Patents Assigned to Axsome Malta Ltd.
  • Methods of administering solriamfetol to lactating women
    Patent number: 11771666
    Abstract: Provided herein according to some embodiments is a method for decreasing the potential for adverse events from solriamfetol in an infant fed breast milk obtained from a subject treated with solriamfetol comprising: orally administering the solriamfetol to the subject at a daily dose of about 37.5 mg to about 300 mg; and feeding the infant breast milk from the subject at least about 5 hours after administering the solriamfetol to the subject, thereby decreasing potential for adverse events from solriamfetol in an infant.
    Type: Grant
    Filed: December 30, 2022
    Date of Patent: October 3, 2023
    Assignee: Axsome Malta Ltd.
    Inventor: Herriot Tabuteau
  • Treatment of cataplexy
    Patent number: 11713292
    Abstract: The present invention relates to a method of treating cataplexy in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds.
    Type: Grant
    Filed: July 23, 2021
    Date of Patent: August 1, 2023
    Assignees: Axsome Malta Ltd, SK Biopharmaceuticals Co., Ltd.
    Inventors: Moise A. Khayrallah, Gary Bream, Stephen E. Butts
  • Methods and compositions for treating excessive sleepiness
    Patent number: 11648232
    Abstract: The present invention relates to carbamoyl phenylalaninol compounds and methods of using the same to treat disorders. The invention further relates to the development of methods for treating excessive sleepiness in a subject, e.g., due to narcolepsy or obstructive sleep apnea, with the surprising outcome that “normal” levels of wakefulness are achieved based on standard objective and subjective sleepiness tests.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: May 16, 2023
    Assignee: Axsome Malta Ltd.
    Inventors: Lawrence Patrick Carter, Yuan Lu, Katayoun Zomorodi
  • Compositions comprising (R)-2-amino-3-phenylpropyl carbamate and uses thereof
    Patent number: 11560354
    Abstract: The present invention relates to a newly identified solvate form of (R)-2-amino-3-phenylpropyl carbamate (APC) hydrochloride, a method of preparing APC hydrochloride, and methods of using the same to treat disorders. The invention further relates to methods of producing APC hydrochloride with increased purity.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: January 24, 2023
    Assignees: Axsome Malta Ltd., SK Biopharmaceuticals Co., Ltd.
    Inventor: Fionn Hurley
  • Treatment for obesity
    Patent number: 11497725
    Abstract: The present invention relates to a method for treating or preventing obesity in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds. The invention further relates to methods for reducing body weight and/or reducing food intake in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: November 15, 2022
    Assignees: Axsome Malta Ltd., SK Biopharmaceuticals Co., Ltd.
    Inventors: Moise A. Khayrallah, Gary Bream, Stephen E. Butts
  • Formulations of (R)-2-amino-3-phenylpropyl carbamate
    Patent number: 11439597
    Abstract: The present invention relates to immediate release formulations of (R)-2-amino-3-phenylpropyl carbamate and methods of using the same to treat disorders.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: September 13, 2022
    Assignee: Axsome Malta Ltd.
    Inventors: Clark Patrick Allphin, Edwin Gerard Walsh