Patents Assigned to America, as Represented by the Secretary of Commerce
  • Patent number: 11939345
    Abstract: A physiologically stable fluorophore includes a terminal moiety including a terminal reactive site that reacts with a reactive group of a substrate; a stability linker covalently bonded to the terminal moiety; and a bridge moiety covalently bonded to the stability linker such that the stability linker is interposed through chemical bonds between the bridge moiety and the terminal moiety; and a fluorescent moiety covalently bonded to the bridge moiety of the redox moiety and including: an electron bandgap mediator that is covalently bonded to the bridge moiety; a coordinate center covalently bonded to the electron bandgap mediator and that forms a Zwitterionic member with an atom in the electron bandgap mediator; and a steric hinder bonded to the electron bandgap mediator to provide steric hindrance for protection of the coordinate center.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: March 26, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Jeremiah Wallace Woodcock, Jeffrey William Gilman, Douglas Matthew Fox
  • Patent number: 11940714
    Abstract: A quantum EIT-based optical switch includes a first waveguide, linear or nonlinear, a separate nonlinear waveguide evanescently coupled to the first waveguide, and a pump coupled to the nonlinear waveguide. A quantum STIRAP-based optical transduction device, which includes an auxiliary, intermediate spectral state for the quantum signal that aids efficient transduction of the quantum signal from the input spectral state to the output spectral state in a single device.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: March 26, 2024
    Assignees: University of Maryland, College Park, Government of the United States of America, as Represented by the Secretary of Commerce
    Inventors: Ivan A. Burenkov, Sergey V. Polyakov
  • Patent number: 11940276
    Abstract: An inertial point-source matter-wave atom interferometer gyroscope includes an analyzer that receives fringe images of gyroscope atoms and includes: a first fringe image that includes a first fringe phase, a second fringe image that includes a second fringe phase; and a third fringe image that includes a third fringe phase, wherein the first fringe phase, the second fringe phase, and the third fringe phase are different; a phase mapper of the analyzer that produces a interferometric phase map for the gyroscope atoms from the fringe images of the gyroscope atoms; and a fitter of the analyzer in communication with the phase mapper and that receives the interferometric phase map from the analyzer and determines inertial parameters of the gyroscope atoms from the interferometric phase map, the inertial parameters including an acceleration and a rotation rate of the inertial point-source matter-wave atom interferometer gyroscope relative to the gyroscope atoms.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: March 26, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: John Edward Kitching, Elizabeth Ann Donley, Azure Lynn Hansen, Yun-Jhih Chen
  • Patent number: 11933922
    Abstract: Hybrid subtractive-additive production of a superconducting multi-layer transition-edge sensor includes: forming a superconductor layer; forming a patterning photoresist on the superconductor layer; forming a sensor pattern in the patterning photoresist; subtractively forming, from the superconductor layer, the superconductor sensor layer; removing the patterning photoresist from the superconductor sensor layer; forming a template photoresist on the superconductor sensor layer; forming an inverse normal metal layer pattern in the template photoresist and exposing a bilayer portion of the superconductor sensor layer for addition of a normal metal layer; and additively forming the normal metal layer on the superconductor sensor layer such that the sensor pattern is interposed between the normal metal layer and the substrate.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: March 19, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Daniel Richard Schmidt, Joel Calvin Weber
  • Patent number: 11905504
    Abstract: A body cube for culturing tissue that includes: an organ chip holder; and a body barrier chip and a first body organ chip disposed in the organ chip holder, the first body organ chip including a first cell culture chamber that receives cell culture medium and produces a first tissue in the first cell culture chamber, such that the organ chip holder receives cell culture medium and communicates the cell culture medium to the first cell culture chamber of the first body organ chip in response to rotation of the organ chip holder.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: February 20, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Mandy Brigitte Esch, Longyi Chen
  • Patent number: 11906350
