Patents Represented by Attorney Theodore R. Furman

Find this attorney in the Justia Lawyer Directory

  • Sustained release alginate fibre and process for the preparation thereof
    Patent number: 5690955
    Abstract: An alginate fibre is provided which includes one or more medicaments incorporated into the fibre core such that the one or more medicaments can be released in a sustained manner over time and, optionally, one or more medicaments attached to the surface of the fibre whereby the one or more medicaments attached to the surface of the fibre can be released rapidly therefrom.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: November 25, 1997
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Bryan Griffiths, Pter Michael John Mahoney
  • Prophylactic and therapeutic treatment of skin sensitization and irritation
    Patent number: 5686100
    Abstract: Methods and devices for preventing and/or treating an adverse reaction of the skin to the presence of a skin-sensitizing and/or skin-irritating agent by administering an effective amount of a loop diuretic alone or in combination with at least one mast cell degranulator or at least one glucocorticosteroid.
    Type: Grant
    Filed: October 19, 1995
    Date of Patent: November 11, 1997
    Assignee: E.R. Squibb & Sons, Inc.
    Inventors: John J. Wille, Agis Kydonieus
  • Polymeric support wound dressing
    Patent number: 5681579
    Abstract: In accordance with the present invention a novel wound dressing providing superior absorption and preventing leakage is disclosed. The present dressing comprises a hydrocolloid-containing polymeric support layer either continuous or non-continuous and an occlusive backing layer overlying the support. In a preferred embodiment the present dressing further includes an adhesive on a skin-contacting surface of the support and an absorbent region interposed between the support and the backing layer.
    Type: Grant
    Filed: February 23, 1994
    Date of Patent: October 28, 1997
    Assignee: E.R. Squibb & Sons, Inc.
    Inventor: Frank Freeman
  • Wound hydrating gel with novel preservative system and low cytotoxicity
    Patent number: 5670169
    Abstract: The present invention relates to a preserved, yet non-cytotoxic alginate based hydrating gel system for the purpose of treating wounds that need moisture. Sodium carboxymethylcellulose and an alginate polymer blend impart sufficient viscosity to an aqueous solution to provide moisture to the wound. The blend reduces the cytotoxicity of a combination of preservatives incorporated into the system. More specifically, the invention relates to a wound hydrating gel comprising a) a hydrocolloid mixture of carboxymethylcellulose and sodium/calcium alginate, and b) a preservative system. This invention further relates to methods of preparing and using the wound hydrating gel.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: September 23, 1997
    Assignee: E.R. Squibb & Sons, Inc.
    Inventors: Marc D. Cornell, Nancy E. Kaiser, Rita A. Brenden
  • Cardiopulmonary bypass and organ transplant using a potassium channel activator
    Patent number: 5643921
    Abstract: In accordance with the present invention novel methods for cardiopulmonary bypass and organ transplant, each employing a potassium channel activator, are disclosed. The use of a potassium channel activator has been found to reduce the damage or ischemia induced by the bypass and transplant procedures.
    Type: Grant
    Filed: September 26, 1990
    Date of Patent: July 1, 1997
    Assignee: E.R. Squibb & Sons, Inc.
    Inventor: Gary J. Grover
  • Prophylactic treatment of allergic contact dermatitis
    Patent number: 5618557
    Abstract: Methods and devices for preventing an adverse reaction of the skin to the presence of a skin-sensitizing agent by administering an effective amount of a potassium-sparing diuretic.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: April 8, 1997
    Assignee: E.R. Squibb & Sons, Inc.
    Inventors: John J. Wille, Agis Kydonieus, Frank S. Castellana
  • Fibrin sealant applicatoor
    Patent number: 5605541
    Abstract: A novel device and method for the application of two or more components of a fibrin sealant using a gas is disclosed. The novel device and method involve the concentric arrangement of annular apertures for each of the components concentric with and radially outward of a center gas discharge aperture in the exit end of a spray head. Reservoirs for each component, for example syringe cartridges or cylinders, are in dextrete fluid communication with the spray head and preferably can be activated by a common means.
