Patents Assigned to Bausch & Lomb Incorporated
  • Patent number: 11414501
    Abstract: The present invention relates to a method of and an apparatus for extending the shelf life of an initiated monomer mixture, the method comprising the prevention of premature free radical polymerisation by introducing oxygen or oxygen-containing gas into a container of the initiated monomer mixture and providing mechanical agitation to the container, wherein said introduction and agitation are performed in a temperature and pressure controlled environment.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 16, 2022
    Assignee: Bausch & Lomb Incorporated
    Inventors: Sean Lyons, Joseph Dowling, John Flynn, X. Michael Liu, E. Peter Maziarz
  • Patent number: 11391964
    Abstract: The disclosure generally describes methods, systems and products relating to the development and manufacture of scleral contact lenses. A number of dimensions for the scleral lens is generated based on control points and attendant curvature parameters. Any change to one or more of the curve parameters imparts an improved anterior and posterior surface of the scleral lens and associated thickness, while undesired modifications to control points and other curve parameters remain static inasmuch as the sagittal depth component is an input parameter of the present disclosure.
    Type: Grant
    Filed: March 23, 2020
    Date of Patent: July 19, 2022
    Assignee: Bausch & Lomb Incorporated
    Inventor: Charles H. Creighton
  • Patent number: 11345773
    Abstract: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more non-bulky organosilicon-containing monomers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: May 31, 2022
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nuñez, Lynn Coullard, Analuz Mark, Andrew J. Hoteling, Joseph W. Hoff
  • Patent number: 11344404
    Abstract: An intraocular lens includes a base refractive structure having anterior and posterior surfaces that are shaped for producing a first optical power and a diffractive structure formed in one of the surfaces of the base refractive structure including overlapping first and second diffractive patterns over a common aperture for producing second and third optical powers. The second optical power is an uneven division of the third optical power. The first and second diffractive patterns have respective step heights that are separately varied as a function of radial distance from the optical axis over the common aperture.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: May 31, 2022
    Assignee: Bausch & Lomb Incorporated
    Inventors: Nivedan Tiwari, Krishnakumar Venkateswaran, Andrew William Jones, Chun Zhan, Lorenzo Salvatori
  • Patent number: 11285681
    Abstract: Exemplary embodiments of the present disclosure provide a method and apparatus for forming an ophthalmic lens. An exemplary method includes providing a plurality of posterior tools each having a posterior optic defining surface and a plurality of anterior tools each having an anterior optic defining surface, wherein each one of the plurality of posterior tools has a different central posterior optic defining surface including a unique conic section. The method further includes selecting one of the plurality of posterior tools and one of the plurality of anterior tools based on a criteria, and forming a posterior mold by the selected one of the plurality of posterior tools and an anterior mold by the selected one of the plurality of anterior tools, the posterior mold and the anterior mold operable to form an ophthalmic lens having the criteria.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: March 29, 2022
    Assignee: Bausch & Lomb Incorporated
    Inventor: Kevin J. Fahy
  • Patent number: 11278395
    Abstract: A shuttle, vial and injector are provided for storing and presenting an IOL to a patient. The shuttle includes operably engaged shuttle plates having a set of confronting surfaces that flex about a flexure interface between a storage configuration, with at least an optic of an IOL in a nominal state and a loading configuration, with at least an optic of an IOL in a deformed state. The vial engages the shuttle and maintains the shuttle in the storage configuration. The injector receives the shuttle from the vial and includes surfaces for flexing the portions of the shuttle plates to the loading configuration upon engagement with the injector, wherein the shuttle plates impart a predetermined curvature to at least a portion of the IOL.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: March 22, 2022
    Assignee: BAUSCH & LOMB INCORPORATED
    Inventors: Moises A. Valle, Madhu S. Ayyagari, Sushant P. Muchhala, Sanjeev Bakshi
