Patents Assigned to Bausch & Lomb Incorporated
  • Patent number: 10668676
    Abstract: An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising: (a) a major amount of one or more non-silicone-containing hydrophilic monomers; (b) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group, and (c) one or more hydrophilic polymers or copolymers comprising one or more hydrophilic units and a thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (“RAFT”) agent wherein the ophthalmic device has an equilibrium water content of at least about 45 weight percent.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: June 2, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nuñez, Lynn Coullard, Daniel J. Hook, Robert B. Steffen, Daniel M. Ammon, Jennifer M. Hunt, Analuz Mark
  • Patent number: 10598955
    Abstract: The disclosure generally describes methods, systems and products relating to the development and manufacture of scleral contact lenses. A number of dimensions for the scleral lens is generated based on control points and attendant curvature parameters. Any change to one or more of the curve parameters imparts an improved anterior and posterior surface of the scleral lens and associated thickness, while undesired modifications to control points and other curve parameters remain static inasmuch as the sagittal depth component is an input parameter of the present disclosure.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: March 24, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventor: Charles H. Creighton
  • Patent number: 10596107
    Abstract: A suspension includes an ophthalmic active ingredient suspended in a formulation vehicle including a suspending agent and a non-ionic cellulose derivative. The ophthalmic active agent is present as particles having Dv90<5 ?m and Dv50<1 ?m. The suspension may be administered to a patient for treating an ophthalmic inflammatory condition.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: March 24, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Mohannad Shawer, Eric Phillips, Martin J. Coffey
  • Patent number: 10555832
    Abstract: An intraocular lens (IOL) injector assembly comprising an injector body having a shuttle reception opening defined at least in part by a first sidewall and a second sidewall, and a shuttle comprising a first wing including a first portion of a shuttle lumen wall and a second wing including a second portion of a shuttle lumen wall. The first wing and the second wing are coupled together by a hinge. When in a closed state, the first portion of the shuttle lumen wall and the second portion of the shuttle lumen wall define at least a portion of an operative shuttle lumen. The shuttle and sidewalls are configured such that the first wing and the second wing interfere with the first sidewall and the second sidewall, respectively, as the shuttle passes through the shuttle reception opening, such that the closed state of the shuttle is attained.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: February 11, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Graham W. Biddle, Jon P. Cullen, Emin Engin, Bryan M. Reed, William J. Seyboth, Moises A. Valle, Christopher E. Wagner
  • Patent number: 10434012
    Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: October 8, 2019
    Assignees: Bausch & Lomb Incorporated, Technolas Perfect Vision GMBH
    Inventors: David Haydn Mordaunt, Frieder Loesel, Gwillem Mosedale
  • Patent number: 10434011
    Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.
    Type: Grant
    Filed: January 18, 2018
    Date of Patent: October 8, 2019
    Assignees: Bausch & Lomb Incorporated, Technolas Perfect Vision GMBH
    Inventors: David Haydn Mordaunt, Frieder Loesel, Gwillem Mosedale
  • Patent number: 10274751
    Abstract: A contact lens with a toric optical zone has its anterior and posterior optical zone surfaces tilted with respect to one another to forming prism in the optical zone. Thickness profiles of the peripheral region are independent of the tilt angle between the anterior and posterior optical zone surfaces.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: April 30, 2019
    Assignee: Bausch & Lomb Incorporated
    Inventors: Kristen R. Hovinga, Anita M. Graney
  • Patent number: 10133089
    Abstract: A system and a method of cast molding toric contact lenses permits aligning first and second mold sections at multiple rotational positions. Each mold section includes a set of alignment features that engage with complementary alignment features on the other mold section.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: November 20, 2018
    Assignee: Bausch & Lomb Incorporated
    Inventors: Michael Henry Dobner, Craig A. Barrile-Josephson
  • Patent number: 10130733
    Abstract: The invention is directed to a method of cleaning and disinfecting a contact lens. The method includes instructing a consumer to disinfect their contact lens comprising the following steps: remove a contact from an eye and position the lens in a lens assembly that includes a cap member; add a disinfection solution to the lens case such that the lens is submerged in the solution upon closure of the lens case with the cap member. The disinfection solution will comprise 0.5 wt. % to 6 wt. % hydrogen peroxide or a chemical precursor of hydrogen peroxide, and a P-metal modulating compound. The presence of the P-metal modulating compound in the disinfection solution decreases the neutralization rate of the hydrogen peroxide. The disinfection system exhibits a pseudo first-order, half-life of hydrogen peroxide from 12 minutes to 30 minutes over an initial sixty minutes of neutralization following exposure of the disinfection solution to a catalyst comprising a P-metal.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: November 20, 2018
