Patents Assigned to Arizona Board of Regents, a body corporate of the State of Arizona
  • Publication number: 20230009041
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: April 28, 2022
    Publication date: January 12, 2023
    Applicants: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of, Consejo Superior De Investigaciones Cientificas, IPPOX Foundation
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mariano Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias Haddad, James Tartaglia
  • Patent number: 11170190
    Abstract: The disclosure features dendritic tags, and methods and systems for fabricating and using such tags. The methods can include obtaining at least one image of a dendritic tag attached to an article, analyzing the at least one image to identify a set of features associated with the dendritic tag, and comparing the set of features to stored information to identify the article.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: November 9, 2021
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: Michael N. Kozicki
  • Patent number: 10780145
    Abstract: A hydrogel (I), comprising a polymer backbone wherein an aqueous solution of the hydrogel comprises a first lower critical solution temperature, and wherein the hydrogel is configured to be converted in vivo into a modified hydrogel, and wherein an aqueous solution of the modified hydrogel comprises a second lower critical solution temperature, and wherein the second lower critical solution temperature is greater than the first lower critical solution temperature.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: September 22, 2020
    Assignees: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY, BANNER HEALTH
    Inventors: Derek Overstreet, Brent Vernon, Ryan McLemore, Alex McLaren
  • Patent number: 10724198
    Abstract: The present invention provides methods for mineral precipitation of porous particulate starting materials using isolated urease.
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: July 28, 2020
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizona State University
    Inventors: Edward Kavazanjian, Nasser Hamdan
  • Publication number: 20200172926
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: July 17, 2019
    Publication date: June 4, 2020
    Applicants: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizo, Consejo Superior De Investigaciones Cientificas, IPPOX Foundation
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mario Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias El Haddad, James Tartaglia
  • Patent number: 10539530
    Abstract: A system for analyzing a content of a sample material is presented. The system includes a fiber sensitized to a first substance, and at least one electrode configured to expose the fiber to an electric field. The system includes an optical sensor configured to detect a displacement of the fiber when the fiber is exposed to the electric field, and a processor configured to use the displacement of the fiber to characterize a content of the sample material.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: January 21, 2020
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: Nongjian Tao
  • Patent number: 10490847
    Abstract: Inorganic plastic crystal electrolytes, also referred to herein as inorganic plastic crystal conductors or single ion conductors including [ABx-yCy]y?[M]y+, where A is a tetravalent to hexavalent atom; B is a monovalent ligand; C is an oxyanion; M is an alkali metal; x is 4 when A is tetravalent, x is 5 when A is pentavalent, and x is 6 when A is hexavalent; y is an integer from 1 to x?1 inclusive. [ABx-yCy]y?[M]y+ is rotationally disordered and ionically conductive.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 26, 2019
    Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona Acting for and on Behalf of Arizona State University
    Inventors: C. Austen Angell, Iolanda Santana Klein, Telpriore Greg Tucker
  • Patent number: 10467447
    Abstract: The disclosure features dendritic tags, and methods and systems for fabricating and using such tags. The methods can include obtaining at least one image of a dendritic tag attached to an article, analyzing the at least one image to identify a set of features associated with the dendritic tag, and comparing the set of features to stored information to identify the article.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: November 5, 2019
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: Michael N. Kozicki
  • Patent number: 10407495
    Abstract: The present invention relates to therapeutic agents comprising bispecific recombinant antibody fragments to selectively clear a protein associated with a neurological disease and methods of use of these therapeutic agents to treat neurological diseases.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: September 10, 2019
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Michael Sierks, Yong Shen
  • Patent number: 10391093
    Abstract: The invention provides compounds of formulae I, II, III, and IV: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: August 27, 2019
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl E. Wagner, Peter W. Jurutka, Pamela A. Marshall
  • Patent number: 10391485
    Abstract: A microfluidic device useable for performing live cell computed tomography imaging is fabricated with a cover portion including a first wafer with at least one metal patterned thereon, a base portion including a second wafer with at least one metal patterned thereon and negative photoresist defining recesses therein, and a diffusive bonding layer including a negative photoresist arranged to join the cover portion and the base portion. A composition useful in live cell computer topography includes a long-chain polysaccharide at a concentration of from about 0.01% to about 10.0% in cell culture medium for supporting cell life while enabling cell rotation rate to be slowed to a speed commensurate with low light level imaging.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 27, 2019
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Deirdre Meldrum, Roger Johnson, Iniyan Soundappa Elango, Andrew Shabilla, Hong Wang, Jakrey Myers, Laimonas Kelbauskas, Dean Smith, Pimwadee Limsirichai
  • Patent number: 10370679
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: August 6, 2019
    Assignees: ARIZONA BOARD OF REGENTS, a body corporate of the State of Arizona acting for and on behalf of Ariz, CONSEJO SUPERIOR DE INVESTGACIONES CIENTRIFICAS, IPPOX FOUNDATION
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mariano Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias El Haddad, James Tartaglia
  • Patent number: 10223567
    Abstract: The disclosure features dendritic tags, and methods and systems for fabricating and using such tags. The methods can include obtaining at least one image of a dendritic tag attached to an article, analyzing the at least one image to identify a set of features associated with the dendritic tag, and comparing the set of features to stored information to identify the article.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: March 5, 2019
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: Michael N. Kozicki
  • Patent number: 10219918
    Abstract: A prosthetic device including an internal frame assembled from multiple longitudinal members and multiple transverse members, wherein each member is substantially planar and defines peripheral slots, and wherein the longitudinal members and transverse members are arranged to mate with one another to join the longitudinal members with the transverse members. In certain embodiments, a first group of longitudinal members is radially arranged relative to a central axis extending through the transverse members, and a second group of longitudinal members is tangentially arranged relative to the central axis, preferably with lateral edges of the second group of longitudinal members extending between two different longitudinal members of the first group of longitudinal members to provide enhanced torsional rigidity. An outer shaping member, which may be tubular in shape, may be arranged to cover at least a portion of the internal frame.
