Patents Assigned to Alere Switzerland GmbH
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Patent number: 8980177Abstract: Disclosed is a fluidic assay device for assaying at least one property of a liquid sample, the device comprising: (i) a liquid sample application region; (ii) at least one test flow path in liquid flow communication with the sample application region; (iii) a reference flow path in liquid flow communication with the sample application region; and (iv) a junction region, at which the test flow path and the reference flow path contact one another, the junction region typically comprising an outlet, conduit, chamber or other portion which permits the onward flow of liquid; wherein a liquid flowing along the reference flow path, upon reaching the junction region, has the effect of preventing the flow of liquid along the test flow path. The invention relates to a fluidic device for the passage of a liquid. It also relates to an assay device suitable for measurement of the amount and/or presence of an analyte in, or property of, a fluid sample.Type: GrantFiled: July 2, 2013Date of Patent: March 17, 2015Assignee: Alere Switzerland GmbHInventors: Stephen John Carlisle, David Tolley
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Publication number: 20150031053Abstract: The present invention provides for a home test or a point of care test device that can both detect blood glucose and insulin levels and methods using said device. The device and methods can be used to aid diabetic patients and medical practitioners to fine tune insulin administration, and to monitor disease progression or treatment.Type: ApplicationFiled: February 10, 2012Publication date: January 29, 2015Applicant: ALERE SWITZERLAND GMBHInventor: Piet Moerman
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Patent number: 8871155Abstract: A device for detecting the presence or amount of an analyte in a fluid sample and method thereof, comprises a sample collector and a receiving cup for receiving and holding the sample collector within the receiving cup. The sample collector contains a compressible absorbent member for collecting the fluid sample, and has a first position and a second, locked position within the receiving cup. The absorbent member is uncompressed in the first position and is compressed in the second, locked position. The sample collector or the receiving cup has at least one test element having reagents for detecting the presence or amount of the analyte in the fluid sample.Type: GrantFiled: November 13, 2006Date of Patent: October 28, 2014Assignee: Alere Switzerland GmbHInventors: Yuzhang Wu, Yun Ling, Jielin Dai
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Patent number: 8865458Abstract: The present invention includes but is not limited to a specimen collection device that includes a chamber capable of collecting a specimen, a specimen passage slot, a reservoir, a reservoir seal, and a test device. A sample or specimen added to the chamber flows through the specimen passage slot into the reservoir. Flow into the reservoir may be limited by the reservoir seal. The test device positioned within the reservoir detects the presence or concentration of an analyte within the sample or specimen.Type: GrantFiled: February 25, 2013Date of Patent: October 21, 2014Assignee: Alere Switzerland GmbHInventors: James T. Ramsey, Larry Hartselle
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Patent number: 8865088Abstract: Disclosed is an assay device for use in the determination of the presence of at least one analyte of interest in a liquid sample; the device comprising a reaction zone in which a reagent reacts with the analyte of interest and a bibulous member which, when contacted with the liquid sample, draws liquid therefrom towards the reaction zone; the bibulous member comprising means to change color when wetted by the sample.Type: GrantFiled: January 9, 2003Date of Patent: October 21, 2014Assignee: Alere Switzerland GmbHInventors: Barry Sinclair Brewster, Susan Catrin Day, Peter John Skelly, Jill Crawford
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Patent number: 8828739Abstract: Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.Type: GrantFiled: May 25, 2012Date of Patent: September 9, 2014Assignee: Alere Switzerland GmbHInventors: Huiyan Guo, Min Wang, Tao Shang, Hui-Kang Chen, Fei Gao
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Patent number: 8721990Abstract: Disclosed is an assay device for the determination of the presence and/or extent if an analyte in a liquid sample over an extended concentration range comprising a first assay and a second assay, wherein the first assay for an analyte comprises a first flow-path having a sole detection zone capable of immobilizing a labelled binding reagent and the second assay for said analyte comprises a second flow-path having a sole detection zone capable of immobilizing a labelled binding reagent, wherein the presence of labelled binding reagent at the detection zones provides an indication of the presence and/or extent of analyte in said liquid sample.Type: GrantFiled: April 9, 2008Date of Patent: May 13, 2014Assignee: Alere Switzerland GmbHInventors: Balbir Raj, Saji Eapen, Ezra Linley