    Assignee: Bausch & Lomb Incorporated
    Inventors: Kimberly Anne Millard, Erning Xia, Suzanne F. Groemminger, Jenilee Kilbury
  • Patent number: 10076445
    Abstract: A system and method are provided for removing a natural lens and inserting an Intraocular Lens (IOL) into the lens capsule of an eye. Specifically, this is accomplished by inserting the IOL through an opening on the posterior capsule that is created using a focused laser beam. The system includes a laser unit, a detector for creating images of the interior of the eye, and a computer that controls the cooperative functions of the detector and the laser unit. Based on images of the posterior capsule provided by the detector, the computer is used to control movements of the focal point through tissue of the posterior capsule to perform Laser Induced Optical Breakdown (LIOB) on posterior capsule tissue. The result is a laser capsulotomy that creates an opening through the posterior capsule allowing the natural lens to be removed and the IOL to be implanted.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: September 18, 2018
    Assignees: BAUSCH & LOMB INCORPORATED, TECHNOLAS PERFECT VISION GMBH
    Inventors: David Haydn Mordaunt, Frieder Loesel, Gwillem Mosedale
  • Patent number: 9974692
    Abstract: A system and method for performing a femto-fragmentation procedure on tissue in the crystalline lens of an eye requires that a laser beam be directed and focused to a focal point in the crystalline lens of the eye. The focal point is then guided, relative to an axis defined by the eye, to create a segment cluster by causing Laser Induced Optical Breakdown (LIOB) of tissue in the crystalline lens. The resultant segment cluster includes a plurality of contiguous, elongated segments in the crystalline lens that are individually tapered from an anterior end-area to a posterior end-area. Specifically, this is done to facilitate the removal of individual segments from the segment cluster in the crystalline lens.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: May 22, 2018
    Assignees: BAUSCH & LOMB INCORPORATED, TECHNOLAS PERFECT VISION GMBH
    Inventors: Toh Seng Goh, Brian D. McCary, David Haydn Mordaunt, Frieder Loesel, Jochen Kandulla, Gerhard Youssefi, Werner Banghard
  • Patent number: 9943622
    Abstract: Method for minimizing the sorption of tear lipids on frequent replacement, or extended-wear, contact lenses, the method comprising (a) contacting the contact lens selected from the group consisting of senofilcon A, lotrafilcon A, lotrafilcon B, and comfilcon A B with a lens care solution for a period of at least three hours to minimize the accumulation of tear lipids on the contact lens. The lens care solution comprises 0.5 ppm to 10 ppm ?-[4-tris(2-hydroxyethyl)-ammonium chloride-2-butenyl]poly[1-dimethyl ammonium chloride-2-butenyl]-?-tris(2-hydroxyethyl) ammonium chloride; citrate, citric acid or a mixture thereof; and 0.005 wt. % to 0.05 wt. % hyaluronic acid. The method also includes (b) inserting the soaked contact lens into one's eye, and (c) repeating steps (a) and (b).
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: April 17, 2018
    Assignee: Bausch & Lomb Incorporated
    Inventors: X. Michael Liu, Joseph A. Chinn, George L. Grobe, III, E. Peter Maziarz
  • Patent number: 9943439
    Abstract: A combination of an irrigation sleeve 20 and a phacoemulsification needle 22. The irrigation sleeve 20 has a proximal end 32 and a distal end 30, the proximal end for attachment to a surgical handpiece. The phacoemulsification needle 22 has a proximal end 26, a distal end 24, and a lumen 38 spanning a length of the needle 22 from the proximal end 26 to the distal end 24. The needle proximal end 26 is for connection to the surgical handpiece, and the needle 22 has structure 44 proximate the needle distal end 24 for retaining the sleeve distal end 30 near the needle distal end 24.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: April 17, 2018
    Assignee: Bausch & Lomb Incorporated
    Inventors: James T. Perkins, Anthony K. Lewis
  • Patent number: 9931242
    Abstract: An intraocular lens (IOL) injector assembly comprising an injector body having a shuttle reception opening defined at least in part by a first sidewall and a second sidewall, and a shuttle comprising a first wing including a first portion of a shuttle lumen wall and a second wing including a second portion of a shuttle lumen wall. The first wing and the second wing are coupled together by a hinge. When in a closed state, the first portion of the shuttle lumen wall and the second portion of the shuttle lumen wall define at least a portion of an operative shuttle lumen. The shuttle and sidewalls are configured such that the first wing and the second wing interfere with the first sidewall and the second sidewall, respectively, as the shuttle passes through the shuttle reception opening, such that the closed state of the shuttle is attained.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: April 3, 2018