    Abstract: A calibration apparatus for calibrating a laser Doppler vibrometer includes: a frequency shifter stage that: receives, from the laser Doppler vibrometer, primary laser light; produces frequency shifted light; communicates the frequency shifted light to a reflector; receives frequency shifted light reflected by the reflector; produces secondary light; and communicates the secondary light to the laser Doppler vibrometer, such that the laser Doppler vibrometer receives the secondary light from the frequency shifter stage and produces a synthetic velocity shift from the secondary light; and the reflector that receives and reflects the frequency shifted light back to the frequency shifter stage.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: February 20, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Michael Gaitan, Jon Clement Geist, Benjamin James Reschovsky, Akobuije Douglas Eziani Chijioke
  • Patent number: 11885979
    Abstract: High-performance optical-metasurface-based components configured to at frequencies of UV light and, in particular, in deep UV range and performing multiple optical-wavefront-shaping functions (among which there are high-numerical-aperture lensing, accelerating beam generation, and hologram projection). As a representative material for such components, hafnium oxide demands creation and establishment of a novel process of manufacture that is nevertheless based on general principles of Damascene lithography, to be compatible with existing technology and yet sufficient for producing high-aspect-ratio features that currently-used materials and processes simply do not deliver. The described invention opens a way towards low-form-factor, multifunctional ultraviolet nanophotonic platforms based on flat optical components and enabling diverse applications including lithography, imaging, spectroscopy, and quantum information processing.
    Type: Grant
    Filed: December 29, 2020
    Date of Patent: January 30, 2024
    Assignees: UNIVERSITY OF MARYLAND, COLLEGE PARK, GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Cheng Zhang, Shawn Divitt, Wenqi Zhu, Amit Kumar Agrawal, Henri Lezec
  • Patent number: 11879952
    Abstract: An atomic vapor cell for performing RF measurements includes: a first optical window of transparent nonconducting material free of electrically conductive materials; an intermediate frame of transparent nonconducting material free of electrically conductive materials; a second optical window disposed on the intermediate frame and including transparent nonconducting material free of electrically conductive materials to minimize distortion of radiofrequency fields by the windows and frame; and a cell aperture, wherein the atomic vapor cell is hermetically sealed by bonding between the first optical window and the second optical window to the intermediate frame.
    Type: Grant
    Filed: July 13, 2021
    Date of Patent: January 23, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Christopher Lee Holloway, John Edward Kitching, Alexandra Brae Artusio-Glimpse, Vladimir Anatolyevich Aksyuk, Matthew Thomas Simons, Omar Daniel Lopez
  • Patent number: 11876211
    Abstract: A prelithiated lithium ion battery includes: ion beam implanted lithium; a cathode; and an anode disposed on the cathode and an electrolyte in electrical communication with the cathode and the anode, the cathode or the anode including the ion beam implanted lithium such that: when the cathode includes the ion beam implanted lithium, the ion beam implanted lithium is present in an absence of solid electrolyte interface composition in the cathode; and when the anode includes the ion beam implanted lithium, the ion beam implanted lithium is present in an absence of solid electrolyte interface composition in the anode.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: January 16, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Vladimir Pavlovich Oleshko, Christopher Lloyd Soles, Jabez Jenkins McClelland
  • Patent number: 11874504
    Abstract: Disclosed is an optoelectromechanical switch that includes: an optical feedline disposed on an isolation substrate that receives resonator light that is subject to optical communication to a resonator when a cavity length of the resonator supports an electromagnetic mode at the wavelength of the resonator light; a resonator including: a low refractive index optical layer and receives substrate electrical counter potential; a non-conductive spacer; the electrically conductive membrane and that receives a membrane electrical potential and deflects toward and away from the electrically conductive high-index optical waveguide based on a difference in potential between the membrane electrical potential and the substrate electrical counter potential; the cavity length that is variable and under electromechanical control.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: January 16, 2024
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Vladimir Anatolyevich Aksyuk, Christian Haffner, Henri J. Lezec, Andreas Joerg, Mikael Mazur, Daniel Chelladurai, Jueg Leuthold
  • Patent number: 11860420
    Abstract: An optical cavity includes a ring defining an internal boundary and an external boundary, at least one of which is periodically modulated to define a gear-shaped configuration including a plurality of teeth, thereby enabling a plurality of slow-light modes. At least one physical defect may be defined within the periodically modulated internal boundary and/or external boundary to thereby enable at least one localized mode. At least one waveguide is coupled to the ring.