    Type: Grant
    Filed: December 8, 1994
    Date of Patent: February 25, 1997
    Assignee: E. R. Squibb and Sons, Inc.
    Inventor: Niels-Erik Holm
  • Wound dressing
    Patent number: 5603946
    Abstract: A novel two piece dressing having a baseplate and wound fluid absorbing material is provided according to the present invention. The baseplate is provided with slits or incisions for covering, examining and/or treating the wound without removing the baseplate. The dressing contains an absorbent material designed to remove excess exudate from the wound through an aperture in the baseplate. The incisions or slits may, in one embodiment, extend from the aperture and define one or more flaps for viewing and/or treating the wound.
    Type: Grant
    Filed: October 8, 1993
    Date of Patent: February 18, 1997
    Assignee: Bristol-Myers Squibb Company
    Inventor: Barry Constantine
  • Liquid separation apparatus and method
    Patent number: 5603845
    Abstract: In a process of separating a liquid sample having phase portions of different densities by centrifugal separation, a phase separator container is employed. The phase separator container comprises a housing having concentric inner and outer cylindrical walls defining a longitudinal axis and a top wall and further a piston body constituting a bottom wall of the housing. The piston body defines together with the outer cylindrical wall, the inner cylindrical wall and the top wall, an annular chamber for receiving the liquid sample. The piston body is displaceable within the annular chamber for draining a phase portion separated from the liquid sample through a drain conduit means communicating with the annular chamber. The phase separation chamber further comprises a reaction chamber to which the phase portions exposed from the annular chamber is processed.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: February 18, 1997
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Niels E. Holm
  • Medical dressing with semi-peripheral delivery system
    Patent number: 5599289
    Abstract: In accordance with the present invention novel medical dressing systems and methods are disclosed using a semiperipheral support design which provides at least one conformal, unsupported dressing edge upon application. The dressing system disclosed herein comprises a backing layer, an adhesive material overlying the backing layer and a release liner overlying the adhesive, wherein said medical dressing system further comprises a final dressing portion and a semiperipheral support portion partially surrounding said dressing portion and said support portion being partially defined by a separation, said dressing portion being further defined by at least one unsupported edge, said one or more unsupported edges extending from a first end to a second end of said semiperipheral support portion.
    Type: Grant
    Filed: January 4, 1995
    Date of Patent: February 4, 1997
    Assignee: Bristol-Myers Squibb Co.
    Inventor: Frank S. Castellana
  • Polyurethane pressure-sensitive adhesives
    Patent number: 5591820
    Abstract: Pressure-sensitive adhesives which possess absorptivity and/or permeability properties to remove transepidermal water loss and/or other bodily fluids that come into contact with the adhesive, in combination with a fine balance of cohesion and adhesion properties, can be formulated by controlling the crosslinking of a polyurethane polymer having excess hydroxyl functionality, a glass transition temperature of less than about 0.degree. C., a moisture absorption of at least about 20% of its weight and/or a moisture vapor transmission rate of at least about 300 grams/meter.sup.2 /24 hours measured at 37.degree. C. and a 90% relative humidity gradient. Adhesives of these polymers possess a peel adhesion to human skin of between about 0.3 and 4 newtons/cm width of the polymer or adhesive.
    Type: Grant
    Filed: May 9, 1995
    Date of Patent: January 7, 1997
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Agis Kydonieus, Ladislav Bastar, Kishore Shah, Khosrow Jamshidi, Tak-lung Chang, Sheng-hung Kuo
  • Temperature activated controlled release
    Patent number: 5580573
    Abstract: A polymeric device for the controlled release of active agents contained in the device in which the polymer has a glass transition temperature greater than the normal storage or non use temperature of the device. When heated to or above the glass transition temperature of the polymer, the active agent is released. The release of active agent can be switched on or off by the adjustment of the temperature of the polymeric device above or below the glass transition temperature of the polymer.
