Patents Represented by Law Firm Woodcock, Washburn, Kurtz, Mackiewics & Norris
  • Inducing resistance to tumor growth with soluble IGF-1 receptor
    Patent number: 6084085
    Abstract: Individuals having tumors are treated with pharmaceutical compositions comprising expression vectors, preferably adenovirus or retroviruses, comprising nucleic acid molecules encoding soluble IGF-1R. Such vectors express soluble IGF-1R in tumor cells resulting in reversal of the transformed phenotype, induction of apoptosis, and inhibition of tumorigenesis.
    Type: Grant
    Filed: November 13, 1996
    Date of Patent: July 4, 2000
    Assignee: Thomas Jefferson University
    Inventors: Renato Baserga, Mariana Resnicoff, Consuelo D'Ambrosio, Andre Ferber
  • Vitrifiable adhesive process
    Patent number: 4422891
    Abstract: Processes are provided for the adhering together of articles employing vitrifiable adhesives. According to a preferred embodiment, two or more articles are contacted with a polymerizable adhesive comprising a particulate, inorganic filler and a polymerizable resin comprising at least 0.25% by weight of the adhesive of a polymerizable silane. The adhesive is then polymerized and the polymerized adhesive heated to afford a vitrified bond.
    Type: Grant
    Filed: June 16, 1981
    Date of Patent: December 27, 1983
    Assignee: Dentsply Research & Development Corporation
    Inventor: Donald I. Gonser