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Publication number: 20140093427Abstract: Disclosed is an assay device comprising liquid transport means adapted to take up a liquid sample and conduct the liquid to an analyte detection region operable to provide a test signal indicative of the presence and/or amount of an analyte in the liquid sample; the assay device further comprising a sample presence signal generation means, which is not generated by means of immunoreaction. This sample presence signal generation means can comprise a coloured portion, which is overlaid by a material (e.g. nitrocellulose) that is opaque, when dry, and translucent or transparent, when wet, to allow the coloured portion to become visible to the user. In another embodiment the signal generation means comprises a colour changing material which under-goes a change in its visible properties upon wetting (eg. pH indication). A third embodiment uses a mobilisable detectable which, when wetted by the sample, is carried along resulting in a streaked line parallel with the flow direction.Type: ApplicationFiled: May 17, 2013Publication date: April 3, 2014Applicant: Alere Switzerland GmbHInventors: Barry Sinclair Brewster, Adrian Leslie Walker, Robert John Davies
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Patent number: 8617907Abstract: A method for determining the presence or amount of a metal-labelled species in a sample may include causing the metal of the metal-labelled species in the sample to form a soluble electrochemically-active complex which is stable relative to moieties present or potentially present in the sample which will form an insoluble and/or electrochemically-inactive complex with the metal, and electrochemically measuring the formed complex to provide an indication of the presence or amount of the metal-labelled species.Type: GrantFiled: June 7, 2005Date of Patent: December 31, 2013Assignee: Alere Switzerland GmbHInventors: Brian Jeffrey Birch, Camilla Sofia Forssten, Alena Kabil, Robert Andrew Porter
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Publication number: 20130287650Abstract: The present invention includes but is not limited to a specimen collection device that includes a chamber capable of collecting a specimen, a specimen passage slot, a reservoir, a reservoir seal, and a test device. A sample or specimen added to the chamber flows through the specimen passage slot into the reservoir. Flow into the reservoir may be limited by the reservoir seal. The test device positioned within the reservoir detects the presence or concentration of an analyte within the sample or specimen.Type: ApplicationFiled: February 25, 2013Publication date: October 31, 2013Applicant: ALERE SWITZERLAND GMBHInventor: Alere Switzerland GmbH
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Patent number: 8492136Abstract: Disclosed is a fluidic assay device for assaying at least one property of a liquid sample comprising: a liquid sample application region; at least one test flow path in liquid flow communication with the sample application region; a reference flow path in liquid flow communication with the sample application region; and a junction region, at which the test flow path and the reference flow path contact one another, the junction region typically comprising an outlet, conduit, chamber or other portion which permits the onward flow of liquid; wherein a liquid flowing along the reference flow path, upon reaching the junction region, has the effect of preventing the flow of liquid along the test flow path. The invention relates to a fluidic device for the passage of a liquid and an assay device suitable for measurement of the amount and/or presence of an analyte in, or property of, a fluid sample.Type: GrantFiled: September 27, 2011Date of Patent: July 23, 2013Assignee: Alere Switzerland GmbHInventors: Stephen John Carlisle, David Tolley
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Publication number: 20130183681Abstract: A device for remote management of patients suffering or likely to suffer from heart failure that can measure the amplitude and frequency changes of one or more biomarkers. The device aids in predicting the need for medical intervention in such patients. The device may further aid in monitoring the efficacy and safety of treatment in such patients.Type: ApplicationFiled: March 7, 2013Publication date: July 18, 2013Applicant: ALERE SWITZERLAND GMBHInventor: ALERE SWITZERLAND GMBH
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Patent number: 8486353Abstract: Medical and environmental diagnostic devices are described and claimed. Preferred embodiments feature cup (1) within cup configurations wherein one cup is dedicated, for the most part, to sample collection and another cup (2) is dedicated, for the most part, to assay performance. Communication between the cups is afforded by what is believed to be a unique valve assembly (3) and lid (7) tandem.Type: GrantFiled: August 27, 2007Date of Patent: July 16, 2013Assignee: Alere Switzerland GmbHInventors: Yuzhang Wu, Lijiang Guo, Jeilin Dai, Hsiaoho Tung
