Abstract: Provided is an electronic device including a lower material film, an upper material film on the lower material film, a two-dimensional electron gas between the lower material film and the upper material film, a source electrode on the upper material film, a drain electrode on the upper material film, and a gate electrode on the upper material film, wherein the upper material film includes a first portion in contact with the source electrode, a second portion in contact with the gate electrode, and a third portion in contact with the drain electrode, wherein a thickness of the second portion of the upper material film is greater than a thickness of the first portion of the upper material film and a thickness of the third portion of the upper material film, wherein the voltage drop and the threshold voltage are adjusted by adjusting the thicknesses of the first to third portions of the upper material film.

Abstract: An apparatus and a method for optimizing a satellite system considering a hard error stability and a soft error stability are disclosed. The satellite system optimizing method which considers a hard error stability and a soft error stability according to an exemplary embodiment of the present disclosure includes acquiring hardware information of a processor which is loaded in the satellite system; acquiring workload information including a task which is performed by the processor; establishing a scheduling policy for the task based on the hardware information and the workload information; and quantifying a soft error stability and a hard error stability in accordance with the scheduling policy.

Abstract: Disclosed are a method and apparatus for generating a decoding position control signal for decoding using polar codes. The method and apparatus for generating a decoding position control signal for decoding using polar codes according to an embodiment of the present disclosure include generating a decoding tree obtained by forming a plurality of nodes in a hierarchical structure for a polar-encoded codeword, decoding the codeword using a successive cancellation (SC) decoding technique, and generating control signal through a preset operation relationship based on a position of a bit returned during re-decoding among the decoded codeword.

Abstract: The present invention relates to: a composition for delivering a viral antigen-derived CD8+ T cell antigen epitope or a peptide comprising same to the cytoplasm of a target cell to thereby present the epitope or peptide to major histocompatibility complex class I (MHC-1), which is an antigen-presenting molecule on the cell surface; a composition comprising same; and a use thereof.

Abstract: An apparatus for diagnosing an abnormality of a vehicle sensor is provided. The apparatus includes a sensor configured to measure an acceleration and an angular velocity of a vehicle, a camera configured to generate a front time series image frame of the vehicle, and a controller configured to estimate the acceleration and the angular velocity of the vehicle by using the front time series image frame generated by the camera and diagnose an abnormality in the sensor based on the acceleration and the angular velocity of the vehicle estimated by the controller.

Abstract: A projection optical system includes a base, a mirror on the base, and a pair of first actuators provided between the base and the mirror, and facing each other. Each of the pair of first actuators includes a first electroactive polymer film having a size that varies according to an applied voltage, and a slope of the mirror is adjusted according to a change in the size of the first electroactive polymer film.

Abstract: The present invention relates to a composition for atopy or psoriasis treatment comprising a plasma-treated liquid material. More particularly, the present invention relates to a method for producing a plasma-treated liquid material for preventing or treating atopic dermatitis or psoriasis, a pharmaceutical composition for preventing or treating a topic dermatitis or psoriasis using a plasma-treated liquid material produced according to the method, and a method for preventing or treating atopic dermatitis or psoriasis using the plasma-treated liquid material.

Abstract: The present disclosure relates to a composition for treating or diagnosing osteoarthritis targeting activin A receptor type 2B (ACVR2B). More specifically, the present disclosure provides ACVR2B as a biomarker for diagnosing osteoarthritis because it was found that expression and activity of ACVR2B were increased at an early stage of osteoarthritis, expression of Mmp3, Mmp13, and Cox2 that induce destruction of cartilage was increased thereby, and expression of the genes was suppressed by inhibition of ACVR2B expression. In addition, since it was found that osteoarthritis was alleviated by suppressing the expression of ACVR2B, the present disclosure provides an ACVR2B expression or activity inhibitor as a therapeutic agent for osteoarthritis.

Abstract: The present invention provides a composition comprising fetal cartilage tissue-derived cells and a fetal cartilage tissue-derived extracellular matrix as active ingredients for regenerating a growth plate. The composition for regenerating a growth plate can inhibit bone bridge formation in a growth plate injury region without a scaffold and differentiate to a growth plate cartilage tissue to effectively fill and regenerate the injured region therewith, whereby the regenerated growth plate tissue can recover growth ability. In addition, the composition is compatible with and safe to biological tissues and is characterized by high reproducibility and homogeneity.

Abstract: The present disclosure relates to a method for filtering selectively obstacle to be an obstacle to machine learning according to a learning purpose and a system thereof. A system for filtering obstacle data in machine learning of medical images may include an obstacle data definition unit configured to receive definitions of obstacle data according to a machine learning purpose; a filter generation unit configured to generate a filter for filtering the obstacle data; and a filtering unit configured to remove obstacle data in machine learning using the generated filter.

Abstract: A TCR-like antibody or an antigen-binding fragment thereof, the antibody binding to and having specific and improved affinity to an MHC-I molecule, particularly a CMV pp65 peptide complex (CMVP495-503/HLA-A*02:01) presented by HLA-A*02 are disclosed. A nucleic acid for coding the TCR-like antibody or the antigen-binding fragment thereof; an expression vector containing the nucleic acid; a cell transformed to the expression vector; a method for producing same; a composition containing a T cell for expressing the antibody or the antigen-binding fragment thereof as a chimeric antigen receptor; uses of the composition in preventing or treating cancer or an infectious disease; uses of the composition in diagnosis; methods for preventing and/or treating cancer or infectious diseases; and methods for diagnosing are disclosed.