    Type: Grant
    Filed: September 6, 2016
    Date of Patent: March 5, 2019
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Jeffrey LaBelle, Sarah McBryan
  • Patent number: 10162162
    Abstract: Microfluidic devices for 3D hydrodynamic microvortical rotation of at least one live single cell or cell cluster, systems incorporating the devices, and methods of fabricating and using the devices and systems, are provided. A microfluidic chip rotates at least one live single cell or cell cluster in a microvortex about a stable rotation axis perpendicular to an optical axis within a chamber having a trapezoidal cross-sectional shape located below a flow channel. An optical trap may be used to position the cell or cells with the microvortex, and the cell or cells may be subject to live-cell or cell cluster computer tomography imaging.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: December 25, 2018
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Hong Wang, Deirdre Meldrum, Rishabh Shetty, Laimonas Kelbauskas, Shih-Hui Chao, Roger Johnson, Jakrey Myers, Samantha Chan
  • Patent number: 10156573
    Abstract: The present disclosure relates to an optical fluorescence sensor comprising a probe for sensing glucose, an intra-reference probe, and a matrix. The present disclosure also relates to an optical fluorescence dual sensor comprising a probe for sensing glucose having two boronic acid moieties, a probe for sensing oxygen comprising modified porphyrin, an intra-reference probe that is rhodamine-based, and a matrix. The present disclosure additionally relates to methods of preparing these sensors and methods of using them.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 18, 2018
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Arizona State University
    Inventors: Yanqing Tian, Liqiang Zhang, Fengyu Su, Deirdre Meldrum, Sean Buizer
  • Patent number: 10128488
    Abstract: An anode for a rechargeable battery includes a Type II clathrate having the formula MxX136, where a cage structure is formed by X, M represents one or more guest ions, and 0<x<24. When x=0, no guest ion is present in the cage structure. X may be Si, Ge, Sn, or a combination thereof. M may be an ion of Na, K, Rb, Cs, Ba, Sr, Ca, Cl, Br, I, Eu, P, Te, Li, Mg, or a combination thereof. A rechargeable battery including the anode (e.g., as an anode) includes a cathode and an electrolyte in contact with the anode and the cathode. Forming the anode may include preparing a composition including the Type II clathrate contacting the composition with a current collector to form the anode. Guest ions may be electrochemically inserted and removed from the cage structure during operation of the rechargeable battery.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: November 13, 2018
    Assignee: Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University
    Inventor: Candace Chan
  • Patent number: 10074000
    Abstract: The disclosure features dendritic tags, and methods and systems for fabricating and using such tags. The methods can include obtaining at least one image of a dendritic tag attached to an article, analyzing the at least one image to identify a set of features associated with the dendritic tag, and comparing the set of features to stored information to identify the article.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: September 11, 2018
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: Michael N. Kozicki
  • Patent number: 10046293
    Abstract: Provided herein are methods and devices for performing in situ patterned chemistry for synthesizing and preparing peptide arrays. The invention provides a reproducible and scalable platform that can be potentially used to monitor the health of a plurality of individuals.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: August 14, 2018
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA
    Inventors: Neal Woodbury, Stephen Albert Johnston
  • Patent number: 9938330
    Abstract: The present invention provides devices and methods to separate and concentrate target protein species at a microliter scale and to generate reagents to those variants with exquisite selectivity for specific protein isoforms using only picograms of target material.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: April 10, 2018
    Assignee: Arizona Board of Regents, a Body Corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
    Inventors: Michael Sierks, Mark Hayes