Patents Represented by Attorney Viksnins Harris & Padys PLLP
  • Patent number: 8348676
    Abstract: A method includes opening an access member of a sensing assembly to access programming features of the sensing assembly. Operating instructions for the sensing assembly are selected, and then a teaching actuator is actuated. The method further includes indicating the teaching actuator has been actuated, such as by visually indicating with an LED, and ceasing the indication. The method further includes implementing the operating instructions if the teaching actuator is released within a predetermined time period from cessation of the indication.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: January 8, 2013
    Assignee: Rockwell Automation Technologies, Inc.
    Inventors: Rudolf Engl, Helmut Pall, Reinhard Schwarz
  • Patent number: 8337774
    Abstract: Disclosed are compositions and methods useful for the rapid and facile simultaneous detection of malodorous bacterial metabolites in samples of expired breath and other fluids. The invention enables estimation, by simple visual inspection and comparison against standards, of the concentration of polyamines and volatile sulfur compounds in the micromolar to millimolar range.
    Type: Grant
    Filed: December 11, 2006
    Date of Patent: December 25, 2012
    Assignee: ALT BioScience, LLC
    Inventors: James C. Pendergrass, Boyd E. Haley
  • Patent number: 8338452
    Abstract: Compounds of Formula (I) are useful for inhibition of Raf kinases. Methods of using compounds of Formula (I) and stereoisomers, tautomers, prodrugs and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: December 25, 2012
    Assignees: Array BioPharma Inc., Genentech, Inc.
    Inventors: Kateri A. Ahrendt, Alexandre J. Buckmelter, Jonas Grina, Joshua D. Hansen, Ellen R. Laird, David Moreno, Brad Newhouse, Li Ren, Steven M. Wenglowsky, Bainian Feng, Janet Gunzner, Kim Malesky, Simon Mathieu, Joachim Rudolph, Zhaoyang Wen, Wendy B. Young
  • Patent number: 8328933
    Abstract: The invention provides a method to enforce face-to-face stacking of organic semiconductors in the solid state that employs semiconductor co-crystal formers (SCCFs), to align semiconductor building blocks (SBBs). Single-crystal X-ray analysis reveals ?-orbital overlap optimal for organic semiconductor device applications.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: December 11, 2012
    Assignee: University of Iowa Research Foundation
    Inventors: Leonard R. MacGillivray, Anatoliy N. Sokolov
  • Patent number: 8329701
    Abstract: The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula (I): Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: December 11, 2012
    Assignee: Array Biopharma Inc.
    Inventors: Ian S. Mitchell, James F. Blake, Rui Xu, Nicholas C. Kallan, Dengming Xiao, Keith Lee Spencer, Josef R. Bencsik
  • Patent number: 8329890
    Abstract: The present invention is directed to small interfering RNA molecules (siRNA) targeted against an allele of interest, and methods of using these siRNA molecules.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: December 11, 2012
    Assignee: University of Iowa Research Foundation
    Inventors: Beverly L. Davidson, Henry Paulson, Victor Miller, Cynthia Gouvion
  • Patent number: 8329709
    Abstract: Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: December 11, 2012
    Assignees: Genentech, Inc., Array BioPharma Inc.
    Inventors: Anna L. Banka, Josef R. Bencsik, James Blake, Martin Hentemann, Nicholas C. Kallan, Jun Liang, Ian S. Mitchell, Stephen T. Schlachter, Eli M. Wallace, Rui Xu, Tony P. Tang
  • Patent number: 8324221
    Abstract: The present invention provides compounds of Formula (I) including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: December 4, 2012
    Assignee: Array Biopharma Inc.
    Inventors: Anna L. Banka, James F. Blake, Josef R. Bencsik, Kin Chiu Fong, Martin F. Hentemann, Douglas M. Sammond, Ian S. Mitchell, Rui Xu, Eli M. Wallace, Tony Tang
  • Patent number: 8324206
    Abstract: A thienopyrimidine of formula (I): and the pharmaceutically acceptable salts thereof have activity as inhibitors of PI3K with selectivity for the P110? subtype, and may be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour, particularly those associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: December 4, 2012
    Assignee: F. Hoffmann-La Roche AG
    Inventors: Irina Chuckowree, Adrian Folkes, Tim Hancox, Stephen Shuttleworth
  • Patent number: 8324244
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: December 4, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Eric Dowdy, Xi Chen, Steven Pfeiffer
  • Patent number: 8324257
    Abstract: This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment of various disorders.
    Type: Grant
    Filed: October 3, 2007
    Date of Patent: December 4, 2012
    Assignee: Array Biopharma Inc.
