Patents Assigned to Board of Regents The University of Texas System
  • Patent number: 10691095
    Abstract: Methods and systems for diagnosing and controlling material deposition during a material extrusion 3D printing process. A current sensor can measure a current signal consumed by a material feed motor. The current signal can be analyzed in the time domain and frequency domain to detect material deposition characteristics and prescribe process parameter changes.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: June 23, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Chi Yen Kim, David Espalin, Eric MacDonald, Ryan Wicker
  • Patent number: 10687520
    Abstract: Duchenne muscular dystrophy (DMD), which affects 1 in 5,000 male births, is one of the most common genetic disorders of children. This disease is caused by an absence or deficiency of dystrophin protein in striated muscle. The major DMD deletion “hot spots” are found between exon 6 to 8, and exons 45 to 53. Here, a “humanized” mouse model is provided that can be used to test a variety of DMD exon skipping strategies. Among these are, CRISPR/Cas9 oligonucleotides, small molecules or other therapeutic modalities that promote exon skipping or micro dystrophin mini genes or cell based therapies. Methods for restoring the reading frame of exon 44 deletion via CRISPR-mediated exon skipping in the humanized mouse model, in patient-derived iPS cells and ultimately, in patients using various delivery systems are also contemplated. The impact of CRISPR technology on DMD is that gene editing can permanently correct mutations.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: June 23, 2020
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Yi-Li Min, Rhonda Bassel-Duby, Eric Olson
  • Publication number: 20200188396
    Abstract: Certain embodiments are directed to methods of treating or preventing an addictive behavior in a subject by administering to the subject an effective amount of a 5-HT2C receptor agonist in combination with a DA D3/D4 receptor antagonist.
    Type: Application
    Filed: April 27, 2018
    Publication date: June 18, 2020
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Charles France, Gregory Collins
  • Publication number: 20200189933
    Abstract: Disclosed are a desalination device and processes of desalination using the device. The device is directly ocean-situated and fully nature-powered with on intake, no brine production, and no electricity consumption. The device contains a heating unit, configured to receive a dry air stream and heat the dry air stream with one or more renewable energy sources to produce a heated air stream; a humidifier, configured to receive the heated air stream, evaporate at least portion of water present in the humidifier and humidify the heated air stream to produce a wet air stream, a cooling unit, configured to receive the wet stream and cool the wet air stream resulting in condensation of at least a portion of the moisture to produce fresh water and a dehumidified air stream; and a fresh water collection tank, configured to collect at least a portion of the fresh water.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 18, 2020
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventor: Yingchen Yang
  • Publication number: 20200190204
    Abstract: Provided herein are BAFF-R antibodies as well as compositions and methods of making and using the same. The antibodies provided herein are, inter alia, useful for the treatment of cancer and autoimmune diseases.
    Type: Application
    Filed: June 6, 2017
    Publication date: June 18, 2020
    Applicants: CITY OF HOPE, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Hong QIN, Larry W. KWAK, Jingxing LI, Kexin HUANG
  • Publication number: 20200191127
    Abstract: Actuators (artificial muscles) comprising twist-spun nanofiber yarn or twist-inserted polymer fibers generate torsional actuation when powered electrically, photonically, chemically, thermally, by absorption, or by other means. These artificial muscles utilize coiled yarns/polymer fibers and can be either neat or comprising a guest. In some embodiments, the actuator system includes a twisted and coiled polymer fiber actuator, and at least one of (i) wire connections that enable electrical heating of the twisted and coiled polymer fiber actuator, (ii) a radiation source and radiation pathway that enables photothermal heating of the twisted and coiled polymer fiber actuator, and (iii) a delivery system for delivering chemicals whose reaction produces heating of the twisted and coiled polymer fiber actuator.
    Type: Application
    Filed: October 9, 2019
    Publication date: June 18, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Na Li, Carter S. Haines, Marcio D. Lima, Monica Jung DeAndrade, Shaoli Fang, Jiyoung Oh, Mikhail E. Kozlov, Dongseok Suh, Ray H. Baughman
  • Patent number: 10682077
    Abstract: Devices and methods for detecting joint motion of a user. In particular embodiments, devices may comprise a deflectable beam coupled to a user via adhesive pads located between the neck and shoulder of the use. Audio and haptic feedback can be provided to the user when the deflectable beam deflects due to motion of the joint.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: June 16, 2020
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, SETON HEALTHCARE FAMILY
    Inventors: James S. Sulzer, Jose J. Mendez, Jr., Nicholas D. Phillips, Lisa Stevens, Curtis Merring
  • Patent number: 10682388
    Abstract: The disclosure describes PELP1 binding peptides and peptoids and their use the interaction of PELP1 with molecules that lead to oncogenic signaling in cancers.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: June 16, 2020
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Ratna K. Vadlamudi, Monica Mann, Samaya Krishnan, Gangadhara Reddy Sareddy
  • Patent number: 10683366
    Abstract: The present invention provides methods and compositions for treating atherosclerosis in a subject comprising the use of therapeutic compounds to reduce Reelin in the circulation of the subject, thereby reducing the adhesion of leukocytes to the vascular wall. The invention also provides methods and compositions for reducing leukocyte adhesion to the vascular wall in a subject.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: June 16, 2020
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Joachim Herz, Yinyuan Ding, Xunde Xian, Linzhang Huang, Chieko Mineo, Philip Shaul, Laurent Calvier
  • Patent number: 10683582
    Abstract: In some embodiments, an anti-corrosive composite ceramic coating includes an inner metal layer formed on the surface of a metal object to be protected and an outer composite ceramic layer formed on the inner metal layer.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 16, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: George Kenneth Rice, Miguel Jose Yacaman, Ekaterina Vinogradova
  • Patent number: 10687329
    Abstract: Various examples are provided for coherence diversity. In one example, a method includes receiving a product signal transmitted over a plurality of subcarriers, the product signal including a product superposition of a first baseband signal and a second baseband signal; estimating equivalent channel responses for the plurality of subcarriers based upon the pilot symbol in the number of time slots of the plurality of subcarriers; and decoding the second encoded message based at least in part upon the first baseband signal and the equivalent channel responses. The first baseband signal can include a pilot symbol in a number of time slots of at least a portion of the plurality of subcarriers and a first encoded message in a remaining number of time slots of the plurality of subcarriers, and the second baseband signal can include a second encoded message.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: June 16, 2020
    Assignee: Board of Regents, The University of Texas System
    Inventors: Aria Nosratinia, Mohamed Fadel Shady
  • Patent number: 10682339
    Abstract: Embodiments of the current invention include methods and compositions for regulating the activity of hormone receptors.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: June 16, 2020
    Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Marc Cox, Artem Cherkasov
  • Publication number: 20200184130
    Abstract: Systems and methods for simulating subterranean regions having multi-scale fracture geometries. Non-intrusive embedded discrete fracture modeling formulations are applied to two-dimensional and three-dimensional unstructured grids, with mixed elements, using an element-based finite-volume method in conjunction with commercial simulators to model subsurface characteristics in regions having complex hydraulic fractures, complex natural fractures, or a combination of both.