    Type: Grant
    Filed: February 17, 2022
    Date of Patent: January 2, 2024
    Assignees: University of Maryland, College Park, Government of the United States of America, as Represented by the Secretary of Commerce
    Inventors: Kartik Srinivasan, Xiyuan Lu
  • Patent number: 11844337
    Abstract: Embodiments of the present invention relate to methods and apparatus for sorting undesired marine species during trawling, provides a pliable grid when the trawl net is pulled from the water and wound tightly on the net reel, and when the trawl is deployed in the water, the apparatus is fixed into place inside the trawl and holding its shape with consistent grid spacing. Marine species sorting apparatus in accordance with embodiments of the present invention includes grid, back straps, and lead ring. Grid includes a plurality of bars surrounded by grid frame. Grid frame is attached to lead ring at an angle using terminal couplers. Lead ring supports grid and secures marine species sorting apparatus in trawl webbing referred to as the extension.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: December 19, 2023
    Assignee: UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventor: Nicholas Hopkins
  • Patent number: 11817173
    Abstract: Systems and methods are provided herein that implement and utilize temporal state machines and other temporal computational/memory circuits. For example, a temporal state machine is provided that comprises a temporal computational unit comprising at least one circuit to perform a time-domain operation, and a temporal memory unit. Both the temporal computational unit and temporal memory unit can operate using solely, or partially, time-encoded wavefronts. The computation unit accesses time-encoded wavefronts from the memory and can output and write time-encoded wavefronts back to the memory.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: November 14, 2023
    Assignees: UNIVERSITY OF MARYLAND, COLLEGE PARK, GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Advait Madhavan, Matthew William Daniels, Mark David Stiles
  • Publication number: 20230305289
    Abstract: A dynamically tunable composition, a device including the composition, a method of dynamically tuning radiation transmission through the composition, and a method of thermo-reversibly controlling operation of a filter formed from the composition. The composition includes a plurality of nanoparticles dispersed in a single phase region of a binary solvent systems composed of a first solvent and a second solvent, the nanoparticles having a preferential wettability to the first solvent. Changing temperature of the composition causes it to transition thermo-reversibly from the liquid state to a gel state having bi-continuous domains, including a particle domain and a solvent domain. The particle domain features nanoparticles dispersed in a first-solvent-rich fraction of the binary solvent system, and the solvent domain is a second-solvent-rich fraction of the binary solvent system.
    Type: Application
    Filed: July 27, 2021
    Publication date: September 28, 2023
    Applicants: University of Delaware, Government of the United States of America, as represented by the Secretary of Commerce
    Inventors: Yuyin Xi, Yun Liu
  • Patent number: 11768147
    Abstract: A quantum flow cytometer for detecting an analyte with photon-number statistics includes: a flow cytometer that: receives a pump light in a first direction; receives an analyte flow comprising the analyte in a second direction; and produces scattered light from scattering the pump light by the analyte; a single photon detector in optical communication with the flow cytometer and that: receives, in a third direction, the scattered light from the flow cytometer; provides a correlative time-of-arrival waveform comprising photon-number statistics as an amplitude and an integrated area, the integrated area being proportional to a number of photons received by the single photon detector, wherein the first direction, the second direction, and the third direction are arranged at oblique angles.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: September 26, 2023
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Sergey Vladimirovich Polyakov, Ivan Alexandrovich Burenkov, Yu-Hsiang Cheng
  • Patent number: 11761888
    Abstract: An infrared thermal desorber includes a desorption housing; an infrared source receiver that receives an infrared emission source; an infrared absorber receiver that receives an infrared absorber, such that the infrared absorber receiver produces thermal energy emission; an analyte target receiver that receives an analyte target, such that the analyte target receiver is in infrared communication with the infrared absorber disposed in the infrared source receiver so that the analyte target receives the thermal energy emission from the infrared absorber, desorbs the adsorbed analyte as volatilized analyte from the analyte target in response to receipt of the thermal energy emission from the infrared absorber, and communicates the volatilized analyte from the analyte target; and an effluent communicator that receives the volatized analyte.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: September 19, 2023
