Patents Assigned to Boehringer Ingelheim Pharma KG
  • Intermediates useful for preparing 4,6-diaminopyrido[5,4-d]pyrimidines
    Patent number: 6849734
    Abstract: 2-Chloro-4,6-diamino-7,8-dihydropyrimido[5,4-d]pyrimidine of the formula II wherein R1 denotes a hydrogen atom or a C1-C6 alkyl group, R2 denotes an optionally substituted C6-C10 aryl group, R3 denotes a hydrogen atom or a C1-C6 alkyl group, and R4 denotes a hydrogen atom or an optionally substituted C1-C6 alkyl, C3-C6 alkenyl, C3-C8 cycloalkyl or a 4- to 7-membered, nitrogen-containing heterocyclyl group, or R3 and R4 together with the nitrogen atom linked to them denote an optionally substituted heterocyclyl group, and PG1 denotes a C1-6 alkanoyl group.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: February 1, 2005
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Werner Belzer, Ralf Lock, Werner Rall
  • Fluorenecarboxylic acid esters, process for the manufacture thereof, and use thereof as medicaments
    Publication number: 20050020622
    Abstract: Fluorenecarboxylic acid esters of general formula 1 wherein X? and the groups A, R, R1, R2, R3, R3?, R4, and R4? have the meanings given in the claims and in the specification, processes for the manufacture thereof and the use thereof as medicaments.
    Type: Application
    Filed: August 9, 2004
    Publication date: January 27, 2005
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Sabine Germeyer, Helmut Meissner, Gerd Morschhaeuser, Sabine Pestel, Michael Pieper, Gerald Pohl, Richard Reichl, Georg Speck
  • Medical formulation containing a muscarinic agonist
    Publication number: 20050008703
    Abstract: A film-coated tablet containing talsaclidine comprising: (a) a core comprising talsaclidine or a physiologically acceptable acid addition salt thereof; and (b) a film coating, wherein the film coating envelops the core.
    Type: Application
    Filed: August 2, 2004
    Publication date: January 13, 2005
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Karoline Bechtold-Peters, Thomas Friedl, Michael Walz
  • Substituted phenylamidines medicaments containing said compounds and method for production thereof
    Patent number: 6838460
    Abstract: The present invention relates to phenylamidines of general formula wherein R6 and R7 are defined as in claim 1, the tautomers, the stereoisomers including mixtures thereof and the salts thereof, particularly their physiologically acceptable salts with inorganic or organic acids or bases, which have valuable pharmacological properties, preferably antithrombotic effects, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
    Type: Grant
    Filed: January 13, 2001
    Date of Patent: January 4, 2005
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Frank Himmelsbach, Brian Guth
  • Method for identifying substances which positively influence inflammatory conditions of chronic inflammatory airway diseases
    Publication number: 20040253630
    Abstract: The present invention relates to substances which modulate receptors involved in inflammatory processes and whose modulated functions positively influence inflammatory diseases.
    Type: Application
    Filed: June 22, 2004
    Publication date: December 16, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Birgit Jung, Norbert Kraut, Stefan Mueller, Barbara Kistler, Peter Seither, Karsten Quast, Andreas Weith
  • Substituted piperazine derivatives, the preparation thereof and their use as medicaments
    Patent number: 6821967
    Abstract: The present invention relates to substituted piperazine derivatives of general formula wherein Ra, Rb, Rc, Rf, Rg, X, m and n are defined as in claim 1, the isomers and salts thereof, particularly the physiologically acceptable salts thereof, which are valuable inhibitors of the microsomal triglyceride-transfer protein (MTP), medicaments containing these compounds and their use, as well as the preparation thereof.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: November 23, 2004
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Thorsten Lehmann-Lintz, Armin Heckel, Leo Thomas, Michael Mark
  • Inhalable powder containing tiotropium
    Publication number: 20040228806
    Abstract: The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use in preparing a pharmaceutical composition for the treatment of respiratory complaints, particularly for the treatment of COPD (chronic obstructive pulmonary disease) and asthma.
    Type: Application
    Filed: December 5, 2003
    Publication date: November 18, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Karoline Bechtold-Peters, Michael Walz, Georg Boeck, Rolf Doerr
  • Process for preparing vanillylamine hydrochloride
    Publication number: 20040225155
    Abstract: Process for preparing vanillylamine or one of the salts thereof by reacting vanillin with hydroxylamine or the salts thereof in the presence of an organic salt, which may optionally be produced in situ, wherein the reaction is carried out in an inorganic or organic acid as diluent, and subsequently hydrogenating the resulting vanillyloxime with hydrogen in the presence of a suitable catalyst and an organic and/or inorganic acid.
    Type: Application
    Filed: June 9, 2004
    Publication date: November 11, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Oliver Meyer, Ingo Heddesheimer
  • Fluorenecarboxylic acid esters, process for the manufacture thereof, and use thereof as medicaments
    Patent number: 6815452
    Abstract: Fluorenecarboxylic acid esters of general formula 1 wherein X− and the groups A, R, R1, R2, R3, R3′, R4, and R4′ have the meanings given in the claims and in the specification, processes for the manufacture thereof and the use thereof as medicaments.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: November 9, 2004
    Assignee: Boehringer Ingelheim Pharma KG & Co GmbH
    Inventors: Sabine Germeyer, Helmut Meissner, Gerd Morschhaeuser, Sabine Pestel, Michael P. Pieper, Gerald Pohl, Richard Reichl, Georg Speck
  • Stainless steel canister for propellant-driven metering aerosols
    Publication number: 20040211411
    Abstract: The present invention relates to corrosion resistant stainless steel canisters for propellant-containing aerosol formulations for use in propellant gas-operated inhalers.