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Publication number: 20130149776Abstract: A device for determining an assay result may include a test strip, a light source system, a light detection system, and a processor.Type: ApplicationFiled: June 29, 2012Publication date: June 13, 2013Applicant: Alere Switzerland GmbHInventors: Stephen P. Sharrock, Andrew P. Phelan
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Patent number: 8454903Abstract: Disclosed is an assay device comprising liquid transport means adapted to take up a liquid sample and conduct the liquid to an analyte detection region operable to provide a test signal indicative of the presence and/or amount of an analyte in the liquid sample; the assay device further comprising a sample presence signal generation means, which is not generated by means of an immunoreaction. This sample presence signal generation means can comprise a colored portion, which is overlaid by a material (e.g. nitrocellulose) that is opaque, when dry, and translucent or transparent, when wet, to allow the colored portion to become visible to the user. In another embodiment the signal generation means comprises a color changing material which under-goes a change in its visible properties upon wetting (eg. pH indication). A third embodiment uses a mobilisable detectable which, when wetted by the sample, is carried along resulting in a streaked line parallel with the flow direction.Type: GrantFiled: June 26, 2003Date of Patent: June 4, 2013Assignee: Alere Switzerland GmbHInventors: Barry Sinclair Brewster, Adrian Leslie Walker, Robert John Davies
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Publication number: 20130065245Abstract: Provided is an assay device and kit for detecting the presence or amount of an analyte of interest.Type: ApplicationFiled: August 29, 2012Publication date: March 14, 2013Applicant: Alere Switzerland GmbHInventors: Paul Rutter, Chris Jones, Andrew Ledgeway, James Gani, Bryan Tissington
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Patent number: 8394626Abstract: The present invention includes but is not limited to a specimen collection device that includes a chamber capable of collecting a specimen, a specimen passage slot, a reservoir, a reservoir seal, and a test device. A sample or specimen added to the chamber flows through the specimen passage slot into the reservoir. Flow into the reservoir may be limited by the reservoir seal. The test device positioned within the reservoir detects the presence or concentration of an analyte within the sample or specimen.Type: GrantFiled: June 2, 2009Date of Patent: March 12, 2013Assignee: Alere Switzerland GmbHInventors: James T. Ramsey, Larry Hartselle
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Patent number: 8377635Abstract: A method of controlling the flow of an aqueous fluid in a microfluidic device, which makes use of a fluid gate comprising a UCST (upper critical solubility temperature) polymer and which allows fluid to flow by raising the temperature of the fluid gate above the USCT. Also provided is a device incorporating such a fluid gate and the use of such a device to detect an analyte in an aqueous fluid sample.Type: GrantFiled: February 12, 2007Date of Patent: February 19, 2013Assignee: Alere Switzerland GmbHInventors: Andrew Antony Brown, Omar Azzaroni, Wilhelm T. S. Huck
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Publication number: 20130029350Abstract: In accordance with the present invention there is provided a bi-stable oscillator circuit for detecting a load imparted to a surface. The bi-stable oscillator comprises an electrical amplifier, at least one resonator comprising an electrical transducer having a resonant frequency, a surface of the resonator forming the surface on which the load is to be detected and an impedance network having a resonant frequency.Type: ApplicationFiled: January 19, 2011Publication date: January 31, 2013Applicant: Alere Switzerland GmbHInventors: Matthew Cooper, Alexander Sleptsov, Richard John Hammond
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Patent number: 8353848Abstract: A disposable test device consists of a first portion 2 having a fluid application port 5 to which a sample of fluid can be applied, and a handle portion 3 hingedly attached to the first portion 2 at a hinge portion 4 and which normally lies in the plane of the first portion. In use the device is held by the handle portion 3 and the first portion inserted into a measuring instrument. The handle is then deflected downwardly e.g. by the finger of a person to supply a drop of fluid to the port 5.Type: GrantFiled: November 21, 2006Date of Patent: January 15, 2013Assignee: Alere Switzerland GmbHInventors: Nicholas Long, Jon Johnson