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Thomas Patrick Forbes, Matthew Edward Staymates
  • Patent number: 11745493
    Abstract: A process for making an ultra-conformal microprint by ultra-conformal microprint transferring includes: disposing a transfer moiety arranged in a microstructure on a transfer substrate; disposing a glassy transfer layer on the transfer moiety; forming a glassy composite; removing the glassy composite from the transfer substrate while maintaining the microstructure of the transfer moiety in the glassy transfer layer; disposing the glassy composite on a microprint substrate; ultra-conformally covering the microprint substrate with the glassy composite by heating the glassy composite so that it flows while maintaining the microstructure of the transfer moiety in the glassy transfer layer so that the microstructure is disposed on the microprint substrate; and removing the glassy transfer layer while leaving the transfer moiety disposed in the microstructure on the microprint substrate to form the ultra-conformal microprint including the transfer moiety arranged in the microstructure on the microprint substrate.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: September 5, 2023
    Assignee: GOVERNMENT OF THE THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventor: Gary Zabow
  • Patent number: 11738312
    Abstract: A multidimensional printer makes a multidimensional structure from a liquid composition and includes: an energetic crosslinking particle source; a vacuum chamber that receives energetic crosslinking particles from the energetic crosslinking particle source; a membrane that transmits the energetic crosslinking particles; and a sample chamber that: receives a liquid composition that includes a solvent and polymers, the polymers including a cross-linkable moiety subjected to the energetic crosslinking particles such that portions of the polymers proximate to the cross-linkable moieties subjected to the energetic crosslinking particles crosslink to form a solid crosslinked polymer structure, wherein the membrane isolates a vacuum of the vacuum chamber from vapor of the liquid composition in the sample chamber.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: August 29, 2023
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Andrei A. Kolmakov, Glenn Emerson Holland, Tanya Gupta
  • Patent number: 11742955
    Abstract: An operational environment is disclosed herein that includes a cryogenic environment and a signal source. The cryogenic environment includes a signal target, an optical link, signal converter devices, and an electrical link. Outside of the cryogenic environment, the signal source generates an electric signal. An electric-to-optical converter converts the electrical signal into an optical signal. The optical link delivers the optical signal into the cryogenic environment. Inside the cryogenic environment, an optical-to-electrical converter converts the optical signal back into an electrical signal. The optical-to-electrical converter transfers the electric signal to the signal target.
    Type: Grant
    Filed: May 11, 2022
    Date of Patent: August 29, 2023
    Assignees: The Regents of the University of Colorado, a body corporate, Government of the United States of America, as represented by the Secretary of Commerce
    Inventors: Florent Lecocq, Josue Davila-Rodriguez, Franklyn John Quinlan, John Teufel, Scott A. Diddams, Jose Aumentado
  • Patent number: RE49835
    Abstract: A multiplex polymerase chain reaction assay that targets nine tetranucleotide short tandem repeat (STR) markers in the mouse genome. Unique profiles were obtained from seventy-two mouse samples that were used to determine the allele distribution for each STR marker. Correlations between allele fragment length and repeat number were determined with DNA Sanger sequencing. Genotypes for L929 and NIH3T3 cell lines were shown to be stable with increasing passage numbers as there were no significant differences in fragment length with samples of low passage when compared to high passage samples. In order to detect cell line contaminants, primers for two human STR markers were incorporated into the multiplex assay to facilitate detection of human and African green monkey DNA. This multiplex assay is the first of its kind to provide a unique STR profile for each individual mouse sample and can be used to authenticate mouse cell lines.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: February 13, 2024
    Assignee: United States of America as Represented by the Secretary of Commerce
    Inventors: Jamie L Almeida, Kenneth D. Cole