Patents Assigned to Ben-Gurion University of the Negev Research and Development Authority
  • Patent number: 9147246
    Abstract: A method of analyzing a stream of imaging data is disclosed. The method comprises: for each picture-element of the data, associating a vector of features indicative of temporal intensity variation relative to baseline intensity, thereby providing a plurality of vectors. The method further comprises clustering the picture-elements according to the vectors, thereby providing a plurality of clusters, and identifying different compartments in the vasculature based on the clusters.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: September 29, 2015
    Assignees: Ben-Gurion University of the Negev Research and Development Authority, Mor Research Applications Ltd.
    Inventors: Alon Friedman, Yoash Chassidim, Ofer Prager, Ilan Shelef
  • Patent number: 9138498
    Abstract: Provided are a method and an apparatus for modifying particle size of powders in closed items, comprising the exposure of said items to external electric field of suitable parameters. The degree of agglomeration of the particles can be increased or decreased. Applications to neutralization of harmful powders in mails, to dry agglomeration and to volatilization of powders in food industry and in pharmacology are described.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: September 22, 2015
    Assignee: Ben-Gurion University of the Negev Research & Development Authority
    Inventor: Sergey Biryukov
  • Patent number: 9134056
    Abstract: An air-cooled absorption refrigerating system and method is provided An evaporated refrigerant is mixed with a weak refrigerant stream Portions of the evaporated refrigerant are absorbed into the weak refrigerant stream via air-cooled absorber means to form a reconstituted solution which is pumped into heater means in heat exchange relationship with a hot weak refrigerant. The hot weak refrigerant stream is conducted therefrom Refrigerant is evaporated from the reconstituted solution via generator means in heat exchange relationship with a heat transfer fluid The generator means stream is separated into a hot weak refrigerant stream and a main refrigerant vapor stream The main refrigerant vapor stream is condensed via air-cooled condenser means The pressure of a condensed refrigerant vapor stream is reduced and conducted into evaporator means, where it is evaporated to form an evaporated refrigerant stream and conducted therefrom.
    Type: Grant
    Filed: September 6, 2010
    Date of Patent: September 15, 2015
    Assignee: Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Avi Levy, Michael Jelinek, Irene Borde
  • Patent number: 9127254
    Abstract: The present invention relates to bioresorbable scaffolding for tissue regeneration or repair. The present invention describes an epithelial organoid comprising an aggregate of epithelial cells predominantly expressing markers associated with differentiated cell types, and an aggregate which assumes a structure or performs a function associated with an epithelial organ or a fragment thereof. The present invention also provides a method of treating a subject in need of repair or replacement of an organ or a portion thereof; and/or a method of treating a subject with a disease or disorder which impairs or abrogates a liver, kidney, pancreas, thyroid or pituitary function. The present invention also describes an epithelial graft or artificial organ comprising spheroids, organoids or a combination thereof, and a kit for implantable epithelial graft formation comprising organoids.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: September 8, 2015
    Assignee: Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Smadar Cohen, Mona Dvir-Ginzberg
  • Publication number: 20150246141
    Abstract: Highly sensitive imaging of diseased tissues such as cancer is attractive because it potentially allows for early tumor detection. One of the problems associated with conventional, low molecular weight imaging probes is the limited tumor: background ratio. To circumvent this, imaging probes were conjugated to polymeric carriers and were surprisingly found to accumulate specifically at cancer sites. This invention describes an innovative targeting strategy for the selective identification of solid tumors by means of polymer-NIR fluorochrome conjugates which accumulate selectively within cancerous tissue relative to normal tissue.
