Patents Assigned to Brookhaven Science Associates
  • Patent number: 9383452
    Abstract: A drift detector array, preferably a silicon drift detector (SDD) array, that uses a low current biasing adaptor is disclosed. The biasing adaptor is customizable for any desired geometry of the drift detector single cell with minimum drift time of carriers. The biasing adaptor has spiral shaped ion-implants that generate the desired voltage profile. The biasing adaptor can be processed on the same wafer as the drift detector array and only one biasing adaptor chip/side is needed for one drift detector array to generate the voltage profiles on the front side and back side of the detector array.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: July 5, 2016
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Zheng Li, Wei Chen
  • Publication number: 20160187270
    Abstract: A long-range method and a system for reliably detecting and identifying special nuclear materials is provided that relies on the emission of delayed neutrons present in the decay of fission products (delayed neutron precursors) as a unique signature for the special nuclear materials, such as highly enriched uranium (235/238U). The method relies on a time-of-flight measurement in the first 1 ?s after the inducing radiation pulse, and pulse height data analysis for both neutrons and gamma rays that can be done at a much higher data rate than in traditional pulse processing systems. The thermal neutron fission within the time regime of 100-500 ?s provides a unique signature of special nuclear materials such as the highly enriched uranium.
    Type: Application
    Filed: February 4, 2016
    Publication date: June 30, 2016
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Istvan Dioszegi, Leon Forman, Peter E. Vanier, Cynthia A. Salwen
  • Publication number: 20160181449
    Abstract: This disclosure provides embodiments of photovoltaic devices. The devices include a light-absorbing anode comprised of an electrically conductive material having a plasmonic structure, a diffusion barrier, and a cathode. The light-absorbing anode and the cathode are separated by the diffusion barrier.
    Type: Application
    Filed: November 19, 2015
    Publication date: June 23, 2016
    Applicant: BROOKHAVEN SCIENCE ASSOCIATES, LLC
    Inventors: Charles T. Black, Matthew Sfeir
  • Publication number: 20160160376
    Abstract: An apparatus for the synthesis and treatment of electrocatalyst particles in batch or continuous fashion is provided. In one embodiment, the apparatus is comprised of a three-electrode cell which includes a cell body electrode, a reference electrode and a floating counter electrode. The floating counter electrode may be disposed inside a counter electrode compartment which is adapted to float in a slurry containing a plurality of nanoparticles and an electrolyte.
    Type: Application
    Filed: November 19, 2015
    Publication date: June 9, 2016
    Applicant: BROOKHAVEN SCIENCE ASSOCIATES, LLC
    Inventors: Radoslav Adzic, Junliang Zhang, Kotaro Sasaki
  • Publication number: 20160135765
    Abstract: An Active Water Phantom is designed to provide fast, accurate, high resolution, complete Quality Assurance of patient-specific treatment plans utilizing intensity-modulated Ion Beam Therapy, prior to their delivery to the patient. The detection medium is a tissue-equivalent water-based liquid scintillator material. A three-dimensional pattern of scintillation light, emitted upon ion beam irradiation, is reconstructed from three orthogonal two-dimensional light yield profiles, which are read out for each individual beam energy layer. The 3-D information has dose measurement accuracy 1-2% and spatial resolution 1-2 millimeters. The measurement sequence provides up to four orders of magnitude more data characterizing the treatment plan than currently commercially available alternatives, all in a time period no greater than that needed for actual delivery of the dose fraction to a patient.
    Type: Application
    Filed: November 19, 2014
    Publication date: May 19, 2016
    Applicants: Phenix Medical LLC, Brookhaven Science Associates, LLC
    Inventors: Steven E. Vigdor, Minfang Yeh, David E. Jaffe
  • Publication number: 20160139302
    Abstract: Technologies are described for methods and systems effective for etching nanostructures in a substrate. The methods may comprise depositing a patterned block copolymer on the substrate. The patterned block copolymer may include first and second polymer block domains. The methods may comprise applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer. The precursor may infiltrate into the first polymer block domain and generate a material in the first polymer block domain. The methods may comprise applying a removal agent to the infiltrated block copolymer to generate a patterned material. The removal agent may be effective to remove the first and second polymer block domains from the substrate. The methods may comprise etching the substrate. The patterned material on the substrate may mask the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 19, 2016
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Charles T. Black, Atikur Rahman, Matthew Eisaman, Ahsan Ashraf
  • Patent number: 9340776