  • Patent number: 11253625
    Abstract: A packaging system for storing ophthalmic devices such as contact lenses and methods for packaging such ophthalmic devices with solutions is disclosed. The packaging system contains an unused, ophthalmic device in an aqueous packaging solution comprising tris(hydroxymethyl)aminomethane or a salt thereof; wherein the solution has an osmolality of at least about 200 mOsm/kg and a pH in the range of about 6 to about 9.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: February 22, 2022
    Assignee: Bausch & Lomb Incorporated
    Inventors: Alok Kumar Awasthi, Erning Xia, Jennah L. Wolcott, Ruth Julian
  • Patent number: 11066530
    Abstract: A method for preparing an ophthalmic device containing an ultraviolet (UV) blocker is disclosed. The method involves (a) soaking an ophthalmic device in one or more first solvent solutions to swell the ophthalmic device; (b) soaking the swelled ophthalmic device in one or more second solvents solutions comprising a UV blocker to de-swell the ophthalmic device and entrap the UV blocker in the ophthalmic device, wherein the UV blocker is a benzotriazole and (c) sterilizing the de-swelled ophthalmic device.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: July 20, 2021
    Assignee: Bausch & Lomb Incorporated
    Inventors: James Anthony DiBella, Jr., George L. Grobe, III, Alok Kumar Awasthi
  • Patent number: 11058691
    Abstract: This invention provides a method of lowering intraocular pressure in a patient having normal tension glaucoma, comprising contacting an eye of a subject having normal tension glaucoma with a pharmaceutical composition comprising an effective amount of Nitric Oxide releasing prostaglandin derivatives of formula (I).
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: July 13, 2021
    Assignees: Nicox S.A., Bausch & Lomb Incorporated
    Inventors: Jason Lamar Vittitow, Megan Elizabeth Cavet
  • Patent number: 11022722
    Abstract: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more organosilicon-containing block copolymers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 1, 2021
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nuñez, Katie L. Poetz, Lynn Coullard, Alok Kumar Awasthi, Analuz Mark, Joseph W. Hoff, Andrew J. Hoteling
  • Patent number: 10987246
    Abstract: An ophthalmic surgical device includes a housing having a distal end and a proximal end. A cannula is attached to the housing distal end and has a distal tip with at least one port in communication with a lumen extending through the cannula and in communication with an aspiration path in the housing. A vibration source is held within the housing for vibrating the distal tip of the cannula for assisting in vitreous and other tissue removal from a patient's eye. The vibration source creates a peak velocity of the distal tip equal to or less than a potential maximum flow velocity of water through the at least one port for a pressure differential between an intraocular pressure of the eye and a pressure within the cannula lumen that is less than the intraocular pressure.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: April 27, 2021
    Assignee: Bausch & Lomb Incorporated
    Inventors: Brian D. McCary, Toh Seng Goh, James Taylor Perkins
  • Patent number: 10932948
    Abstract: A phacoemulsification needle includes a hub for connection to an ultrasonic handpiece. An elongated shaft is formed with the hub and extends from the hub. A distal end of the shaft breaks-up tissue when the distal end is caused to be vibrated by the handpiece. At least a distal portion of the shaft is formed of a material that has properties providing advantages compared to a metal needle. Example properties include a substantially lower density, a substantially higher electrical resistivity, a substantially lower thermal conductivity, a substantially lower mechanical lateral stiffness, a substantially higher efficiency of converting electrical energy powering the handpiece into motion of the distal end, a substantially lower acoustical impedance, a substantially higher Poisson's ratio, and a substantially higher mechanical gain.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: March 2, 2021
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ala Moradian, Brian D. McCary, Toh Seng Goh, Matthew J. Fitzgerald
  • Patent number: 10870731
    Abstract: A method is disclosed which involves the steps of (a) reacting a polysiloxane prepolymer having reactive functional end groups with a non-free radical polymerizable reactive end-capping agent; and (b) reacting the reaction product of step (a) with a free radical polymerizable reactive end-capping agent.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: December 22, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nuñez, Katie L. Poetz, Andrew J. Hoteling, Joseph W. Hoff, Lynn Coullard, Analuz Mark, Keyla M. Cubi, Joseph A. McGee
