type: Grant
    Filed: January 28, 1980
    Date of Patent: March 10, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Lincoln H. Werner
  • Patent number: 4250192
    Abstract: Phenylacetic acid amide compounds of the formula ##STR1## in which R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.2 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.3 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35 and R.sub.4 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35, and in which R.sub.5 is a radical of aliphatic character containing the group R.sub.6, R.sub.6 and R.sub.7 are each hydrogen or together are a divalent alipahtic radical and the group of the formula --C(.dbd.O)--R.sub.8 (Ia) is a carboxyl group, which can be functionally modified, and their salts are useful as anti-inflammatory agents.
    Type: Grant
    Filed: April 25, 1979
    Date of Patent: February 10, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Alfred Sallmann, Gerhard Baschang
  • Patent number: 4242347
    Abstract: 1-(Indolyl-3-alkyl)-3 or 4-(ureido or guanidino)-piperidines, e.g. those of the formula ##STR1## R=H; alkyl; free, etherified or esterified OH or SH; CF.sub.3, NO.sub.2 or NH.sub.2m=1-4;n=2 or 3;X=O, S or NHacyl derivatives and salts thereof are antihypertensive agents.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: December 30, 1980
    Assignee: Ciba-Geigy Corporation
    Inventor: Charles F. Huebner
  • Patent number: 4226998
    Abstract: 2,3-Dihydro-1-benzothiepin-4-carboxamides, e.g. those of the formula ##STR1## Am=arylamino or N-alkyl-N-arylamino substituted by R X=HO, alkoxy, alkanoyloxy or alkyleneiminoR=alkyl, alkoxy, alkylmercapto, halo, CF.sub.3, CN, or NO.sub.2n=0-2or their salts with therapeutically useful bases, exhibit anti-inflammatory effects.
    Type: Grant
    Filed: September 20, 1978
    Date of Patent: October 7, 1980
    Assignee: Ciba-Geigy Corporation
    Inventor: Melvin H. Rosen
  • Patent number: 4221786
    Abstract: The invention relates to the preparation of polyhalogenated pregnane derivatives of the formula ##STR1## wherein X represents fluorine or chlorine and R a free or esterified hydroxyl group or chlorine. The new compounds display a high antiinflammatory activity. No side action on the thymus, the body weight or the adrenals can be detected at the therapeutic dose when the compounds are administered topically. The new compounds are therefore particularly suitable for use as medicaments in dermatology.The new compounds can be prepared according to methods known in the art, e.g. by introducing the chlorine atom in 2-position of corresponding compounds which are non chlorinated in this position, or by the introduction of the halogen atom in 9-position starting from the 9,11.beta.-epoxide or the 9,11-dehydro-compound or by acetonization of the 16,17-dihydroxy group or by replacing a 21-hydroxy group by chlorine.
    Type: Grant
    Filed: June 20, 1978
    Date of Patent: September 9, 1980
    Assignee: Ciba-Geigy Corporation
    Inventor: Jaroslav Kalvoda