    Type: Application
    Filed: September 12, 2013
    Publication date: September 3, 2015
    Applicant: Ben-Gurion University of the Negev Research and Development Authority
    Inventor: Ayelet David
  • Patent number: 9119870
    Abstract: A joint-lubricating composition for treating degenerative joint disorders is provided, having microalgal polysaccharides in an aqueous solution, wherein the polysaccharides are stable and non-immunogenic. Further provided is a method for treating a joint disorder by injecting into the joint a viscous aqueous solution of a polysaccharide, wherein the disorder is, for example, arthritis, and the polysaccharide originates, for example, from a red alga.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: September 1, 2015
    Assignee: Ben Gurion University of the Negev Research and Development Authority
    Inventors: Shosh Arad, Dan Atar
  • Patent number: 9079152
    Abstract: The invention provides a process for the preparation of essential oil microcapsules comprising dissolving a di- or polyisocyanate into an essential oil, emulsifying the resulting mixture in an aqueous solution containing a di- or polyamine, and or a di or polyhydroxy compound to effect encapsulation of said essential oil through interfacial polymerization, whereby there is formed a polyurea and/or polyurethane film around the essential oil droplets which film enhances the stability of said essential oil, reduces its evaporation rate and controls its release rate when applied to a substrate.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: July 14, 2015
    Assignee: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
    Inventors: Arie Markus, Charles Linder
  • Patent number: 9079966
    Abstract: The present invention discloses a process for the preparation of a Poly-ubiquitin chain, this process comprising ligating a Ubiquitin thioester Ubm-SR with a Ubiquitin Ubq. Further are disclosed poly-ubiquitin chains prepared according to this process, in particular poly-ubiquitin chains containing at least one unnatural amino acid.
    Type: Grant
    Filed: February 9, 2011
    Date of Patent: July 14, 2015
    Assignee: BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
    Inventors: Ashraf Brik, Mahmood Haj-Yahya, Ajish Kumar, Leslie Erlich, Liat Spasser
  • Patent number: 9056079
    Abstract: This invention provides derivatives of dodecapeptide ISSIKEKYPSHS (SEQ ID NO: 11) which interfere with binding of calbindin to inositol monophosphatase, and their use in treating mood disorders.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: June 16, 2015
    Assignee: Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Galila Agam, Orna Almog, Itzchak Levi, Yael Eskira, Yuly Bersudsky
  • Patent number: 9058736
    Abstract: Apparatus for detection of human falls comprises: an acceleration detector, for detecting vibration events, typically placed on a floor, a microphone, located in association with the acceleration detector for detection of corresponding sound events, and a classification unit to classify concurrent events from the microphone and the acceleration detector, thereby to determine whether a human fall is indicated. If the event appears to be a human fall, then an alarm is raised.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: June 16, 2015
    Assignees: Ramot at Tel-Aviv University Ltd., Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Israel Gannot, Dimitry Litvak, Yaniv Zigel
  • Patent number: 9049850
    Abstract: Nucleic acid molecules encoding an insulin-like factor of the androgenic gland of the freshwater prawn Macrobrachium rosenbergii (M. rosenbergii) are disclosed. Also disclosed are methods of silencing the expression of the insulin-like factor gene in decapod crustaceans order, particularly in M. rosenbergii, useful for producing male monosex populations.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: June 9, 2015
    Assignee: Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Amir Sagi, Tomer Ventura
  • Publication number: 20150119741
    Abstract: A method of distinguishing sleep period states that a person experiences during a sleep period, the method comprising: using a non-contact microphone to acquire a sleep sound signal representing sounds made by a person during sleep; segmenting the sleep sound signals into epochs; generating a sleep sound feature vector for each epoch; providing a first model that gives a probability that a given sleep period state experienced by the person in a given epoch exhibits a given sleep sound feature vector; providing a second model that gives a probability that a first sleep period state associated with a first epoch transitions to a second sleep period state associated with a subsequent second epoch; and processing the feature vectors using the first and second models to determine a sleep period state of the person from a plurality of possible sleep period states for each of the epochs.
    Type: Application
    Filed: May 30, 2013
    Publication date: April 30, 2015
    Applicant: BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
    Inventors: Yaniv Zigel, Eliran Dafna, Ariel Tarasiuk
  • Patent number: 9008311
    Abstract: A communication system that includes a sender computer and plurality of designated receiver computers coupled to the sender through a communication link. Each one of the receiver computers is equipped with computational resources stronger than the computational resources of an adversary computer. There is provided a method for sending a secret from the sender computer to a designated receiver computer. The sender computer defining a succession of computational tasks having respective solutions. The computational tasks are so defined such that the duration of solving each task by the receiver computer is shorter than what would have been required for the adversary computer to solve the task. Next, the sender computer sending through the link the succession of tasks encrypted by previous solutions and the receiver computer receiving the tasks and is capable of decrypting the secret faster than what would have been required for the adversary computer to decrypt the secret.
