Abstract: A method including receiving, from a C-arm device, a plurality of fluoroscopic images of a lung, wherein each fluoroscopic image is obtained with the C-arm device positioned at a particular pose of a plurality of poses traversed by the C-arm device while the C-arm device is moved through a range of motion including a range of rotation, the range of rotation encompassing a sweep angle between 45 degrees and 120 degrees; generating an enhanced tomographic image of the lung, by utilizing: a trained machine learning model and the plurality of fluoroscopic images; and outputting a representation of the enhanced tomographic image, wherein, when tested by a method in which: the lung includes a lesion smaller than 30 millimeters, and the representation is an axial slice showing a boundary of the lesion, the lesion has a contrast-to-noise value of at least 5 as compared to a background of the representation.

Abstract: The present invention is disclosing several methods related to intra-body navigation of radiopaque instrument through natural body cavities. One of the methods is disclosing the pose estimation of the imaging device using multiple images of radiopaque instrument acquired in the different poses of imaging device and previously acquired imaging. The other method allows to resolve the radiopaque instrument localization ambiguity using several approaches, such as radiopaque markers and instrument trajectory tracking.

Abstract: The present invention provides a method, including: obtaining a first image from a first imaging modality; identifying on the first image from the first imaging modality obtaining a second image from a second imaging modality; generating a compatible virtual image from the first image from the first imaging modality; mapping planning data on the compatible virtual image; coarse registering of the second image from the second imaging modality to the first image from the first imaging modality; identifying at least one element of the mapped planning data from the compatible virtual image; identifying at least one corresponding element on the second imaging modality; mapping the at least one corresponding element on the second imaging modality; fine registering of the second image from the second imaging modality to the first image from the first imaging modality; generating a third image.

Abstract: A device for use during a medical imaging process, the device including a support structure and a plurality of radiopaque markers, the support structure configured to be positioned in proximity to at least a portion of a body of a patient during the medical imaging process, the plurality of radiopaque markers attached to the support structure, the plurality of radiopaque markers being positioned in a pattern such that an image capturing a given portion of the pattern is unique from an image capturing any other given portion of the pattern.

Abstract: The present invention is disclosing several methods related to intra-body navigation of radiopaque instrument through natural body cavities. One of the methods is disclosing the pose estimation of the imaging device using multiple images of radiopaque instrument acquired in the different poses of imaging device and previously acquired imaging. The other method allows to resolve the radiopaque instrument localization ambiguity using several approaches, such as radiopaque markers and instrument trajectory tracking.

Abstract: A method, including obtaining at least one preoperative image from an imaging modality; identifying, on the at least one preoperative image, at least one element located within an area of interest; obtaining at least one intraoperative image; highlighting the at least one element on the at least one intraoperative image; navigating a radial endobronchial ultrasound probe to the area of interest using the at least highlighted at least one element; acquiring a plurality of radial endobronchial ultrasound images; extracting a plurality of two-dimensional representations of the element, each of the plurality of two-dimensional representations of the element being extracted from a corresponding one of the plurality of radial endobronchial ultrasound images; reconstructing a three-dimensional representation of the element from the plurality of two-dimensional representations of the element; and projecting a two-dimensional projection of the three-dimensional representation of the element on at least one of the at l

Abstract: The present invention provides a method, including: introducing an instrument into a cavity of a subject; obtaining a first image from a first imaging modality; identifying on the first image from the first imaging modality at least one element, obtaining a second image from a second imaging modality; generating a compatible virtual image from the first image from the first imaging modality; mapping planning data on the compatible virtual image; coarse registering of the second image from the second imaging modality to the first image from the first imaging modality; identifying at least one element of the mapped planning data from the compatible virtual image; identifying a corresponding element on the second imaging modality; mapping the corresponding element on the second imaging modality; fine registering of the second image from the second imaging modality to the first image from the first imaging modality; generating a third image.

Abstract: The present invention provides a method, including: obtaining a first image from a first imaging modality; identifying on the first image from the first imaging modality obtaining a second image from a second imaging modality; generating a compatible virtual image from the first image from the first imaging modality; mapping planning data on the compatible virtual image; coarse registering of the second image from the second imaging modality to the first image from the first imaging modality; identifying at least one element of the mapped planning data from the compatible virtual image; identifying at least one corresponding element on the second imaging modality; mapping the at least one corresponding element on the second imaging modality; fine registering of the second image from the second imaging modality to the first image from the first imaging modality; generating a third image.

Abstract: The present invention is disclosing several methods related to intra-body navigation of radiopaque instrument through natural body cavities. One of the methods is disclosing the pose estimation of the imaging device using multiple images of radiopaque instrument acquired in the different poses of imaging device and previously acquired imaging. The other method allows to resolve the radiopaque instrument localization ambiguity using several approaches, such as radiopaque markers and instrument trajectory tracking.

Abstract: In some embodiments, the instant invention provides a device including: (a) at least one sleeve composed of a material configured to exhibit a sufficient flexibility to reduce tissue damage; (b) a locking mechanism configured to secure the at least one sleeve into a position complementary to a bronchial airway; (c) a plurality of locatable elements; and where the size of the at least one sleeve is sufficient to be introduced into the bronchial airway.

Abstract: The present invention provides a method, including: obtaining a first image from a first imaging modality; identifying on the first image from the first imaging modality obtaining a second image from a second imaging modality; generating a compatible virtual image from the first image from the first imaging modality; mapping planning data on the compatible virtual image; coarse registering of the second image from the second imaging modality to the first image from the first imaging modality; identifying at least one element of the mapped planning data from the compatible virtual image; identifying at least one corresponding element on the second imaging modality; mapping the at least one corresponding element on the second imaging modality; fine registering of the second image from the second imaging modality to the first image from the first imaging modality; generating a third image.