Patents Represented by Attorney Wilmer Cutler Pickering Hale and Dorr LLP
  • Patent number: 8304181
    Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions. The present application describes a method for using lactate measurement in the arterial and the venous blood lines of the Organ Care System Heart perfusion device to evaluate the: 1) The overall perfusion status of an isolated heart and 2) The metabolic status of an isolated heart and 3) the overall vascular patency of an isolated donor heart. This aspect of the present invention uses the property of myocardial cell's unique ability to produce/generate lactate when they are starved for oxygen and metabolize/utilize lactate for energy production when they are well perfused with oxygen.
    Type: Grant
    Filed: April 25, 2007
    Date of Patent: November 6, 2012
    Assignee: Transmedics, Inc.
    Inventors: Waleed Hassanein, Tamer Khayal, Ahmed Elbetanony, Paul Lezberg, Giovanni Cecere, Dennis Sousa, Elizabeth Hansen
  • Patent number: 8304409
    Abstract: The invention describes novel nitrosated nonsteroidal antiinflammatory drugs (NSAIDs) and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated NSAID, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one nitrosated NSAID, and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one nitrosated NSAID, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: November 6, 2012
    Assignee: Nicox S.A.
    Inventors: Richard A. Earl, Maiko Ezawa, Xinqin Fang, David S. Garvey, Ricky D. Gaston, Subhash P. Khanapure, L. Gordon Letts, Chia-En Lin, Ramani R. Ranatunge, Stewart K. Richardson, Joseph D. Schroeder, Cheri A. Stevenson, Shiow-Jyi Wey
  • Patent number: 8305775
    Abstract: During a soft start period at the time of startup, a PWM control is carried out. After the soft start period ends, the PWM control is converted into a frequency control, so that stress of a switching element is suppressed and the audible oscillation frequency is removed. As a result, it is possible to obtain a switching power supply device having high power conversion efficiency.
    Type: Grant
    Filed: September 22, 2010
    Date of Patent: November 6, 2012
    Assignee: Sanken Electric Co., Ltd.
    Inventor: Masaaki Shimada
  • Patent number: 8301800
    Abstract: Techniques for representation of data representations associated with message processing are disclosed. The techniques can be used to implement a message server operating in a distributed computing environment. The message server provides a flexible environment which is better suited for creation and maintenance of message processing representations used to exchange messages between various nodes in the distributed computing environment. In addition, the message server is also capable of generating pre-computed data suitable for runtime processing of messages. The pre-computed data can be used to improve runtime processing of messages. As result, many problems associated with message processing in conventional distributed computing environments can be addressed.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: October 30, 2012
    Assignee: Actional Corporation
    Inventor: Kerry Champion
  • Patent number: 8301531
    Abstract: A manually-assisted computer and communications apparatus is provided for periodically fixing a price of a currency or commodity. Successive rate samples of said currency/stock/commodity are received from a plurality of sources (80) over a period of time, recorded and filtered automatically (90) by reference to said historical record and predetermined validation criteria so as to categorize certain samples as valid or erroneous. The received & filtered samples are combined periodically (105-115) so as to derive a fixed rate, which is then released (120) to users. The filtering means distinguishes between rate samples of different contributors within the samples received from a given source, and also receives (OTR1) trading rates generated by an online trading system, in addition to rates quoted by other contributors. Trading rates are applied in said fixed rate in preference to quoted rates.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: October 30, 2012
    Assignee: The World Markets Company PLC
    Inventor: Brian T. Dawson
  • Patent number: 8299944
    Abstract: Systems and methods are disclosed for storing deduplicated images in which a portion of the image is stored in encoded form directly in a hash table, the method comprising: organizing unique content of each data object as a plurality of content segments and storing the content segments in a data store; receiving content to be included in the deduplicated image of the data object; determining if the received content may be encoded using a predefined non-lossy encoding technique and in which the encoded value would fit within the field for containing a hash signature; if so, placing the encoding in the field and marking the hash structure to indicate that the field contains encoded content; otherwise, generating a hash signature for the received content and placing the hash signature in the field and placing the received content in a corresponding content segment if it is unique.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: October 30, 2012
    Assignee: Actifio, Inc.