    Type: Application
    Filed: May 20, 2004
    Publication date: October 28, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Hubert Hoelz, Richard Thomas Lostritto, Juergen Nagel, Julio Cesar Vega
  • Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
    Patent number: 6806272
    Abstract: The present invention relates to new dihydropteridinones of the formula (I) wherein the groups X, R1, R2, R3, R4, R5 and R7 have the meanings given in the claims and the specification, the isomers thereof, processes and intermediates for preparing these dihydropteridinones as well as the use thereof as pharmaceutical compositions.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: October 19, 2004
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Eckhart Bauer, Steffen Breitfelder, Christian Eickmeier, Matthias Grauert, Matthias Hoffmann, Thorsten Lehmann-Lintz, Gerald Pohl, Jens Quant, Norbert Redemann, Gisela Schnapp, Martin Steegmaier
  • Method of treating schizophrenia
    Patent number: 6800623
    Abstract: A method for treating schizophrenia which comprises administering a compound of general formula (I)
    Type: Grant
    Filed: January 6, 2003
    Date of Patent: October 5, 2004
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Karin Winter, Thomas Weiser, Stefan M. Blech, Angelo Ceci
  • Pharmaceutical compositions containing tiotropium salts and antihistamines and their use
    Publication number: 20040192675
    Abstract: A pharmaceutical composition comprising a tiotropium salt; and an antihistamine, optionally together with a pharmaceutically acceptable excipient, the tiotropium salt and the antihistamine optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of respiratory tract diseases.
    Type: Application
    Filed: April 14, 2004
    Publication date: September 30, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Michel Pairet, Michael P. Pieper, Christopher John Montague Meade, Christel Schmelzer
  • Polymers based on N-carbamyl-N'-dimethylsilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries
    Publication number: 20040186243
    Abstract: The present invention relates to polymers characterised by novel silicon linkers based on the carbamyl piperazine moiety, methods of preparing these polymers and their use in the solid phase synthesis of compounds or libraries of compounds embracing a phenyl ring in their structure.
    Type: Application
    Filed: January 29, 2004
    Publication date: September 23, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Enzo Cereda, Carlo Maria Pellegrini, Monica Quai, Walter Barbaglia
  • Fluorenecarboxylic acid esters, process for the manufacture thereof, and use thereof as medicaments
    Patent number: 6790856
    Abstract: Flourenecarboxylic acid esters of general formula 1 wherein X− and the groups A, R, R1, R2, R3, R3′, R4, and R4′ have the meanings given in the claims and in the specification, processes for the manufacture thereof and the use thereof as medicaments.
    Type: Grant
    Filed: January 2, 2003
    Date of Patent: September 14, 2004
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Sabine Germeyer, Helmut Meissner, Gerd Morschhaeuser, Sabine Pestel, Michael P. Pieper, Gerald Pohl, Richard Reichl, Georg Speck
  • Pharmaceutical compositions based on anticholinergics and corticosteroids
    Publication number: 20040176338
    Abstract: A pharmaceutical composition comprising an anticholinergic and a steroid, optionally together with a pharmaceutically acceptable excipient, the anticholinergic and the steroid optionally in the form of their enantiomers, mixtures of their enantiomers, their racemates, their solvates, or their hydrates, processes for preparing them, and their use in the treatment of respiratory tract diseases.
    Type: Application
    Filed: February 11, 2004
    Publication date: September 9, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Michel Pairet, Michael P. Pieper, Christopher John Montague Meade, Richard Reichl, Christel Schmelzer
  • Pharmaceutical compositions based on anticholinergic and dopamine agonists
    Publication number: 20040161386
    Abstract: The present invention relates to novel pharmaceutical compositions based on anticholinergics and dopamine agonists, processes for preparing them and their use in the treatment of respiratory tract diseases.
    Type: Application
    Filed: February 10, 2004
    Publication date: August 19, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Michel Pairet, Michael P. Pieper, Christopher J. Montague Meade
  • Crystalline form of telmisartan sodium
    Publication number: 20040162327
    Abstract: The invention relates to a crystalline sodium salt of 4′-[2-n-propyl-4-methyl-6-(1-methyl-benzimidazol-2-yl)benzimidazol-1-ylmethyl]biphenyl-2-carboxylic acid (INN: telmisartan), processes for preparing it and the use thereof for preparing a pharmaceutical composition.
    Type: Application
    Filed: February 12, 2004
    Publication date: August 19, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Kai Donsbach, Irmgard Hof
  • Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions
    Patent number: 6777423
    Abstract: Crystalline monohydrate of (1&agr;,2&bgr;,4&bgr;,5&agr;,7&bgr;)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide (tiotropium bromide monohydrate), processes for the preparation thereof, pharmaceutical compositions thereof, and their use.
    Type: Grant
    Filed: January 30, 2003
    Date of Patent: August 17, 2004
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Rolf Banholzer, Peter Sieger, Christian Kulinna, Michael Trunk, Manfred Graulich, Peter Specht, Helmut Meissner, Andreas Mathes
  • Fluorenecarboxylic acid esters, process for the manufacture thereof, and use thereof as medicaments
    Publication number: 20040157832
    Abstract: Fluorenecarboxylic acid esters of general formula 1 1
    Type: Application
    Filed: February 5, 2004
    Publication date: August 12, 2004
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Sabine Germeyer, Helmut Meissner, Gerd Morschhauser, Sabine Pestel, Michael P. Pieper, Gerald Pohl, Richard Reichl, Georg Speck