Patents Assigned to Anika Research, Incorporated
  • Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use
    Patent number: 5502081
    Abstract: This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles.
    Type: Grant
    Filed: August 18, 1994
    Date of Patent: March 26, 1996
    Assignees: Research Foundation of State University of New York, Anika Research, Incorporated
    Inventors: Jing-Wen Kuo, David A. Swann, Glenn D. Prestwich