    Type: Grant
    Filed: June 23, 2005
    Date of Patent: April 14, 2015
    Assignee: Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Shlomi Dolev, Ephraim Korach, Galit Uzan
  • Patent number: 9006213
    Abstract: A therapeutic composition for treatment of a body tissue which includes an aqueous solution of a cross-linked polymer being capable of: (i) maintaining a liquid state in storage at room temperature for at least 24 hours; and (ii) assuming a gel state following deposition within the body tissue. The therapeutic composition can be effectively administered into a damaged body tissue via injection or catheterization, thereby treating the damaged body tissue.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: April 14, 2015
    Assignee: Ben Gurion University of the Negev Research and Development Authority
    Inventors: Smadar Cohen, Jonathan Leor
  • Patent number: 8999134
    Abstract: Provided is a method for the electrochemical conversion of carbon dioxide to fuels. The method employs reducing CO2 in an electrochemical cell using an aerogel carbon electrode and an ionic liquid membrane, thereby providing a carbon-based combustible.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: April 7, 2015
    Assignee: Ben-Gurion University of the Negev Research & Development Authority, Ltd.
    Inventors: Armand Bettelheim, Eli Korin
  • Patent number: 8993538
    Abstract: A therapeutic composition for treatment of a body tissue which includes an aqueous solution of a cross-linked polymer being capable of: (i) maintaining a liquid state in storage at room temperature for at least 24 hours; and (ii) assuming a gel state following deposition within the body tissue. The therapeutic composition can be effectively administered into a damaged body tissue via injection or catheterization, thereby treating the damaged body tissue.
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: March 31, 2015
    Assignee: Ben Gurion University of the Negev Research and Development Authority
    Inventors: Smadar Cohen, Jonathan Leor
  • Patent number: 8980244
    Abstract: The invention relates to use of the natural cytotoxicity receptor NKp46 for preventing and treating diabetes, including type I diabetes (TID) and type 2 diabetes. In particular, the invention provides compositions comprising a fragment of the extracellular region of NKp46 for preventing the onset and progression of diabetes.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: March 17, 2015
    Assignees: Ben-Gurion University of the Negev Research and Development Authority, Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd.
    Inventors: Ofer Mandelboim, Angel Porgador, Yaakov Naparstek, Chamutal Gur
  • Patent number: 8968161
    Abstract: Apparatus for exercising a person's balance control, the apparatus comprising: a motion stage operable to displace an object mounted thereto; a treadmill mounted to the stage and comprising a belt having a runway surface on which a person using the treadmill stands, walks and/or runs; and a controller that controls the motion stage to provide a displacement of the treadmill and thereby the treadmill runway surface.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: March 3, 2015
    Assignee: Ben Gurion University of the Negev Research and Development Authority
    Inventors: Amir Shapiro, Itshak Melzer, Allan C. Entis
  • Patent number: 8953648
    Abstract: The invention is an apparatus and method for free space pumping of active double-clad fiber based lasers and amplifiers. The apparatus comprises a laser emitting a signal laser beam; an active double-clad fiber having a core defining an optical axis of the apparatus and a pump cladding defining a cone of numerical aperture; an optical arrangement directing the signal laser beam along the optical axis through the core of the active double-clad fiber; at least one pump source emitting a pump beam; at least one delivery means coupling the pump beam to the pump cladding of the active double-clad fiber; and an optical arrangement coupling the amplified signal laser beam exiting the active double-clad fiber out of the apparatus.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: February 10, 2015
    Assignee: Ben-Gurion University of the Negev Research & Development Authority
    Inventors: Amiel Ishaaya, Boris Shulga
  • Patent number: 8936930
    Abstract: A method of transforming red microalgae is provided. The method is effected by: (i) culturing red microalgae cells under predetermined light/dilution conditions to thereby generate competent red microalgae cells; and (ii) introducing at least one exogenous polynucleotide into said competent red microalgae cells, thereby transforming the red microalgae.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: January 20, 2015
    Assignees: Ben-Gurion University of the Negev Research and Development Authority, Mor Research Applications Ltd.
    Inventors: Shoshana Arad, Miri Lapidot, Yacob Weinstein, Ron Dagan