    Inventor: Christopher A. Provenzano
  • Patent number: 8300603
    Abstract: Location reporting in long term evolution (LTE) wireless networks is provided. Systems and methods are disclosed to provide support of location reporting and messaging at a mobility management entity (MME) to allow location updates to serving gateways (SGWs) and packet data network gateways (PGWs), and for the SGWs and PGWs to activate and de-activate location reporting. The MME also supports detection and communication with the LTE radio access network to provide location reporting back to the communication network. The MME and the accompanying messaging can provide location reporting including enhanced cell global identity (ECGI) and tracking area identity (TAI) information.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: October 30, 2012
    Assignee: Cisco Technology, Inc.
    Inventors: Kuntal Chowdhury, Rajesh Ramankutty
  • Patent number: 8300629
    Abstract: Systems and methods for providing interaction management to network devices in a communication network are described. A gateway may be used to implement the interaction capabilities on packet flows for IP multimedia subsystem (IMS) and multimedia domain (MMD) architectures. Interaction managers and proxy agents can be provided by the gateway, such as a service control interaction manager (SCIM). The SCIM can be a layer and manage interactions between network devices such as mobile nodes and application servers and can provide abstraction of network devices. This can allow the gateway to provide interworking between network devices and handle mobile nodes with different capabilities.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: October 30, 2012
    Assignee: Cisco Technology, Inc.
    Inventors: Kaitki Agarwal, Rajat Ghai
  • Patent number: 8299254
    Abstract: A process for making 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, and therapeutically acceptable salts thereof, and intermediates used in the process are disclosed.
    Type: Grant
    Filed: August 18, 2009
    Date of Patent: October 30, 2012
    Assignee: Abbott Laboratories
    Inventors: Anthony Haight, David M. Barnes, Geoff G. Z. Zhang
  • Patent number: 8297977
    Abstract: Embodiments of the present invention provide a system and method for automatic driver evaluation of a person's driving capabilities and render an outcome of pass, fail, or pass with restrictions without the need for a trained observer to evaluate driver's performance. In one embodiment, the automatic driver evaluation system facilitates the display of a predetermined driving route designed for a predetermined demography, observe simulated driving performance of a user on the predetermined driving route, record errors made by the user while performing the simulated drive, and compare the performance errors to at least one threshold value and generate a score based on the comparison.
    Type: Grant
    Filed: October 23, 2007
    Date of Patent: October 30, 2012
    Assignee: Eastern Virginia Medical School
    Inventor: Barbara Freund
  • Patent number: 8301720
    Abstract: A system providing a reproducible package of a web service scenario having at least one web service client and at least one web service coupled to said network. A collector extracts a set of message exchanges between the web service client and the web service, and a closure builder captures a service description. A workspace repository coup stores the set of message exchanges and the service description to create the reproducible package of the web service scenario. According to one embodiment, the reproducible packages provide mechanisms to share and replay XML message-based scenarios for distributed applications.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: October 30, 2012
    Assignee: Progress Software Corporation
    Inventors: Anand Thakker, Aaron White, Franklin C. Grossman, James Murphy, Mark Ericson
  • Patent number: 8296819
    Abstract: Controlling identity disclosures is disclosed. A difference between a site policy as received at a first time and the site policy as received at a second time is detected through at least partially automated processing. The existence of the difference is indicated before disclosing to a relying party associated with the site policy, at or subsequent to the second time, an identity information.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: October 23, 2012
    Assignee: Symantec Corporation
    Inventors: Sourabh Satish, Brian Hernacki
  • Patent number: 8296162
    Abstract: Certain exemplary embodiments can comprise a method that can comprise, for a predetermined user, automatically determining a score for each resource from a plurality of predetermined resources based on the user's weighting of predetermined factors associated with the resources and an objective score for each factor for each resource, ranking the scored resources, and/or providing an identity of a best matched resource for the user.
    Type: Grant
    Filed: February 1, 2006
    Date of Patent: October 23, 2012
    Assignee: WebMD LLC.