  • Patent number: 10816698
    Abstract: An ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) a major amount of one or more first non-silicone-containing hydrophilic monomers; (b) one or more hydrophobic monomers; and (c) a crosslinking agent mixture comprising (i) one or more di-, tri- or tetra(meth)acrylate-containing crosslinking agents and (ii) one or more di-, tri- or tetracarbamate-containing crosslinking agents, wherein the ophthalmic device has an equilibrium water content of at least about 65 weight percent.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: October 27, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nuñez, Katie L. Poetz, Joseph W. Hoff, Judith Chapman Morgan
  • Patent number: 10736841
    Abstract: Novel compositions including bepotastine besilate and a corticosteroid are provided, compositions including at least about 0.008% w/v benzalkonium chloride, and compositions including hydroxypropylmethyl cellulose E15 LV.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: August 11, 2020
    Assignee: BAUSCH & LOMB INCORPORATED
    Inventors: Angel Padilla, George Baklayan
  • Patent number: 10722346
    Abstract: A shuttle, vial and injector are provided for storing and presenting an IOL to a patient. The shuttle includes operably engaged shuttle plates having a set of confronting surfaces that flex about a flexure interface between a storage configuration, with at least an optic of an IOL in a nominal state and a loading configuration, with at least an optic of an IOL in a deformed state. The vial engages the shuttle and maintains the shuttle in the storage configuration. The injector receives the shuttle from the vial and includes surfaces for flexing the portions of the shuttle plates to the loading configuration upon engagement with the injector, wherein the shuttle plates impart a predetermined curvature to at least a portion of the IOL.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: July 28, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Moises A. Valle, Madhu S. Ayyagari, Sr., Sushant P. Muchhala, Sanjeev Bakshi
  • Patent number: 10716706
    Abstract: A system and method are provided for fragmenting a crystalline lens, to facilitate its removal from the lens bag during an ophthalmic laser surgery. First, a predetermined pattern is used to make Laser Induced Optical Breakdown (LIOB) cuts that section the lens into asymmetrical, operational segments. At least one operational segment is then selected and softened with a plurality of compact LIOB cuts. Once softened, the selected segment is aspirated. The remaining operational segments are then subsequently removed. During a procedure, an imaging unit can monitor movements of the lens bag to ensure proper placement of the LIOB cuts on the lens.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: July 21, 2020
    Assignees: BAUSCH & LOMB INCORPORATED, TECHNOLAS PERFECT VISION GMBH
    Inventors: Frieder Loesel, Jochen Kandulla, Friedrich Moritz, Gwillem Mosedale, Holger Schlueter, Roland Toennies, Gerhard Youssefi, David Haydn Mordaunt
  • Patent number: 10668676
    Abstract: An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising: (a) a major amount of one or more non-silicone-containing hydrophilic monomers; (b) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group, and (c) one or more hydrophilic polymers or copolymers comprising one or more hydrophilic units and a thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (“RAFT”) agent wherein the ophthalmic device has an equilibrium water content of at least about 45 weight percent.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: June 2, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nuñez, Lynn Coullard, Daniel J. Hook, Robert B. Steffen, Daniel M. Ammon, Jennifer M. Hunt, Analuz Mark
  • Patent number: 10596107
    Abstract: A suspension includes an ophthalmic active ingredient suspended in a formulation vehicle including a suspending agent and a non-ionic cellulose derivative. The ophthalmic active agent is present as particles having Dv90<5 ?m and Dv50<1 ?m. The suspension may be administered to a patient for treating an ophthalmic inflammatory condition.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: March 24, 2020
    Assignee: Bausch & Lomb Incorporated
    Inventors: Mohannad Shawer, Eric Phillips, Martin J. Coffey
  • Patent number: D946800
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: March 22, 2022
    Assignee: Bausch & Lomb Incorporated
    Inventor: Michael J. Shannon