    Assignee: Bausch & Lomb Incorporated
    Inventors: Graham W. Biddle, Jon P. Cullen, Emin Engin, Bryan M. Reed, William J. Seyboth, Moises A. Valle, Christopher E. Wagner
  • Patent number: 9895056
    Abstract: An ophthalmic laser illuminator 10 includes multiple laser devices 12-16. There are at least three different wavelengths of light emitted by the multiple laser devices 12-16 and each wavelength of light emitted by each laser device is outside of wavelengths blocked by a safety filter used for surgical treatment lasers 52. A controller 18 controls the multiple laser devices 12-16. A graphical user interface 32 is operably attached to the controller 18 for allowing a user to select a plurality of light parameters for a light beam exiting the illuminator 10.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: February 20, 2018
    Assignee: Bausch & Lomb Incorporated
    Inventors: David K. Klaffenbach, Brian McCary, John Goewert, David H. Mordaunt
  • Patent number: 9775802
    Abstract: A process for producing a pharmaceutical suspension that comprises an active pharmaceutical ingredient (“API”) having low solubility, the process comprises: (a) preparing a first solution comprising a carboxy-containing vinyl polymer and a solvent; and (b) adding a compound of the API to said first solution under conditions of high-shear mixing for a time from about 5 minutes to about 5 hours, said compound being soluble in said solvent, thereby producing a suspension of particles of said API in a composition comprising said carboxy-containing vinyl polymer; wherein a concentration of said API in said suspension is higher than a solubility of said API in said solvent. The present invention also provides a suspension produced by such process.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: October 3, 2017
    Assignee: Bausch & Lomb Incorporated
    Inventors: Steven K. MacLeod, Daniel J. Stein, James Donald Hayes, Donald L. Herber
  • Patent number: 9592157
    Abstract: A system and method for performing a femto-fragmentation procedure on tissue in the crystalline lens of an eye requires that a laser beam be directed and focused to a focal point in the crystalline lens of the eye. The focal point is then guided, relative to an axis defined by the eye, to create a segment cluster by causing Laser Induced Optical Breakdown (LIOB) of tissue in the crystalline lens. The resultant segment cluster includes a plurality of contiguous, elongated segments in the crystalline lens that are individually tapered from an anterior end-area to a posterior end-area. Specifically, this is done to facilitate the removal of individual segments from the segment cluster in the crystalline lens.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: March 14, 2017
    Assignees: BAUSCH & LOMB INCORPORATED, TECHNOLAS PERFECT VISION GMBH
    Inventors: Toh Seng Goh, Brian D. McCary, David Haydn Mordaunt, Frieder Loesel, Jochen Kandulla, Gerhard Youssefi, Werner Banghard
  • Patent number: 9527617
    Abstract: A packaging system for the storage of an ionic, hydrogel contact lens employs an aqueous packaging solution including a phosphorylcholine polymer. Preferably, the solution has an osmolality of at least about 200 mOsm/kg, a pH of about 6 to about 8 and is heat sterilized.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: December 27, 2016
    Assignee: Bausch & Lomb Incorporated
    Inventor: Fang Zhao
  • Patent number: 9498377
    Abstract: An ophthalmic surgical device (10) includes a housing (12) having a distal end (14) and a proximal end (16). A cannula (18) is attached to the housing distal end (14) and has a distal tip (20) with at least one port (22) in communication with a lumen (19) extending through the cannula (18) and in communication with an aspiration path (24) in the housing (12). A vibration source (26) is held within the housing (12) for vibrating the distal tip (20) for assisting in vitreous and other tissue removal. An aspiration source (152) connected to the aspiration path (24) for applying a negative pressure to the lumen (19) and the at least one port (22) for removing fluids and the vitreous and other tissue from the eye. The vibration source (26) and the aspiration source (152) together create a periodic bi-directional flow of tissue through the port (22) without creating cavitation externally of the distal tip (20).
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: November 22, 2016
    Assignee: Bausch & Lomb Incorporated
    Inventors: Brian D. McCary, Toh Seng Goh, James Taylor Perkins
  • Patent number: 9481856
    Abstract: A pharmaceutical formulation that is effective in adversely affecting the viability of microorganisms or in inhibiting their growth and that provides better safety and/or comfort to the users comprises a polysaccharide, a source of hydrogen peroxide, and an anti-oxidant. The formulation can further comprise a chelating agent and/or an ophthalmically active agent for treating or controlling a disease or disorder of the eye. The formulation may be used to treat, clean, disinfect, store, wet, or rewet contact lenses.
    Type: Grant
    Filed: May 19, 2009
    Date of Patent: November 1, 2016
    Assignee: Bausch & Lomb Incorporated
    Inventors: Erning Xia, Michael E. Allen, Steven K. MacLeod, Tammy J. Kleiber, Craig M. Cody