    Type: Grant
    Filed: July 7, 1993
    Date of Patent: December 3, 1996
    Assignee: E. R. Squibb and Sons, Inc.
    Inventors: Agis Kydonieus, Kishore R. Shah, Stefanie C. Decker
  • Substituted cyanoimino benzopyranes
    Patent number: 5563170
    Abstract: Novel compounds are disclosed having the formula ##STR1## and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are as defined herein. These compounds are useful, for example, as cardiovascular agents and especially as anti-ischemic agents.
    Type: Grant
    Filed: August 15, 1991
    Date of Patent: October 8, 1996
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Karnail Atwal
  • Thermoplastic hydrogel impregnated composite material
    Patent number: 5527271
    Abstract: A composite material for wound dressings having a fibrous wound-contacting substrate, such as cotton gauze, impregnated with a thermoplastic hydrogel forming polymer and methods of making the same.
    Type: Grant
    Filed: March 30, 1994
    Date of Patent: June 18, 1996
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Kishore R. Shah, Agis Kydonieus, Khosrow Jamshidi, Stefanie C. Decker, Tak-lung Chang
  • Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline
    Patent number: 5514690
    Abstract: Novel compounds having potassium channel activating activity and useful, for example, as antiischemic agents are disclosed. These compounds have the general formula ##STR1## wherein A is ##STR2## or a single bond to complete an indoline nucleus; X is --O--, --S-- or --NCN; and the R groups are as defined herein.
    Type: Grant
    Filed: August 24, 1993
    Date of Patent: May 7, 1996
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Karnail S. Atwal, Francis N. Ferrara
  • Hydrocolloid wound gel
    Patent number: 5503847
    Abstract: A hydrocolloid wound gel composition useful for cleansing an debriding wounds and having some capacity for absorbing wound exudate and a method of treating wounds comprising applying the hydrocolloid wound gel to a wound.The composition includes sodium carboxymethylcellulose, pectin, propylene glycol and water.
    Type: Grant
    Filed: April 15, 1993
    Date of Patent: April 2, 1996
    Assignee: E. R. Squibb and Sons, Inc.
    Inventors: Douglas Queen, Lesley A. Chambers, Simon M. Adams, Hugh Delargy
  • Combined two stage method for cleaning and decontaminating surgical instruments
    Patent number: 5489531
    Abstract: A two stage method using the same container for both cleaning and microbiologically decontaminating grossly soiled surgical instruments is described. A presoak in an enzyme solution is followed by direct addition of a compatible disinfectant and a continued soak to decontaminate surgical instruments and other paraphernalia used in healthcare facilities.
    Type: Grant
    Filed: July 24, 1992
    Date of Patent: February 6, 1996
    Assignee: E. R. Squibb and Sons, Inc.
    Inventor: Leslee M. Benson
  • Dihydropyrimidine derivatives
    Patent number: 5470975
    Abstract: Novel A-II receptor antagonists have the formula ##STR1## and its isomer ##STR2## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are as defined herein.
    Type: Grant
    Filed: January 11, 1994
    Date of Patent: November 28, 1995
    Assignee: E.R. Squibb & Sons, Inc.
    Inventor: Karnail Atwal
  • Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
    Patent number: 5466817
    Abstract: A new method for the treatment of ischemia conditions and arrhythmia is disclosed. The method uses compounds of the formula ##STR1## wherein A can be --CH.sub.2 --, --O--, --NR.sub.9 --, --S--, --SO--, --SO.sub.2 --; X can be oxygen or sulfur; Y can be --NR.sub.8, --O--, --S--, --CH.sub.2 -- and the R groups are as defined herein. Novel compounds within the definition of formula I are also disclosed.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: November 14, 1995
    Assignee: E.R. Squibb & Sons, Inc.
    Inventor: Karnail Atwal
  • Dispenser for tissue glue
    Patent number: D369657
    Type: Grant
    Filed: March 30, 1993
    Date of Patent: May 7, 1996
    Assignee: Bristol-Myers Squibb Co.
    Inventor: Steve McGugan