Abstract: The present invention provides compositions of matter comprising a polypeptide expressed from insect cells harboring a baculovirus vector the encodes the polypeptide, wherein the polypeptide comprises amino acid sequences derived from the p42 fragment of the Plasmodium falciparum gp 195 protein or derivatives thereof. Such compositions of matter find use for example for inducing the production of anti-p42 antibodies both in vivo and in vitro.
February 14, 1994
Date of Patent:
July 16, 2002
University of Hawaii
Sandra Chang, George S. N. Hui, Philip J. Barr, Helen Gibson