    Inventors: Alan Horn, Ann Mond Johnson, Joe Donlan, Tracy Heilman, John Fiacco
  • Patent number: 8293108
    Abstract: A method for producing biofuels is provided. A method of making biofuels includes dewatering substantially intact algal cells to make an algal biomass, extracting neutral lipids from the algal biomass, and esterifying the neutral lipids with a catalyst in the presence of an alcohol. The method also includes separating a water soluble fraction comprising glycerin from a water insoluble fraction comprising fuel esters and distilling the fuel esters under vacuum to obtain a C16 or shorter fuel esters fraction, a C16 or longer fuel ester fraction, and a residue comprising carotenoids and omega-3 fatty acids. The method further includes hydrogenating and deoxygenating at least one of (i) the C16 or shorter fuel esters to obtain a jet fuel blend stock and (ii) the C16 or longer fuel esters to obtain a diesel blend stock.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: October 23, 2012
    Assignee: Heliae Developmet, LLC
    Inventor: Aniket Kale
  • Patent number: 8296255
    Abstract: A method and apparatus for automatically classifying an unknown web site to improve internet browsing control is described. In one embodiment, a method for classifying an unknown web site to control internet browsing comprising processing web site control data associated with at least one user that requested access to an unknown web site, wherein the web site control data comprises a web browsing behavior history and applying at least one metric to the web browsing behavior history to classify the unknown website.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: October 23, 2012
    Assignee: Symantec Corporation
    Inventor: Abubakar Wawda
  • Patent number: 8295078
    Abstract: An integrated circuit device (for example, logic or discrete memory device) comprising a memory cell including a punch-through mode transistor, wherein the transistor includes a source region, a drain region, a gate, a gate insulator, and a body region having a storage node which is located, at least in part, immediately beneath the gate insulator. The memory cell includes at least two data states which are representative of an amount of charge in the storage node in the body region. First circuitry is coupled to the punch-through mode transistor of the memory cell to: (1) generate first and second sets of write control signals, and (2a) apply the first set of write control signals to the transistor to write a first data state in the memory cell and (2b) apply the second set of write control signals to the transistor to write a second data state in the memory cell.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: October 23, 2012
    Assignee: Micron Technology, Inc.
    Inventors: Serguei Okhonin, Mikhail Nagoga
  • Patent number: 8296294
    Abstract: A user-interface system and method for searching among multiple documents and searching for subsections within individual documents using a single search interface on an input-constrained user device having a screen and a keypad.
    Type: Grant
    Filed: May 23, 2008
    Date of Patent: October 23, 2012
    Assignee: Veveo, Inc.
    Inventors: Rakesh Barve, Sashikumar Venkataraman
  • Patent number: 8287625
    Abstract: Embodiments of the present invention are directed to systems and methods for treating landfill gas using landfill leachate. In one embodiment of the present invention, a method includes receiving landfill leachate from at least one of a plurality of sources, and pretreating the landfill leachate to adjust at least one chemical property of at least one component of the landfill leachate. The leachate contacts landfill gas, so that at least one component of the landfill gas chemically reacts with at least one component of the landfill leachate to form a spent landfill leachate and a treated landfill gas. The method also includes recycling a first portion of the spent landfill leachate, recirculating a second portion of the spent landfill leachate to at least one of the plurality of sources, and subjecting the treated landfill gas to flare.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: October 16, 2012
    Assignee: Casella Waste Systems, Inc.
    Inventor: Douglas R. Casella
  • Patent number: 8282811
    Abstract: Disclosed are methods and systems for generating hydrogen gas at pressures high enough to fill a hydrogen storage cylinder for stationary and transportation applications. The hydrogen output of an electrochemical hydrogen gas generating device, a hydrogen-producing reactor, or a diluted hydrogen stream is integrated with an electrochemical hydrogen compressor operating in a high-differential-pressure mode. The compressor brings the hydrogen produced by the hydrogen generating device to the high pressure required to fill the storage cylinder.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: October 9, 2012
    Assignee: Giner Electrochemical Systems, LLC
    Inventors: John A. Kosek, José Giner, Anthony B. LaConti
  • Patent number: 8282905
    Abstract: The fullerenic structures include fullerenes having molecular weights less than that of C60 with the exception of C36 and fullerenes having molecular weights greater than C60. Examples include fullerenes C50, C58, C130, and C176. Fullerenic structure chemically bonded to a carbon surface is also disclosed along with a method for tethering fullerenes to a carbon material. The method includes adding functionalized fullerene to a liquid suspension containing carbon material, drying the suspension to produce a powder, and heat treating the powder.
    Type: Grant
    Filed: October 19, 2009
    Date of Patent: October 9, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Anish Goel, Jack B. Howard, John B. Vander Sande