Abstract: An apparatus for gene amplification includes a gene amplification chip including a well configured to accept a sample that is loaded into the well; the gene amplification chip being configured to: thermally dissolve the sample in the well so that a microbe present in the sample is thermally dissolved in the well to release genes in the microbe; and amplify the released genes in the well. The apparatus for gene amplification also includes a temperature controller configured to control a thermal dissolution temperature and a gene amplification temperature of the well.

Abstract: The present invention relates to a tissue adhesion agent having improved bio-tissue adhesiveness and bonding force by utilizing an adhesion-related gene. More specifically, a cartilage tissue adhesion composition prepared from fetal cartilage tissue-derived stem cells in which VCAN, CTGF, or EXT1 is inserted and expressed in an upregulated manner was found to show a remarkably superb adhesive force, compared to that prepared from fetal cartilage tissue-derived stem cells in which none of the genes are inserted. Accordingly, the cell composition in which the expression of VCAN, CTGF, or EXT1 is upregulated can be prepared into a tissue adhesion composition having improved bio-tissue adhesiveness and bonding force and VCAN, CTGF, or EXT1 can be provided as an additive composition for a tissue adhesion agent.

Abstract: A pharmaceutical composition, dietary supplement, or food containing a Perilla frutescens fermented extract is disclosed. The composition is useful for prevention or treatment of a sleep disorder. A composition or a fiber or fragrance composition containing a Perilla frutescens fermented extract is also disclosed. A method for treating sleep disorder employing the pharmaceutical composition, dietary supplement, food, or the fiber or fragrance composition is disclosed.

Abstract: A small molecule TNF-? inhibitor is disclosed. The compound has an activity of inhibiting the formation of a TNF-? homotrimer by specifically binding to the binding cavity of a TNF-? homodimer. A composition containing the compound as well as uses of the compound and the composition in preventing or treating autoimmune diseases and/or inflammatory diseases are disclosed. Extracellular inactivation of TNF-? through protein-protein interface destruction is the most innovative and effective method for alleviating chronic systemic inflammatory states, and TIM series compounds, which have better efficacy and lower toxicity than those of existing TNF inhibitors and have oral bioavailability, can be effectively used as leading anti-inflammatory molecules.

Abstract: Provided is a method and apparatus for selecting an airborne position reference node. A weight center coordinate of the repeaters is calculated by using position coordinates of repeaters, a plane having a vector connecting the weight center coordinate and a position coordinate of a user as a normal vector is determined, and the position coordinates of the repeaters are orthographically projected onto the plane. A certain number of repeaters located farthest from the weight center coordinate of the repeaters are selected to be airborne position reference nodes, on the basis of the orthographically projected coordinates of the repeaters and the weight center coordinate.

Abstract: The present invention relates to an injectable hydrogel composition having the recruitment of endogenous progenitors or stem cells and the induction of vascular differentiation of recruited cells, and more specifically to an injectable hydrogel composition having the recruitment of endogenous progenitors or stem cells and the induction of vascular differentiation of recruited cells, which consists of: a first solution including anionic hyaluronic acid into which a vascular differentiation inducing factor is introduced; and a second solution including a cationic material, wherein a stem cell recruitment factor is further included in the first solution and/or the second solution, and wherein a hydrogel is formed by electrostatic interaction.

Abstract: A composition for preventing or treating hearing loss, containing a Vitis vinifera leaf extract as an active ingredient, is disclosed. A pharmaceutical composition for preventing or treating hearing loss, containing the extract (a Vitis vinifera leaf extract) as an active ingredient, protects auditory hair cells in the cochlea and spiral ganglion cells from damage caused by noise and the like and effectively reduces the hearing threshold measured in the auditory nerves, thereby being usable as an agent for preventing or treating hearing loss.

Abstract: The present invention relates to a composition, comprising COTL1 as an active ingredient, for diagnosis of a bone disease or obesity. Downregulation of the expression of the COTL1 protein or a gene thereof inhibits the differentiation activity of osteoclasts to reinforce bone density, compared to a normal control, and to increase factors that induce articular inflammation and cartilage degeneration, causing a bone disease such as osteosclerosis or osteoarthritis. Thus, COTL1 protein or a gene coding therefor can be used for diagnosing, preventing, or treating a bone disease such as osteosclerosis or osteoarthritis. In addition, downregulation of the expression of COTL1 protein or a gene coding therefor exhibits an excellent effect of treating obesity by reducing body weight and body fat mass in high-fat diet obesity mouse models and suppressing hepatic fat accumulation and adipocyte sizes and can be used for diagnosing obesity.

Abstract: Disclosed is a resistive switching element. The resistive switching element includes a first oxide layer and a second oxide layer stacked one on top of the other such that an interface is present therebetween, wherein the first oxide layer and the second oxide layer are made of different metal oxides; two-dimensional electron gas (2DEG) present in the interface between the first oxide layer and the second oxide layer and functioning as an inactive electrode; and an active electrode disposed on the second oxide layer, wherein when a positive bias is applied to the active electrode, an electric field is generated between the active electrode and the two-dimensional electron gas, such that the second oxide layer is subjected to the electric field, and active metal ions from the active electrode are injected into the second oxide layer. The resistive switching element realizes highly uniform resistive switching operation.