Patents Assigned to Allergan Sales, LLC
  • Publication number: 20220387449
    Abstract: This disclosure relates to compositions, kits and methods for non-surgical reduction of localized subcutaneous fat such as that associated with a cosmetic fat accumulation. The methods employ compositions having specific concentrations of a salt of deoxycholic acid which provides a superior fat cell necrosis with modest adverse effects. Examples of localized subcutaneous fat are found in the submental area, in particular under the chin.
    Type: Application
    Filed: May 24, 2022
    Publication date: December 8, 2022
    Applicant: Allergan Sales, LLC
    Inventor: Patricia Walker
  • Publication number: 20220387284
    Abstract: The present invention relates to a topical composition that can be used to treat skin laxity, cellulite and to firm, smooth and/or tone skin.
    Type: Application
    Filed: May 25, 2022
    Publication date: December 8, 2022
    Applicant: ALLERGAN SALES, LLC
    Inventors: Patrick Nido, Kuniko Kadoya, Prithwiraj Maitra, Rahul Mehta, Elizabeth Makino
  • Publication number: 20220331258
    Abstract: Provided herein are poly(ether ester) multi-block copolymers (PEE-MBCP). Also provided herein are injectable delivery systems or pharmaceutical compositions, comprising a PEE-MBCP provided herein, either alone or in combination with a binding protein, such as abicipar. Also provided herein are methods of using these injectable delivery systems or pharmaceutical compositions provided herein for the treatment of ocular disorders.
    Type: Application
    Filed: September 30, 2020
    Publication date: October 20, 2022
    Applicant: Allergan Sales, LLC
    Inventors: Patrick Hughes, Hongwen Rivers, Jie Shen, Johan Zuidema, Henk Haitjema, Christine Hiemstra, Rob Steendam
  • Publication number: 20220218584
    Abstract: The present invention relates to a topical composition that can be used to treat skin aging of the neck and d├ęcolletage area.
    Type: Application
    Filed: January 13, 2022
    Publication date: July 14, 2022
    Applicant: ALLERGAN SALES, LLC
    Inventors: Patrick Nido, Kuniko Kadoya, Prithwiraj Maitra, Rahul Mehta, Elizabeth Makino
  • Patent number: 11344561
    Abstract: This disclosure relates to compositions, kits and methods for non-surgical reduction of localized subcutaneous fat such as that associated with a cosmetic fat accumulation. The methods employ compositions having specific concentrations of a salt of deoxycholic acid which provides a superior fat cell necrosis with modest adverse effects. Examples of localized subcutaneous fat are found in the submental area, in particular under the chin.
    Type: Grant
    Filed: April 27, 2017
    Date of Patent: May 31, 2022
    Assignee: Allergan Sales, LLC
    Inventor: Patricia Walker
  • Publication number: 20220117977
    Abstract: Formulations and methods for providing progestin-only contraception to a woman including transdermally administering to a woman a formulation having a contraceptively effective amount of progestin-only hormonal agents as part of a contraceptive regimen.
    Type: Application
    Filed: December 29, 2021
    Publication date: April 21, 2022
    Applicant: ALLERGAN SALES, LLC
    Inventors: Charles Ebert, Gary Hoel, Angela Anigbogu, Samir Roy
  • Publication number: 20220072011
    Abstract: Provided herein are methods of treating a variety of disorders related to fat accumulation in humans with pharmaceutical formulations containing deoxycholic acid.
    Type: Application
    Filed: April 30, 2021
    Publication date: March 10, 2022
    Applicant: Allergan Sales, LLC
    Inventors: Frederick Beddingfield, Elisabeth Sandoval, Nancy Jorgesen, Serge Lichtsteiner, Paul Lizzul, Todd Gross, Christine Somogyi
  • Patent number: 11202786
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: December 21, 2021
    Assignee: Allergan Sales, LLC
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Patent number: 11179404
    Abstract: The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: November 23, 2021
    Assignee: Allergan Sales, LLC
    Inventors: Robert Emil Hodge, Jeffrey Douglas Webster
  • Publication number: 20210252021
    Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
    Type: Application
    Filed: February 17, 2021
    Publication date: August 19, 2021
    Applicant: ALLERGAN SALES, LLC
    Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
  • Patent number: 11026955
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: June 8, 2021
    Assignee: Allergan Sales, LLC
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Patent number: 11008363
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: May 18, 2021
    Assignee: Allergan Sales, LLC
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, Jr., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Patent number: 10981946
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-?-hydroxysteroids from ?-9,11-ene, 11-keto or 11-hydroxy-?-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: April 20, 2021
    Assignee: Allergan Sales, LLC
    Inventors: Robert M. Moriarty, Achampeta Rathan Prasad, John Gregory Reid, Roy A. Swaringen, Jr.
  • Patent number: 10946030
    Abstract: The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: March 16, 2021
    Assignee: Allergan Sales, LLC
    Inventors: Robert Emil Hodge, Jeffrey Douglas Webster, Robert M. Moriarty
  • Publication number: 20200317716
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Application
    Filed: April 23, 2020
    Publication date: October 8, 2020
    Applicant: ALLERGAN SALES, LLC
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, JR., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Patent number: 10633412
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: April 28, 2020
    Assignee: Allergan Sales, LLC
    Inventors: Achampeta Rathan Prasad, Roy A. Swaringen, Jr., John Gregory Reid, Robert M. Moriarty, Akhila Kumar Sahoo
  • Publication number: 20200095274
    Abstract: Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-?-hydroxysteroids from ?-9,11-ene, 11-keto or 11-hydroxy-?-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone.
    Type: Application
    Filed: October 2, 2019
    Publication date: March 26, 2020
    Applicant: ALLERGAN SALES, LLC
    Inventors: Robert M. Moriarty, Achampeta Rathan Prasad, John Gregory Reid, Roy A. Swaringen, Jr.
  • Publication number: 20200085843
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Application
    Filed: September 25, 2019
    Publication date: March 19, 2020
    Applicant: ALLERGAN SALES, LLC
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Publication number: 20200078373
    Abstract: Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being free of all moieties of animal origin and free of pyrogenic moieties.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 12, 2020
    Applicant: ALLERGAN SALES, LLC
    Inventors: Robert M. Moriarty, Nathaniel E. David, Nadir Ahmeduddin Mahmood
  • Publication number: 20200078354
    Abstract: The invention relates to an abuse deterrent immediate release tablet.
    Type: Application
    Filed: November 15, 2019
    Publication date: March 12, 2020
    Applicant: Allergan Sales, LLC
    Inventors: Rahul Sareen, Shahin Fesharaki, Parag Shah