    Abstract: Compositions and methods include genetically encoding and expressing a novel ?9-18:0-ACP desaturase in plant cells. In some embodiments, nucleic acid molecules encode the novel ?9-18:0-ACP desaturase. In other embodiments, amino acid sequences have ?9-18:0-ACP desaturase activity. Methods can involve expression of ?9-18:0-ACP desaturase in plant cells, plant materials, and whole plants for the purpose of increasing the amount of unusual fatty acids in whole plants, plant seeds, and plant materials, for example, seeds.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: May 17, 2016
    Assignees: Dow AgroSciences LLC, Brookhaven Science Associates, LLC
    Inventors: John Shanklin, Tam Huu Nguyen, Terence A. Walsh, Mark S. Pidkowich, Edward J. Whittle
  • Patent number: 9335423
    Abstract: A radiation detector device is provided that is capable of distinguishing between full charge collection (FCC) events and incomplete charge collection (ICC) events based upon a correlation value comparison algorithm that compares correlation values calculated for individually sensed radiation detection events with a calibrated FCC event correlation function. The calibrated FCC event correlation function serves as a reference curve utilized by a correlation value comparison algorithm to determine whether a sensed radiation detection event fits the profile of the FCC event correlation function within the noise tolerances of the radiation detector device. If the radiation detection event is determined to be an ICC event, then the spectrum for the ICC event is rejected and excluded from inclusion in the radiation detector device spectral analyses. The radiation detector device also can calculate a performance factor to determine the efficacy of distinguishing between FCC and ICC events.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: May 10, 2016
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Aleksey E. Bolotnikov, Gianluigi De Geronimo, Emerson Vernon, Ge Yang, Giuseppe Camarda, Yonggang Cui, Anwar Hossain, Ki Hyun Kim, Ralph B. James
  • Patent number: 9303073
    Abstract: The invention relates to the development of chimeric OspA molecules for use in a new Lyme vaccine. More specifically, the chimeric OspA molecules comprise the proximal portion from one OspA serotype, together with the distal portion from another OspA serotype, while retaining antigenic properties of both of the parent polypeptides. The chimeric OspA molecules are delivered alone or in combination to provide protection against a variety of Borrelia genospecies. The invention also provides methods for administering the chimeric OspA molecules to a subject in the prevention and treatment of Lyme disease or borreliosis.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: April 5, 2016
    Assignees: BAXALTA INCORPORATED, BAXALTA GMBH, Research Foundation of the State University of New York, Brookhaven Science Associates, LLC
    Inventors: Brian A. Crowe, Ian Livey, Maria O'Rourke, Michael Schwendinger, John J. Dunn, Benjamin J. Luft
  • Publication number: 20160013605
    Abstract: Technologies are described for methods and systems effective to compress an input pulse to produce an output pulse. The methods may include receiving, by a pulse compressor, the input pulse. The methods may further include producing, by the pulse compressor, an unchirped portion of the input pulse. The methods may further include producing, by the pulse compressor, a chirped portion of the input pulse. The methods may further include filtering out, by the pulse compressor, the unchirped portion. The methods may further include compressing, by the pulse compressor, the chirped portion to produce the output pulse.
    Type: Application
    Filed: July 7, 2015
    Publication date: January 14, 2016
    Applicant: Brookhaven Science Associates, LLC
    Inventor: Mikhail Polyanskiy
  • Publication number: 20160002651
    Abstract: In the tgd1-1 mutant that displays substantially enhanced TAG synthesis and turnover, disruption of SUGAR-DEPENDENT1 (SDP1) TAG lipase or PEROXISOMAL TRANSPORTER1 (PXA1) severely decreases FA turnover, leading to an increase in leaf TAG content up to 9% of dry weight and total leaf lipid by three-fold. The membrane lipid content and composition of tgd1-1 sdp1-4 and tgd1-1 pxa1-2 double mutants are altered and they are compromised in growth and development and fertility.
    Type: Application
    Filed: July 2, 2015
    Publication date: January 7, 2016
    Applicant: Brookhaven Science Associates, LLC
    Inventors: Changcheng Xu, Jilian Fan, Chengshi Yan, John Shanklin
  • Publication number: 20150376803
    Abstract: Highly effective, standalone gas-diffusion electrodes (GDEs) and the methods for their manufacture and test are disclosed, Nanocataiysis are directly bonded on a gas diffusion layer, so that the integrity of the catalyst layer holds without polymer electrolyte membrane, facilitating minimization of electronic, prottmtc, and diffusion resistances in the catalyst layer. The devised embodiments provide examples showing a facile hanging-strip method for testing the standalone GDEs in a solution electrochemical cell, which removes the mA-cm?2-scale mass transport limited currents on rotating disk electrodes to allow studies of reaction kinetics on single electrode over sufficiently wide current ranges (up to A cm?2) without mass transport limitation. Ultralow-Pi-content GDEs are fabricated as the cathode for hydrogen evolution in water eiectrolyzers and as the anode for hydrogen oxidation in hydrogen fuel cells.
