Patents Represented by Attorney William Fish & Richardson McGowan

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  • Needle-less parenteral introduction device
    Patent number: 6120786
    Abstract: A needle-less device for the parenteral administration of a medicament is disclosed. The medicament has the shape of one end of a toothpick. It is placed in the bore of a barrel with the barrel having the shape of a nose cone at one end. A plunger is inserted into the other end of the bore. The plunger forces the medicament through the skin and into subcutaneous layer of the patient without the need for the penetration of the skin by a needle.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: September 19, 2000
    Assignee: Delab
    Inventor: Roland Cherif Cheikh
  • Sustained release drug formulations
    Patent number: 5980945
    Abstract: A sustained release drug formulation including: a drug; a biodegradable polymer which is insoluble in water; and an oil vehicle in which both the drug and the polymer are dissolved. The oil vehicle contains 10-100% by volume a pharmaceutically acceptable oil and 0-90% by volume a pharmaceutically acceptable liquid carrier for the drug or the polymer.
    Type: Grant
    Filed: January 16, 1996
    Date of Patent: November 9, 1999
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifique S.A.
    Inventor: Jean-Marc Ruiz
  • Neuroprotective pharmaceutical composition containing stereoisomers of arylcyclohexylamines
    Patent number: 5972952
    Abstract: The invention relates to pharmaceutical compositions for neuroprotection containing the compound (1S,2R) 1-[1-(2-thienyl)-2-alkylcyclohexyl]piperidine or (1S,2R) 1-[1-(2-furanyl)-2-alkylcyclohexyl]piperdine, or their pharmaceutically acceptable salts. The synthesis and method separation of racemic mixtures to provide pure enantiomers is presented. The compositions have use in the treatment of stroke, CNS trauma and Alzheimer's disease.
    Type: Grant
    Filed: December 10, 1996
    Date of Patent: October 26, 1999
    Assignee: Le Centre National De La Recherche Scientifique
    Inventors: Jean-Marc Kamenka, Martine Michaud, Marie-Jeanne Drian, Jacques Vignon, Alain Privat
  • Analogs of parathyroid hormone
    Patent number: 5955574
    Abstract: Peptide variants of fragment of parathyroid hormone (PTH) or parathyroid hormone-related protein (PTHrP), in which at least one of the amino acid residues is replaced with Acc.
    Type: Grant
    Filed: March 7, 1997
    Date of Patent: September 21, 1999
    Assignee: Societe De Conseils De Recherches Et D'Applications Scientifiques, S.A.
    Inventor: Zheng Xin Dong
  • Acylated cyclodextrin derivatives
    Patent number: 5916883
    Abstract: A cyclodextrin derivative, wherein at least 60 percent of the free hydroxy groups of said cyclodextrin are acylated with acyl groups where at least one of said acyl groups comprise a free carboxylic group.
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: June 29, 1999
    Assignee: Poly-Med, Inc.
    Inventors: Shalaby W. Shalaby, Joel Thomas Corbett
  • Transgenic mouse containing an IGF-1 transgene
    Patent number: 5837875
    Abstract: A transgenic mouse containing an IGF-1 transgene which is operably linked to a promoter sequence and is expressed in the pancreas of the mouse.
    Type: Grant
    Filed: December 26, 1995
    Date of Patent: November 17, 1998
    Assignee: The Autonomous University of Barcelona
    Inventors: Fatima Bosch, Alfons Valera
  • Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
    Patent number: 5821221
    Abstract: A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
    Type: Grant
    Filed: September 9, 1997
    Date of Patent: October 13, 1998
    Assignee: Biomeasure, Incorporated
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Francis Ignatious, Jacques-Pierre Moreau