    Inventors: Kateri Ahrendt, Robert Kirk Delisle, Jeremy Hans, Joseph P. Lyssikatos, John E. Robinson, Eli M. Wallace, Qian Zhao
  • Patent number: 8316674
    Abstract: A lock (10) which includes a body and an actuator (36) which is pivotally displaceable between a rest position and a displaced position. The lock further includes a first member (64) which is longitudinally displaceable by the actuator (36) and a second 5 member (66) which is longitudinally in register with the first member (64) and longitudinally displaceable relative to the body and the first member (64). The lock includes bias means (90) biasing the first and second members (64, 66) away from one another. The lock further includes retaining means (98) which is displaceable from a locked position, in which it inhibits displacement of the second member (66) and a 10 released position in which it permits displacement of the second member (66).
    Type: Grant
    Filed: March 10, 2009
    Date of Patent: November 27, 2012
    Inventor: Piotr Leonard Kowalczyk
  • Patent number: 8309070
    Abstract: The invention relates generally to methods for isolation and culture of umbilical cord blood stem cells, cells isolated by the methods, and therapeutic uses for those cells.
    Type: Grant
    Filed: May 17, 2005
    Date of Patent: November 13, 2012
    Assignee: Regents of the University of Minnesota
    Inventors: Walter Low, Jing Xiao, Zhenhong Nan
  • Patent number: 8309071
    Abstract: The present invention concerns the technical field of nucleic acids and expression-optimized nucleic acids. The present invention concerns especially nucleic acids comprising a mutated foamy viral envelope gene encoding a foamy viral envelope polypeptide, which comprises a leader peptide (LP), a surface unit (SU) and a transmembrane domain (TM). The present invention also relates to modified polypeptides encoded by these nucleic acids. Furthermore, the present invention regards a method for preparing pseudotyped vector particles as well as a method for treating a genetic disorder comprising administering a nucleic acid or a polypeptide encoded by that nucleic acid.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: November 13, 2012
    Assignee: Vectoria Forschungsforderungs Verein E.V.
    Inventors: Dirk Lindemann, Kristin Stirnnagel, Daniel Lueftenegger
  • Patent number: 8299215
    Abstract: The present disclosure provides targeting peptides and vectors containing a sequence that encodes targeting peptides that deliver agents to the brain.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: October 30, 2012
    Assignee: University of Iowa Research Foundation
    Inventors: Beverly L. Davidson, Yong Hong Chen
  • Patent number: 8299076
    Abstract: Disclosed are crystalline forms of 2-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: October 30, 2012
    Assignees: Array Biopharma Inc., Astrazeneca AB
    Inventors: Allison L. Marlow, Eli Wallace, Jeongbeob Seo, Joseph P. Lyssikatos, Hong Woon Yang, Jim Blake, Richard Anthony Storey, Rebecca Jane Booth, John David Pittam, John Leonard, Mark Richard Fielding
  • Patent number: 8287530
    Abstract: The invention features compact apparatuses useful in electrosurgery. The compact apparatuses have a housing having a cavity, an electrosurgical system located within the cavity, the electrosurgical system having optionally a monopolar output system, optionally a bipolar output system, optionally an argon plasma coagulation output system, a processor located within the cavity, the processor operatively coupled to each output system of the electrosurgical system to control outputs generated by each output system, optionally a high frequency generator located within the cavity and operatively coupled to the processor; and a gas canister holder and control system located within the cavity of the housing for receiving a gas canister within the cavity of the housing.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: October 16, 2012
    Assignee: Genii, Inc.
    Inventor: Marcia L. Morris
  • Patent number: 8273341
    Abstract: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: November 8, 2011
    Date of Patent: September 25, 2012
    Assignee: Gilead Sciences, Inc.
    Inventors: Hongyan Guo, Darryl Kato, Thorsten A. Kirschberg, Hongtao Liu, John O. Link, Michael L. Mitchell, Jay P. Parrish, Michael Graupe, Jianyu Sun, James Taylor, Elizabeth M. Bacon, Eda Canales, Aesop Cho, Choung U. Kim, Jeromy J. Cottell, Manoj C. Desai, Randall L. Halcomb, Evan S. Krygowski, Scott E. Lazerwith, Qi Liu, Richard Mackman, Hyung-Jun Pyun, Joseph H. Saugier, James D. Trenkle, Winston C. Tse, Randall W. Vivian, Scott D. Schroeder, William J. Watkins, Lianhong Xu
  • Patent number: 8268852
    Abstract: Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8, R9, W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: January 20, 2009
    Date of Patent: September 18, 2012
    Assignee: Array BioPharma Inc.
    Inventors: James F. Blake, Joseph P. Lyssikatos, Hong-Woon Yang, Eli M. Wallace, Jeongbeob Seo
  • Patent number: 8263810
    Abstract: The invention provides methods for storing boranes (e.g. B-allyldiisopinocampheylborane). The invention also provides stable compositions comprising boranes, as well as methods for carrying out allylboration at high temperature and/or in the presence of water.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: September 11, 2012
    Assignees: Regents of the University of Minnesota, Sigma-Aldrich Co. LLC
    Inventors: Venkatram R. MeReddy, Kanth V. B. Josyula