    Type: Application
    Filed: October 9, 2013
    Publication date: December 31, 2015
    Applicant: Brookhaven Science Associates, LLC
    Inventor: Jia Xu Wang
  • Patent number: 9224570
    Abstract: A vacuum encapsulated, hermetically sealed cathode capsule for generating an electron beam of secondary electrons, which generally includes a cathode element having a primary emission surface adapted to emit primary electrons, an annular insulating spacer, a diamond window element comprising a diamond material and having a secondary emission surface adapted to emit secondary electrons in response to primary electrons impinging on the diamond window element, a first high-temperature solder weld disposed between the diamond window element and the annular insulating spacer and a second high-temperature solder weld disposed between the annular insulating spacer and the cathode element.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: December 29, 2015
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Triveni Rao, John Walsh, Elizabeth Gangone
  • Patent number: 9225325
    Abstract: Embodiments of comparator circuits are disclosed. A comparator circuit may include a differential input circuit, an output circuit, a positive feedback circuit operably coupled between the differential input circuit and the output circuit, and a hysteresis control circuit operably coupled with the positive feedback circuit. The hysteresis control circuit includes a switching device and a transistor. The comparator circuit provides sub-hysteresis discrimination and high speed discrimination.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: December 29, 2015
    Assignee: Brookhaven Science Associates, LLC
    Inventor: Gianluigi De Geronimo
  • Patent number: 9221957
    Abstract: Technologies are described for methods for producing a pattern of a material on a substrate. The methods may comprise receiving a patterned block copolymer on a substrate. The patterned block copolymer may include a first polymer block domain and a second polymer block domain. The method may comprise exposing the patterned block copolymer to a light effective to oxidize the first polymer block domain in the patterned block copolymer. The method may comprise applying a precursor to the block copolymer. The precursor may infuse into the oxidized first polymer block domain and generate the material. The method may comprise applying a removal agent to the block copolymer. The removal agent may be effective to remove the first polymer block domain and the second polymer block domain from the substrate, and may not be effective to remove the material in the oxidized first polymer block domain.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: December 29, 2015
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Chang-Yong Nam, Jovan Kamcev, Charles T. Black, Robert Grubbs
  • Patent number: 9193972
    Abstract: A nucleotide construct comprising a nucleotide sequence that forms a stem and a loop, wherein the loop comprises a nucleotide sequence that modulates expression of a target, wherein the stem comprises a nucleotide sequence that modulates expression of a target, and wherein the target modulated by the nucleotide sequence in the loop and the target modulated by the nucleotide sequence in the stem may be the same or different. Vectors, methods of regulating target expression, methods of providing a cell, and methods of treating conditions comprising the nucleotide sequence are also disclosed.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: November 24, 2015
    Assignee: Brookhaven Science Associates, LLC
    Inventors: John Shanklin, Tam Huu Nguyen
  • Patent number: 9150968
    Abstract: High-surface-area carbon nanostructures coated with a smooth and conformal submonolayer-to-multilayer thin metal films and their method of manufacture are described. The manufacturing process may involve initial oxidation of the carbon nanostructures followed by immersion in a solution with the desired pH to create negative surface dipoles. The nanostructures are subsequently immersed in an alkaline solution containing non-noble metal ions which adsorb at surface reaction sites. The metal ions are then reduced via chemical or electrical means and the nanostructures are exposed to a solution containing a salt of one or more noble metals which replace adsorbed non-noble surface metal atoms by galvanic displacement. Subsequent film growth may be performed via the initial quasi-underpotential deposition of a non-noble metal followed by immersion in a solution comprising a more noble metal.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: October 6, 2015
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Radoslav R. Adzic, Alexander Harris
  • Patent number: 9153453
    Abstract: A process is disclosed for sectioning by etching of monolayers and multilayers using an RIE technique with fluorine-based chemistry. In one embodiment, the process uses Reactive Ion Etching (RIE) alone or in combination with Inductively Coupled Plasma (ICP) using fluorine-based chemistry alone and using sufficient power to provide high ion energy to increase the etching rate and to obtain deeper anisotropic etching. In a second embodiment, a process is provided for sectioning of WSi2/Si multilayers using RIE in combination with ICP using a combination of fluorine-based and chlorine-based chemistries and using RF power and ICP power. According to the second embodiment, a high level of vertical anisotropy is achieved by a ratio of three gases; namely, CHF3, Cl2, and O2 with RF and ICP. Additionally, in conjunction with the second embodiment, a passivation layer can be formed on the surface of the multilayer which aids in anisotropic profile generation.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: October 6, 2015
    Assignees: Brookhaven Science Associates, LLC, UChicago Argonne, LLC
    Inventors: Nathalie C. D. Bouet, Raymond P. Conley, Ralu Divan, Albert Macrander
  • Patent number: 9134439
    Abstract: A radiation detector system that effectively solves the electron trapping problem by optimizing shielding of individual virtual Frisch-grid detectors in an array configuration with a common cathode.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: September 15, 2015
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Aleksey Bolotnikov, Ralph B. James, Gianluigi De Geronimo, Emerson Vernon
  • Publication number: 20150252484
    Abstract: A catalytic composition from earth-abundant transition metal salts and biomass is disclosed. A calcined catalytic composition formed from soybean powder and ammonium molybdate is specifically exemplified herein. Methods for making the catalytic composition are disclosed as are electrodes for hydrogen evolution reactions comprising the catalytic composition.
    Type: Application
    Filed: October 1, 2013
    Publication date: September 10, 2015
    Applicant: BROOKHAVEN SCIENCE ASSOCIATES LLC
    Inventors: Wei-Fu Chen, Shweta Iyer, Shilpa Iyer, Kotaro Sasaki, James T. Muckerman, Etsuko Fujita