Patents Assigned to Amarin Pharmaceuticals Ireland Limited
  • Methods of reducing the risk of cardiovascular events in a subject
    Patent number: 11116742
    Abstract: In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
    Type: Grant
    Filed: January 20, 2021
    Date of Patent: September 14, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Paresh Soni
  • Methods of reducing the risk of cardiovascular events in a subject
    Patent number: 11116743
    Abstract: In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
    Type: Grant
    Filed: February 2, 2021
    Date of Patent: September 14, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Paresh Soni
  • Stable pharmaceutical composition and methods of using same
    Patent number: 11103477
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Grant
    Filed: September 10, 2020
    Date of Patent: August 31, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
    Patent number: 11058661
    Abstract: In various embodiments, the present disclosure provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof having triglyceride levels of about 200 mg/dL to about 499 mg/dL, and hsCRP levels ?2.0 mg/L.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: July 13, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Sephy Philip
  • Methods of reducing RLP-C
    Patent number: 11052063
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: July 6, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Pharmaceutical compositions comprising EPA and a cardiovascular agent and methods of using the same
    Patent number: 11033523
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising EPA and one or more cardiovascular agents, and to therapeutic methods for treating various diseases and disorders using the same.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: June 15, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
    Patent number: 11007173
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing a cardiovascular-related disease in subject in need thereof.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: May 18, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Jonathan Rowe
  • Methods of reducing the risk of cardiovascular events in a subject
    Patent number: 11000499
    Abstract: In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: May 11, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Paresh Soni
  • Methods of treating mixed dyslipidemia
    Patent number: 10987331
    Abstract: The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: April 27, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Compositions and methods for lowering levels of high-sensitivity C-reactive protein (hs-CRP) in a subject
    Patent number: 10973796
    Abstract: The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. In some embodiments, the method comprises lowering high sensitivity CRP (hs-CRP) levels in a subject including, for example, a subject with a HbA1c value of about 5.00%-8.50% or at least about 6.8%.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: April 13, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Methods of reducing apolipoprotein c-III
    Patent number: 10973797
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: April 13, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
  • Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
    Patent number: 10966968
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing triglycerides in a subject on rosiglitazone therapy, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: April 6, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Rene Braeckman, William Stirtan, Paresh Soni
  • Compositions and methods for lowering triglycerides in a subject having reduced kidney function
    Patent number: 10966951
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject having reduced kidney function.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: April 6, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Sephy Philip
  • Methods of treating mixed dyslipidemia
    Patent number: 10940131
    Abstract: The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: March 9, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Methods of reducing the risk of a cardiovascular event in a subject at risk for cardiovascular disease
    Patent number: 10894028
    Abstract: In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a cardiovascular event in a subject on statin therapy having a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL, and administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: January 19, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Paresh Soni
  • Pharmaceutical compositions comprising omega-3 fatty acids
    Patent number: 10888537
    Abstract: The present disclosure relates to, inter alia, pharmaceutical compositions comprising omega-3 fatty acids.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: January 12, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Jonathan Rowe
  • Methods of treating or preventing prostate cancer
    Patent number: 10888539
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing prostate cancer and, in particular, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: January 12, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Joseph S. Zakrzewski
  • Stable pharmaceutical composition and methods of using same
    Patent number: 10881632
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: January 5, 2021
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
    Patent number: 10851374
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: December 1, 2020
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Joseph S. Zakrzewski
  • Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids
    Patent number: 10842765
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing sdLDL oxidation in a subject, the method comprising administering to the subject a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: November 24, 2020
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Richard Preston Mason