Patents Assigned to Alcide Corporation
  • Patent number: 5597561
    Abstract: Disinfecting compositions directed to the prevention of microbial infections are disclosed. The disinfecting compositions comprise a protic acid, a metal chlorite and a gelling agent which, when combined, provide an effective adherent matrix that acts as a disinfectant barrier for preventing transmission and propagation of microbial infections. The gelling agent includes at least 25% polyacrylamide. The compositions of this invention may be used as presurgical disinfectants or as antiseptics for wounds and injection, phlebotomy and catheter insertion sites.
    Type: Grant
    Filed: December 14, 1994
    Date of Patent: January 28, 1997
    Assignee: Alcide Corporation
    Inventor: Robert D. Kross
  • Patent number: 5384134
    Abstract: There is disclosed a method for treating dermatologic diseases caused by microbial overgrowth or inflammation, such as psoriasis, fungal infections, eczema, dandruff, acne, genital herpes lesions, and leg ulcers. There is further disclosed an antiviral lubricating composition that is effective in preventing the transmission of the HIV virus and other sexually transmitted diseases. There is also disclosed systemic anti-inflammatory compositions and formulations and a method for reducing tissue inflammation in tissues such as the bowel, muscle, bone, tendon and joints (e.g., arthritis).
    Type: Grant
    Filed: September 1, 1993
    Date of Patent: January 24, 1995
    Assignee: Alcide Corporation
    Inventors: Robert D. Kross, Elliott J. Siff
  • Patent number: 5252343
    Abstract: There is disclosed methods and compositions for preventing and treating bacterial infections, including mastitis, in the udder of a mammal. The compositions include chlorine dioxide in an amount ranging from 5 ppm to 1000 ppm, and have a chlorine dioxide to chlorite ratio of at least 5:1. Methods of the present invention include the infusion of the composition into the mammal's udder, and the formation of the compositions immediately prior to infusion.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: October 12, 1993
    Assignee: Alcide Corporation
    Inventor: Robert D. Kross
  • Patent number: 5185161
    Abstract: There is disclosed, in one aspect, chlorous acid generating compositions useful for disinfecting substrates. The compositions comprise aqueous solutions containing a suitable amount of a protic acid, such as citric or malic acid, and a suitable amount of a metal chlorite, such as sodium chlorite. The chlorite ion concentration which is in the form of chlorous acid in the composition is no more than about 15 percent by weight of the total amount of chlorite ion concentration. In a preferred embodiment, the composition also contains a vicinal dihydroxy or polyhydroxy compound. In another preferred embodiment, the composition contains at least a 10-fold molar excess of a water soluble chloride ion compared to the total concentration of chlorite ion. In another aspect, there is disclosed a process for disinfecting substrates. This process comprises applying the compositions described above to a substrate. In yet another aspect, there is disclosed a process for preparing the compositions described above.
    Type: Grant
    Filed: November 27, 1990
    Date of Patent: February 9, 1993
    Assignee: Alcide Corporation
    Inventors: Eugene A. Davidson, Robert D. Kross
  • Patent number: 5100652
    Abstract: The present invention provides low concentration chlorous-acid generating compositions useful for oral hygiene. The compositions are effective oral disinfectants which do not have the strong unpleasant taste of chlorine and are useful in reducing plaque. The invention also concerns processes for making the inventive compositions and methods for using the same.
    Type: Grant
    Filed: February 28, 1990
    Date of Patent: March 31, 1992
    Assignee: Alcide Corporation
    Inventors: Robert D. Kross, Robert Lofaro, Carol A. Zamojcin
  • Patent number: 5019402
    Abstract: There is disclosed a composition and process for disinfecting or essentially sterilizing blood fractions and components of blood. The composition is formed by adding a chlorine dioxide liberating compound with a weak organic acid and a heat activated saccharide.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: May 28, 1991
    Assignee: Alcide Corporation
    Inventors: Robert D. Kross, David I. Scheer
  • Patent number: 4986990
    Abstract: There is disclosed, in one aspect, chlorous acid generating compositions useful for disinfecting substrates. The compositions comprise aqueous solutions containing a suitable amount of a protic acid, such as citric or malic acid, and a suitable amount of a metal chlorite, such as sodium chlorite. The chlorite ion concentration which is in the form of chlorous acid in the composition is no more than about 15 percent by weight of the total amount of chlorite ion concentration. In a preferred embodiment, the composition also contains a vicinal dihydroxy or polyhydroxy compound. In another preferred embodiment, the composition contains at least a 10-fold molar excess of a water soluble chloride ion compared to the total concentration of chlorite ion. In another aspect, there is disclosed a process for disinfecting substrates. This process comprises applying the compositions described above to a substrate. In yet another aspect, there is disclosed a process for preparing the compositions described above.
    Type: Grant
    Filed: October 11, 1989
    Date of Patent: January 22, 1991
    Assignee: Alcide Corporation
    Inventors: Eugene A. Davidson, Robert D. Kross
  • Patent number: 4956184
    Abstract: There is disclosed a method for treating dermatologic diseases caused by microbial overgrowth or inflammation, such as psoriasis, fungal infections, eczema, dandruff, acne, genital herpes lesions, and leg ulcers. There is further disclosed an antiviral lubricating composition that is effective in preventing the transmission of the HIV virus and other sexually transmitted diseases. There is also disclosed systemic anti-inflammatory compositions and formulations and a method for reducing tissue inflammation in tissues such as the bowel, muscle, bone, tendon and joints (e.g. arthritis).
    Type: Grant
    Filed: June 3, 1988
    Date of Patent: September 11, 1990
    Assignee: Alcide Corporation
    Inventor: Robert D. Kross
  • Patent number: 4891216
    Abstract: There is disclosed, in one aspect, a composition for forming a protective barrier while disinfecting substrates such as human or animal skin. The composition comprises two gels adapted to be simultaneously applied and mixed in situ and to adhere onto the substrate. The first gel comprises an aqueous solution containing suitable amounts of a protic acid, preferably lactic acid. The second gel comprises an amount of a metal chlorite such as sodium chlorite, such that the chlorite ion concentration in the form of chlorous acid in the combined gels is no more than about 15% by weight of the total amount of chlorite ion concentration. The second gel also contains a polysulfonic acid salt. The anion of that salt has the formula: ##STR1## wherein X has a value such that the molecular weight of the anionic portion of the polymer is from about 1,000,000 to about 5,000,000. In another aspect, there is disclosed a method for treating skin diseases.
    Type: Grant
    Filed: April 14, 1987
    Date of Patent: January 2, 1990
    Assignee: Alcide Corporation
    Inventors: Robert D. Kross, Carol A. Zamojcin
  • Patent number: RE31779
    Abstract: Germ-killing composition produced by contacting an acid material, preferably consisting of at least about 15% by weight of lactic acid, with sodium chlorite in aqueous media, the amount of acid being sufficient to lower the .[.PH.]. .Iadd.pH .Iaddend.of the aqueous media to less than about 7. Methods of disinfecting and sanitizing include application of either the germ killing composition, or reactants providing in situ production thereof, to a germ carrier including substrates of various kinds as well as an enclosed air space.
    Type: Grant
    Filed: April 17, 1980
    Date of Patent: December 25, 1984
    Assignee: Alcide Corporation
    Inventor: Howard Alliger