Patents Assigned to APRECIA PHARMACEUTICALS COMPANY
  • Publication number: 20170258763
    Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of water soluble drug in a porous matrix that disperses in water within a period of less than about 15 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to the drug.
    Type: Application
    Filed: May 16, 2017
    Publication date: September 14, 2017
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: JULES JACOB, NORMAN COYLE, THOMAS G. WEST, DONALD C. MONKHOUSE, HENRY L. SURPRENANT, NEMICHAND B. JAIN
  • Publication number: 20170202807
    Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of water soluble drug in a porous matrix that disperses in water within a period of less than about 15 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to the drug.
    Type: Application
    Filed: April 4, 2017
    Publication date: July 20, 2017
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: JULES JACOB, NORMAN COYLE, THOMAS G. WEST, DONALD C. MONKHOUSE, HENRY L. SURPRENANT, NEMICHAND B. JAIN
  • Publication number: 20170172919
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: February 21, 2017
    Publication date: June 22, 2017
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Patent number: 9669009
    Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of levetiracetam in a porous matrix that disperses in water within a period of less than about 15 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to levetiracetam.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: June 6, 2017
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jules Jacob, Norman Coyle, Thomas G. West, Donald C. Monkhouse, Henry L. Surprenant, Nemichand B. Jain
  • Publication number: 20170151723
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: February 2, 2017
    Publication date: June 1, 2017
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Patent number: 9616018
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: April 11, 2017
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jules Jacob, Kelly Caputo, Micael Guillot, Kenneth J. Sultzbaugh, Thomas G. West
  • Patent number: 9610735
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: April 4, 2017
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jaedeok Yoo, Thomas J. Bradbury, Thomas J. Bebb, James Iskra, Henry L. Surprenant, Thomas G. West
  • Publication number: 20160361335
    Abstract: A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The topiramate retains its taste-masked form after dispersion in the mouth of a subject even though the particles are not coated with a polymeric material. The dosage form disperses in saliva or water in less than 2 min even though it has a high content of wax. It can be used to treat diseases or disorders that are therapeutically responsive to topiramate or a derivative thereof.
    Type: Application
    Filed: August 23, 2016
    Publication date: December 15, 2016
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Lauren BEACH, Thomas G. WEST, Donald C. MONKHOUSE, Henry L. SURPRENANT
  • Patent number: 9517591
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: December 13, 2016
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jaedeok Yoo, Thomas J. Bradbury, Thomas J. Bebb, James Iskra, Henry L. Surprenant, Thomas G. West
  • Patent number: 9517592
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: December 13, 2016
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jaedeok Yoo, Thomas J. Bradbury, Thomas J. Bebb, James Iskra, Henry L. Surprenant, Thomas G. West
  • Patent number: 9492380
    Abstract: A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The topiramate retains its taste-masked form after dispersion in the mouth of a subject even though the particles are not coated with a polymeric material. The dosage form disperses in saliva or water in less than 2 min even though it has a high content of wax. It can be used to treat diseases or disorders that are therapeutically responsive to topiramate or a derivative thereof.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: November 15, 2016
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jules Jacob, Lauren Beach, Thomas G. West, Donald C. Monkhouse, Henry L. Surprenant
  • Publication number: 20160250145
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: February 17, 2016
    Publication date: September 1, 2016
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Publication number: 20160220534
    Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of levetiracetam in a porous matrix that disperses in water within a period of less than about 15 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to levetiracetam.
    Type: Application
    Filed: April 11, 2016
    Publication date: August 4, 2016
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Norman COYLE, Thomas G. WEST, Donald C. MONKHOUSE, Henry L. SURPRENANT, Nemichand B. JAIN
  • Publication number: 20160207265
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: March 22, 2016
    Publication date: July 21, 2016
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Publication number: 20160193787
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: February 18, 2016
    Publication date: July 7, 2016
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST
  • Patent number: 9339489
    Abstract: A high dose rapidly dispersing three-dimensionally printed dosage form comprising a high dose of levetiracetam in a porous matrix that disperses in water within a period of less than about 10 seconds is disclosed. Also disclosed are methods of preparing the dosage form and of treating a condition, disease or disorder that is therapeutically responsive to levetiracetam.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: May 17, 2016
    Assignee: Aprecia Pharmaceuticals Company
    Inventors: Jules Jacob, Norman Coyle, Thomas G West, Donald C. Monkhouse, Henry L. Surprenant, Nemichand B. Jain
  • Patent number: 9314429
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: April 19, 2016
    Assignee: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules Jacob, Kelly Caputo, Micael Guillot, Kenneth J. Sultzbaugh, Thomas G. West
  • Publication number: 20150366801
    Abstract: A taste-masked rapidly dispersible dosage form of topiramate is provided. Wax coated particles of topiramate are included within a porous bound matrix. The topiramate retains its taste-masked form after dispersion in the mouth of a subject even though the particles are not coated with a polymeric material. The dosage form disperses in saliva or water in less than 2 min even though it has a high content of wax. It can be used to treat diseases or disorders that are therapeutically responsive to topiramate or a derivative thereof.
    Type: Application
    Filed: August 27, 2015
    Publication date: December 24, 2015
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Lauren BEACH, Thomas G. WEST, Donald C. MONKHOUSE, Henry L. SURPRENANT
  • Publication number: 20150366802
    Abstract: A high dose orodispersible dosage form of oxcarbazepine is provided. Drug-containing particles of oxcarbazepine are included within a porous bound matrix. The dosage form disperses in saliva or water in less than 15 sec and it has sufficient hardness to withstand handling and storage. It can be used to treat diseases or disorders that are therapeutically responsive to oxcarbazepine or a derivative thereof.
    Type: Application
    Filed: August 27, 2015
    Publication date: December 24, 2015
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jules JACOB, Kelly CAPUTO, Micael GUILLOT, Kenneth J. SULTZBAUGH, Thomas G. WEST
  • Publication number: 20150183166
    Abstract: A three-dimensional printing system and equipment assembly for the manufacture of three-dimensionally printed articles is provided. The equipment assembly includes a three-dimensional printing build system, an optional liquid removal system and an optional harvester system. The build system includes a conveyor, plural build modules and at least one build station having a powder-layering system and a printing system. The equipment assembly can be used to manufacture pharmaceutical, medical, and non-pharmaceutical/non-medical objects. It can be used to prepare single or multiple articles.
    Type: Application
    Filed: September 30, 2014
    Publication date: July 2, 2015
    Applicant: APRECIA PHARMACEUTICALS COMPANY
    Inventors: Jaedeok YOO, Thomas J. BRADBURY, Thomas J. BEBB, James ISKRA, Henry L. SURPRENANT, Thomas G. WEST