Patents Assigned to Acelrx Pharmaceuticals, Inc.
  • Patent number: 8945592
    Abstract: Compositions and methods effective to minimize or eliminate the presence of oxidative degradation products in solid dosage forms comprising sufentanil are provided.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: February 3, 2015
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Shamim Pushpala, Larry Hamel, Stelios Tzannis, Evangeline Cruz
  • Patent number: 8905964
    Abstract: Drug storage and dispensing devices for dispensing a drug dosage form to a patient are disclosed. A cartridge includes a cartridge housing and a pusher. The cartridge housing defines a channel within which multiple tablets are disposed. The cartridge housing is configured to be removably coupled to a tablet dispensing device. A first portion of the pusher is disposed outside of the channel. A second portion of the pusher is movably disposed within the channel, and is configured to exert a force on the plurality of tablets to convey a first tablet from the channel into the tablet delivery device when the force is exerted on the first portion of the pusher.
    Type: Grant
    Filed: January 18, 2013
    Date of Patent: December 9, 2014
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Andrew I. Poutiatine, Charles Rampersaud, Thomas Schreck, William Kolosi, Sascha Retailleau
  • Publication number: 20140350054
    Abstract: Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
    Type: Application
    Filed: June 5, 2014
    Publication date: November 27, 2014
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Lawrence Hamel, Andrew I. Poutiatine
  • Patent number: 8865743
    Abstract: Compositions, systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject for treatment of pain using a device are disclosed.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: October 21, 2014
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards
  • Patent number: 8865211
    Abstract: Bioadhesive drug formulations that adhere to an oral mucosal membrane of a subject are provided together with single dose applicators and devices for delivering the drug formulations to the oral mucosa, and methods for using the same.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: October 21, 2014
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Stelios Tzannis, Larry Hamel, Pamela Palmer, Thomas Schreck, Andrew I. Poutiatine
  • Patent number: 8778394
    Abstract: Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: July 15, 2014
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine
  • Patent number: 8778393
    Abstract: Compositions, methods and systems for administration of small volume sufentanil-containing drug dosage forms to the oral mucosa of a subject are disclosed.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: July 15, 2014
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards
  • Patent number: 8753308
    Abstract: Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: June 17, 2014
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Andrew Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Thomas Schreck, Stelios Tzannis, Lawrence Hamel, William Kolosi, Sascha Retailleau
  • Publication number: 20140031975
    Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.
    Type: Application
    Filed: September 30, 2013
    Publication date: January 30, 2014
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventors: Andrew Poutiatine, Bruce Edwards, Charles Rampersaud, Pamela Palmer, Bradley Blackwood, Benjamin K. Yaffe
  • Patent number: 8574189
    Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: November 5, 2013
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Andrew Poutiatine, Bruce Edwards, Charles Rampersaud, Pamela Palmer, Bradley Blackwood, Benjamin K. Yaffe
  • Patent number: 8548623
    Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: October 1, 2013
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Andrew Poutiatine, Bruce Edwards, Charles Rampersaud, Pamela Palmer, Bradley Blackwood, Benjamin K. Yaffe
  • Patent number: 8535714
    Abstract: Compositions, systems and methods for administration of small volume sufentanil drug dosage forms via the oral transmucosal route of a subject for treatment of pain.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: September 17, 2013
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Thomas Schreck, Lawrence Hamel, Stelio Tzannis, Andrew Poutiatine
  • Patent number: 8499966
    Abstract: A method of administering small, bioadhesive drug tablets includes moving an end portion of a delivery member. A surface of the delivery member can be positioned to prevent movement of the drug tablet from a tablet cartridge channel to a delivery passage of a delivery device when the end portion of the delivery member is in a first stopped position. The end portion of the delivery member can be moved to a second position within the delivery passage such that the tablet cartridge channel is in communication with the delivery passage. The drug tablet can be conveyed into the delivery passage via the tablet cartridge channel. The end portion of the delivery member can be moved to a third position within the delivery passage to convey the drug tablet through an exit opening of the delivery device.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: August 6, 2013
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Pamela Palmer, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards, Edmond Chiu, Thomas Schreck, Stelios Tzannis, Larry Hamel
  • Publication number: 20130165481
    Abstract: Small-volume oral transmucosal dosage forms or NanoTabs® comprising a predetermined amount of a pharmaceutically active drug are provided. Exemplary applications include use of the NanoTabs® to administer a drug for the treatment of acute, post-operative or breakthrough pain.
    Type: Application
    Filed: July 30, 2012
    Publication date: June 27, 2013
    Applicant: ACELRX PHARMACEUTICALS, INC
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine
  • Publication number: 20130156842
    Abstract: Bioadhesive drug formulations that adhere to an oral mucosal membrane of a subject are provided together with single dose applicators and devices for delivering the drug formulations to the oral mucosa, and methods for using the same.
    Type: Application
    Filed: August 27, 2012
    Publication date: June 20, 2013
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventors: Stelios Tzannis, Larry Hamel, Pamela Palmer, Thomas Schreck, Andrew I. Poutiatine
  • Publication number: 20130158074
    Abstract: Compositions, methods and systems for administration of small volume sufentanil-containing drug dosage forms to the oral mucosa of a subject are disclosed.
    Type: Application
    Filed: July 23, 2012
    Publication date: June 20, 2013
    Applicant: ACELRX PHARMACEUTICALS, INC
    Inventors: Pamela Palmer, Thomas Schreck, Stelios Tzannis, Larry Hamel, Andrew I. Poutiatine, Charles Rampersaud, Bruce Edwards
  • Publication number: 20130131586
    Abstract: Drug storage and dispensing devices for dispensing a drug dosage form to a patient are disclosed. The dispensing device has a programmable lock-out feature for locking the dispensing device and is capable of detecting the identity of a user. The invention further provides a method for the treatment of subject, by administering to the subject a drug dosage form using a dispensing device of the invention.
    Type: Application
    Filed: January 18, 2013
    Publication date: May 23, 2013
    Applicant: AcelRx Pharmaceuticals, Inc.
    Inventor: AcelRx Pharmaceuticals, Inc.
  • Publication number: 20130090594
    Abstract: Systems and methods for administration of small volume sufentanil drug dosage forms to the sublingual mucosa of a subject using a device are disclosed. The dispensing device includes a lock-out feature and a means to retard or prevent saliva and/or moisture ingress such that the drug dosage forms in the device remain dry prior to administration.
    Type: Application
    Filed: November 15, 2012
    Publication date: April 11, 2013
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventor: AceIRx Pharmaceuticals, Inc.
  • Patent number: 8357114
    Abstract: Drug storage and dispensing devices for dispensing a drug dosage form are disclosed. Devices having a housing defining a nonlinear passageway and a flexible push rod to move within the nonlinear passageway are disclosed. Devices having a flexible push rod coupled to a rotation actuating member at at an end portion thereof are also disclosed.
    Type: Grant
    Filed: January 5, 2007
    Date of Patent: January 22, 2013
    Assignee: AcelRx Pharmaceuticals, Inc.
    Inventors: Andrew I. Poutiatine, Charles Rampersaud, Thomas Schreck, William Kolosi, Sascha Retailleau
  • Publication number: 20120232473
    Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.
    Type: Application
    Filed: March 9, 2012
    Publication date: September 13, 2012
    Applicant: ACELRX PHARMACEUTICALS, INC.
    Inventors: Andrew Poutiatine, Bruce Edwards, Charles Rampersaud