    Type: Application
    Filed: December 2, 2019
    Publication date: June 11, 2020
    Applicants: Sim Tech LLC, Board of Regents, The University of Texas System
    Inventors: Kamy Sepehrnoori, Yifei Xu, Wei Yu, Francisco Marcondes, Jijun Miao
  • Publication number: 20200181201
    Abstract: The present disclosure provides ?2?-1 C-terminal domain mimetics for the treatment of pain, epilepsy or other disorders in a subject. Further provided is an ?2?-1 C-terminal domain peptide which blocks binding of ?2?-1 to the glutamate receptors NMDAR and AMPAR.
    Type: Application
    Filed: August 14, 2018
    Publication date: June 11, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventor: Hui-lin PAN
  • Publication number: 20200184587
    Abstract: A system and computerized method for managing faculty resources includes providing an input/output interface, a memory, and one or more processors communicably coupled to the input/output interface and the memory, providing a faculty database structure communicably coupled to the one or more processors and one or more databases, wherein the faculty database structure comprises a faculty profile for each faculty member that links personal data, position data, evaluation criteria and performance data together for the faculty member, selecting one or more of the faculty profiles using the input/output interface, determining a performance score for each selected faculty profile by comparing the performance data to the evaluation criteria using the one or more processors, and providing the performance score for each selected faculty profile to the input/output interface.
    Type: Application
    Filed: December 5, 2019
    Publication date: June 11, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Mark Schultze, Todd Leach, Michelle Moreno, David L. Callender
  • Publication number: 20200181385
    Abstract: Methods and compositions directed to blends of acrylonitrile butadiene styrene (ABS) with styrene ethylene butadiene styrene (SEBS) are disclosed. In certain aspects, the blends further include an ultrahigh molecular weight polyethylene (UHMWPE). In a further aspect, the blends are compatible with 3D printing platforms.
    Type: Application
    Filed: August 15, 2016
    Publication date: June 11, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: David A. Roberson, Kevin Schnittker, Jose Gilberto Siqueiros
  • Publication number: 20200179642
    Abstract: Disclosed herein are devices, methods, and systems for monitoring the position of a subjects head and/or provide instruction to bring the subject's head into a desired position, to perform a desired movement, or a series of head positions and/or movements.
    Type: Application
    Filed: July 6, 2017
    Publication date: June 11, 2020
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Maria Stephanie JARDELEZA, Henrick Youval KRIGEL
  • Patent number: 10675038
    Abstract: Provided herein are methods, compositions, and devices for occluding cavities or passageways in a patient, in particular cavities or passageways in the cardiovascular system of a patient, such as the LAA of a patient's heart. The methods, compositions, and devices can be used to percutaneously occlude the LAA, decreasing the risk of thromboembolic events associated with AF.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: June 9, 2020
    Assignees: Applied Cardiovascular Solutions, LLC, Board of Regents, The University of Texas System
    Inventors: F. Javier Otero, Joseph J. Beaman, Krishnendu Roy, Andrew Zimbroff
  • Publication number: 20200170749
    Abstract: Apparatus and methods for providing three-dimensional printed oral stents are provided for head and neck radiotherapy. Movement of the jaw of the patient is simulated via a computer processor. Simulating movement of the jaw of the patient comprises rotating and translating a mandible of the jaw. A digital negative impression is transformed into a digital oral stent by adding support structures to the digital negative impression. The support structures facilitate three-dimensional (3D) printing of the patient-specific oral stent.
    Type: Application
    Filed: July 17, 2018
    Publication date: June 4, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Eugene Jon KOAY, Caroline CHUNG, Christopher T. WILKE, Clifton David FULLER, Mohamed ZAID
  • Patent number: 10667754
    Abstract: A thin-film, diaphragm based device is disclosed which can be used to perform an array of sensing and actuating operations where a very thin profile is desired, such as in millimeter, micrometer, or nanometer tight spaces.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: June 2, 2020
    Assignee: The Board of Regents of The University of Texas System
    Inventors: Peter Starr, Steven Bailey, Mauli Agrawal